This document discusses drugs used in the urinary system. It focuses on antidiuretics, which reduce urine volume. The main antidiuretic discussed is vasopressin, also called antidiuretic hormone (ADH), which is produced in the brain and tells the kidneys to conserve water. It is used to treat conditions like diabetes insipidus and bedwetting. Nurses must monitor patients taking antidiuretics for electrolyte imbalances, vital signs, signs of allergic reactions, and stop the medication if hypertension develops.

1. Drugs used on Urinary
System
Presented By:
Ms. Sayali Dilip Powar
(Master of Pharmacy )
5/12/2020
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2. Content
• Diuretics
• Antidiuretics
• Urinary Antiseptics
• Cholinergics & Anticholinergics
• Acidifiers
• Alkalanizers.
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Composition
 Action
 Dosage
 Route
 Indications,
Contraindications
 Drug Interactions
 Side Effects,
Adverse, Effects,
Toxicity
 Role Of Nurse

3. Content
ANTIDIURETICS
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Composition
 Action
 Dosage
 Route
 Indications,
Contraindications
 Drug Interactions
 Side Effects,
Adverse, Effects,
Toxicity
 Role Of Nurse

4. Antidiuretics
Antidiuretics reduce urine volume, particularly
in diabetes insipidus
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6. ADH
• .
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ADH is also called arginine vasopressin. It's a hormone made by the
hypothalamus in the brain and stored in the posterior pituitary gland. It
tells your kidneys how much water to conserve. ADH constantly
regulates and balances the amount of water in your blood

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8. CLASSIFICATION
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Antidiuretic
Hormoes and its
analogues
• Vasopressin
• Desmopressin
Natriuretics
• Thiazides
• Amiloride
Miscellaneous
• Carbamazepine
• Chlorpropamide

9. MECHANISM OF ACTION
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Reduces urine flow by acting
reabsorption of water by
kidney tubules

10. INDICATION AND USE
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1. Diabetes insipidus.
2. Primary bed wetting
3. Nocturia associated with multiple sclerosis

11. EXAMPLE
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12. CONTRAINDICATION
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Hypersensitivity, impaired renal function, with
ongoing diuretic treatment, Caution in CV
disease, edema, hypertension, cystic fibrosis,
fluid and electrolyte imbalance, pregnancy
and lactation.

13. ADVERSE EFFECT
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Nasal irritation, Rhinitis, Abdominal cramps,
Urge defecate, fluid retention, congestion,
Ulceration, nausea, pallor, Backache in
females (due to uterine contraction)

14. NURSING RESPONSIBILITIES
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• Monitor electrolyte imbalance.
• Monitor vital signs and B.P. regularly.
• Observe for sign of hypersensitivity
reactions.
• Monitor laboratory values.
• Stop medication if hypertension exists.

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