Cor pulmonale is defined as right ventricular hypertrophy and eventual failure due to pulmonary hypertension, most commonly secondary to COPD. Clinical features include decreased exercise tolerance, cyanosis, and signs of right ventricular failure, with diagnosis supported by imaging techniques such as chest X-ray and echocardiogram. Treatment focuses on managing the underlying pulmonary disorder and careful use of oxygen therapy, diuretics, and digoxin when necessary.

1. Cor Pulmonale
Ghadeer Ismail Eideh
Supervised by Dr. Ashraf Zughair
19-sep-2022
From: step up to medicine

2. Definition and
causes
Clinical features
Diagnosis Treatment
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03
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04
Outlines

3. 1. is defined as right ventricular hypertrophy with
eventual RV failure resulting from pulmonary
HTN, secondary to pulmonary disease.
2. The definition does not encompass any of the
causes of pulmonary HTN due to left-sided heart
disease (such as mitral stenosis or left-to-right
shunts).
Definition

4. 1. It is most commonly secondary to
COPD.
2. Other causes include recurrent
PE, ILD, asthma, CF, sleep apnea,
and pneumoconioses.
Causes:

6. Clinical features
1 .Decrease in exercise tolerance
2. Cyanosis and digital clubbing
3. Signs of right ventricular failure: hepatomegaly, edema, JVD
4. Parasternal lift

7. 1. CXR: enlargement of the RA, RV, and pulmonary arteries
2. ECG: right-axis deviation, P Pulmonale (peaked P waves), right
ventricular hypertrophy
3. Echocardiogram: right ventricular dilatation, but normal LV size
and function; useful in excluding LV dysfunction
Diagnosis

8. Apply continuous long-
term oxygen therapy if the
patient is hypoxic.
Treat the underlying
pulmonary disorder
Use diuretic therapy
cautiously because patients
may be preload dependent.
Administer digoxin only if
there is coexistent LV
failure
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04
Treatment
05
A variety of vasodilators
have been studied; no
definite improvement has
been shown with their use.

9. Thank you.