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Measurement of corneal
topography:
Videokeratography
Jeewanand Bist
References
 Borish’s Clinical Refraction, Benjamin
Franklin.
 A Guide to Videokeratography, Clinical
article; ICLC, vol.23, Nov/Dec, 1996.
 Corneal Disorders; Clinical Management
& Diagnosis; 2nd edition; Howard M.
Leibowitz & Georgo O. WaringIII.
 Internet
Videokeratoscopy
 Considerable qualitative data
can be derived from inspection
of the keratoscopic images
when distortions are large.
 For large distortions
quantitative analysis of
keratoscopic images is
necessary.
 A videokeratograph results from
a videokeratoscope working in
conjunction with a computer.
History
 In 1980s keratorefractive surgery
provided impetus for development of
better methods for clinicians for
evaluation of corneal topography.
 1987- color topographic maps have
become the standard method for
displaying the output of computerized
videokeratoscopes.
History contd…
 First computerized videokeratoscope –
the corneal Modelling System (CMS) by
Computed Anatomy (Gormley et.al
1988).
 EyeSys System 2000 (EyeSys
Technologies) added side cameras that
simultaneously view the cornea in
profile.
Principle
 It is based on the concept of
photokeratoscopy. (difference???)
 Video camera substituted for the
photographic camera.
 It has more advantage than
photokeratoscope.
 Videokeratography provides reasonable
accuracy & repeatability in measuring corneal
topography.
Principle
 Principle same as keratometer.
 A luminous object (target of rings) is
placed in front of patient’s cornea, and the
image size produced in the corneal
reflection is measured.
 It assumes cornea as the convex mirror &
makes use of the first purkinje image.
What is the use when it is
based on the same principle of
keratometer????
 Keratometer measurement is restricted to a
small central corneal area (3-3.5mm).
 It measures corneal curvature at two
positions in each principal meridians. (4
paracentral points).
 Modern viedeokeratoscopes evaluate several
thousands of points from nearly the entire
corneal surface.
 They measure the entire corneal contour.
Keratometric measurement of
corneal topography
Procedure
 Aligning the subject’s eye in front of the instrument
so that it is centered with respect to instrument.
 Focusing for the corneal image of the target rings.
 Freezing the corneal image by the video camera.
 Image is captured & displayed on a computer screen.
 If the image is unacceptable, it may be discarded
procedure repeated.
 Small areas may be missed.
 In dry eyes lubricating drops should be instilled.
Instrument design
 The Tomey
Topographic
Modelling System
(TMS)
 Small target.
 Short working
distance.
Instrument design
 The EyeSys 2000
Corneal Analysis
System
 Large target.
 Larger working
distance.
Keratograph Algorithms
 Process of building a topographic map of
cornea from keratoscopic data goes through
following general steps:
 Capture video images of the keratoscope rings.
 Measure angular size of points on the rings.
 Reconstruct the corneal surface point by point.
 Assign dioptric or other descriptors for each
surface.
 Present surface descriptors in a color topographic
map.
Display Options
 Simulated keratometry
 This display gives values that are meant to
be equivalent of a keratometer reading for
each of the two principal meridians.
 It is produced simply by taking the radius
value from the target ring that corresponds
to the corneal positions where the
reflection takes place from the keratometer
mires.
Display Options
 Profile plot
 Shows a plot of radius of curvature (or
power) values with respect to distance
from the center of the corneal map in each
of the two principal meridian.
Display Options
 The Corneal Map
 Most common & most
important display.
 It allows the clinician to
visualize the overall
characteristics of the
corneal contour & to
detect various corneal
anomalies.
Mapping of Cornea
 Surface Elevation Maps
 Because surface shape is the primary determinant
of corneal optics (Applegat 1994: Applegate &
Howland 1995), a logical way to map the cornea is
to show the relative surface elevation of each
point from a reference surface.
 Surface elevation are mapped relative to a
reference sphere, ellipsoid or other surface that
approximates the corneal shape. (Salmon &
Horner 1995)
 Elevations measured from a plane are nearly
useless as minute elevations are lost.
Surface Elevation maps
 Dioptric Corneal Maps
 Corneal topography is expressed in terms
of local dioptric values rather than surface
elevations.
 The dioptric maps “speak the language” of
keratometry with which clinicians are
already familiar. (Roberts, 1994a)
 Axial Curvatural Maps
 Axial radius also known as the sagittal radius is
the distance along a normal from the point on the
cornea to the optic axis of videokeratograph when
it is aligned with the cornea.
 It is the radius that is measured in keratometry &
was the first radius used in videokeratography.
 It assumes corneal surface as a spherical surface
& this assumption is acceptable for keratometry.
 Introduces major error in videokeratography.
 Instantaneous Curvatural Maps
 Instantaneous radius is independent of any axis &
is based on only the local curvature at each
corneal point.
 It is also known as the ‘tangential’, ‘local’, or ‘true’
radius.
 With peripheral corneal flattening, the
instantaneous radius will always be longer than
the axial radius for each peripheral corneal point.
Axial Vs Instantaneous
curvatural maps
Comparison of different
curvatural maps
 Surface elevation maps show fine
details of corneal surface.
 Particularly useful in the pre-operative &
post-operative management of refractive
surgery patients.
 Monitoring surface anamolies such as
keratoconus.
 Custom-contact lens design.
Comparison of different
Curvatural maps…
 Dioptric maps are most familiar & effectively
display changes in corneal contour.
 Useful in monitoring surface shape changes as seen in
keratoconus or in contact lens induced distortion.
 Instantaneous curvature map is more sensitive to
subtle changes than axial curvature maps but is
also more subject to noisy data.
 Axial curvatural maps are used to verify aspheric
contact lens base curve.
Interpretation of corneal maps
 Each color corresponds to certain
dioptric power range.
 Cold colors (black, blue, azure)
 Represent flatter surfaces with less
dioptric value.
 Warm colors (orange, red, white)
 Represent steeper surfaces with
greater dioptric value.
 Color belonging to central part of
visible spectrum (green, yellow)
represent surfaces with normal
values.
Uses of videokeratography
 To know corneal topography in different
corneal degenerations & dystrophies.
 Early detection of ectatic conditions of cornea
like keratoconus, Pellucid Marginal
Degeneration etc.
 In cases of trauma.
 Evaluating post-op evaluation of refractive
surgeries & penetrating keratoplasty.
Topography of Normal Cornea
 Bogan & co-workers
 Round
 Oval pattern represent
corneas with very low
astigmatism.
 Bow- tie patterns indicate
astigmatism
Corneal topography in
astigmatism
 Difference in curvature
of two principal corneal
meridians represented
as bow-tie pattern.
 Bow-tie is oriented
along the steeper
meridian.
Corneal topography in
astigmatism
Corneal topography in
keratoconus
 Keratoconus is a condition
which is characterized by a
non-inflammatory thinning
and steepening of the central
and/or para-central cornea.
 The condition usually
results in a moderate to marked
decrease in visual acuity
secondary irregular astigmatism
and corneal scarring.
Bilateral keratoconus
 Central & para-central steepening (???)
 Areas beyond central & paracentral area
affects the corneal topography
significantly.
Early keratoconus
 Pear shaped infero-
temporal paracentral
steepening.
 Progresses nasally.
 Superior cornea
remains relatively
intact.
Early keratoconus
In early keratoconus, there is a characteristic steepening of
the inferior cornea with a subsequent flattening of the
 Rotational steepening
occurs at and above the
midline.
 Includes the temporal,
superior-temporal, and
superior cornea.
 The superior-nasal
quadrant of the cornea is
always the last to be
affected.
 Modern topographic techniques have
demonstrated that in early keratoconus
there is a characteristic steepening
initially occurring mid-peripherally below
the corneal midline
Topographical shapes of
advanced keratoconus
 Nipple
 Oval
 Globus
Nipple-Shaped Topography
 The nipple form of
keratoconus
characteristically
consists of a small,
near central ectasia,
less than 5.0 mm in
cord diameter
Nipple-shaped keratoconus may also manifest as a small
central ectasia with moderate to high with-the-rule corneal
Oval shaped topography
 The most common
corneal shape noted in
advanced keratoconus is
oval topography.
 In oval-form
keratoconus, the corneal
apex is displaced well
below the midline
resulting in varying
degrees of inferior mid-
peripheral steepening.
Globus-shaped topography
 The globus form of keratoconus affects
the largest area of the cornea, often
encompassing nearly three quarters of
the corneal surface.
Why to talk so much on
keratoconus????
 Keratoconus accounts
for about 15% of all
corneal transplants.
 Early detection is
crucial.
 Progression can be
checked by contact
lenses.
Intra-palpebral, three-point
touch fitting technique for
early keratoconus
Pellucid Marginal Degeneration
 Pellucid Marginal
Degeneration (PMD) is
a bilateral corneal
disorder hallmarked by
a thinning of the inferior
peripheral cornea.
 The corneal thinning
begins approximately
1.0 to 2.0 mm above
the inferior limbus.
Corneal topography in Pellucid
Marginal Degeneration
Corneal topography in Pellucid
Marginal Degeneration
 High against the rule
astigmatism
 Inferior mid-
peripheral
steepening at 4 & 8
o’clock position.
 Kissing pigeon
pattern (diagnostic
of PMD)
Typical kissing pigeon
appearance
Topography in Terrien’s
Marginal Degeneration
 TMD usually involves the
superior periphery.
 Flattening in the involved
meridian & steepening along
90* away from the ectasia.
 If disease confined to small
corneal arc topography
simulates PMD.
 If involves larger corneal arc,
it simulates keratoconus.
Corneal topography in
pterygium
 Pterygium is a triangular
sheet of fibrovascular
tissue which invades
cornea.
 Invades cornea from
nasal or temporal sides.
 Typical with-the-rule
astigmatism is induced.
 Bow-tie pattern oriented
vertically.
Topography in Traumatic cases
 Corneal topography in
cases of trauma depends
upon
 Location
 Severity(extent & depth)
 Type of trauma
 Flattening along the
meridian of laceration &
steepening along 90* away.
Limitations of
videokeratoscopy
 Measures the contour of peripheral
cornea less accurately than that of the
central.
 Inability to directly measure the optical
performance of complex surface
patterns generated by penetrating
keratoplasty or refractive surgical
procedures.
Future Developments
 Rasterstereography
 Tear film is dyed with fluorescein.
 Projects a grid of horizontal & vertical lines onto
the corneal surface & visualizes the image of
transparent cornea.
 Image is captured by video camera & processed
by a computer.
 Analysis of the distance & position of the
projected mires provide data of on the height of
surface at various points rather than on the
curvature.
 Independent of superficial defects or irregularities.
 Laser interferometry
 Holography
Thanks !!!

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Corneal topography...ppt

  • 2. References  Borish’s Clinical Refraction, Benjamin Franklin.  A Guide to Videokeratography, Clinical article; ICLC, vol.23, Nov/Dec, 1996.  Corneal Disorders; Clinical Management & Diagnosis; 2nd edition; Howard M. Leibowitz & Georgo O. WaringIII.  Internet
  • 3. Videokeratoscopy  Considerable qualitative data can be derived from inspection of the keratoscopic images when distortions are large.  For large distortions quantitative analysis of keratoscopic images is necessary.  A videokeratograph results from a videokeratoscope working in conjunction with a computer.
  • 4. History  In 1980s keratorefractive surgery provided impetus for development of better methods for clinicians for evaluation of corneal topography.  1987- color topographic maps have become the standard method for displaying the output of computerized videokeratoscopes.
  • 5. History contd…  First computerized videokeratoscope – the corneal Modelling System (CMS) by Computed Anatomy (Gormley et.al 1988).  EyeSys System 2000 (EyeSys Technologies) added side cameras that simultaneously view the cornea in profile.
  • 6. Principle  It is based on the concept of photokeratoscopy. (difference???)  Video camera substituted for the photographic camera.  It has more advantage than photokeratoscope.  Videokeratography provides reasonable accuracy & repeatability in measuring corneal topography.
  • 7. Principle  Principle same as keratometer.  A luminous object (target of rings) is placed in front of patient’s cornea, and the image size produced in the corneal reflection is measured.  It assumes cornea as the convex mirror & makes use of the first purkinje image.
  • 8. What is the use when it is based on the same principle of keratometer????  Keratometer measurement is restricted to a small central corneal area (3-3.5mm).  It measures corneal curvature at two positions in each principal meridians. (4 paracentral points).  Modern viedeokeratoscopes evaluate several thousands of points from nearly the entire corneal surface.  They measure the entire corneal contour.
  • 10. Procedure  Aligning the subject’s eye in front of the instrument so that it is centered with respect to instrument.  Focusing for the corneal image of the target rings.  Freezing the corneal image by the video camera.  Image is captured & displayed on a computer screen.  If the image is unacceptable, it may be discarded procedure repeated.  Small areas may be missed.  In dry eyes lubricating drops should be instilled.
  • 11. Instrument design  The Tomey Topographic Modelling System (TMS)  Small target.  Short working distance.
  • 12. Instrument design  The EyeSys 2000 Corneal Analysis System  Large target.  Larger working distance.
  • 13. Keratograph Algorithms  Process of building a topographic map of cornea from keratoscopic data goes through following general steps:  Capture video images of the keratoscope rings.  Measure angular size of points on the rings.  Reconstruct the corneal surface point by point.  Assign dioptric or other descriptors for each surface.  Present surface descriptors in a color topographic map.
  • 14. Display Options  Simulated keratometry  This display gives values that are meant to be equivalent of a keratometer reading for each of the two principal meridians.  It is produced simply by taking the radius value from the target ring that corresponds to the corneal positions where the reflection takes place from the keratometer mires.
  • 15. Display Options  Profile plot  Shows a plot of radius of curvature (or power) values with respect to distance from the center of the corneal map in each of the two principal meridian.
  • 16. Display Options  The Corneal Map  Most common & most important display.  It allows the clinician to visualize the overall characteristics of the corneal contour & to detect various corneal anomalies.
  • 17. Mapping of Cornea  Surface Elevation Maps  Because surface shape is the primary determinant of corneal optics (Applegat 1994: Applegate & Howland 1995), a logical way to map the cornea is to show the relative surface elevation of each point from a reference surface.  Surface elevation are mapped relative to a reference sphere, ellipsoid or other surface that approximates the corneal shape. (Salmon & Horner 1995)  Elevations measured from a plane are nearly useless as minute elevations are lost.
  • 19.  Dioptric Corneal Maps  Corneal topography is expressed in terms of local dioptric values rather than surface elevations.  The dioptric maps “speak the language” of keratometry with which clinicians are already familiar. (Roberts, 1994a)
  • 20.  Axial Curvatural Maps  Axial radius also known as the sagittal radius is the distance along a normal from the point on the cornea to the optic axis of videokeratograph when it is aligned with the cornea.  It is the radius that is measured in keratometry & was the first radius used in videokeratography.  It assumes corneal surface as a spherical surface & this assumption is acceptable for keratometry.  Introduces major error in videokeratography.
  • 21.  Instantaneous Curvatural Maps  Instantaneous radius is independent of any axis & is based on only the local curvature at each corneal point.  It is also known as the ‘tangential’, ‘local’, or ‘true’ radius.  With peripheral corneal flattening, the instantaneous radius will always be longer than the axial radius for each peripheral corneal point.
  • 23. Comparison of different curvatural maps  Surface elevation maps show fine details of corneal surface.  Particularly useful in the pre-operative & post-operative management of refractive surgery patients.  Monitoring surface anamolies such as keratoconus.  Custom-contact lens design.
  • 24. Comparison of different Curvatural maps…  Dioptric maps are most familiar & effectively display changes in corneal contour.  Useful in monitoring surface shape changes as seen in keratoconus or in contact lens induced distortion.  Instantaneous curvature map is more sensitive to subtle changes than axial curvature maps but is also more subject to noisy data.  Axial curvatural maps are used to verify aspheric contact lens base curve.
  • 25. Interpretation of corneal maps  Each color corresponds to certain dioptric power range.  Cold colors (black, blue, azure)  Represent flatter surfaces with less dioptric value.  Warm colors (orange, red, white)  Represent steeper surfaces with greater dioptric value.  Color belonging to central part of visible spectrum (green, yellow) represent surfaces with normal values.
  • 26. Uses of videokeratography  To know corneal topography in different corneal degenerations & dystrophies.  Early detection of ectatic conditions of cornea like keratoconus, Pellucid Marginal Degeneration etc.  In cases of trauma.  Evaluating post-op evaluation of refractive surgeries & penetrating keratoplasty.
  • 27. Topography of Normal Cornea  Bogan & co-workers  Round  Oval pattern represent corneas with very low astigmatism.  Bow- tie patterns indicate astigmatism
  • 28. Corneal topography in astigmatism  Difference in curvature of two principal corneal meridians represented as bow-tie pattern.  Bow-tie is oriented along the steeper meridian.
  • 30. Corneal topography in keratoconus  Keratoconus is a condition which is characterized by a non-inflammatory thinning and steepening of the central and/or para-central cornea.  The condition usually results in a moderate to marked decrease in visual acuity secondary irregular astigmatism and corneal scarring.
  • 32.  Central & para-central steepening (???)  Areas beyond central & paracentral area affects the corneal topography significantly.
  • 33. Early keratoconus  Pear shaped infero- temporal paracentral steepening.  Progresses nasally.  Superior cornea remains relatively intact.
  • 34. Early keratoconus In early keratoconus, there is a characteristic steepening of the inferior cornea with a subsequent flattening of the
  • 35.  Rotational steepening occurs at and above the midline.  Includes the temporal, superior-temporal, and superior cornea.  The superior-nasal quadrant of the cornea is always the last to be affected.
  • 36.  Modern topographic techniques have demonstrated that in early keratoconus there is a characteristic steepening initially occurring mid-peripherally below the corneal midline
  • 37. Topographical shapes of advanced keratoconus  Nipple  Oval  Globus
  • 38. Nipple-Shaped Topography  The nipple form of keratoconus characteristically consists of a small, near central ectasia, less than 5.0 mm in cord diameter
  • 39. Nipple-shaped keratoconus may also manifest as a small central ectasia with moderate to high with-the-rule corneal
  • 40. Oval shaped topography  The most common corneal shape noted in advanced keratoconus is oval topography.  In oval-form keratoconus, the corneal apex is displaced well below the midline resulting in varying degrees of inferior mid- peripheral steepening.
  • 41.
  • 42. Globus-shaped topography  The globus form of keratoconus affects the largest area of the cornea, often encompassing nearly three quarters of the corneal surface.
  • 43. Why to talk so much on keratoconus????  Keratoconus accounts for about 15% of all corneal transplants.  Early detection is crucial.  Progression can be checked by contact lenses. Intra-palpebral, three-point touch fitting technique for early keratoconus
  • 44. Pellucid Marginal Degeneration  Pellucid Marginal Degeneration (PMD) is a bilateral corneal disorder hallmarked by a thinning of the inferior peripheral cornea.  The corneal thinning begins approximately 1.0 to 2.0 mm above the inferior limbus.
  • 45. Corneal topography in Pellucid Marginal Degeneration
  • 46. Corneal topography in Pellucid Marginal Degeneration  High against the rule astigmatism  Inferior mid- peripheral steepening at 4 & 8 o’clock position.  Kissing pigeon pattern (diagnostic of PMD)
  • 48. Topography in Terrien’s Marginal Degeneration  TMD usually involves the superior periphery.  Flattening in the involved meridian & steepening along 90* away from the ectasia.  If disease confined to small corneal arc topography simulates PMD.  If involves larger corneal arc, it simulates keratoconus.
  • 49. Corneal topography in pterygium  Pterygium is a triangular sheet of fibrovascular tissue which invades cornea.  Invades cornea from nasal or temporal sides.  Typical with-the-rule astigmatism is induced.  Bow-tie pattern oriented vertically.
  • 50. Topography in Traumatic cases  Corneal topography in cases of trauma depends upon  Location  Severity(extent & depth)  Type of trauma  Flattening along the meridian of laceration & steepening along 90* away.
  • 51. Limitations of videokeratoscopy  Measures the contour of peripheral cornea less accurately than that of the central.  Inability to directly measure the optical performance of complex surface patterns generated by penetrating keratoplasty or refractive surgical procedures.
  • 52. Future Developments  Rasterstereography  Tear film is dyed with fluorescein.  Projects a grid of horizontal & vertical lines onto the corneal surface & visualizes the image of transparent cornea.  Image is captured by video camera & processed by a computer.  Analysis of the distance & position of the projected mires provide data of on the height of surface at various points rather than on the curvature.  Independent of superficial defects or irregularities.