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Anesthesia Management 
for Maternal with Heart Diseases 
Purwoko 
Dept. of Anesthesiology and Intensive Therapy 
Dr. Moewardi General Hospital / Sebelas Maret Univ 
Surakarta 
2014
Introduction 
 Latest management for maternal with heart 
disease requiring surgery. 
 Techniques of regional anesthesia in patients 
with heart disease need little adjustment. 
 Monitoring of fluid and several heart function.
 The prevalence of heart disease in 
pregnancy is 0.4 - 1% 
 High risk maternal requires an 
understanding of the impact of pregnancy 
and heart lesions on hemodynamic 
response 
 Objective : To discuss anesthesia 
management for maternal with common 
heart lesions which requires non cardiac 
surgery.
Physiological changes in pregnancy 
• Stroke volume ↑↑, Heart rate ↑↑. 
• Cardiac output ↑↑ 
• Sistemic vascular resistance ↓ ± 20% 
• Blood flow to uterus ↑↑ 700-900 ml / hour 
(increasing heart load) 
• - Healthy heart no problem 
- Abnormal heart  problem
1. Congenital Heart Disease 
 Patent ductus arteriosus (PDA), Atrial 
Septal Defect (ASD) and Ventricular Septal 
Defect (VSD) are common congenital heart 
diseases 
 Increased cardiovascular volume during 
pregnancy →increasing atrial volume that 
leads to enlargement of both atria and 
susceptibility of supraventriculare 
dysrhythmias
 Actions performed on the CHD patients : 
1. Prevention of air bubbles into the intravenous 
access. 
2. Epidural anesthesia is better using NaCl, slow 
onset of epidural analgesia 
3. Oxygen supplementation 
4. Antibiotic prophylaxis is recommended.
Tetralogy of Fallot (TOF) 
 Minimizing hemodynamic changes that 
leads to increased R to L shunt. 
 It is important to prevent decreased in SVR, 
venous return or myocardial depression 
 Both GA or RA techniques can be used.
• For GA, induction agents chosen are 
those that cause the most minimal 
hemodynamic changes, for examples 
narcotics and etomidate. 
• Regional anesthesia techniques can be 
used with special attention. 
• Single Shot spinal anesthesia should be 
avoided. 
• Slow induction of epidural anesthesia is 
recommended
Eisenmenger Syndrome 
 Abnormalities : pulmonary hypertension, 
right-to-left shunting produces arterial 
hypoxemia. 
 Clinical manifestations include dyspnoea, 
clubbing, polycythemia, peripheral edema 
and cyanosis. 
 Avoid decreased of SVR.
 RA or GA may be used if only there are no 
contraindications . RA can be done using 
epidural dose titration. 
 Oxygen should be given 
 Blood loss should be replaced with colloid, 
crystalloid or blood components. 
 Invasive Monitoring should be done such as 
arterial Line and CVP 
 Ampycillin and Gentamicin should be given as 
prophylaxis drugs against infective 
endocarditis and repeated every 8 hours after 
the initial dose.
Valvular Heart Diseases 
1. Mitral stenosis 
 Maintain heart rate, venous return and 
SVR remained low (slow) 
 Avoid aorto caval compression, 
aggressive treatment of atrial fibrillation, 
maintaining sinus rhythm. 
 prevent pain, hypoxemia, hypercarbia 
and acidosis ↑↑ SVR. 
 Both RA or GA can be used.
 Epidural anesthesia is an option 
 Vasopressors: low dose of phenylephrine. 
 GA also provide stable hemodynamics, 
 Etomidate is best used as an induction 
agent. 
 Beta blockers such as esmolol and 
moderate dose of opioids should be 
administered before induction
2. Mitral regurgitation 
• Pregnancy will induce a state of hyper 
coagulation and systemic embolism. 
• Epidural anesthesia can prevent an increase in 
SVR, and prevent pulmonary congestion. 
• Invasive blood pressure monitoring 
• Antibiotics profilaxis is recommended 
• GA : Ketamin and Pancuronium
• The main consideration is maintaining 
slight increase in heart rate to prevent an 
increase in SVR and central blood volume. 
• Prevent hypoxemia, hypercarbia, acidosis 
that will lead to an increase in PVR. 
• Avoiding Aortocaval compression and 
myocardial depression.
3. Aorta Stenosis 
 In aorta stenosis, transvascular gradient will 
progressively increased during pregnancy, this 
is due to an increase in blood volume and 
decrease in SVR. 
 Avoid tachycardia and bradycardia, maintain 
intravascular volume and "venous return", avoid 
aortocaval compression and myocardial 
depression, maintain heart rate as the normal 
condition because decrease in heart rate will 
decrease cardiac output
 GA: combination of etomidate and mid-dose 
opioids with succinylcholine for 
"Rapid Sequence intubation". 
 Myocardial depression due to volatile 
anesthetic agents should be avoided 
 Pulmonary artery catheter monitoring is 
controversial, CVP monitoring is needed 
and must be maintained at high normal 
level
4. Aorta Insufficiency 
 Pathophysiology that occurs due to the "volume overload" on 
the LV, with hypertrophy and dilatation and increased LVEDV, 
decreased ejection fraction (EF) and signs and symptoms of 
edema pumonal. 
 Minimalizing pain is an attempt to prevent release of 
catecholamines , which may increase SVR 
 Avoid bradycardia because it can lead to an increase in 
regurgitant flow.
• Epidural anesthesia is 
preferable/recommended 
• Induction agent using etomidate, 
endotracheal intubation using 
suxamethonium 
• Remifentanyl for analgesia
5. Prosthetic Valves 
 The high risk of fetal and maternal 
complications 
 The use of anticoagulant therapy is contra 
indication for regional anesthesia. 
 GA: the use of an additional monitoring tool 
such as CVP, PA catheter and A-Line
Peripartum Cardiomyopathy (PPCM) 
 Heart failure can occurs in the 3rd trimester, EF less 
than 45% and diastolic dimensions greater than 
2.72cm / m2 
 Avoiding myocardial depression and attention to fluid 
management with the use of diuretics and 
vasodilators, as well as keeping the heart rate within 
the normal range with sinus rhythm. 
 Titration slowly CSA / CEA 
 GA: monitoring invasive, PA Line, A Line 
 Narcotics for the induction and maintenance of 
anesthesia
Maternal arrhythmias during pregnancy 
Cathecolamine Sensitive Ventricular Tachycardia (VT) 
 Often due to the VT re-entry (ca) 
 Patients with a history of VT are required to continue the 
anti-arrhythmia medication during pregnancy. 
 CSE drug delivery slowly (slow incremental)
Congenital Heart Block and Bradyarrhytmia 
 The use of pacemaker; QT interval lengthening or 
if there is enlargement of the left atrium. 
 Access CVC and "trans Venous Pacing wires 
should be prepared in addition to the patient 
during the surgery 
 Epidural analgesia is recommended for surgery 
and postoperative pain.
Maternal postoperative period in 
heart disease 
 Patients with less - severe cardiac dysfunction that undergo 
surgery should be monitored in Intensive Care Unit (ICU) 
 The first 24-72 hours of fluid displacement will appear 
significantly. 
 Adequate postoperative analgesia should be provided in the 
form of "continuous epidural analgesia" or "patient controlled 
IV analgesia”. 
 Provision of early ambulation to minimize the occurrence of 
"deep vein thrombosis and paradoxical emboli"
"Outcome" of fetal and maternal heart disease 
requiring surgery 
• Mortality that is less than 1% have been 
reported in patients with NYHA Class I and 
II, whereas in NYHA Class III and IV are 
about 5-15%.
Conclusions 
 Cardiologist, obstetrician and anestesiologist should 
cooperate to each other 
 The advantage of regional anesthesia is patients can 
communicate if symptoms occur 
 If palpitations, chest pain and shortness of breath 
happened, immediate action should be performed 
 RA should be given using lower dose of local 
anesthetics opioids and slow induction 
 GA : standard technique “rapid sequence induction”
THANK YOU

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anesthesia management for maternal with heart disease

  • 1. Anesthesia Management for Maternal with Heart Diseases Purwoko Dept. of Anesthesiology and Intensive Therapy Dr. Moewardi General Hospital / Sebelas Maret Univ Surakarta 2014
  • 2. Introduction  Latest management for maternal with heart disease requiring surgery.  Techniques of regional anesthesia in patients with heart disease need little adjustment.  Monitoring of fluid and several heart function.
  • 3.  The prevalence of heart disease in pregnancy is 0.4 - 1%  High risk maternal requires an understanding of the impact of pregnancy and heart lesions on hemodynamic response  Objective : To discuss anesthesia management for maternal with common heart lesions which requires non cardiac surgery.
  • 4. Physiological changes in pregnancy • Stroke volume ↑↑, Heart rate ↑↑. • Cardiac output ↑↑ • Sistemic vascular resistance ↓ ± 20% • Blood flow to uterus ↑↑ 700-900 ml / hour (increasing heart load) • - Healthy heart no problem - Abnormal heart  problem
  • 5. 1. Congenital Heart Disease  Patent ductus arteriosus (PDA), Atrial Septal Defect (ASD) and Ventricular Septal Defect (VSD) are common congenital heart diseases  Increased cardiovascular volume during pregnancy →increasing atrial volume that leads to enlargement of both atria and susceptibility of supraventriculare dysrhythmias
  • 6.  Actions performed on the CHD patients : 1. Prevention of air bubbles into the intravenous access. 2. Epidural anesthesia is better using NaCl, slow onset of epidural analgesia 3. Oxygen supplementation 4. Antibiotic prophylaxis is recommended.
  • 7. Tetralogy of Fallot (TOF)  Minimizing hemodynamic changes that leads to increased R to L shunt.  It is important to prevent decreased in SVR, venous return or myocardial depression  Both GA or RA techniques can be used.
  • 8. • For GA, induction agents chosen are those that cause the most minimal hemodynamic changes, for examples narcotics and etomidate. • Regional anesthesia techniques can be used with special attention. • Single Shot spinal anesthesia should be avoided. • Slow induction of epidural anesthesia is recommended
  • 9. Eisenmenger Syndrome  Abnormalities : pulmonary hypertension, right-to-left shunting produces arterial hypoxemia.  Clinical manifestations include dyspnoea, clubbing, polycythemia, peripheral edema and cyanosis.  Avoid decreased of SVR.
  • 10.  RA or GA may be used if only there are no contraindications . RA can be done using epidural dose titration.  Oxygen should be given  Blood loss should be replaced with colloid, crystalloid or blood components.  Invasive Monitoring should be done such as arterial Line and CVP  Ampycillin and Gentamicin should be given as prophylaxis drugs against infective endocarditis and repeated every 8 hours after the initial dose.
  • 11. Valvular Heart Diseases 1. Mitral stenosis  Maintain heart rate, venous return and SVR remained low (slow)  Avoid aorto caval compression, aggressive treatment of atrial fibrillation, maintaining sinus rhythm.  prevent pain, hypoxemia, hypercarbia and acidosis ↑↑ SVR.  Both RA or GA can be used.
  • 12.  Epidural anesthesia is an option  Vasopressors: low dose of phenylephrine.  GA also provide stable hemodynamics,  Etomidate is best used as an induction agent.  Beta blockers such as esmolol and moderate dose of opioids should be administered before induction
  • 13. 2. Mitral regurgitation • Pregnancy will induce a state of hyper coagulation and systemic embolism. • Epidural anesthesia can prevent an increase in SVR, and prevent pulmonary congestion. • Invasive blood pressure monitoring • Antibiotics profilaxis is recommended • GA : Ketamin and Pancuronium
  • 14. • The main consideration is maintaining slight increase in heart rate to prevent an increase in SVR and central blood volume. • Prevent hypoxemia, hypercarbia, acidosis that will lead to an increase in PVR. • Avoiding Aortocaval compression and myocardial depression.
  • 15. 3. Aorta Stenosis  In aorta stenosis, transvascular gradient will progressively increased during pregnancy, this is due to an increase in blood volume and decrease in SVR.  Avoid tachycardia and bradycardia, maintain intravascular volume and "venous return", avoid aortocaval compression and myocardial depression, maintain heart rate as the normal condition because decrease in heart rate will decrease cardiac output
  • 16.  GA: combination of etomidate and mid-dose opioids with succinylcholine for "Rapid Sequence intubation".  Myocardial depression due to volatile anesthetic agents should be avoided  Pulmonary artery catheter monitoring is controversial, CVP monitoring is needed and must be maintained at high normal level
  • 17. 4. Aorta Insufficiency  Pathophysiology that occurs due to the "volume overload" on the LV, with hypertrophy and dilatation and increased LVEDV, decreased ejection fraction (EF) and signs and symptoms of edema pumonal.  Minimalizing pain is an attempt to prevent release of catecholamines , which may increase SVR  Avoid bradycardia because it can lead to an increase in regurgitant flow.
  • 18. • Epidural anesthesia is preferable/recommended • Induction agent using etomidate, endotracheal intubation using suxamethonium • Remifentanyl for analgesia
  • 19. 5. Prosthetic Valves  The high risk of fetal and maternal complications  The use of anticoagulant therapy is contra indication for regional anesthesia.  GA: the use of an additional monitoring tool such as CVP, PA catheter and A-Line
  • 20. Peripartum Cardiomyopathy (PPCM)  Heart failure can occurs in the 3rd trimester, EF less than 45% and diastolic dimensions greater than 2.72cm / m2  Avoiding myocardial depression and attention to fluid management with the use of diuretics and vasodilators, as well as keeping the heart rate within the normal range with sinus rhythm.  Titration slowly CSA / CEA  GA: monitoring invasive, PA Line, A Line  Narcotics for the induction and maintenance of anesthesia
  • 21. Maternal arrhythmias during pregnancy Cathecolamine Sensitive Ventricular Tachycardia (VT)  Often due to the VT re-entry (ca)  Patients with a history of VT are required to continue the anti-arrhythmia medication during pregnancy.  CSE drug delivery slowly (slow incremental)
  • 22. Congenital Heart Block and Bradyarrhytmia  The use of pacemaker; QT interval lengthening or if there is enlargement of the left atrium.  Access CVC and "trans Venous Pacing wires should be prepared in addition to the patient during the surgery  Epidural analgesia is recommended for surgery and postoperative pain.
  • 23. Maternal postoperative period in heart disease  Patients with less - severe cardiac dysfunction that undergo surgery should be monitored in Intensive Care Unit (ICU)  The first 24-72 hours of fluid displacement will appear significantly.  Adequate postoperative analgesia should be provided in the form of "continuous epidural analgesia" or "patient controlled IV analgesia”.  Provision of early ambulation to minimize the occurrence of "deep vein thrombosis and paradoxical emboli"
  • 24. "Outcome" of fetal and maternal heart disease requiring surgery • Mortality that is less than 1% have been reported in patients with NYHA Class I and II, whereas in NYHA Class III and IV are about 5-15%.
  • 25. Conclusions  Cardiologist, obstetrician and anestesiologist should cooperate to each other  The advantage of regional anesthesia is patients can communicate if symptoms occur  If palpitations, chest pain and shortness of breath happened, immediate action should be performed  RA should be given using lower dose of local anesthetics opioids and slow induction  GA : standard technique “rapid sequence induction”