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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 882
Detection of Breast Asymmetry by Active Contour
Segmentation Technique
Jincy Denny1, Mrs.Sobha T2
1M-Tech Student, Adi Shankara Institute of Engineering and Technology, Kalady, Kerala, India
2Professor, Dept. of Computer Science and Engineering, Adi Shankara College, Kalady, Kerala, India
---------------------------------------------------------------------***----------------------------------------------------------------------
Abstract - A method for the detection of the breast boundary
in mammograms is provided. The approach started with
adjustment of the original image's contrast. A
binary technique was then applied to the image, and an
approximate contour of the breast was found using the active
contour algorithm in Matlab. Finally, the identification of the
true breast boundary was carried out using the estimated
contour as the input to a specifically tailored active contour
model algorithm for this purpose.
Key Words: Active contour algorithm, Matlab, Breast
Asymmetry, contour segmentation, segmentation
techniques
1. INTRODUCTION
Breast cancer among women around the world is the most
common type of cancer. Recent statistics suggest thatbreast
cancer affects one in ten women in Europe and one in eight
women in the United States [1]. More specifically,thesecond
most common type of cancer is breast cancer and
Nishikawa's fifth most common cause of cancer death [2].
Potentially fatal disease is nothing but breast cancer among
women who have reached 40 years. The breast cells
continue their growth and develop irregular breast tissue
shapes that lead to cancer. It is not exactly known the cause
of the disease. Many of the women's lives have been ravaged
by the disease when they are not diagnosed early. Early
detection is therefore the key to reducing breast cancer
death rates and increasing a patient's lifespan. Clinically
advised early detection successful tool that discloses breast
cancer tissues up to two years before a patient or physician
can feel or see some breast symptoms is mammography [ 1,
2].
Masses, calcifications, architectural distortion and observed
bilateral asymmetry are considered in mammographic
images as abnormalities. In various forms such as round,
oval, speculated, nodular lobulated and stellate, masses also
occur. In the present work, however, we are focusing on
finding the suspect area of obscure masses which is a very
important early-stage intervention to eliminate breast
cancer. While mammograms are an effective tool for early
detection, the detection of mammographic lesionsisdifficult
because all masses may not be cancer. The tissues that are
tightly compacted can also conceal some of the cancerous
masses, both look white and fatty tissue on black
background looks almost black. Therefore, recognizing the
area of early cancer detection to help radiologists survive as
a still warm automation mission. We have built an
appropriate framework in the proposed method to address
the difficulties addressed [3].
First, in the proposed study, each section is analyzed using
different segmentation techniques to understand the
foreground (breast region) and background (background)
area.
2. RELATED WORK
Micro calcification is one of the most importantsymptomsof
early breast cancer detection. image is acquired from the
mini mias repository and performs various steps such as
image enhancement, extractionoffeaturesandclassification.
In image enhancement, images are enhanced using filters
and features are extracted from the enhanced image using
Gabor filter and microcalcificationisclassifiedusingsupport
vector machine to categorize the masses into benign,
malignant [4].
A new model of effective contours for the identification of
features in an image based on curve evolution techniques,
Mumford–Shah for segmentation and level sets. The model
will detect objects whose boundaries are not automatically
described by gradient. It to reduce the energy that can be
considered as a specific case of a minimum partition
problem. The problem becomes a "mean-curvature flow"-
like evolving the effective contour in the level set
formulation which stops at the desired boundary.
Nevertheless, as in the classical active contour models, the
stop term does not depend on the gradient of the image, but
rather is connected to a specificsegmentationoftheimage.It
will use finite differences to give a numerical algorithm.
Ultimately, it will present different experimental resultsand
in particular some examples for which the gradient-based
classical snakes methods are not applicable.Theinitial curve
can also be detected anywhere in the image, and internal
contours are detected automatically [5].
A dynamic K-means clustering algorithm to find regions of
interest (ROI) in mammograms. This method is used to
divide an image into a set of regions (clusters or classes)
automatically. this approach consists of threephases:firstly,
preprocessing images using thresholding and filtering
methods; secondly, generating array of clusters by using
Local Binary Pattern (LBP) and applying k-means with its
features to automatically generate the optimal number of
clusters (hereafter k is the number of clusters generated);
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 883
thirdly, partitioning mammograms images into k clusters
Using the adaptive k-means clustering algorithm, end up
detecting regions of interest (ROI) in images of
mammograms. Here, it uses the Mini-MIAS (Mammogram
Image Analysis Society, UK) database of 322 mammograms
to illustrate the findings of method. The quality of system is
evaluated using ROC (FROC) Free Response curves. The
results archived are 2.84 false positives per image (FPpI)
and 85 percent sensitivity [6].
Digital mammography has become the most effective
method of early detection of breast cancer. Digital
mammogram takes and stores a digital image of the breast
directly on a screen. The purpose of the study is to build an
automated system to support virtual mammogram analysis.
Computer image processing techniques are applied to
improve images, accompanied by region of interest (ROI)
segmentation. The textural characteristics will then be
extracted from the ROI. The texture characteristics will be
used to classify the ROIs as masses or non-masses. In this
analysis, normal breast images are taken fromthe electronic
mammogramdatabaseofthe Mammographic ImageAnalysis
Society (MIAS) with masses usedasthestandardinputto the
proposed system. Masses are classified into speculated,
circumscribed and unknown in the MIAS list. Additional
information includes the location of centers of masses and
the mass radius. Using gray level co-occurrence matrix
(GLCM), which are constructed in four different directions
for each ROI, extracts the textural characteristicsofROIs[7].
3. METHODOLOGY
Image segmentation is a system in which an image is
partitioned into sections or regions. This division into
sections is often based on the image's pixel characteristics.
For example, looking for abrupt discontinuities in pixel
values, which typically indicate edges, is one way to find
regions in an image. Such edges are able to define regions.
Other ways of splitting the image into regions dependent on
color or texture values. Here we segmentthemammography
images. In the proposed study, eachsectionisanalyzedusing
different segmentation techniques to understand the
foreground (breast region) and background (background)
area. Different segmentation techniques are classified as:
1. Active contour: Segment image with active
contours (snakes) in the foreground and
background.
2. Gray threshes: Global image threshold using
Otsu's method.
3. Multithresh: Multilevel image thresholds using
Otsu’s method.
4. Otsu thresh: Global histogram threshold using
Otsu's method.
5. Adapt thresh: Adaptiveimagethresholdusinglocal
first-order statistics.
Active contour algorithm: Image processing is a technique
used to extract photo data. Segmentation is an image
processing segment designed to separate or segregate data
from the image's appropriatetargetarea.Varioustechniques
are used to segment pixels of interest from the image. Active
contour is one of the active models of segmentation
techniques, using the energy constraints and forces in the
image to distinguish the area of interest. Effective contour
determines a different boundary or curvature for the
segmentation regions of the target object. The contour
depends on different constraints that classify them into
different types such as gradient vector flow, balloon and
geometric models. Active contour modelsareusedprimarily
for medical image processing for various image processing
applications. Dynamic contours are used in medical imaging
in the segmentation of regionsfromdifferent medical images
such as brain CT images, MRI images of different organs,
cardiac images and different regions of the human body
pictures. For movement tracking and stereo tracking,
effective contours can also be used. Thus, for specific image
processing, the effective contour segmentation is used to
distinguish pixels of interest.
4. RESULT AND DISCUSSIONS
Fig -1: Original image
Fig 1 represents the mammographic image of original image
with tumor present. It’s a Malignant cell which represents
final stage of breast cancer.
Fig -2: Initial contour and final contour
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072
© 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 884
Fig 2 represents the mammographic image with active
contour algorithm is applied. We can see that, two lines of
figures present in it. It is the initial contour and final contour
of the represntation.With the help of these represntation, fig
3 of ROI segmentation is obtained.
Fig -3: Segmented image
5. CONCLUSION
In this paper, we suggest a method for segmenting the ROI
cell images of breast cancer collected through the mini-mias
data set. The segmentation method takes advantage of prior
knowledge that the leading protrusion of cancer cells is a
distinct high-level characteristic of cell boundaries relative
to other techniques. It performs Active contour technique to
segment the Roi of Breast cancer cell. It is an effective
method for segmenting the asymmetry portions of a
mammography image.
REFERENCES
[1] A. Gumaei, A. El-Zaart, M. Hussien, M., and M. Berbar,
“Breast Segmentation using K-means Algorithm with A
Mixture of Gamma Distributions”, IEEE 3rd SBNFI,
Lebanon, 28-29 May, 2012, pp. 97-102.
[2] J. Nagi, S. Abdul Kareem, F. Nagi, and S. K. Ahmed,
“Automated Breast Profile Segmentation for ROI
Detection UsingDigital Mammograms”,IECBES2010,30
Nov.- 2 Dec., 2010, Kuala Lumpur, Malaysia, pp. 87-92.
[3] BV Divyashree1, Amarnath R1, Naveen M1,GHemantha
Kumar* 1,”Novel approach to locate the region of
interest in mammograms for Breast
cancer”International Journal of Intelligent Systems and
Applications in Engineering IJISAE, 2018.,
[4] Cheng HD, Cai X, Chen XW, Hu L, Lou X (2003)
Computer-Aided Detection and Classification of
Microcalcifications in Mammograms: A Survey, Pattern
Recognition, 36: 2967–2991, 2003.
[5] T. F. Chan, and L. A. Vese, “Active contours without
edges”, IEEE Transactions on Image processing, vol. 10,
no. 2, pp. 266-277, 2001.
[6] X. Llado, A. Oliver, J. Mart, and J. Freixenet. “Dealingwith
false positive reduction in mammographic mass
detection”. In Medical Image Understanding and
Analysis, pp. 81-85, 2007.
[7] A. M. Khuzi, R. Besar, W. W. Zaki, and N. N. Ahmad,
“Identification of masses in digital mammogram using
gray level co-occurrence matrices” , Biomedical Imaging
and Intervention Journal, vol. 5, no. 3, 2009.
[8] V. D. Nguyen, D. T. Nguyen, T. D. Nguyen, and V. T. Pham,
“An Automated Method to Segment and Classify Masses
in Mammograms”, World Academy of Science,
Engineering and Technology vol. 3 no. 4, pp. 776-781,
Apr. 2009.
[9] A. M. Sabu, N. Ponraj, “Poongodi. Textural Features
Based Breast Cancer Detection: A Survey ”, Journal of
Emerging Trends in Computing and Information
Sciences, vol. 3, no. 9, pp. 1329-1334, Sep, 2012.
[10] S. D. Tzikopoulos, M. E. Mavroforakis, H. V. Georgiou, N.
Dimitropoulos, and S. Theodoridis, “A fully automated
scheme for mammographic segmentation and
classification based on breast density and asymmetry”,
Computer Methods and Programs in Biomedicine, vol.
102, no. 1, pp. 47-63, 2011.
[11] J. Suckling et al, “The Mammographic Image Analysis
Society digital mammogram database”,Exerpta Medica.,
International Congress Series 1069, pp. 375-378, 1994.
[12] Bozek J, Mustra M, Delac K, Grgic M (2009). A survey of
image processing algorithms in digital mammography.
Recent Advances in Multimedia Signal Processing and
Communications, SCI, 231, 631– 657.
[13] Sreedevi S, Sherly E (2015) A novel approach for
removal of pectoral muscles in digital mammogram.
Procedia Computer Science, 46: 724-1731.

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Detecting Breast Asymmetry Using Active Contour Segmentation

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 882 Detection of Breast Asymmetry by Active Contour Segmentation Technique Jincy Denny1, Mrs.Sobha T2 1M-Tech Student, Adi Shankara Institute of Engineering and Technology, Kalady, Kerala, India 2Professor, Dept. of Computer Science and Engineering, Adi Shankara College, Kalady, Kerala, India ---------------------------------------------------------------------***---------------------------------------------------------------------- Abstract - A method for the detection of the breast boundary in mammograms is provided. The approach started with adjustment of the original image's contrast. A binary technique was then applied to the image, and an approximate contour of the breast was found using the active contour algorithm in Matlab. Finally, the identification of the true breast boundary was carried out using the estimated contour as the input to a specifically tailored active contour model algorithm for this purpose. Key Words: Active contour algorithm, Matlab, Breast Asymmetry, contour segmentation, segmentation techniques 1. INTRODUCTION Breast cancer among women around the world is the most common type of cancer. Recent statistics suggest thatbreast cancer affects one in ten women in Europe and one in eight women in the United States [1]. More specifically,thesecond most common type of cancer is breast cancer and Nishikawa's fifth most common cause of cancer death [2]. Potentially fatal disease is nothing but breast cancer among women who have reached 40 years. The breast cells continue their growth and develop irregular breast tissue shapes that lead to cancer. It is not exactly known the cause of the disease. Many of the women's lives have been ravaged by the disease when they are not diagnosed early. Early detection is therefore the key to reducing breast cancer death rates and increasing a patient's lifespan. Clinically advised early detection successful tool that discloses breast cancer tissues up to two years before a patient or physician can feel or see some breast symptoms is mammography [ 1, 2]. Masses, calcifications, architectural distortion and observed bilateral asymmetry are considered in mammographic images as abnormalities. In various forms such as round, oval, speculated, nodular lobulated and stellate, masses also occur. In the present work, however, we are focusing on finding the suspect area of obscure masses which is a very important early-stage intervention to eliminate breast cancer. While mammograms are an effective tool for early detection, the detection of mammographic lesionsisdifficult because all masses may not be cancer. The tissues that are tightly compacted can also conceal some of the cancerous masses, both look white and fatty tissue on black background looks almost black. Therefore, recognizing the area of early cancer detection to help radiologists survive as a still warm automation mission. We have built an appropriate framework in the proposed method to address the difficulties addressed [3]. First, in the proposed study, each section is analyzed using different segmentation techniques to understand the foreground (breast region) and background (background) area. 2. RELATED WORK Micro calcification is one of the most importantsymptomsof early breast cancer detection. image is acquired from the mini mias repository and performs various steps such as image enhancement, extractionoffeaturesandclassification. In image enhancement, images are enhanced using filters and features are extracted from the enhanced image using Gabor filter and microcalcificationisclassifiedusingsupport vector machine to categorize the masses into benign, malignant [4]. A new model of effective contours for the identification of features in an image based on curve evolution techniques, Mumford–Shah for segmentation and level sets. The model will detect objects whose boundaries are not automatically described by gradient. It to reduce the energy that can be considered as a specific case of a minimum partition problem. The problem becomes a "mean-curvature flow"- like evolving the effective contour in the level set formulation which stops at the desired boundary. Nevertheless, as in the classical active contour models, the stop term does not depend on the gradient of the image, but rather is connected to a specificsegmentationoftheimage.It will use finite differences to give a numerical algorithm. Ultimately, it will present different experimental resultsand in particular some examples for which the gradient-based classical snakes methods are not applicable.Theinitial curve can also be detected anywhere in the image, and internal contours are detected automatically [5]. A dynamic K-means clustering algorithm to find regions of interest (ROI) in mammograms. This method is used to divide an image into a set of regions (clusters or classes) automatically. this approach consists of threephases:firstly, preprocessing images using thresholding and filtering methods; secondly, generating array of clusters by using Local Binary Pattern (LBP) and applying k-means with its features to automatically generate the optimal number of clusters (hereafter k is the number of clusters generated);
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 883 thirdly, partitioning mammograms images into k clusters Using the adaptive k-means clustering algorithm, end up detecting regions of interest (ROI) in images of mammograms. Here, it uses the Mini-MIAS (Mammogram Image Analysis Society, UK) database of 322 mammograms to illustrate the findings of method. The quality of system is evaluated using ROC (FROC) Free Response curves. The results archived are 2.84 false positives per image (FPpI) and 85 percent sensitivity [6]. Digital mammography has become the most effective method of early detection of breast cancer. Digital mammogram takes and stores a digital image of the breast directly on a screen. The purpose of the study is to build an automated system to support virtual mammogram analysis. Computer image processing techniques are applied to improve images, accompanied by region of interest (ROI) segmentation. The textural characteristics will then be extracted from the ROI. The texture characteristics will be used to classify the ROIs as masses or non-masses. In this analysis, normal breast images are taken fromthe electronic mammogramdatabaseofthe Mammographic ImageAnalysis Society (MIAS) with masses usedasthestandardinputto the proposed system. Masses are classified into speculated, circumscribed and unknown in the MIAS list. Additional information includes the location of centers of masses and the mass radius. Using gray level co-occurrence matrix (GLCM), which are constructed in four different directions for each ROI, extracts the textural characteristicsofROIs[7]. 3. METHODOLOGY Image segmentation is a system in which an image is partitioned into sections or regions. This division into sections is often based on the image's pixel characteristics. For example, looking for abrupt discontinuities in pixel values, which typically indicate edges, is one way to find regions in an image. Such edges are able to define regions. Other ways of splitting the image into regions dependent on color or texture values. Here we segmentthemammography images. In the proposed study, eachsectionisanalyzedusing different segmentation techniques to understand the foreground (breast region) and background (background) area. Different segmentation techniques are classified as: 1. Active contour: Segment image with active contours (snakes) in the foreground and background. 2. Gray threshes: Global image threshold using Otsu's method. 3. Multithresh: Multilevel image thresholds using Otsu’s method. 4. Otsu thresh: Global histogram threshold using Otsu's method. 5. Adapt thresh: Adaptiveimagethresholdusinglocal first-order statistics. Active contour algorithm: Image processing is a technique used to extract photo data. Segmentation is an image processing segment designed to separate or segregate data from the image's appropriatetargetarea.Varioustechniques are used to segment pixels of interest from the image. Active contour is one of the active models of segmentation techniques, using the energy constraints and forces in the image to distinguish the area of interest. Effective contour determines a different boundary or curvature for the segmentation regions of the target object. The contour depends on different constraints that classify them into different types such as gradient vector flow, balloon and geometric models. Active contour modelsareusedprimarily for medical image processing for various image processing applications. Dynamic contours are used in medical imaging in the segmentation of regionsfromdifferent medical images such as brain CT images, MRI images of different organs, cardiac images and different regions of the human body pictures. For movement tracking and stereo tracking, effective contours can also be used. Thus, for specific image processing, the effective contour segmentation is used to distinguish pixels of interest. 4. RESULT AND DISCUSSIONS Fig -1: Original image Fig 1 represents the mammographic image of original image with tumor present. It’s a Malignant cell which represents final stage of breast cancer. Fig -2: Initial contour and final contour
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 07 Issue: 02 | Feb 2020 www.irjet.net p-ISSN: 2395-0072 © 2020, IRJET | Impact Factor value: 7.34 | ISO 9001:2008 Certified Journal | Page 884 Fig 2 represents the mammographic image with active contour algorithm is applied. We can see that, two lines of figures present in it. It is the initial contour and final contour of the represntation.With the help of these represntation, fig 3 of ROI segmentation is obtained. Fig -3: Segmented image 5. CONCLUSION In this paper, we suggest a method for segmenting the ROI cell images of breast cancer collected through the mini-mias data set. The segmentation method takes advantage of prior knowledge that the leading protrusion of cancer cells is a distinct high-level characteristic of cell boundaries relative to other techniques. It performs Active contour technique to segment the Roi of Breast cancer cell. It is an effective method for segmenting the asymmetry portions of a mammography image. REFERENCES [1] A. Gumaei, A. El-Zaart, M. Hussien, M., and M. Berbar, “Breast Segmentation using K-means Algorithm with A Mixture of Gamma Distributions”, IEEE 3rd SBNFI, Lebanon, 28-29 May, 2012, pp. 97-102. [2] J. Nagi, S. Abdul Kareem, F. Nagi, and S. K. Ahmed, “Automated Breast Profile Segmentation for ROI Detection UsingDigital Mammograms”,IECBES2010,30 Nov.- 2 Dec., 2010, Kuala Lumpur, Malaysia, pp. 87-92. [3] BV Divyashree1, Amarnath R1, Naveen M1,GHemantha Kumar* 1,”Novel approach to locate the region of interest in mammograms for Breast cancer”International Journal of Intelligent Systems and Applications in Engineering IJISAE, 2018., [4] Cheng HD, Cai X, Chen XW, Hu L, Lou X (2003) Computer-Aided Detection and Classification of Microcalcifications in Mammograms: A Survey, Pattern Recognition, 36: 2967–2991, 2003. [5] T. F. Chan, and L. A. Vese, “Active contours without edges”, IEEE Transactions on Image processing, vol. 10, no. 2, pp. 266-277, 2001. [6] X. Llado, A. Oliver, J. Mart, and J. Freixenet. “Dealingwith false positive reduction in mammographic mass detection”. In Medical Image Understanding and Analysis, pp. 81-85, 2007. [7] A. M. Khuzi, R. Besar, W. W. Zaki, and N. N. Ahmad, “Identification of masses in digital mammogram using gray level co-occurrence matrices” , Biomedical Imaging and Intervention Journal, vol. 5, no. 3, 2009. [8] V. D. Nguyen, D. T. Nguyen, T. D. Nguyen, and V. T. Pham, “An Automated Method to Segment and Classify Masses in Mammograms”, World Academy of Science, Engineering and Technology vol. 3 no. 4, pp. 776-781, Apr. 2009. [9] A. M. Sabu, N. Ponraj, “Poongodi. Textural Features Based Breast Cancer Detection: A Survey ”, Journal of Emerging Trends in Computing and Information Sciences, vol. 3, no. 9, pp. 1329-1334, Sep, 2012. [10] S. D. Tzikopoulos, M. E. Mavroforakis, H. V. Georgiou, N. Dimitropoulos, and S. Theodoridis, “A fully automated scheme for mammographic segmentation and classification based on breast density and asymmetry”, Computer Methods and Programs in Biomedicine, vol. 102, no. 1, pp. 47-63, 2011. [11] J. Suckling et al, “The Mammographic Image Analysis Society digital mammogram database”,Exerpta Medica., International Congress Series 1069, pp. 375-378, 1994. [12] Bozek J, Mustra M, Delac K, Grgic M (2009). A survey of image processing algorithms in digital mammography. Recent Advances in Multimedia Signal Processing and Communications, SCI, 231, 631– 657. [13] Sreedevi S, Sherly E (2015) A novel approach for removal of pectoral muscles in digital mammogram. Procedia Computer Science, 46: 724-1731.