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Latin for
                             “poison”



A virus is a particle that can only be
seen with an electron microscope.   1
Viruses are not cells and are not made-up
of cells. They live only within a living cell
and have no attributes of a living organism

They don’t…
 Contain a nucleus or cytoplasm
 Eat
 Grow
 Carry on respiration
 Or perform other biological functions   2
• A virus is made up
  of genetic material
  inside a protein
  coat
• Viruses do not
  carry on most
  metabolic
  activities
• Viruses that only
  attack bacteria are
  called
  bacteriophages        3
A virus is surrounded by a capsid (protein
 coat) which determines the shape of the
 virus.
The capsid contains
nucleic acids
(either DNA or RNA).

Tail fibers
for attachment
to host cell.                           4
Viruses are classified by:
 type of host cell
 presence of DNA or RNA (retroviruses)
 shape:

                        Binal




     Polyhedral                                  5
                                          Filo
Naming Viruses
• After the disease   • Organism it
  it causes (ex.        affects (ex.
  Polio)                Tomato Mosaic)




                                         6
• People who
• Place where it’s
                        identify it (ex.
  found (ex. Ebola)     Epstein-Barr
                        virus)




                                           7
•   Viruses and bacteriophages invade cells
    and use the host cell's machinery to
    synthesize more of their own
    macromolecules.

•   Once inside the host the bacteriophage or
    virus will either go into a Lytic Cycle-
    destroying the host cell during
    reproduction.

        or

•   It will go into a Lysogenic Cycle - a
    parasitic type of partnership with
    the cell
VIRAL REPLICATION
Viruses replicate in one of two ways:
• Lytic
• Lysogenic




                                        9
Virus attaches to
                       LYTIC CYCLE
host cell.
                                     Virus injects its
                                     DNA



Cell lyses (breaks
apart) and new
viruses are
released

                                     Virus DNA
                                     commands host cell
                                     to make new viral
                                     parts

     New viral parts
     assembled


                                                10
11
LYSOGENIC CYCLE




                  12
LYSOGENIC CYCLE
• Does not begin immediately
• Viral DNA (called a prophage)
  attaches to the host cell’s
  chromosomes – lies dormant.
• The virus DNA integrates with the
  host DNA and the host’s cell helps
  create more virus DNA.
• Environmental stimulus sends viral
  DNA into lytic cycle.                13
VIRAL DISEASES
 Disease       Transmission              Symptoms
AIDS/HIV    Sexual contact;      Immune system failure;
            contaminated blood   fatal
            or needles
Common      Inhalation, direct   Sinus congestion, muscle
Cold        contact              aches, cough, fever
SARS        Inhalation, direct   Headache, discomfort,
            contact              body aches, chills
Influenza   Inhalation           Headache, muscle ache,
(Flu)                            sore throat, cough, fatigue,
                                 fever, chills
HPV         Sexual contact       Warts, may cause cervical
                                 cancer
Herpes      Direct contact       Open sores on mucus
                                 membranes             14
15
Most viruses have
       NO cure
(Influenza, & HIV),
 but some viruses
   like Small- pox
   have vaccines.

Vaccines contain a weakened or killed
  virus that provides immunity to the
                disease.         16
• http://acms7science.weebly.com/uploads/5/
  2/4/8/5248911/viruses.ppt.pdf
• http://freedownload.is/ppt/bacteria-and-
  viruses-21171792.html




                                          17

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Viruses

  • 1. Latin for “poison” A virus is a particle that can only be seen with an electron microscope. 1
  • 2. Viruses are not cells and are not made-up of cells. They live only within a living cell and have no attributes of a living organism They don’t…  Contain a nucleus or cytoplasm  Eat  Grow  Carry on respiration  Or perform other biological functions 2
  • 3. • A virus is made up of genetic material inside a protein coat • Viruses do not carry on most metabolic activities • Viruses that only attack bacteria are called bacteriophages 3
  • 4. A virus is surrounded by a capsid (protein coat) which determines the shape of the virus. The capsid contains nucleic acids (either DNA or RNA). Tail fibers for attachment to host cell. 4
  • 5. Viruses are classified by:  type of host cell  presence of DNA or RNA (retroviruses)  shape: Binal Polyhedral 5 Filo
  • 6. Naming Viruses • After the disease • Organism it it causes (ex. affects (ex. Polio) Tomato Mosaic) 6
  • 7. • People who • Place where it’s identify it (ex. found (ex. Ebola) Epstein-Barr virus) 7
  • 8. Viruses and bacteriophages invade cells and use the host cell's machinery to synthesize more of their own macromolecules. • Once inside the host the bacteriophage or virus will either go into a Lytic Cycle- destroying the host cell during reproduction. or • It will go into a Lysogenic Cycle - a parasitic type of partnership with the cell
  • 9. VIRAL REPLICATION Viruses replicate in one of two ways: • Lytic • Lysogenic 9
  • 10. Virus attaches to LYTIC CYCLE host cell. Virus injects its DNA Cell lyses (breaks apart) and new viruses are released Virus DNA commands host cell to make new viral parts New viral parts assembled 10
  • 11. 11
  • 13. LYSOGENIC CYCLE • Does not begin immediately • Viral DNA (called a prophage) attaches to the host cell’s chromosomes – lies dormant. • The virus DNA integrates with the host DNA and the host’s cell helps create more virus DNA. • Environmental stimulus sends viral DNA into lytic cycle. 13
  • 14. VIRAL DISEASES Disease Transmission Symptoms AIDS/HIV Sexual contact; Immune system failure; contaminated blood fatal or needles Common Inhalation, direct Sinus congestion, muscle Cold contact aches, cough, fever SARS Inhalation, direct Headache, discomfort, contact body aches, chills Influenza Inhalation Headache, muscle ache, (Flu) sore throat, cough, fatigue, fever, chills HPV Sexual contact Warts, may cause cervical cancer Herpes Direct contact Open sores on mucus membranes 14
  • 15. 15
  • 16. Most viruses have NO cure (Influenza, & HIV), but some viruses like Small- pox have vaccines. Vaccines contain a weakened or killed virus that provides immunity to the disease. 16
  • 17. • http://acms7science.weebly.com/uploads/5/ 2/4/8/5248911/viruses.ppt.pdf • http://freedownload.is/ppt/bacteria-and- viruses-21171792.html 17