The Black Death arrived in Europe in 1347 from Central Asia, carried by fleas on black rats. Over the next three years, it killed an estimated 25-50 million people across Europe, anywhere from one-third to one-half of the total population. Transmitted through flea bites and respiratory droplets, the plague's symptoms included fever, chills, vomiting and the appearance of swollen and infected lymph nodes. While it left devastating social, economic and political impacts, some areas fared better through early quarantines and isolation practices. The Black Death remained a threat in Europe for centuries and still occurs sporadically today.