Cerebral Palsy: Classification
By: vaibhav mittal
introduction
• The term cerebral palsy
was first used in 1843
by the English
orthopedic surgeon
William Little in a series
of lectures entitled
“Deformities of the
Human Frame”
• It was known for many
years as “Little’s
disease”
introduction
• Cerebral palsy is a heterogeneous disorder of
movement and posture that has a wide
variety of presentations, ranging from mild
motor disturbance to severe total body
involvement.
Distinctive features
• There are three distinctive features common to all
patients with cerebral palsy:
(1) some degree of motor impairment, versus autism;
(2) an insult to the developing brain, making it different
from conditions that affect the mature brain in older
children and adults; and
(3) a neurological deficit that is nonprogressive, versus
other motor diseases of childhood, such as the
muscular dystrophies
Age
• The insult to the brain is believed to occur
between the time of conception and age 2
years, at which time a significant amount of
motor development has already occurred
• By 8 years of age, most of the development of
the immature brain is complete, as is gait
development, and an insult to the brain
results in a more adult-type clinical picture
and outcome.
ORTHOPAEDICS ASPECTS
• Although the neurological deficit is permanent and
nonprogressive, the effect it can have on the patient is
dynamic, and the orthopaedic aspects of cerebral palsy
can change dramatically with growth and development
• Growth, along with altered muscle forces across joints,
can lead to
(1)progressive loss of motion,
(2)contracture, and eventually
(3)joint subluxation or dislocation, resulting in
(4)degeneration, that may require orthopaedic
intervention
ETIOLOGY
• Injury to the developing brain can occur at any
time from gestation to early childhood and
typically is categorized as
1)Prenatal
2)Perinatal
3)Postnatal
• This includes risk factors inherent to the fetus
(most commonly genetic disorders)
• Factors inherent to the mother (seizure disorders,
mental retardation, and previous pregnancy loss)
• Factors inherent to the pregnancy itself (Rh
incompatibility, polyhydramnios placental
rupture, and drug or alcohol exposure).
• Trauma, head injury Infections Lack of oxygen
Stroke in the young, Tumor, cyst
• External factors, such as TORCH syndrome
(toxoplasmosis, other agents, rubella,
cytomegalovirus, herpes simplex), also can lead
to cerebral palsy in th prenatal period.
• Oxytocin augmentation, umbilical cord prolapse,
and breech presentation all have been associated
with an increased occurrence of cerebral palsy.
• Hypoxic-ischemic encephalopathy, which is
characterized by hypotonia, decreased
movement, and seizures, is a common cause of
cerebral palsy during the postnatal period.
Classification
• Because of the wide variability in presentation and types of
cerebral palsy, there is no universally accepted classification
scheme
• Cerebral palsy can be classified by the
(1) the region of the body affected.
(2) the neuroanatomical region of the brain that was injured
It also can be classified
(3) temporally in relation to the time of birth, as previously
Described.
Hemiplegia
In hemiplegia, one side of the body is involved,
with the upper extremity usually more affected
than the lower extremity.
Patients with hemiplegia, approximately 30% of
patients with cerebral palsy, typically have
sensory changes in the affected extremities as
well.
Hemiplegia
limbs on only one side
Diplegia
Diplegia is the most common anatomical type
of cerebral palsy, constituting approximately
50% of all cases.
Patients with diplegia have motor abnormalities
in all four extremities, with the lower
extremities more affected than the upper.
The close proximity of the lower extremity tracts
to the ventricles most likely explains the more
frequent involvement of the lower extremities
with periventricular lesions
Diplegia/ Paraplegia
•both legs•both legs w/ slight
involvement
elsewhere
This type of cerebral palsy is most common in
premature infants
Intelligence usually is normal.
Most children with diplegia walk eventually,
although walking is delayed usually until around
age 4 years.
Quadriplegia
In quadriplegia, all four extremities are equally
involved, and many patients have significant
cognitive deficiencies that make care more
difficult
Head and neck control usually are present,
which helps with communication, education,
and seating.
Quadriplegia
Physiological Classification
Physiologically, cerebral palsy can be divided into a
(1)spastic type, which affects the corticospinal
(pyramidal) tracts, and
(2)an extrapyramidal type, which affects the other
regions of the developing brain
• The extrapyramidal types of cerebral palsy include
(1)athetoid
(2)choreiform
(3)ataxic
(4)rigid
(5)hypotonic
Physiological Classification
3 MAIN TYPES
1. PYRAMIDAL
- originates from the motor areas
of the cerebral cortex
2. EXTAPYRAMIDAL
- basal ganglia and cerebellum
3. MIXED
Spastic CP
• Increased muscle tone,
tense and contracted muscles
– Have stiff and jerky or
awkward movements.
– limbs are usually
underdeveloped
– increased deep tendon
reflexes
• most common form
• 70-80% of all affected
Booth showed histologically
that this altered muscle
function leads to the
deposition of type I collagen in
the endomysium of the
affected muscle, leading to
thickening and fibrosis, the
degree of which correlated to
the severity of the spasticity.
Joint contractures,
subluxation, and degeneration
are common in patients with
spastic cerebral palsy.
Athetoid/ Dyskinetic CP
• Fluctuating tone
– involves abnormal involuntary
movements
– that disappear during sleep and
increase with stress.
– Interferes with speaking, feeding,
reaching, grabbing, and any other
skills
– 20% of the CP cases,
Choreiform
Choreiform cerebral palsy is characterized by
continual purposeless movements of the
patient's wrists, fingers, toes, and ankles. This
continuous movement can make bracing and
sitting difficult.
Rigid
Patients with rigid cerebral palsy are the most hypertonic
of all cerebral palsy patients.
These patients have a “cogwheel” or “lead pipe” muscle
stiffness that often requires surgical release.
Ataxic CP
• Poor balance and lack of
coordination
– Wide-based gait
– Depth perception usually affected.
– Tendency to fall and stumble
– Inability to walk straight line.
– Least common 5-10% of cases
Ataxic cerebral palsy is very rare
As a result of an injury to the
developing cerebellum.
It is important to distinguish true ataxia from
spasticity because with treatment many children
with ataxia are able to improve their gait
function without surgery.
MIXED CP
• A common combination is
spastic and athetoid
• Spastic muscle tone and involuntary
movements.
• 25% of CP cases, fairly common
Thank you…..

Cerebral palsy classification

  • 1.
  • 2.
    introduction • The termcerebral palsy was first used in 1843 by the English orthopedic surgeon William Little in a series of lectures entitled “Deformities of the Human Frame” • It was known for many years as “Little’s disease”
  • 3.
    introduction • Cerebral palsyis a heterogeneous disorder of movement and posture that has a wide variety of presentations, ranging from mild motor disturbance to severe total body involvement.
  • 4.
    Distinctive features • Thereare three distinctive features common to all patients with cerebral palsy: (1) some degree of motor impairment, versus autism; (2) an insult to the developing brain, making it different from conditions that affect the mature brain in older children and adults; and (3) a neurological deficit that is nonprogressive, versus other motor diseases of childhood, such as the muscular dystrophies
  • 5.
    Age • The insultto the brain is believed to occur between the time of conception and age 2 years, at which time a significant amount of motor development has already occurred • By 8 years of age, most of the development of the immature brain is complete, as is gait development, and an insult to the brain results in a more adult-type clinical picture and outcome.
  • 6.
    ORTHOPAEDICS ASPECTS • Althoughthe neurological deficit is permanent and nonprogressive, the effect it can have on the patient is dynamic, and the orthopaedic aspects of cerebral palsy can change dramatically with growth and development • Growth, along with altered muscle forces across joints, can lead to (1)progressive loss of motion, (2)contracture, and eventually (3)joint subluxation or dislocation, resulting in (4)degeneration, that may require orthopaedic intervention
  • 7.
    ETIOLOGY • Injury tothe developing brain can occur at any time from gestation to early childhood and typically is categorized as 1)Prenatal 2)Perinatal 3)Postnatal
  • 8.
    • This includesrisk factors inherent to the fetus (most commonly genetic disorders) • Factors inherent to the mother (seizure disorders, mental retardation, and previous pregnancy loss) • Factors inherent to the pregnancy itself (Rh incompatibility, polyhydramnios placental rupture, and drug or alcohol exposure). • Trauma, head injury Infections Lack of oxygen Stroke in the young, Tumor, cyst
  • 9.
    • External factors,such as TORCH syndrome (toxoplasmosis, other agents, rubella, cytomegalovirus, herpes simplex), also can lead to cerebral palsy in th prenatal period. • Oxytocin augmentation, umbilical cord prolapse, and breech presentation all have been associated with an increased occurrence of cerebral palsy. • Hypoxic-ischemic encephalopathy, which is characterized by hypotonia, decreased movement, and seizures, is a common cause of cerebral palsy during the postnatal period.
  • 10.
    Classification • Because ofthe wide variability in presentation and types of cerebral palsy, there is no universally accepted classification scheme • Cerebral palsy can be classified by the (1) the region of the body affected. (2) the neuroanatomical region of the brain that was injured It also can be classified (3) temporally in relation to the time of birth, as previously Described.
  • 12.
    Hemiplegia In hemiplegia, oneside of the body is involved, with the upper extremity usually more affected than the lower extremity. Patients with hemiplegia, approximately 30% of patients with cerebral palsy, typically have sensory changes in the affected extremities as well.
  • 13.
  • 14.
    Diplegia Diplegia is themost common anatomical type of cerebral palsy, constituting approximately 50% of all cases. Patients with diplegia have motor abnormalities in all four extremities, with the lower extremities more affected than the upper. The close proximity of the lower extremity tracts to the ventricles most likely explains the more frequent involvement of the lower extremities with periventricular lesions
  • 15.
    Diplegia/ Paraplegia •both legs•bothlegs w/ slight involvement elsewhere
  • 16.
    This type ofcerebral palsy is most common in premature infants Intelligence usually is normal. Most children with diplegia walk eventually, although walking is delayed usually until around age 4 years.
  • 17.
    Quadriplegia In quadriplegia, allfour extremities are equally involved, and many patients have significant cognitive deficiencies that make care more difficult Head and neck control usually are present, which helps with communication, education, and seating.
  • 18.
  • 19.
    Physiological Classification Physiologically, cerebralpalsy can be divided into a (1)spastic type, which affects the corticospinal (pyramidal) tracts, and (2)an extrapyramidal type, which affects the other regions of the developing brain • The extrapyramidal types of cerebral palsy include (1)athetoid (2)choreiform (3)ataxic (4)rigid (5)hypotonic
  • 20.
  • 21.
    3 MAIN TYPES 1.PYRAMIDAL - originates from the motor areas of the cerebral cortex 2. EXTAPYRAMIDAL - basal ganglia and cerebellum 3. MIXED
  • 22.
    Spastic CP • Increasedmuscle tone, tense and contracted muscles – Have stiff and jerky or awkward movements. – limbs are usually underdeveloped – increased deep tendon reflexes • most common form • 70-80% of all affected
  • 23.
    Booth showed histologically thatthis altered muscle function leads to the deposition of type I collagen in the endomysium of the affected muscle, leading to thickening and fibrosis, the degree of which correlated to the severity of the spasticity. Joint contractures, subluxation, and degeneration are common in patients with spastic cerebral palsy.
  • 24.
    Athetoid/ Dyskinetic CP •Fluctuating tone – involves abnormal involuntary movements – that disappear during sleep and increase with stress. – Interferes with speaking, feeding, reaching, grabbing, and any other skills – 20% of the CP cases,
  • 25.
    Choreiform Choreiform cerebral palsyis characterized by continual purposeless movements of the patient's wrists, fingers, toes, and ankles. This continuous movement can make bracing and sitting difficult.
  • 26.
    Rigid Patients with rigidcerebral palsy are the most hypertonic of all cerebral palsy patients. These patients have a “cogwheel” or “lead pipe” muscle stiffness that often requires surgical release.
  • 27.
    Ataxic CP • Poorbalance and lack of coordination – Wide-based gait – Depth perception usually affected. – Tendency to fall and stumble – Inability to walk straight line. – Least common 5-10% of cases Ataxic cerebral palsy is very rare As a result of an injury to the developing cerebellum.
  • 28.
    It is importantto distinguish true ataxia from spasticity because with treatment many children with ataxia are able to improve their gait function without surgery.
  • 30.
    MIXED CP • Acommon combination is spastic and athetoid • Spastic muscle tone and involuntary movements. • 25% of CP cases, fairly common
  • 31.