Anton van Leeuwenhoek and Robert Hooke were early pioneers in microscopy who made important discoveries about cells. Matthias Schleiden, Theodor Schwann, and Rudolph Virchow contributed to the development of the Cell Theory, which states that all living things are made of cells, cells are the basic units of structure and function, and cells only come from preexisting cells. Their combined work in microscopy and cell observation laid the foundation for understanding biology at the cellular level.