Genetic variation between organisms of the same species is caused by mutations in genes. Mutations can occur in germ cells, which are passed down to offspring, or in somatic cells. Mutations may be harmful, neutral, or beneficial to an organism's survival and ability to reproduce. Harmful mutations reduce reproduction chances and are less likely to be passed on. Neutral mutations may be passed on over generations without effect. Beneficial mutations increase survival and reproduction, proliferating in future generations.