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S Y N A P S E
 
DEFINITION ,[object Object],[object Object],[object Object]
HISTORY Charles Sherrington  Ramón y Cajal
ELECTRICAL & CHEMICAL SYNAPSE ,[object Object]
 
NERVE-MUSCLE SYNAPSE ,[object Object],[object Object],[object Object]
 
SYNAPTIC ANATOMY   ,[object Object],[object Object]
 
Electrical vs. Chemical Transmission ,[object Object],[object Object]
Electrical vs. Chemical Transmission ,[object Object],[object Object],[object Object],[object Object]
Electrical Transmission   ,[object Object]
Electrical Transmission   ,[object Object]
CHEMICAL TRANSMISSION ,[object Object],[object Object],[object Object],[object Object]
Steps in Transmission at a Chemical Synapse ,[object Object],[object Object],[object Object],[object Object]
Steps in Transmission at a Chemical Synapse ,[object Object],[object Object],[object Object],[object Object]
Transmission at a Chemical Synapse ,[object Object],[object Object],[object Object]
Transmission at a Chemical Synapse ,[object Object],[object Object],[object Object]
EXCITATORY & INHIBITORY SYNAPSES ,[object Object],[object Object]
UNIDIRECTIONAL TRANSMISSION   ,[object Object],[object Object]
No Yes 6. Influenced by membrane potential Yes, but over shorter time Yes 5. Summation Yes Yes 4. Inhibition No Yes 3. Delay No Yes 2. Amplification Sometimes, usually not Always 1. Rectification Electrical synapses Chemical synapses Property PROPERTIES OF SINGLE CHEMICAL AND ELECTRICAL SYNAPSES
NEUROTRANSMITTERS ,[object Object],[object Object],[object Object],[object Object],[object Object]
AXOPLASMIC TRANSPORT OF ENZYMES ,[object Object],[object Object],[object Object]
NEUROMUSCULAR JUNCTION: RELEASE OF ACETYLCHOLINE ,[object Object],[object Object]
NEUROMUSCULAR JUNCTION: RELEASE OF ACETYLCHOLINE ,[object Object],[object Object],[object Object]
 
NEUROMUSCULAR JUNCTION: RELEASE OF ACETYLCHOLINE ,[object Object],[object Object],[object Object]
POSTSYNAPTIC EXCITATORY EVENTS ,[object Object],[object Object]
POSTSYNAPTIC EXCITATORY EVENTS ,[object Object],[object Object],[object Object],[object Object]
POSTSYNAPTIC EXCITATORY EVENTS ,[object Object],[object Object],[object Object],[object Object]
SINGLE AP IN THE MOTOR NERVE – SINGLE AP IN THE MUSCLE ,[object Object],[object Object],[object Object]
TERMINATION OF TRANSMITTER   ,[object Object],[object Object]
ACTION BY ACETYLCHOLINESTERASE   ,[object Object],[object Object]
EXTRACELLULAR CALCIUM ,[object Object],[object Object],[object Object]
EXTRACELLULAR MAGNESIUM ,[object Object],[object Object],[object Object],[object Object]
BOTULINUS TOXIN   ,[object Object],[object Object],[object Object]
Black Widow Spider Toxin   ,[object Object],[object Object],[object Object]
Postsynaptic AChReceptors: Competitive Blockers   ,[object Object],[object Object],[object Object]
Postsynaptic AChReceptors: Depolarizing Blockers ,[object Object],[object Object],[object Object],[object Object]
Factors Affecting Neuromuscular Transmission: Myasthenia Gravis ,[object Object],[object Object],[object Object],[object Object]
MYASTHENIA GRAVIS ,[object Object],[object Object],[object Object]
MYASTHENIA GRAVIS ,[object Object],[object Object],[object Object]
CONCLUSION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BRITANNICA ENCYCLOHEDIA: SYNAPSE   ,[object Object]
I thank all of you for your patience!

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3. synapse 08-09

  • 1. S Y N A P S E
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  • 22. No Yes 6. Influenced by membrane potential Yes, but over shorter time Yes 5. Summation Yes Yes 4. Inhibition No Yes 3. Delay No Yes 2. Amplification Sometimes, usually not Always 1. Rectification Electrical synapses Chemical synapses Property PROPERTIES OF SINGLE CHEMICAL AND ELECTRICAL SYNAPSES
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  • 46. I thank all of you for your patience!