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CARDIAC ARRHYTHMIAS
Normal Heart Rate is 60-100 bpm
Every Heartbeat should originate from SA node,
Velocity should be normal,
Impulse conduction should originate from conduction
pathway.
Brady Arrhythmia(less than 60bpm) Tachy Arrhythmia(Greater than 100bpm)
Mild Bradycardia 60-40bpm Simple Tachycardia 100-150bpm
Moderate Bradycardia 40-20bpm Paroxysmal Tachycardia 150-250bpm
Severe Bradycardia 20 & less bpm Atrial Flutter 250-350bpm
Atrial Fibrillation 350 & above
Causes:
 Hypertension.
 Hyperthyroidism.
 Ischeamia & Hypoxia.
 Hypokalemia.
 Acidosis & Alkalosis.
 Patients on Digatalis therapy
 Overstretching of
myocardial contractile
fibres.
Symptoms:
 Palpitations.
 Skipping of Heart beat.
 Poor O2 supply.
 Chest pain.
 Flutters.
• Action Potential is divided to 5 phases:
Phase 0/Rapid Depolarisation
Phase 1/Partial Repolarisation
Phase 2/Plateau/ Maintained Depolarisation
Phase 3/Rapid Repolarisation
Phase 4/Diastolic Depolarisation
Electrophysiology of Cardiac Rhythm
• The normal electrocardiogram (ECG).
• The P wave results from activation
(depolarisation of the atria).
• The PR interval isisoelectric as the activation
wavefront proceeds slowly through
theatrioventricular node.
• The QRS complex reflects activation of
theventricles and is large compared to the P wave
because of the much greater mass of the
ventricular myocardium, and brief, reflecting
extremely rapid conduction in the H is–Purkinje
system.
• The T wave represents ventricular repolarisation.
Mechanism of Arrhythmias
Types of Arrhythmias
THANK YOU

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Cardiac arrhythmias--- pharmacotherapeutics-I

  • 1. CARDIAC ARRHYTHMIAS Normal Heart Rate is 60-100 bpm Every Heartbeat should originate from SA node, Velocity should be normal, Impulse conduction should originate from conduction pathway. Brady Arrhythmia(less than 60bpm) Tachy Arrhythmia(Greater than 100bpm) Mild Bradycardia 60-40bpm Simple Tachycardia 100-150bpm Moderate Bradycardia 40-20bpm Paroxysmal Tachycardia 150-250bpm Severe Bradycardia 20 & less bpm Atrial Flutter 250-350bpm Atrial Fibrillation 350 & above
  • 2. Causes:  Hypertension.  Hyperthyroidism.  Ischeamia & Hypoxia.  Hypokalemia.  Acidosis & Alkalosis.  Patients on Digatalis therapy  Overstretching of myocardial contractile fibres. Symptoms:  Palpitations.  Skipping of Heart beat.  Poor O2 supply.  Chest pain.  Flutters.
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  • 5. • Action Potential is divided to 5 phases: Phase 0/Rapid Depolarisation Phase 1/Partial Repolarisation Phase 2/Plateau/ Maintained Depolarisation Phase 3/Rapid Repolarisation Phase 4/Diastolic Depolarisation
  • 7. • The normal electrocardiogram (ECG). • The P wave results from activation (depolarisation of the atria). • The PR interval isisoelectric as the activation wavefront proceeds slowly through theatrioventricular node. • The QRS complex reflects activation of theventricles and is large compared to the P wave because of the much greater mass of the ventricular myocardium, and brief, reflecting extremely rapid conduction in the H is–Purkinje system. • The T wave represents ventricular repolarisation.
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