The document summarizes key topics in biochemistry including the regulation of blood glucose, hormonal control of blood glucose, hypoglycemia and its clinical aspects, hyperglycemia and its clinical aspects. It also includes diagrams of glucose metabolism pathways and effects of various hormones like insulin and glucagon on blood glucose levels. Tables outline the clinical manifestations of hypoglycemia and hyperglycemia. In conclusion, it provides an overview of important biochemistry concepts and regulatory mechanisms related to blood glucose homeostasis.

2. BIOCHEMISTRY

3. •Overview
•Regulation of blood glucose
•Hormonal control of blood
glucose
•Hypoglycemia and its
clinical aspect
•Hyperglycemia and its
clinical aspect
•Summary

7. Insulin Glucagon Catecholamine Glucocorticoids Growth Thyroid
s hormone hormones
Absorbtion of
glucose
Peripheral
uptake
Glycolysis
Gluconeogenes
is
glycogenesis
Glucogenolysis
Lipogenesis
Lipolysis
Protein
catabolism
Net effect on
blood glucose

8. G.H

10. These 3 is called
whipple’s triad

11. Hypoglycemia
Fasting Post parandial
Hypoglycemia Hypoglycemia
(FH) (PPH)

13. Alchohol
NAD+ lactate
Alchohol
dehydrogenase
NADH+ pyruvate
H++
acetaldehyde
NAD+ malate
Acetaldehyde
dehydrogenase
NADH+
H++
OAA
acetate
Inhibition of
gluconeogenesis
Acetyl CoA

16. Clinical Manifestations

17. These are due to
deprivation of glucose to
brain cells

18. Always
associated with
tachycardia
These are due to realease
of catecholamines
especially adrenaline

29. Biochemistry class notes (DR. Namrata)
 Internet
Respected teachers of bichemistry department