Bitter gourd is native to tropical Asia and is grown for its nutritional and medicinal properties. It is a monoecious annual climber with pentafid calyx and rotate corolla. Flowers are pollinated by honey bees and bumble bees. Breeding objectives include early fruiting, high yield, resistance to pests and diseases. Breeding methods discussed are selection, pedigree, hybridization and mutation breeding. Self-pollination and cross-pollination techniques were described to facilitate the breeding process. Overall, there is potential to improve quality and productivity through focused breeding efforts in bitter gourd.