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Welcome To
Major Credit
Seminar
Welcome To
Major Credit
Seminar
Zoonotic cestode infections:
Emphasis on Neurocysticercosis and
Hydatidosis
Zoonotic cestode infections:
Emphasis on Neurocysticercosis and
Hydatidosis
Aquil Mohmad
M-5527
M.V.Sc Scholar
Diseases and infections that are naturally transmitted between
vertebrate animals and human.
(WHO)
Cestode zoonoses are emerging and spreading worldwide and are
classified as neglected zoonotic diseases .
 Asia currently has the greatest burden of cystic echinococcosis (CE)
and cysticercosis   .
( Xiaoning et al 2013)
 Sparganosis
 Hymenolepises
 Coenuriasis
 Diphyllobothriasis
 Cysticercosis
 Echinococcosis
 Bertieliasis
 Dipylidiasis
 Inermicapsifer infection
 First described by Patrick Manson
in 1882 from china
 Caused by plerocercoid larvae of
Pseudophyllidea tape worms of the
genus Spirometra
. Painful subconjunctival horseshoe
shaped swelling around the limbus in
the superior part of the bulbar
conjunctiva with surrounding chemosis
and congestion
( R. Nath  2015)
 larvae can lodge in the brain
parenchyma or spinal cord producing
seizures, headache, hemiparesis,
paralysis even death .
 Spargana
worms
.
 Theodor Bilharz (1851) first
discovered H. nana in small
intestine of an Egyptian male
 In India it is an important emerging disease of the
central nervous system second to tuberculosis
( B.B. Singh 2010 )
 It is the single most common cause of epilepsy in
the developing countries
 It is common in communities where pigs are allowed
to roam freely and the basic sanitary facilities are
lacking .
( K N Prasad et al 2008)
Areas suggested to be
highly endemic
Areas suggested to be
moderately
Areas with no or very few
cases
Areas with no available
report
Scolex
Adult Taenia
solium
Three most common sites of
infection in human (primary
host)
1. Brain (Neurocysticercosis)
2. Muscles (Cysticercosis)
3. Intestine (TaeniasisEggs
Onchosphere
hatches, penetrate
intestinal wall and
ciruculate to
musculature of pig
(intermediate host
Ingestion of raw
vegetables,fruits, salad
contaimnated with eggs
Consumption of
infected pork
Cysticerci
1
2
3
(Pratibhi, 2011)
(Monika Sharma et al , 2013 )
(Monika Sharma ;2013)
 Sheep strain (G1) is the most cosmopolitan form
and is that most commonly associated with human
infections.
 Usually one cyst present
 Cyst location
◦ 60 to 70% in liver
◦ 20 to 25% in lungs
WHO Type Cyst Morphology
Unilocular anechoic lesion with double line
containing hydatid sand.
Multiseptated rosette like honeycomb cyst
Cyst with detached membrane (waterlily sign)
Cyst with daughter cysts in solid matrix
Cyst with heterogenous hypoechoic
hyperechoic contents.
no daughter cysts
Solid and calcified wall
CE 1
CE 2
CE 3A
CE 3B
CE 4
CE 5
Thank you
Thank you

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Aquil major

  • 1. Welcome To Major Credit Seminar Welcome To Major Credit Seminar Zoonotic cestode infections: Emphasis on Neurocysticercosis and Hydatidosis Zoonotic cestode infections: Emphasis on Neurocysticercosis and Hydatidosis Aquil Mohmad M-5527 M.V.Sc Scholar
  • 2. Diseases and infections that are naturally transmitted between vertebrate animals and human. (WHO) Cestode zoonoses are emerging and spreading worldwide and are classified as neglected zoonotic diseases .  Asia currently has the greatest burden of cystic echinococcosis (CE) and cysticercosis   . ( Xiaoning et al 2013)
  • 3.  Sparganosis  Hymenolepises  Coenuriasis  Diphyllobothriasis  Cysticercosis  Echinococcosis  Bertieliasis  Dipylidiasis  Inermicapsifer infection
  • 4.  First described by Patrick Manson in 1882 from china  Caused by plerocercoid larvae of Pseudophyllidea tape worms of the genus Spirometra
  • 5. . Painful subconjunctival horseshoe shaped swelling around the limbus in the superior part of the bulbar conjunctiva with surrounding chemosis and congestion ( R. Nath  2015)  larvae can lodge in the brain parenchyma or spinal cord producing seizures, headache, hemiparesis, paralysis even death .
  • 7. .  Theodor Bilharz (1851) first discovered H. nana in small intestine of an Egyptian male
  • 8.
  • 9.
  • 10.
  • 11.  In India it is an important emerging disease of the central nervous system second to tuberculosis ( B.B. Singh 2010 )  It is the single most common cause of epilepsy in the developing countries  It is common in communities where pigs are allowed to roam freely and the basic sanitary facilities are lacking . ( K N Prasad et al 2008)
  • 12.
  • 13.
  • 14. Areas suggested to be highly endemic Areas suggested to be moderately Areas with no or very few cases Areas with no available report
  • 15. Scolex Adult Taenia solium Three most common sites of infection in human (primary host) 1. Brain (Neurocysticercosis) 2. Muscles (Cysticercosis) 3. Intestine (TaeniasisEggs Onchosphere hatches, penetrate intestinal wall and ciruculate to musculature of pig (intermediate host Ingestion of raw vegetables,fruits, salad contaimnated with eggs Consumption of infected pork Cysticerci 1 2 3
  • 16.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
  • 24.
  • 25. (Monika Sharma et al , 2013 )
  • 27.  Sheep strain (G1) is the most cosmopolitan form and is that most commonly associated with human infections.
  • 28.  Usually one cyst present  Cyst location ◦ 60 to 70% in liver ◦ 20 to 25% in lungs
  • 29.
  • 30.
  • 31. WHO Type Cyst Morphology Unilocular anechoic lesion with double line containing hydatid sand. Multiseptated rosette like honeycomb cyst Cyst with detached membrane (waterlily sign) Cyst with daughter cysts in solid matrix Cyst with heterogenous hypoechoic hyperechoic contents. no daughter cysts Solid and calcified wall CE 1 CE 2 CE 3A CE 3B CE 4 CE 5
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.

Editor's Notes

  1. Two strains - the G1 sheep strain and the G2 Tasmanian sheep strain, primarily use sheep as their intermediate host, but can also infect a variety of other species. Together with the G3 buffalo strain, the G1 and G2 strains are called Echinococcus granulosus sensu stricto. The G4 strain, which occurs only in equid intermediate hosts, does not mature in media that support the growth of the sheep strains, and does not seem to be zoonotic, is called E. equinus. G5 cattle strain has been designated Echinococcus ortleppi. It is unusual in that it regularly uses cattle, which are rarely affected by other strains, as intermediate hosts. The G6 camel strain, G7 pig strain, a poorly characterized G9 strain, and two cervid strains, G8 and G10, might comprise another species called E. canadensis. The G9 strain has been reported only from human cases in Poland, and some authors consider it to be a variant of the G7 pig strain. A lion strain has been reported from Africa. Unlike most Echinococcus species, which have canids as their primary definitive hosts, this strain mainly uses felids. It has also been called E. felidis. Some strains are still poorly characterized, and additional strains probably exist.