The document provides a brief overview of COVID-19, including its origin as SARS-CoV-2, symptoms, and suggested preventative measures. It discusses the historical context of coronaviruses and notes the absence of specific antiviral treatments or vaccines at this time, with oxygen therapy being the main intervention for severe cases. Additionally, it summarizes experimental treatments that have been proposed for COVID-19.

1. COVID 19- A Short Briefing
Dr. Mithil S. Fal Desai
Assistant Professor in Chemistry
SHREE MALLIKARJUN
&
Shri Chetan Manju Desai College
Canacona Goa
Content : About the Name COVID 19, Coronavirus, Types of corona virus, How it
reached us, precaution, experimental medicine, end of the video research articles
from which we collected this information.

2. The Name COVID 19
• Initially, virus was labelled as 2019-nCoV.
• International Committee on Taxonomy of Viruses
designated it as the SARS-CoV-2 virus.
• February 2020, World Health Organization (WHO)
announced the disease caused by SARS-CoV-2
novel virus as Coronavirus disease-2019 (COVID-
19).

3. Coronavirus
• Coronavirus (CoV) is a large family, single-
stranded RNA viruses that belong to the
Nidovirales order.

4. Coronavirus is not alone

5. History and Origin
• SARS-CoV caused severe acute respiratory
syndrome outbreaks in 2002 and 2003 in
Guangdong Province, China.
• MERS-CoV severe respiratory disease
outbreaks in 2012 in Middle East.
• SARS-CoV-2 out break in December 2019,
Wuhan China

6. How it reached US?

7. Consequence of COVID 19
Chest Radiographs. Shown are chest radiographs from Patient 2 on days 8 and 11 after the onset of illness. The trachea
was intu-bated and mechanical ventilation instituted in the period between the acquisition of the two images. Bilateral
fluffy opacities are present in both images but are in-creased in density, profusion, and confluence in the second image;
these changes are most marked in the lower lung fields. Changes consistent with the accumu-lation of pleural liquid are
also visible in the second image.
Symtoms: Cold, Fever, body pain, difficulty in breathing

8. Corona Replication Mechanism

9. Precaution is only cure
• Avoid close contact with subjects suffering from acute
respiratory infections.
• Wash your hands frequently
• Avoid unprotected contact with farm or wild animals.
There is no specific antiviral treatment recommended
for COVID-19, and no vaccine is currently available.
Oxygen therapy represents the major treatment
intervention for patients with severe infection.

10. Experimental medicine
Inappropriate administration of antibiotics
should be avoided,
*’’Although no antiviral treatments have been
approved, several approaches have been
proposed such as lopinavir/ritonavir (400/100
mg every 12 hours), chloroquine (500 mg every
12 hours), and hydroxychloroquine (200 mg
every 12 hours). Alpha-interferon (e.g., 5
million units by aerosol inhalation twice per day)
is also used.’’

11. All summarized from following articles
1) Chen Y, Liu Q, Guo D: Emerging coronaviruses: genome
structure, replication, and pathogenesis. J Med Virol. 2020,
92:418-423. 10.1002/jmv.25681
2) Cascella M, Rajnik M, Cuomo A, Dulebohn SC, Napoli RD:
Features, Evaluation and Treatment Coronavirus (COVID-19).
StatPearls Publishing, Treasure Island, FL; 2020.
3) Fehr AR, Perlman S: Coronaviruses: an overview of their
replication and pathogenesis.Methods Mol Biol. 2015, 1282:1-
23. 10.1007/978-1-4939-2438-7_1
4) Yingying Cong , Pauline Verlhac and Fulvio Reggiori , Viruses
2017, 9(7), 182; https://doi.org/10.3390/v9070182
5) Drs. Zhu, Zhang, W. Wang, Li, and Yang; N Engl J Med
2020;382:727-33. DOI: 10.1056/NEJMoa2001017