The Black Death consisted of three plagues - Bubonic, Pneumonic, and Septicemic - caused by the Yersinia pestis bacteria, which was transmitted via fleas living on rats. The Bubonic plague was the most common type and symptoms included fever, chills, and swollen lymph nodes called buboes. It killed an estimated 100,000 people in the 1665 Plague of London. The Black Death had lasting effects on European civilization through population decline, economic impacts, and changes in art and literature.
PowerPoint: Medieval Life: The Black Death - Bubonic Plague - Black PlagueYaryalitsa
PowerPoint looks generally at THE BLACK DEATH. It includes links to the History Channel's 18 part series: The Plague. It also includes an Assessment Task for students to complete.
A Time of Turmoil
The French Revolution was one of the most influential events of modern history. The ten year period from 1789 to 1799 when France went from a Monarchy to a Republic, to a Reign of Terror, to Dictatorship was one of the most tumultuous times in European history.
Myth and Reality
Much myth and romantic legend has been written on what some politicians would like the French Revolution to have been, but the reality was that the French Revolution was a monstrous horror. In the name of “liberty, equality, fraternity or death!” over 40,000 people lost their heads to the guillotine, 300,000 people were publically executed by firing squads, drownings and other methods of mass murder and ultimately many millions died in the 25 years of war and upheavals that resulted.
PowerPoint: Medieval Life: The Black Death - Bubonic Plague - Black PlagueYaryalitsa
PowerPoint looks generally at THE BLACK DEATH. It includes links to the History Channel's 18 part series: The Plague. It also includes an Assessment Task for students to complete.
A Time of Turmoil
The French Revolution was one of the most influential events of modern history. The ten year period from 1789 to 1799 when France went from a Monarchy to a Republic, to a Reign of Terror, to Dictatorship was one of the most tumultuous times in European history.
Myth and Reality
Much myth and romantic legend has been written on what some politicians would like the French Revolution to have been, but the reality was that the French Revolution was a monstrous horror. In the name of “liberty, equality, fraternity or death!” over 40,000 people lost their heads to the guillotine, 300,000 people were publically executed by firing squads, drownings and other methods of mass murder and ultimately many millions died in the 25 years of war and upheavals that resulted.
Presentation given by Carlos Lurigados from Biocat in the framework of the Emergence Forum Barcelona
Biocat organized the Barcelona Emergence Forum (April 10-11th, 2014, Congress Palace, Montjuïc) supported by the TRANSBIO SUDOE, a translational cooperation project dedicated to innovation in life sciences in South-West Europe. The Barcelona Emergence Forum contributed to bringing together Academics, Companies, Investment Entities, Technology Platforms and Technology Transfer Offices from Spain, France and Portugal to set up collaborative projects on Human Health & Agro-food Innovation.
More information at: http://www.b2match.eu/emergenceforum2014
La nanobiomedicina és una de les fortaleses de la recerca a Catalunya, comunitat que ha estat pionera dins l’Estat en crear centres focalitzats en la integració multidisciplinar de nano i biotecnologia, i que actualment són referents internacionals.
En base a aquestes potencialitats, impulsades per les entitats que fan recerca en nanotecnologia i nanobiomedicina, s’ha constituït BioNanoMed Catalunya, aliança de la nanobiomedicina a Catalunya, que neix amb el propòsit de desenvolupar d’impulsar aquest sector dins de la BioRegió de Catalunya.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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2. The Black Death The Black Death consisted of three Plagues, the Septicaemic Plague, Pneumonic Plague and the worst of all the Bubonic Plague. Also the path of the Black Death and where it came from. Plus the impact it had on Europe.
3. Yersinia Pestis Yersinia Pestis was the main cause behind the Black Death because it was the Bacteria in all of the three Plagues. Yersinia Pestis was transferred by Fleas that live on rats. The fleas would then bite into humans infecting them with the Plagues. The plagues were then transferred from person to person in different ways.
4. Septicaemic One of the least common plagues was the Septicaemic Plague. This is caught by a flea that is infected with Yersinia Pestis bites a human and the infected blood coming from the flea gets into the bloodstream This was transferred by fleas biting humans
5. Pneumonic plague This Plague was not the most common but was not the least common either. The Pneumonic Plague causes bleeding in the lungs. It is pass from person to person when people cough or sneeze. If the water droplets contain Yersinia Pestis then the person who is breathing the germs in becomes infected.
6. Bubonic The most common plague was the Bubonic Plague. This was caught by people handling rodents such as rats and squirrels that had fleas carrying Yersinia Pestis and were bitten by them.
7. Symptoms The symptoms of the plagues were that it started with a headache, then chills and fevers quickly followed. Within a day or two swellings started to appear these were hard lumps that would appear on the neck, under arms and on the inner thighs. These would then turn black and burst open to begin oozing pus and blood. They would then start to bleed internally and if it was the Pneumonic plague they would bleed in their lungs. It was possible to recover but it was almost certain that anyone who was unlucky enough to get infected would die.
9. Plague of London In 1665 the Black Death got a new name, The Plague of London. It was named this when in came back in another major outbreak. This outbreak last just 1 year but in this time it killed 100,000 people. The Plague of London ended in 1666 when the Great fire of London burned down most of the city killing most of the plague carrying rats.
10. Effect on European Civilization The Effect on the European Civilization was huge. It effected the population, economy the church and art works. People at the time would have been very scared and the Children which would not have been able to cope with all the dying going on all around them.
11. Effect on Art The effect on art was great because there was a great depression at the time and if some one did paint anything is was going to be a sad painting surrounded by death. The painting to the left was painted at the time and is proof that there was a effect on art.
12. Effect on Children The effect on children was very large. A common nursery rhyme is proof of this. Ring a-round the rosy Pocket full of posies Ashes, ashes! We all fall down! The rosy means the rosary beads that give you gods help. Posies was a Flower they used to try to mask the smell and thought that if they could hide the smell they would not get infected. Ashes is the church burning the dead, and We all fall down means them dying.
13. Long lasting effects Some of the long lasting effects was the population, which took 400 years to return to the numbers before the Black Death, but one of the most hardest hit was the economy. This was because after the black death a lot of the people with skills died. This meant that if you had skills you were more valuable than that of the rich people. This cause everything to shift, meaning formally poor people now had a lot more say in things. The peasants then demanded higher wages. Because the lords didn’t want to pay more a lot of the farming villages died out.
14. Plague today Sadly the Black Plague is not gone for good, there have been smaller outbreaks one was in India where 900 people died in 1994. Although there have not been any major outbreaks of the Plague recently in 2002 two residents of New York caught the plague in New Mexico.
15. Conclusion In my opinion this sort of plague is still around us today but it is a lot more controlled. Proof of this is the two people in New York who caught it in New Mexico. But I don’t think that it is ever going to have the effect it had on Europe again.