Muscles of mastication are the group of muscles that help in movement of the mandible as during chewing and speech. We need to study these muscles as they control the opening & closing the mouth & their role in the equilibrium created within the mouth. They also play a role in the configuration of face.
this presentation describes the detail anatomy of Temporo-mandibular joint with respect to its articulating surfaces, ligaments, muscles and blood and nerve supply.
Muscles of mastication are the group of muscles that help in movement of the mandible as during chewing and speech. We need to study these muscles as they control the opening & closing the mouth & their role in the equilibrium created within the mouth. They also play a role in the configuration of face.
this presentation describes the detail anatomy of Temporo-mandibular joint with respect to its articulating surfaces, ligaments, muscles and blood and nerve supply.
Amelogenesis is the formation of enamel. During amelogenesis, the ameloblast (enamel-forming cells) undergo various stages i.e the life cycle of ameloblast.
For more content check out my blog: www.rkharitha.wordpress.com "a little about everything dental"
It contains following subheadings:
-maxilla and mandible anatomy
-TMJ(Temporo mandibular joint)
-Muscles of mastication
By:
Dr. Syed Irfan Qadeer
Prof. and HOD Department of Anatomy
SPIDMS,Lucknow
Amelogenesis is the formation of enamel. During amelogenesis, the ameloblast (enamel-forming cells) undergo various stages i.e the life cycle of ameloblast.
For more content check out my blog: www.rkharitha.wordpress.com "a little about everything dental"
It contains following subheadings:
-maxilla and mandible anatomy
-TMJ(Temporo mandibular joint)
-Muscles of mastication
By:
Dr. Syed Irfan Qadeer
Prof. and HOD Department of Anatomy
SPIDMS,Lucknow
Detailed discussion on surgical anatomy of salivary glands with special focus on major glands. Relationship of facial nerve and its branhes to parotid gland is also discussed. Complications are also discussed. Surgical approaches are also discussed.
Hi readers,
I hope this slide show will help you for quick revision.
By viewing this slide your able to know about landmarks in mandible, functions of each part,why they are called supporting, limiting, and relief areas.how they compensate with denture ,how do we take care during impression ,where we apply pressure and ,the places which should be relieved.till where we extend denture.I hope this slides will help you more for better understanding.
##thank u ###keep learning###
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
2. INTRODUCTION
• The mandible- largest and strongest bone of the face.
• Horseshoe shaped body which lodges the teeth
• Pair of Rami
3. BODY OF THE MANDIBLE
• Outer and inner surfaces and upper and lower borders
Outer surface
• Symphysis menti
• Mental protuberance
• Mental foramen
• Oblique line
• Incisive fossa
5. RAMUS
• Quadrilateral in shape
• Lateral and medial surfaces
• Anterior, posterior, upper and lower borders
• Coronoid and condylar processes
6. • Lateral surface- relatively featureless, bears the oblique
ridge in lower half
• Medial surface- Mandibular foramen, mandibular canal
• Lingula
• Mylohyoid groove
• Upper border- thin, mandibular notch
• Lower border- base, continuous with posterior border at
the angle
• Coronoid process
• Condylar process- fibrocartilage- TMJ, neck, pterygoid
fovea
7. ATTACHMENTS AND RELATIONS
• Buccinator, depressor labii inferioris, depressor anguli oris
• Incisive fossa-Mentalis, mentalis slips of orbicularis oris
• Deep cervical fascia
• Platysma
• Masseter
• Parotid gland
8. • Mylohyoid muscle
• Superior constrictor
• Pterygomandibular raphe
• Genioglossus, geniohyoid
• Anterior belly of digastric
• Sphenomandibular ligament
• Medial pterygoid
• Temporalis
• Lateral pterygoid
• Latreal part of the neck- Lateral ligament of temporomandibular joint
9. FORAMINA, NERVES AND VESSELS
• Mental foramen- mental nerves and vessels
• Mandibular foramen and canal- IAN and vessels
• Mylohyoid groove- mylohyoid nerve and vessels
• Lingual nerve
• Maxillary artery
• Mandibular notch- masseteric nerves and vessels
• Auriculotemporal nerve and superficial temporal artery- neck
• Facial artery
• Accessory foramina
10. ALVEOLAR PROCESS
• That portion of maxilla and mandible that forms
and supports the tooth socket.
• Parts-
• 1. external plate of cortical bone
• 2. alveolar bone proper (lamina dura) –
cribriform plate
• 3. cancellous trabeculae
11. OSSIFICATION
• Mandible is the second bone next to clavicle to ossify in the body. Its greater part ossifies in
membrane.
• The parts ossifying in cartilage- incisive part below the incisors, coronoid and condylar
process, and upper half of the ramus above the level of mandibular foramen
• Each half of the mandible ossifies from only one centre which appears at about the 6th week
of intrauterine life in the mesenchymal sheath of meckels cartilage near the future mental
foramen
• At birth mandible consists of 2 halves connected at the symphysis menti by fibrous tissue.
Bony union takes place during the first year of life.
12. AGE CHANGES IN MANDIBLE
Infants and children-
• 2 halves fuse during the first year of life
• At birth the mental foramen opens below the sockets for the two deciduous molar teeth near
the lower border.
• Mandibular canal runs near the lower border. The foramen and canal gradually shifts
upwards
• Angle- obtuse 140 degrees or more
• The coronoid process is large and projects upward above the level of the condyle.
13. In adults
• The mental foramen opens midway between the upper and
lower borders
• Mandibular canal runs parallel to the mylohyoid line
• Angle- 110-120 degrees
In old age
• Height of the bone is markedly reduced
• Mental foramen and the mandibular canal are close to the
alveolar border
• Angle- obtuse 140 degrees
14. MYLOHYOID MUSCLE
• Severely resorbed ridge- origin of mylohyoid muscle approximates the crest
of the ridge, especially in the posterior mandible. In these cases, surgical
manipulation of the crest may injure the muscle.
• A mandibular periosteal reflection for sub periosteal implant often reflects
this muscle to the second molar region. The sub structure of the implant
then has a permucosal site in the 1st molar region and a lingual primary strut
above and below the muscle.
• Surgical manipulation of the tissue of the floor of the mouth- edematous
swelling of the sub lingual and the sub mandibular space, echymossis can
occur sub-cutaneously or sub-mucosally.
• In some cases- cellulitis or abcess sub-lingually or sub-mandibularly
15. GENIOGLOSSUS
• Origin- superior genial tubercle
• Main protruder of the tongue, branch of hypoglossal nerve
• During elevation of lingual mucosa and before impression making for a
sub periosteal implant, one should be aware of the origin to avoid
causing injury.
• A portion of the muscle can be reflected from the tubercle but should
not be completely detached from the tubercle because it may result in
retrusion of the tongue and possible airway obstruction.
16. MEDIAL PTERYGOID
• Medial pterygoid bounds the pterygo mandibular space
medially. This space is entered when an IANB is admistered
• Infection of this space is dangerous because of its proximity
to parapharyngeal space and the potential spread of
infection to mediastinum.
• Mandibular nerve
17. TEMPORALIS
• Origin from temporal fossa and inserts into the coronoid process
and anterior border of the ramus
• Retromolar triangle- surgical exposure of mandibular ramus
medially would involve this triangle which may lead to transaction
and post op pain.
• Incisions placed on the anterior ascending ramus should be
placed below the insertion of the two tendons of the muscle.
• Retractor and elevator, mandibular nerve
18. MENTALIS
• Origin- mental tubercles, insertion- skin of the chin
• Complete reflection of the mentalis muscle for the purpose of extension of a sub periosteal
implant may result in witch’s chin due to failure of muscle re attachment.
• If the muscle is completely detached to expose the symphysis, then an elastic bandage is
applied externally to the chin for 4 days to help in re attachment.
• Facial nerve
19. MASSETER
• This muscle can easily be deflected during surgery to expose bone
for ramus extension needed for lateral support for a sub periosteal
implant.
• The space between the masseteric fascia and the muscle is a
potential surgical space known as the masseteric space into which
infection may spread causing myositis and trismus.
• Mandibular nerve
20. INFERIOR ALVEOLAR NERVE
• In an excessively resorbed ridge, mental foramen
with its contents can be found on the crest of the
ridge. While making incisions or reflection of mucosa
in this region, care should be taken to avoid injury to
these vital structures.
• Knowledge of the position of the mandibular canal in
vertical and buccolingual dimensions is of paramount
importance during site prep for implants
21. LINGUAL NERVE
• Because this nerve lies just medial to the retromolar pad, incisions in this
region should remain lateral to the pad.
• And the mucosal reflection should be done with the periosteal elevator in
constant contact with bone to prevent injury to the nerve.
• Improper reflection of a lingual mucoperiosteal flap may injure the lingual
nerve and produce ipsilateral paraesthesia or anaesthesia, loss of taste, and
reduction of salivary secretion.
22. LONG BUCCAL NERVE
• The nerve courses between the 2 heads of lateral pterygoid and precedes medial to the medial
tendon of the temporalis to gain access to the buccinator.
• The nerve supplies the skin of the cheek and runs down to the level of the external oblique ridge,
penetrates the buccinators and spread its branches under the cheek mucosa alveolar mucosa and
attached gingiva opp molar teeth
• An implantologist planning to access the ramus for the purpose of excising block graft should be
aware of the buccal nerve and avoid injuring it.
• In addition, surgical manipulation in this area (insertion of sub periosteal implant) may injure this
nerve
23. BLOOD SUPPLY OF THE MANDIBLE
• Major artery- inferior alveolar artery
• Incisive branch is often severed during the harvest of a mono cortical symphyseal block of
bone for grafting resorbed ridges
Changes with age
• Reversal of flow
• Atherosclerotic changes- tortuous and narrow
• Arteries that supply blood after the interruption – mental artery, mandibular branch of sub
lingual artery, facial artery
• These anastomoses are critical in procedures with mucoperiosteal flaps.
24. CONCLUSION
• The surgical anatomy of the maxilla and mandible provide the foundation required to safely
insert dental implants.
• The anatomy is also a requisite to the understanding of complications that may inadvertently
occur during surgery such as injury to blood vessels and nerves
• This information also provides the operator the confidence needed to deal with these
complications.
25. REFERENCES
• Bd Chaurasia’s Human Anatomy 2nd edition
• Carranza’s clinical periodontology 10th edition
• Contemporary implant dentistry, Carl E Misch, 3rd edition
Editor's Notes
Superior to the genial tubercles most mandibles display a lingual foramen which opens into a canal. It contains a branch of lingual artery.
Accessory foramina are numerous and transmit auxillay nerves to the teeth