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TICK-BORNE PARASITIC 
INFECTIONS 
BY 
UWAMOSE, 
Martin Nelson Osaigbokan 
AUGUST , 2014
Tick-borne parasitic infections occurs throughout the world, with 
approximately 5,000 to 12,000 reported cases per year in Europe. 
The vector, tick which is a small arachnid belongs to the order 
Parasitiforms. 
It is blood sucking ectoparasite that can not survive and move from 
one stage to another without a blood meal. It is thus described an 
obligate parasite and are therefore an excellent vector for disease 
transmission. 
There are two well known parasitic infections that are tick-borne, 
they are: Babesiosis, caused by the protozoan parasites of the genus 
Babesia and Theileriosis, caused by Theileria species. 
These parasitic infections are known to infect animals such as cattle, 
causing milk reduction and growth decrease and also humans.
Risks of tick-borne infection is not uniform 
throughout the world. It occurs in tropical and 
subtropical areas of the world. They are also 
prevalent in many temperate areas such as 
northern Europe and France. The highest risk is 
in Europe where there are about 5,000 to 12,000 
cases each year (L’ Hostis and Seegers 2002).
Geographical distribution of Ticks 
Figure 1: Geographical distribution of ticks 
Source: Google images 
Hyalomma Ticks vector presence 
Serological evidence and vector presence 
5000 – 12000 cases reported per year 
12000 and more cases reported per year
BIOLOGY OF TICKS 
 Ticks are small arachnids in the order Parasitiforms. 
 Approximately 800 species have been described 
worldwide with only two well established family; 
Ixodidae (the hard ticks) and Argasidae (the Soft 
ticks). 
 They are obligate ectoparasites that feeds on the 
blood of mammals, birds and reptiles and transmits 
wide variety of pathogens. 
 They extract the blood of their host by cutting a 
hole into the host epidermis and inserting the 
hypostome. They keep the host blood from clothing 
by excreting an anticoagulant. 
 Blood is a major requirement for ticks survival and 
moving from one stage of their life to the next.
LIFE CYCLE 
The two well established of ticks undergo three primary 
stages of development: Larval, Nymph and adults. 
For Ixodid ticks, it requires three hosts and their life cycle 
takes at least one year to complete. 
The adult female ticks can lay up to 3,000 eggs on the 
ground. 
The larvae emerge, feeds on small mammals and birds 
after which they detach from their host and molt to nymph 
on the ground 
The nymph feed on larger hosts and molt to adult 
The adult attach to larger hosts, feeds very little and 
occupy the host primarily for mating.
Figure 2: Larva (A), nymph (B), adult male 
(C), adult female (D) and engorged adult 
female with eggs (E) of I. scapularis 
Source: CDC images 
Figure 3: Typical Ixodid tick 
Source: Google images
Figure 5: Typical life cycle of tick
TICK-BORNE PARASITIC DISEASES 
There are only two known tick-borne 
parasitic diseases of great economic 
importance in the world. 
Babesiosis 
Theileriosis
BABESIOSIS
Babesiosis 
CAUSES: 
Babesiosis is caused by parasitic 
protozoa of the genus Babesia. 
It is transmitted by deer tick, 
Ixodes scapularis 
Many different species of Babesia 
parasites have been found in 
animals with only a few found in 
people. 
SYMPTOMS: 
They ranges from fever, chills, 
headache, muscle pain, nausea, 
cough, sore throat, to rash in 30% 
to 40% of adults. 
TREATMENT 
Treatment is with anti-babesial 
drugs, the 
combination of atovaquone 
and azithromycin, anti-babesiosis 
vaccines. 
Tick control through insect 
repellent.
THEILERIOSIS
Theileriasis 
CAUSES: 
Theileriasis is caused by an obligate 
intracellular protozoan parasites of the 
genus Theileria. 
It is transmitted by ticks of the genus 
Hyalomma. 
The two most pathogenic and 
economically important Theileria species 
are T. parva and T. annulata. 
T. parva occurs in Eastern and Southern 
Africa while T. annulata occurs in North 
Africa, southern Europe and Asia. 
SYMPTOMS: 
Theileriosis should be suspected in tick– 
infested animals with a fever and enlarged 
lymph nodes. Others includes lacrimation, 
nasal discharge, and diarrhea. 
TREATMENT 
Treatment is with 
chemotherapeutic agents such as 
buparvaquone. 
Tick control through insect 
repellent can also be used
GENERAL DIAGNOSIS 
Tick-borne parasitic infections can be diagnosed by 
the identification of the causative agent of the 
parasites in Giemsa-stained blood smears, 
Polymerase chain reaction (PCR) test, Indirect 
fluorescent antibody (IFA) test, serology and lymph 
node needle biopsy smears especially for Theileria 
parasites (WHO 2008).
PREVENTION OF TICK-BORNE PARASITIC 
INFECTIONS 
Prevention strategies for tick-borne diseases can be divided 
into 3 general categories: Environmental, Personal, and 
Prophylactic (after a tick bite has occurred) 
 Environmental strategies involves the control of the 
population of deer and other vector and tick control 
measures. 
 Personal strategies involves avoiding grassy areas with 
shrubs that attract ticks, wearing long trousers and 
socks, applying permethrin (an insect repellent) to 
clothing. 
 Prophylactic measures include the use of vaccines.
CONCLUSION 
Scientist should put in more efforts in the study of the 
epidemiology and distribution of tick-borne parasitic 
infections as there is a growing population of ticks because 
people build homes where tick and their host inhabit. 
Awareness should therefore be made to people living such 
areas about risk of tick-borne parasitic infections. Parasite 
causing agent of the infections should be studied for better 
ways of treatment and control strategies.

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Tick-Borne Parasitic Infections: Causes, Symptoms and Prevention

  • 1. TICK-BORNE PARASITIC INFECTIONS BY UWAMOSE, Martin Nelson Osaigbokan AUGUST , 2014
  • 2. Tick-borne parasitic infections occurs throughout the world, with approximately 5,000 to 12,000 reported cases per year in Europe. The vector, tick which is a small arachnid belongs to the order Parasitiforms. It is blood sucking ectoparasite that can not survive and move from one stage to another without a blood meal. It is thus described an obligate parasite and are therefore an excellent vector for disease transmission. There are two well known parasitic infections that are tick-borne, they are: Babesiosis, caused by the protozoan parasites of the genus Babesia and Theileriosis, caused by Theileria species. These parasitic infections are known to infect animals such as cattle, causing milk reduction and growth decrease and also humans.
  • 3. Risks of tick-borne infection is not uniform throughout the world. It occurs in tropical and subtropical areas of the world. They are also prevalent in many temperate areas such as northern Europe and France. The highest risk is in Europe where there are about 5,000 to 12,000 cases each year (L’ Hostis and Seegers 2002).
  • 4. Geographical distribution of Ticks Figure 1: Geographical distribution of ticks Source: Google images Hyalomma Ticks vector presence Serological evidence and vector presence 5000 – 12000 cases reported per year 12000 and more cases reported per year
  • 5. BIOLOGY OF TICKS  Ticks are small arachnids in the order Parasitiforms.  Approximately 800 species have been described worldwide with only two well established family; Ixodidae (the hard ticks) and Argasidae (the Soft ticks).  They are obligate ectoparasites that feeds on the blood of mammals, birds and reptiles and transmits wide variety of pathogens.  They extract the blood of their host by cutting a hole into the host epidermis and inserting the hypostome. They keep the host blood from clothing by excreting an anticoagulant.  Blood is a major requirement for ticks survival and moving from one stage of their life to the next.
  • 6. LIFE CYCLE The two well established of ticks undergo three primary stages of development: Larval, Nymph and adults. For Ixodid ticks, it requires three hosts and their life cycle takes at least one year to complete. The adult female ticks can lay up to 3,000 eggs on the ground. The larvae emerge, feeds on small mammals and birds after which they detach from their host and molt to nymph on the ground The nymph feed on larger hosts and molt to adult The adult attach to larger hosts, feeds very little and occupy the host primarily for mating.
  • 7. Figure 2: Larva (A), nymph (B), adult male (C), adult female (D) and engorged adult female with eggs (E) of I. scapularis Source: CDC images Figure 3: Typical Ixodid tick Source: Google images
  • 8. Figure 5: Typical life cycle of tick
  • 9. TICK-BORNE PARASITIC DISEASES There are only two known tick-borne parasitic diseases of great economic importance in the world. Babesiosis Theileriosis
  • 11. Babesiosis CAUSES: Babesiosis is caused by parasitic protozoa of the genus Babesia. It is transmitted by deer tick, Ixodes scapularis Many different species of Babesia parasites have been found in animals with only a few found in people. SYMPTOMS: They ranges from fever, chills, headache, muscle pain, nausea, cough, sore throat, to rash in 30% to 40% of adults. TREATMENT Treatment is with anti-babesial drugs, the combination of atovaquone and azithromycin, anti-babesiosis vaccines. Tick control through insect repellent.
  • 13. Theileriasis CAUSES: Theileriasis is caused by an obligate intracellular protozoan parasites of the genus Theileria. It is transmitted by ticks of the genus Hyalomma. The two most pathogenic and economically important Theileria species are T. parva and T. annulata. T. parva occurs in Eastern and Southern Africa while T. annulata occurs in North Africa, southern Europe and Asia. SYMPTOMS: Theileriosis should be suspected in tick– infested animals with a fever and enlarged lymph nodes. Others includes lacrimation, nasal discharge, and diarrhea. TREATMENT Treatment is with chemotherapeutic agents such as buparvaquone. Tick control through insect repellent can also be used
  • 14. GENERAL DIAGNOSIS Tick-borne parasitic infections can be diagnosed by the identification of the causative agent of the parasites in Giemsa-stained blood smears, Polymerase chain reaction (PCR) test, Indirect fluorescent antibody (IFA) test, serology and lymph node needle biopsy smears especially for Theileria parasites (WHO 2008).
  • 15. PREVENTION OF TICK-BORNE PARASITIC INFECTIONS Prevention strategies for tick-borne diseases can be divided into 3 general categories: Environmental, Personal, and Prophylactic (after a tick bite has occurred)  Environmental strategies involves the control of the population of deer and other vector and tick control measures.  Personal strategies involves avoiding grassy areas with shrubs that attract ticks, wearing long trousers and socks, applying permethrin (an insect repellent) to clothing.  Prophylactic measures include the use of vaccines.
  • 16. CONCLUSION Scientist should put in more efforts in the study of the epidemiology and distribution of tick-borne parasitic infections as there is a growing population of ticks because people build homes where tick and their host inhabit. Awareness should therefore be made to people living such areas about risk of tick-borne parasitic infections. Parasite causing agent of the infections should be studied for better ways of treatment and control strategies.