Thyroid scintigraphy. Normal thyroid uptake of the gland. 99 `TcO4
Graves disease in a 24-year-old woman. Laboratory values were as follows: T4 = 16.7 μg/dL, T3 = 311 ng/dL, and TSH &lt; 0.01 μIU/mL. The 24-hour RAIU was 84%. Anterior distant image obtained with Tc-99m pertechnetate shows an enlarged thyroid. The target-to-background activity is increased to such an extent that the submandibular salivary glands (arrowhead) are barely visualized. Note the appearance of the pyramidal lobe (large arrow). The round photopenic area (small arrow) in this and subsequent figures represents the 2-cm lead marker placed at the suprasternal notch.
Typical pattern of Grave’s disease with uniform gland uptake and decreased background activity in the surrounding soft tissue
Autonomous nodules. patients with solitary &apos;hot‘ nodules of overactive thyroid tissue and relative suppression of the remainders
Late-stage Hashimoto thyroiditis
Scintigraphic pattern of thyroiditis where poor uptake and lack of delineation of thyroid gland borders are the typical features
Solitary &apos;cold&apos; nodules in three patients subjected to FNA. (A) Benign non-functioning adenoma (arrow); (B) carcinoma (arrows); (C) chronic thyroiditis affecting only the right lobe.
Thyroid scan and CT image (sagittal section) showing dual ectopia - sublingual and suprahyoid - with absence of normal thyroid
The patient with hemiagenesis presented with a neck swelling and a normal thyroid profile. The thyroid scan revealed normal tracer uptake in the right lobe of the thyroid and absent tracer uptake in the region of the left lobe of the thyroid. CT images confirmed the finding
The case of triple ectopia was a 20-year-old female who presented with a submandibular neck swelling. Her biochemical profile was suggestive of subclinical hypothyroidism. The thyroid scan revealed three areas of abnormal tracer uptake in the region of the base of the tongue and the suprahyoid and the subhyoid locations. CT images showed hyperdense soft tissue in the region of base of tongue and hyperdense tissue with cystic degeneration in suprahyoid and subhyoid locations
Imaging does not discriminate between iodide that is trapped in the thyroid and that which has been both trapped and organified.
Postoperative I-131 whole-body study with no functioning thyroid tissue in the neck or the rest of the body. Note the physiologic uptake in the salivary glands, stomach, and urinary bladder
I-123 24-h whole-body scan following surgical removal of thyroid gland for differentiated carcinoma. Residual neck thyroid tissue with or without residual tumor is evident (arrow)
Anterior and posterior views of an I-123 whole body scan of a patient with thyroid cancer after surgical resection who is now presenting for I-131 therapy. The scan shows multiple foci of intense activity in the neck, mediastinum, thorax, abdomen, and right humerus. These findings suggest widespread disease with bone involvement
Initial (a) and follow-up (b) I-123 24-h whole-body scans showing resolution of the neck activity (arrow) 1 year after I-131 postoperative ablation
image of an F-18 FDG PET/CT study of a patient with differentiated thyroid cancer showing residual tissue in the nick (arrow head)
Negative parathyroid study
Parathyroid adenoma. 99 &quot;&apos;Tc-MIBI images at 10 min (A) and 3 h (B) showing a persistent focus of activity inferior to the right lobe of the thyroid; image (C) shows normal thyroid uptake
Ectopic adenomas are usually sited in the superior mediastinum, often adjacent to the aortic arch