LEARNING
OBJECTIVES
State the definition of
BENIGN PROSTATE
HYPERPLASIA.
List the etiology of
BENIGN PROSTATE
HYPERPLASIA..
Identify the
Cont.
 State the clinical
manifestation of BENIGN
PROSTATE HYPERPLASIA..
Identify the complication of
BENIGN PROSTATE
HYPERPLASIA..
Identify the nursing
intervention & appreciate the
Doctor = Dr N
Diagnosis
= BENIGN PROSTATE
HYPERPLASIA with
acute urinary
retention
Mr S was admitted to
5XX-1 with complaint of :
 Difficulty passing
urine
 Nocturia & frequency
 Urgency
 Incomplete emptying
S/B Dr N 10/7 ago (2/7/12) :
 US done findings – Grade 111 BPH.
Put on CBDand tried to removed the
CBD2/7 ago (10/7/12) but failed and
problem remained same.
 Came again to clinic 12/7/12 and
agreed forop as suggested by DrN.
ADMITTED ON 12/7/12 @ 1150H
 Mr S
 Male
 64 years old
 Pensioner
 Malay
 Wheeled in to ward
Medical history
- Diabetic (20 years)
- Hypertension (20 years)
- IHD (2009)
Surgical history
- COROS (2009) in Pantai Ipoh
Family medical history
- Unknown
Allergic
- NIL
Current Medication
- Amlodipine
- Metoprolol
- Metformin
- Daonil
- Aspirin (On admission Dr N asked
patient to stop taking)
VITAL SIGNS
Temp = 37.5˚C
Pulse = 82 bpm
Resp = 21 bpm
B/P = 170/80 mmHg
VITAL SIGNS
Weight = 62 kg
Pain Score = 2
PHYSICAL EXAMINATION
PHYSICAL EXAMINATION
•SUNKEN EYES
•DRY LIPS
 Frequency
 Urgency
 Straining
 Dribbling & poor
stream
 Nocturia
 Insomnia
Other ADL normal
ON ARRIVAL
• GXM 1 pint WB
• IV Sulperazone 1gm BD
• Ural 1/1 TDS
• Celebrex 200mg BD
• Proscar 5mg Daily
• BD dextrosmeter
• TURP under SA on 15/7/12
• Cont own medication but stop Aspirin
12/7/12 @ 2250H
• Phone noted to Dr N patient put
all medication mix together &
cannot recognize which one is
Aspirin. Dr N asked to withold all
own medication.
Phone ordered from Dr N :
• Metformin 1gm BD
• Amlodipine 7.5mg Daily
• Lovastatin 10mg ON
• Metoprolol 50mg BD
• Daonil 7.5mg BD
Understanding the prostate
Walnut-shaped gland that forms part of the
male reproductive system
Surrounds the urethra - the tube that carries
urine from the bladder out of the body


Secretes semen which
carries sperm
During orgasm, prostate
muscles contract and
propel ejaculate out of the
penis
Understanding the prostate


The size of prostate enlarged microscopically since the age
of 40.Half of all men over the age of 60 will develop an
enlarged prostate
By the time men reach their 70’s and 80’s, 80% will
experience urinary symptoms
But only 25% of men aged 80 will be receiving BPH treatment
BPH


Peripheral zone
Transition zone
Urethra
What is Benign Prostatic Hyperplasia?
Peripheral zone
Transition zone
Urethra
What causes BPH?
BPH is part of the natural aging
process, like getting gray hair
or wearing glasses
BPH cannot be prevented
BPH can be treated



SURGICAL PROFILE
Biochemistry
• Glucose 10.6 mmol/L
SURGICAL PROFILE
Microscopic Examination, urine
• WBC , urine 4/hpf
• Bacteria, urine +
CHEST X-RAY
- Normal
ECG
- Normal sinus rhythm
URINE C&S
More than 100000 cfu/ml of
Pseudomonas aeruginosa isolated.
DIGITAL RECTAL EXAMINATION
ULTRASONOGRAPHY
• To give clearer view on size and
shape and determine stages of BPH.
International Prostate Symptom
Score (IPSS)
– Symptom assessment based on questionnaires
developed by American Urological Association
(AUA).
– Contains 7 questions about severity of symptoms.
– Total score : 0–7 (mild), 8–19 (moderate), 20–35
(severe)
Prostate Specific Antigen (PSA)
– Men with larger prostates have higher PSA levels
– PSA is a predictor of disease progression and
screening tool for Ca Prostate
– As PSA values tend to increase with increasing PV
and increasing age, PSA may be used as a
prognostic marker for BPH
When should BPH be treated?
BPH needs to be treated ONLY IF:
Symptoms are severe enough to bother the
patient and affect his quality of life
Complications related to BPH


“Watchful waiting”
 Medication
 Surgical approaches
 TURP
Treatment options
Choosing the right treatment
Consider risks, benefits and
effectiveness of each
treatment
Consider the outcome and
lifestyle needs


“watchful waiting”
For mild symptoms. Follow up 1 to 2 times
yearly
Offer suggestions that help reduce
symptoms
Avoid caffeine and alcohol
Avoid decongestants and antihistamines




Medication
First line of defense against
bothersome urinary symptoms
Two major types:
α blockers - relax the smooth muscle of
prostate and provide a larger urethral
opening (Hytrin,Doxaben,Harnalidge)
5 α reductase inhibitor - Shrink
the prostate gland (Proscar,
Avodart)




Benefits
Convenient
No loss of work
time
Minimal risk
Disadvantages
Drug Interactions
Must be taken every day
Manages the problem
instead of fixing it
Medication






Possible side effects of
• Impotence
• Dizziness
• Headaches
• Fatigue
• Loss of sexual drive
medication





Distribution of α1-Adrenergic Receptors
Localization of α1-Adrenergic
Receptors (α1-ARs)
DRUGS
ORDERED ON PRE MED
DATE
ORDERED
Tab Zantac 150 mg STAT 15/7/12
Tab Maxalon 10 mg STAT 15/7/12
Tab Celebrex 200 mg STAT 15/7/12
POST OP 15/7/12 @ 1045H
- IVD 3 pint Normal Saline
- Continue bladder irrigation
- Continue rest of RX
- Allow orally
POST OP 15/7/12 @ 1800H
- Continue bladder irrigation, stop once
completed
- IV Lasix 20mg once CBI completed
- Transfer out tonight
Indication of surgical intervention
• Acute urinary retention
• Gross hematuria
• Frequent UTI
• Vesical stone
• BPH related hydronephrosis or renal function
deterioration
• Obstruction
Conventional Surgical Therapy
• Transurethral resection of the
prostate (TURP)
• Open simple prostatectomy
TURP
“Gold Standard” of care for BPH
Uses an electrical “knife” to surgically cut and
remove excess prostate tissue
Effective in relieving symptoms and restoring
urine flow
(transurethral resection of the prostate)



TURP
Benefits
Widely available
Effective
Long lasting
Disadvantages
Greater risk of side effects
and complications
1-4 days hospital stay
1-3 days catheter
4-6 week recovery







Complication of TURP
• Immediate complication
bleeding
capsular perforation with fluid extravasation
TUR syndrome
• Late complication
urethral stricture
bladder neck contracture (BNC)
retrograde ejaculation
impotence (5-10%)
incontinence (0.1%)
Open Simple Prostatectomy
• “too large prostate” -- >100 gm
• Combined with bladder diverticulum or vesical
stone surgery
• Suprapubic or retropubic method
Minimally invasive therapy for BPH
• transurethral balloon dilatation of the prostate
(TUBDP)
• transurethral incision of the prostate (TUI)
• intraprostatic stent
• transurethral microwave thermotherapy (TUMT)
• transurethral needle ablation of the prostate (TUNA)
• transurethral electrovaporization of the prostate
(TUVP)
• photoselective vaporization of the prostate (PVP)
• Cryotherapy
• Transurethral ethanol ablation of the prostate (TEAP)
Minimally invasive therapy for BPH
• transurethral laser-induced prostatectomy (TULIP)
• visual laser ablation of the prostate (VLAP)
• contact laser prostatectomy (CLP)
• interstitial laser coagulation of the prostate (ILC)
• holmium:YAG laser resection of the prostate
(HoLRP)
• holmium:YAG laser enucleation of the prostate
(HoLEP)
• high-intensity focused ultrasound (HIFU)
coagulation
• botulinum toxin-A injection of the prostate
 Alteration in emotional
status anxiety related to
surgical procedure and
post op care.
NURSING DIAGNOSIS
NURSING DIAGNOSIS
Potential infection related
to prolonged catherization of
bladder.
NURSING DIAGNOSIS
Alteration in sleeping
pattern related to nocturia.
NURSING DIAGNOSIS
 Potential bleeding related
to surgical wound.
NURSING DIAGNOSIS
Potential infection related
to surgical incision.
NURSING DIAGNOSIS
 Alteration in ADL related to
post spinal anaesthesia.
NURSING DIAGNOSIS
 Potential infection
related to intravenous
cannula insertion.
NURSING DIAGNOSIS
 Potential infection related
to CBD catherization.
NURSING DIAGNOSIS
 Knowledge deficit related
to treatment regime and
post operative care.
Benign Prostate Hyperplasia (BPH)
Benign Prostate Hyperplasia (BPH)

Benign Prostate Hyperplasia (BPH)

  • 3.
    LEARNING OBJECTIVES State the definitionof BENIGN PROSTATE HYPERPLASIA. List the etiology of BENIGN PROSTATE HYPERPLASIA.. Identify the
  • 4.
    Cont.  State theclinical manifestation of BENIGN PROSTATE HYPERPLASIA.. Identify the complication of BENIGN PROSTATE HYPERPLASIA.. Identify the nursing intervention & appreciate the
  • 6.
    Doctor = DrN Diagnosis = BENIGN PROSTATE HYPERPLASIA with acute urinary retention
  • 7.
    Mr S wasadmitted to 5XX-1 with complaint of :  Difficulty passing urine  Nocturia & frequency  Urgency  Incomplete emptying
  • 8.
    S/B Dr N10/7 ago (2/7/12) :  US done findings – Grade 111 BPH. Put on CBDand tried to removed the CBD2/7 ago (10/7/12) but failed and problem remained same.  Came again to clinic 12/7/12 and agreed forop as suggested by DrN.
  • 10.
    ADMITTED ON 12/7/12@ 1150H  Mr S  Male  64 years old  Pensioner  Malay  Wheeled in to ward
  • 11.
    Medical history - Diabetic(20 years) - Hypertension (20 years) - IHD (2009) Surgical history - COROS (2009) in Pantai Ipoh Family medical history - Unknown Allergic - NIL
  • 12.
    Current Medication - Amlodipine -Metoprolol - Metformin - Daonil - Aspirin (On admission Dr N asked patient to stop taking)
  • 14.
    VITAL SIGNS Temp =37.5˚C Pulse = 82 bpm Resp = 21 bpm B/P = 170/80 mmHg
  • 15.
    VITAL SIGNS Weight =62 kg Pain Score = 2
  • 16.
  • 17.
  • 18.
     Frequency  Urgency Straining  Dribbling & poor stream  Nocturia  Insomnia Other ADL normal
  • 19.
    ON ARRIVAL • GXM1 pint WB • IV Sulperazone 1gm BD • Ural 1/1 TDS • Celebrex 200mg BD • Proscar 5mg Daily • BD dextrosmeter • TURP under SA on 15/7/12 • Cont own medication but stop Aspirin
  • 20.
    12/7/12 @ 2250H •Phone noted to Dr N patient put all medication mix together & cannot recognize which one is Aspirin. Dr N asked to withold all own medication.
  • 21.
    Phone ordered fromDr N : • Metformin 1gm BD • Amlodipine 7.5mg Daily • Lovastatin 10mg ON • Metoprolol 50mg BD • Daonil 7.5mg BD
  • 24.
    Understanding the prostate Walnut-shapedgland that forms part of the male reproductive system Surrounds the urethra - the tube that carries urine from the bladder out of the body  
  • 25.
    Secretes semen which carriessperm During orgasm, prostate muscles contract and propel ejaculate out of the penis Understanding the prostate  
  • 27.
    The size ofprostate enlarged microscopically since the age of 40.Half of all men over the age of 60 will develop an enlarged prostate By the time men reach their 70’s and 80’s, 80% will experience urinary symptoms But only 25% of men aged 80 will be receiving BPH treatment BPH  
  • 28.
    Peripheral zone Transition zone Urethra Whatis Benign Prostatic Hyperplasia?
  • 29.
  • 32.
    What causes BPH? BPHis part of the natural aging process, like getting gray hair or wearing glasses BPH cannot be prevented BPH can be treated   
  • 46.
  • 47.
    SURGICAL PROFILE Microscopic Examination,urine • WBC , urine 4/hpf • Bacteria, urine +
  • 48.
    CHEST X-RAY - Normal ECG -Normal sinus rhythm
  • 49.
    URINE C&S More than100000 cfu/ml of Pseudomonas aeruginosa isolated.
  • 50.
  • 51.
    ULTRASONOGRAPHY • To giveclearer view on size and shape and determine stages of BPH.
  • 52.
    International Prostate Symptom Score(IPSS) – Symptom assessment based on questionnaires developed by American Urological Association (AUA). – Contains 7 questions about severity of symptoms. – Total score : 0–7 (mild), 8–19 (moderate), 20–35 (severe)
  • 53.
    Prostate Specific Antigen(PSA) – Men with larger prostates have higher PSA levels – PSA is a predictor of disease progression and screening tool for Ca Prostate – As PSA values tend to increase with increasing PV and increasing age, PSA may be used as a prognostic marker for BPH
  • 55.
    When should BPHbe treated? BPH needs to be treated ONLY IF: Symptoms are severe enough to bother the patient and affect his quality of life Complications related to BPH 
  • 56.
     “Watchful waiting”  Medication Surgical approaches  TURP Treatment options
  • 57.
    Choosing the righttreatment Consider risks, benefits and effectiveness of each treatment Consider the outcome and lifestyle needs  
  • 59.
    “watchful waiting” For mildsymptoms. Follow up 1 to 2 times yearly Offer suggestions that help reduce symptoms Avoid caffeine and alcohol Avoid decongestants and antihistamines    
  • 60.
    Medication First line ofdefense against bothersome urinary symptoms Two major types: α blockers - relax the smooth muscle of prostate and provide a larger urethral opening (Hytrin,Doxaben,Harnalidge) 5 α reductase inhibitor - Shrink the prostate gland (Proscar, Avodart)    
  • 61.
    Benefits Convenient No loss ofwork time Minimal risk Disadvantages Drug Interactions Must be taken every day Manages the problem instead of fixing it Medication      
  • 62.
    Possible side effectsof • Impotence • Dizziness • Headaches • Fatigue • Loss of sexual drive medication     
  • 63.
  • 65.
  • 66.
    DRUGS ORDERED ON PREMED DATE ORDERED Tab Zantac 150 mg STAT 15/7/12 Tab Maxalon 10 mg STAT 15/7/12 Tab Celebrex 200 mg STAT 15/7/12
  • 67.
    POST OP 15/7/12@ 1045H - IVD 3 pint Normal Saline - Continue bladder irrigation - Continue rest of RX - Allow orally
  • 68.
    POST OP 15/7/12@ 1800H - Continue bladder irrigation, stop once completed - IV Lasix 20mg once CBI completed - Transfer out tonight
  • 70.
    Indication of surgicalintervention • Acute urinary retention • Gross hematuria • Frequent UTI • Vesical stone • BPH related hydronephrosis or renal function deterioration • Obstruction
  • 71.
    Conventional Surgical Therapy •Transurethral resection of the prostate (TURP) • Open simple prostatectomy
  • 73.
    TURP “Gold Standard” ofcare for BPH Uses an electrical “knife” to surgically cut and remove excess prostate tissue Effective in relieving symptoms and restoring urine flow (transurethral resection of the prostate)   
  • 76.
    TURP Benefits Widely available Effective Long lasting Disadvantages Greaterrisk of side effects and complications 1-4 days hospital stay 1-3 days catheter 4-6 week recovery       
  • 77.
    Complication of TURP •Immediate complication bleeding capsular perforation with fluid extravasation TUR syndrome • Late complication urethral stricture bladder neck contracture (BNC) retrograde ejaculation impotence (5-10%) incontinence (0.1%)
  • 78.
    Open Simple Prostatectomy •“too large prostate” -- >100 gm • Combined with bladder diverticulum or vesical stone surgery • Suprapubic or retropubic method
  • 79.
    Minimally invasive therapyfor BPH • transurethral balloon dilatation of the prostate (TUBDP) • transurethral incision of the prostate (TUI) • intraprostatic stent • transurethral microwave thermotherapy (TUMT) • transurethral needle ablation of the prostate (TUNA) • transurethral electrovaporization of the prostate (TUVP) • photoselective vaporization of the prostate (PVP) • Cryotherapy • Transurethral ethanol ablation of the prostate (TEAP)
  • 80.
    Minimally invasive therapyfor BPH • transurethral laser-induced prostatectomy (TULIP) • visual laser ablation of the prostate (VLAP) • contact laser prostatectomy (CLP) • interstitial laser coagulation of the prostate (ILC) • holmium:YAG laser resection of the prostate (HoLRP) • holmium:YAG laser enucleation of the prostate (HoLEP) • high-intensity focused ultrasound (HIFU) coagulation • botulinum toxin-A injection of the prostate
  • 84.
     Alteration inemotional status anxiety related to surgical procedure and post op care. NURSING DIAGNOSIS
  • 85.
    NURSING DIAGNOSIS Potential infectionrelated to prolonged catherization of bladder.
  • 86.
    NURSING DIAGNOSIS Alteration insleeping pattern related to nocturia.
  • 88.
    NURSING DIAGNOSIS  Potentialbleeding related to surgical wound.
  • 89.
    NURSING DIAGNOSIS Potential infectionrelated to surgical incision.
  • 90.
    NURSING DIAGNOSIS  Alterationin ADL related to post spinal anaesthesia.
  • 91.
    NURSING DIAGNOSIS  Potentialinfection related to intravenous cannula insertion.
  • 92.
    NURSING DIAGNOSIS  Potentialinfection related to CBD catherization.
  • 93.
    NURSING DIAGNOSIS  Knowledgedeficit related to treatment regime and post operative care.

Editor's Notes

  • #61 Relaxation of these muscle bundles lessens the resistance to outflow during urination.α
  • #62 Medications address the desire we all have to find a “cure” to fix the problem. We all like a “quick and easy” solution. They can, however, become less effective over time. Studies have shown that people tend to become less careful about following directions regarding the dose and/or frequency of taking their medication.
  • #63 Relaxation of these muscle bundles lessens the resistance to outflow during urination.