During the Middle Ages in Europe between 1000-1500 CE: 1) Trade revival led to the growth of cities and towns which became centers of manufacturing and commerce. 2) Europe experienced many hardships in the 14th-15th centuries including the Black Death plague, which killed over half the population in some areas, the Hundred Years War between England and France, and decline of the Catholic Church. 3) Advances in farming technology and policies led to increases in food production and a near doubling of Europe's population from 38 to 74 million.