Basic physics of multidetector computed tomography ( CT Scan) - how ct scan works, different generations of ct, how image is generated and displayed and image artifacts related to CT Scan.
this power-point slide presentation includes lots of information like how MRI coil works. what is shimming, magnet, fringe, and design of mri coil and also magnet. this will help a lot for radiologist and technician radiographers.. thanks.
Magnetic Resonance Angiography and VenographyAnjan Dangal
Introduction to MR Angiography and Venography Procedure of Brain . Includes Indication, MRI protocol, planning and anatomy as well as brief intoduction to physics behind MRA and MRV principle.
Basic physics of multidetector computed tomography ( CT Scan) - how ct scan works, different generations of ct, how image is generated and displayed and image artifacts related to CT Scan.
this power-point slide presentation includes lots of information like how MRI coil works. what is shimming, magnet, fringe, and design of mri coil and also magnet. this will help a lot for radiologist and technician radiographers.. thanks.
Magnetic Resonance Angiography and VenographyAnjan Dangal
Introduction to MR Angiography and Venography Procedure of Brain . Includes Indication, MRI protocol, planning and anatomy as well as brief intoduction to physics behind MRA and MRV principle.
A review of advances in Brachytherapy treatment planning and delivery in last decade or so, with main focus on brachytherapy for Prostate cancer, Breast cancer and Cervical cancer
MRI artifacts remains a big challenge to get a diagnostic image. This represents a practical comprehensive approach to understand MRI artifacts & how to get rid of.
The journal publishes original works with practical significance and academic value. Authors are invited to submit theoretical or empirical papers in all aspects of management, including strategy, human resources, marketing, operations, technology, information systems, finance and accounting, business economics, and public sector management. IJMRR is an international forum for research that advances the theory and practice of management. All papers submitted to IJMRR are subject to a double-blind peer review process.
Mri image registration based segmentation framework for whole hearteSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
An Ultrasound Image Despeckling Approach Based on Principle Component AnalysisCSCJournals
An approach based on principle component analysis (PCA) to filter out multiplicative noise from ultrasound images is presented in this paper. An image with speckle noise is segmented into small dyadic lengths, depending on the original size of the image, and the global covariance matrix is found. A projection matrix is then formed by selecting the maximum eigenvectors of the global covariance matrix. This projection matrix is used to filter speckle noise by projecting each segment into the signal subspace. The approach is based on the assumption that the signal and noise are independent and that the signal subspace is spanned by a subset of few principal eigenvectors. When applied on simulated and real ultrasound images, the proposed approach has outperformed some popular nonlinear denoising techniques such as 2D wavelets, 2D total variation filtering, and 2D anisotropic diffusion filtering in terms of edge preservation and maximum cleaning of speckle noise. It has also showed lower sensitivity to outliers resulting from the log transformation of the multiplicative noise.
Conferencia impartida por Sebastián Sánchez en los Viernes Científicos organizada por la Facultad de Ciencias Experimentales de la Universidad de Almería el 14 de enero de 2011.
MNPS is a stereotactic planning and post-op evaluation system developed by Mevis Informatica Médica LTDA. Support for biopsy, functional neurosurgery, DBS, VTA, X-ray stereotactic localization, 2D-3D registration, image fusion, tractography and much more. Versions for a lot of frames manufactures and models; FiMe, Micromar, Bramsys, Leksell, CRW, BRW, ZD, Macom, Riechert-Mundiguer, Adeor-Zeppelin, EstereoFlex.
DBS support: Medtronic, St.Jude-Abbott, Boston Sc. and SceneRay.
A survey on Inverse ECG (electrocardiogram) based approachesIJMER
International Journal of Modern Engineering Research (IJMER) is Peer reviewed, online Journal. It serves as an international archival forum of scholarly research related to engineering and science education.
International Journal of Modern Engineering Research (IJMER) covers all the fields of engineering and science: Electrical Engineering, Mechanical Engineering, Civil Engineering, Chemical Engineering, Computer Engineering, Agricultural Engineering, Aerospace Engineering, Thermodynamics, Structural Engineering, Control Engineering, Robotics, Mechatronics, Fluid Mechanics, Nanotechnology, Simulators, Web-based Learning, Remote Laboratories, Engineering Design Methods, Education Research, Students' Satisfaction and Motivation, Global Projects, and Assessment…. And many more.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
3. • Image Artifact (brit. Artefact) is something observed in a
scientific investigation that is not naturally present but occurs
as a result of the investigative procedure. (oxford dictionary)
• A structure not normally present, but visible as a result of
malfunction in the hardware or software of the device, or a
consequence of environmental influences as heat or humidity
or can be caused by the human body itself.
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Introduction
4. • All MRI images have artifacts to some degree.
• Some are irreversible and may only be reduced while others
can be totally eliminated.
• Knowledge of artifacts a must for technologists to maintain
optimum image quality.
• Causes should be understood and compensated for if possible
to avoid being misjudged as pathology.
• Classified as to their basic principles,
Physiologic (motion, flow)
Hardware (electromagnetic spikes, ringing)
Inherent physics (chemical shift, susceptibility, metal)
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5. Artifacts caused by pt. motion
1. Ghosting and smearing:
Most common artifacts produced by motion of pt.(voluntary /
involuntary)
– From oesophageal contraction and vascular pulsation during head
and neck imaging,
– From respiration and cardiac activity during thoracic and abdominal
imaging,
– From bowel peristalsis during abdominal and pelvic imaging.
Occurs when there is magnitude and/or phase deviation from
optimal k-space encoding.
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6. Magnitude error - when a signal producing voxel changes
position during application of RF pulse.
Phase errors - Patient motion whenever a transverse component
of magnetization exists and motion is perp. to the applied
magnetic field Bo.
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7. Appearance of ghosting on final clinical image depends on
where in k-space such phase errors occur:
– If along the x-axis of k-space : frequency encoding direction
– If along y-axis : phase encoding direction
– If in middle of k-space : smearing appearance
– If phase errors are periodic (as in pulsatile motion), periodic ghosting.
Relatively more common in the phase encoding direction.
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8. Remedy
Total elimination impossible unless imaging a cadaver!!!!
• Various methods
a) Variants of rectilinear k-space filling techniques
Fast spin echo
Multisection imaging
Single shot single section imaging techniques
Parallel imaging
b) Radial k-space filling techniques
c) Cardiac gating and triggering
d) Respiratory gating
e) Navigator echo
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9. a) Variants of rectilinear k-space filling techniques
CSE : dominant because of relative insensitivity to field
inhomogeneity.
FSE/TSE : reduction in TA
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10. Multisection imaging
Several interleaved sections are imaged simultaneously
Helps further decrease acquisition time
Single shot single section imaging
Sequences such as the HASTE are more resistant to motion
Allow more rapid acquisition by filling only half of k-space.
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11. Parallel imaging :
involves filling of selected lines in k-space at a predetermined interval.
Requires use of multichannel, multicoil technology, with each coil
possessing a distinct, known sensitivity profile over the FOV and with
at least two coils placed in the phase encoding direction.
The no. of phase encoding steps can be reduced by a factor of 1/X,
where X is the parallel imaging factor (2 or 3).
Thus image acquisition proceed X times faster by filling only one of
every X lines(2nd or 3rd ) of k-space in phase encoding direction and
by known coil sensitivity profiles to synthesize other lines.
Eg: GRAPPA (siemens), SENSE (philips), SMASH
5/5/2013 MRI artifacts-sudil 11
13. b) Radial k-space filling techniques
Standard line by line filling of k-space replaced by radial k-space filling
with the use of a multishot radial acquisition technique (eg.
syngoBLADE, Siemens healthcare; PROPELLER, GE healthcare)
MR imaging datasets acquired in multiple overlapping radial sections,
each of which includes data sampled from the center to the periphery
of k- space.
A series of low resolution images is first reconstructed from each
radial section and combined to produce a high resolution image.
As the phase encoding direction varies with each radial section,
ghosting is not propagated in PE direction but is dispersed throughout
radial sections and thus has a lesser effect on final image.
Also provide correction for in-plane rotation and bulk translational
movement.
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15. c) Cardiac gating and triggering
Cardiac motion periodic, both static and cine images
Cine imaging performed by using a balanced SSFP that
produces tissue contrast based on ratio of T1 to T2, lending
blood a high signal intensity (so called bright blood
imaging).
Cine imaging performed with retrospective cardiac gating
i.e.
a series of MR images of a single anatomic section are acquired
during cardiac cycle, monitored with ECG.
Data within k-space are linked with specific time point in cardiac
cycle.
The acquired datasets are then sorted acc to time stamp to
produce sequential images allowing a dynamic evaluation of
myocardial function.
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16. For static images to evaluate cardiac structure and not cardiac
func., prospective triggering is used and image acquisition is
usually timed to occur during the end diastole.
In triggering a certain no. of k-space lines is acquired during
pt. breath holding for a given heartbeat.
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17. d) Respiratory gating
Infrequently used in clinical imaging as compared to cardiac gating.
Breath holding method most often used, but may not be feasible for
infants, children, and pt.s with respiratory or cognitive impairment.
Sequences with short acquisition time may be used, or if breath
holding possible for limited time, exam may be divided into several
brief acquisitions.
If none is possible, respiratory gating.
in which respiration related motion is monitored, using bellows or
breathing belt, image acquisition is timed to take place at end
expiration, when there is little or no motion.
Phase reordering with either COPE or ROPE.
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18. e) Navigator echo
Most commonly used in abdominal imaging at the interface of lung
and diaphragm
Application of small, one dimensional spatial encoding gradient in a
plane perpendicular to diaphragm.
Echo measured at this location allows correction of imaging dataset to
ensure that, only the imaging data acquired, when diaphragm is at its
peak (end expiration), are used in image reconstruction.
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19. Motion artifact contd..
2. Pulsatile flow-related artifacts
Periodic pulsation of vascular structures leads to ghosting in phase
encoding direction at constant intervals.
Distance between ghosts depends on diff. between heart rate and TR;
if synched, no ghosting.
Macroscopic motion eg. Blood in large vessels or CSF in spinal canal
also contribute to ghosting.
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20. Remedy
a) ECG gating :
– time consuming, seldom used except for cardiac imaging
b) Gradient moment nulling:
– Application of additional gradient pulses to correct for phase shifts
among a population of moving protons at the time of echo collection.
– Corrects for constant-velocity motion and helps reduce the signal loss
and ghosting associated with such movement.
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21. c) Saturation pulse:
– Additional RF pulses applied before the sequence in a plane
perpendicular or parallel to imaging plane
– As applied at the beginning of sequence, their use may reduce the no.
of imaging secitons that can be obtained per TR in multisection
acquisitions.
– Also when SAR is already high, use of saturation pulse may result in
excessive heat deposition.
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22. Artifacts caused by field distortions
1. Eddy currents
source of spatial and temporal distortions in Bo.
most frequently encountered in clinical DWI because of the high
amplitude and long duration of diffusion- sensitizing gradients.
When diffusion gradient applied, change in magnetic field creates
electrical currents in neighboring conductive surfaces. Such currents
create smaller magnetic fields (i.e. eddy currents) that modify Bo.
modern gradient coils equipped with active shielding to avoid these
effects of electrical conduction, eddy currents are not as obtrusive in
routine clinical imaging as they were in the past.
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23. 5/5/2013 MRI artifacts-sudil 23
Remedy
Pre-compensation- A “distorted” gradient waveform is used which
corrects to normal with the eddy current effects.
Shielded gradients – Active shielding coils between gradient coils and main
gradients.
24. 2. Gradient field nonlinearity
Occurs in all MR imaging systems and primarily related to gradient
falloff due to the finite size of the gradient coils.
Predictable.
Easily corrected by system software, with corrections applied before
the final images are constructed.
Operator unaware of occurrence of mapping errors due to gradient
field nonlinearity.
Although post processing techniques can correct distortions resulting
from gradient field nonlinearity, cannot compensate for losses in
spatial resolution that are related to gradient field nonlinearity.
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25. 3. RF field inhomogeneities
Do not cause geometric distortions but contribute to signal
nonuniformity.
May arise from problems in RF coil construction or standing wave
(dielectric) effects.
Because the Larmor frequency of protons increases with increasing
field strength, a high-frequency pulse is needed to excite signal
producing protons at MR imaging with high field strengths such as 3 T.
When the RF wavelength is shorter than the dimensions of the
anatomic structures examined at clinical MR imaging, standing waves
may result.
Leads to inhomogeneous fat suppression.
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26. 5/5/2013 MRI artifacts-sudil 26
Remedy
Shimming- allows precise control of overall homogeneity of RF field.
Use STIR for Fat sat than spectral tech. like CHESS.
Dielectric – use phased array coils, software compensation
27. Aliasing artifacts
• Field of view:
– dimensions of the anatomic region to be included in imaging.
– mathematic product of the acquisition matrix and pixel dimensions.
– Chosen considering size of structure to be evaluated and trade-offs
between SNR and spatial resolution.
– With a constant imaging matrix, a smaller FOV results in higher spatial
resolution but lower SNR.
• Choosing an FOV that is smaller than the area imaged leads to
wraparound or aliasing artifacts.
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28. • Echoes are sampled along the FE direction at the sampling bandwidth
rate, with higher rates resulting in a greater range of frequency sampling.
• Nyquist frequency - highest frequency that may be clearly sampled, with
higher frequencies corresponding to tissues outside the specified FOV.
• High frequencies outside the FOV falsely detected as lower frequencies
which leads to a wraparound artifact on the reconstructed images.
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30. 5/5/2013 MRI artifacts-sudil 30
Remedy
• Increase the FOV (decreases resolution).
• Oversampling the data in the frequency direction (standard)
and increasing phase steps in the phase-encoded direction –
phase compensation (time or SNR penalty).
• Swapping phase and frequency direction so phase is in the
narrower direction.
• Use surface coil so no signal detected outside of FOV.
• Saturation pulses may also be applied to structures in the
nonimaged portion of the FOV to reduce signal and, thus,
signal overlap.
31. Magnetic susceptibility artifacts
Inaccurate spatial encoding from susceptibility gradients within tissue
leads to distortion of anatomic structures.
Artifact resulting from the presence of metallic objects, not only distorts
nearby structures but also may result in signal dropout, depending on the
sequence used.
The effects are field strength dependent, and the potential for metallic
object–related artifacts is greater at 3 T than at lower magnetic field
strengths.
However, the increase in magnetic field strength from 1.5 to 3 T results in
a significant improvement in SNR, allowing the use of a higher bandwidth
sampling rate and parallel imaging to reduce susceptibility artifacts.
Worst with long TE and gradient echo sequences.
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33. 5/5/2013 MRI artifacts-sudil 33
Remedy
Imaging at low magnetic field strength, using smaller voxels, decreasing
echo time, and increasing receiver bandwidth.
Gradient-echo and echo-planar sequences should be avoided, because
they increase susceptibility artifacts.
The use of spin-echo and particularly fast spin-echo sequences should be
considered.
34. Chemical shift artifacts
Protons in fat and water precess at different frequencies in an applied
magnetic field.
The separation between their resonance frequencies increases with
increasing field strength.
Eg. At 1.5 T , freqency diff. is 220 Hz, but at 1 T the diff. is 147 Hz and at
lower field strengths (0.5 T or less ) usually insignificant.
The chemical shift differences lead to spatial misregistration of the MR
signal; i.e. differences in the Larmor frequency are mistaken for
differences in spatial position along the frequency encoding axis.
The resultant chemical shift artifacts on images manifest most
prominently at fat-water interfaces.
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35. Amount of chemical shift is expressed in arbitrary units known as parts per
million (ppm) of Bo.
It’s value is always independent of Bo and equals 3.5 ppm.
Occurs in the frequency encoding direction only.
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36. Remedy
Imaging at low magnetic field strength,
by increasing receiver bandwidth, or by decreasing voxel size.
T1-weighted- The artifacts tend to be more prominent on T2-
weighted than on T1-weighted images.
Fat suppression methods often eliminate.
5/5/2013 36MRI artifacts-sudil
37. Chemical misregistration artifact
Also produced as a result of the precessional frequency diff.
between fat and water.
But this is caused because fat and water are in phase at
certain times and out of phase at others, due to difference in
their precessional frequency.
When they are in phase their signals add constructively and
when out of phase the signals cancel each other out.
This cancellation effect is known as chemical misregistration
artifact.
5/5/2013 MRI artifacts-sudil 37
38. Causes a ring of dark signal around certain organs where fat and
water interfaces occur within the same voxel. Eg. Kidneys
Mainly occurs in PE direction as it is produced due to phase
difference between fat and water.
Most degrading to the image in gradient echo pulse sequences
where gradient reversal is very ineffective.
5/5/2013 MRI artifacts-sudil 38
39. Remedy
Use SE sequence
In GRE, select a TE that corresponds to the periodicity of fat and
water
ie. Select a TE that generates an echo when fat and water are in
phase.
5/5/2013 MRI artifacts-sudil 39
40. Partial volume artifacts
Partial volume occurs if slice thickness > thickness of tissue of
interest
Occurs when multiple tissue types are encompassed within a single
voxel
If small structure is entirely contained within the slice thickness
along with other tissue of differing signal intensities,
the resulting signal displayed on the image is a combination of
these two intensities.
This reduces contrast of the small structure.
If the slice is the same thickness or thinner than the small structure,
only that structures signal intensity is displayed on the image.
Volume averaging is most likely to occur in the slice-selection
direction of the image.
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41. 5/5/2013 MRI artifacts-sudil 41
Remedy
Decreasing voxel size, particularly reducing section thickness.
Three-dimensional Fourier transform imaging is particularly useful,
because it provides thin sections with no intervening gaps and is
conductive to reformatting in alternate imaging planes.
Multiplanar imaging option helps to clarify.
42. Signal truncation artifacts
Occur in regions of boundary between high and low signal intensity
Caused by approximation errors in Fourier transform analysis.
As the signal is sampled over a limited period of time, some data
are necessarily omitted (truncated) in k-space, causing the signal
intensity of a given pixel on the final image to vary from its ideal
signal intensity.
Commonly seen at the interface of the low-signal intensity spinal
cord with high-signal-intensity CSF on T2WI of the spine, mimic
spinal canal dilatation (ie. Hydromyelia,syrinx).
Appears as a periodic “ringing” at high contrast interfaces.
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43. 5/5/2013 MRI artifacts-sudil 43
128x256
256x256
Remedy
• Use of higher resolution imaging matrix and filtration methods.(under
sampling avoided)
• Gradient reorientation will displace the artifacts to another portion of the
image.
44. Slice-overlap (cross-slice) artifacts
• Loss of signal seen in an image from a multi-angle, multi-slice
acquisition.
• If the slices obtained at different disk spaces are not parallel, then
the slices may overlap when two levels are done at the same time,
e.g., L4-5 and L5-S1.
• The level acquired second will include spins that have already been
saturated.
• This causes a band of signal loss crossing horizontally in image,
usually worst posteriorly.
• Therefore, overlap of sections within areas of diagnostic interest
should be carefully avoided.
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45. 5/5/2013 MRI artifacts-sudil 45
Remedy
Avoid steep change in angle between slice groups.
Use separate acquisitions.
Use small flip angle.
46. Cross-excitation artifacts
• The imperfect shape of RF slice profiles leads to the unintended
excitation of adjacent tissue.
• This excitation results in the saturation of such tissue
• Manifest as decreased signal intensity and decreased contrast that
can hinder lesion detection.
5/5/2013 46MRI artifacts-sudil
47. Remedy
• Introduce an intersection gap that is 10% to 50% of the
prescribed section thickness.
• Interleaved image acquisition, in which odd-numbered
sections are initially acquired,followed by acquisition of even-
numbered sections.
• optimized RF pulses that have a more rectangular slice profile
can be implemented.
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48. Cross-talk Artifact
Perfect RF pulse is a sinc function (FT = ‘top hat’)
Real RF pulse is a truncated sinc (FT = ‘top hat with rounded
edges’)
Result of imperfect slice excitation of adjacent slices causing
reduction in signal over entire image.
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49. 5/5/2013 MRI artifacts-sudil 49
• Inter-slice cross talk could cause increased T1 weighting and
reduced SNR.
• May be reduced by using gap, interleaving slices and
optimized (but longer) RF pulses.
50. Magic Angle Effects
Produced by the particular physical properties of fibrillary tissues and their
interaction with the static magnetic field.
Seen most frequently in tendons and ligaments that are oriented at a 55o
angle to the main magnetic field.
Due to dipolar interactions that reduce their T2 relaxation time.
Normal dipolar interactions between the H+’s in water molecule aligned in
tendons shortens T2, causing loss of signal.
T2 relaxation time is lengthened and maximal when these fibrillary
structures are at a 55° angle to B0.
Maximal for short TE.
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52. Zipper Artifacts
• Most are related to hardware or software problems
• May occur in either frequency or phase direction.
• Zipper artifacts from RF entering room during image
acquisition are oriented perpendicular to the frequency
direction and easily controlled.
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53. Spike artifact
• Caused by one ‘bad’ data point in k-space.
• Fig. shows one data point in k-space, which is out of the
ordinary.
• The resulting image show diagonal lines throughout the
image.
Remedy - Repeat the scan.
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54. Zebra stripes
• Observed along the periphery of gradient-echo images (abrupt
transition in magnetization at the air-tissue interface)
• Increased by aliasing that results from the use of a relatively small
field of view.
• May also occur when pt. touches the coil or a result of phase wrap.
Remedy
• expanding the FOV, using SE pulse sequences.
• using oversampling techniques to reduce aliasing.
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55. RF Overflow Artifacts (Clipping)
Causes a nonuniform, washed-out appearance to an image.
Occurs when the signal received from the amplifier exceeds
the dynamic range the analog-to-digital converter causing
clipping.
Autoprescanning usually adjusts the receiver gain to prevent
this from occurring.
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56. Moire Fringes
An interference pattern most commonly seen when doing gradient
echo images.
One cause is aliasing of one side of the body to the other results in
superimposition of signals of different phases that add and cancel.
Can also be caused by receiver picking up a stimulated echo.
Similar to the effect of looking though two window screens.
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57. Central Point Artifact
• A focal dot of increased or decreased signal in the center of an
image.
• Caused by a constant offset of the DC voltage in the
amplifiers.
Remedy
Requires recalibration by engineer
Maintain a constant temperature in equipment
room for amplifiers.
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58. Quadrature ghost artifact
• Another amplifier artifact caused by unbalanced gain in the two
channels of a quadrature coil.
• Combining two signals of different intensity causes some
frequencies to become less than zero causing 180 degree “ghost.”
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59. Entry slice (Inflow) phenomenon
• Unsaturated spins in blood or CSF entering the initial slices results in
greater signal then reduces on subsequent slices.
• Characterized by bright signal in a blood vessel (artery or vein) at entry
site.
• May be confused with thrombus.
• The use of gradient echo flow techniques can be used to differentiate
entry slice artifacts from occlusions.
• Can cause spatial saturation to reduce.
• Mechanism for TOF angiography.
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60. Shading artifacts
Produces a loss of signal intensity in one part of image.
Main cause is uneven excitation of nuclei within the pt. due to RF
pulses applied at flip angles other than 90* and 180*
Also caused by abnormal loading on coil or by coupling of coil at
one point. This may occur with large pt. who touches one side of
the body coil and couples it at that point.
Appear as foci of relatively reduced signal intensity involving a
portion of the image.
Abnormalities contained in the shaded portion of the MR image
may be obscured.
Also be caused by inhomogeneities in the main magnetic field that
can be improved by shimming.
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61. Remedy
• Always ensure that coil is loaded correctly i.e correct size of coil for
anatomy under examination, and pt. is not touching the coil at any point.
• Use of foam pads or water bags bet.n coil and patient
• Ensure that appropriate pre-scan parameters have been obtained before
the scan, as these determine the correct excitation frequency and
amplitude of applied RF pulses.
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62. Conclusion…
• Artifacts in MR images are an inevitable truth.
• MRI arifacts occur because one or more of the assumptions underlying the
imaging principles have been violated.
• Some can be reduced while others can be totally eliminated.
• Artifact correction methods usually involve one or more of the following:
Hardware calibration
Scanning parameter optimization
Special pulse sequence design
Signal and image postprocessing
• By understanding the mechanism of their production and their effects on the final
image, technologists should considerably try to minimize these artifacts with the
use of reduction techniques.
• Ideally, we want all image artifacts to be below the level of user's perception.
• Artifact correction is an active area of research today, and will continue to be in
the future as advances in MRI technology reveal new image information and new
kinds of artifacts.
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64. Find more at….
1. Morelli JN, Runge VM, Ai F, et.al. An Image-based Approach
to Understanding the Physics of MR Artifacts. RadioGraphics
2011; 31:849–866
2. MRI in practice, 2nd edn. By Catherine Westbrook and
Carolyn Kaut
3. MRI artifacts, PPT presentation by Ray Ballinger
4. MRI physics course; Artifacts and suppression technique by
Jerry Allisson
5. www.mr-tip.com
6. www.mritutor.org
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65. On examining a knee with prosthesis in situ, what artifact is
expected?
Difference between chemical shift and chemical
misregistration
Truncation artifact and reduction
List different motion compensation options.
Why is motion artifact seen only in PE direction?
What are the sources of zipper artifact?
Why does aliasing occur?
Difference between cross talk and cross excitation.
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SE consists of a 90* RF followed by 180* RF pulse before echo, with each iteration ie. TR period filling a single line of k-space.FSE allow reduction in TA by filling the time between acquisition of echo and end of given TR with additional 180* refocusing pulses and signal echoes to fill additional lines in k-space. The no. of additional echoes obtained is known as echo train length.
Figure 5. Axial T2- weighted images of the brain depict a ghosting artifact caused by patient motion when a standard fast spin-echo sequence was used (a) and the absence of ghosting when a radial k-space sampling method (syngoBLADE) was used (b)
Figure 6. Oblique axial (a) and sagittal (b) cine SSFP images obtained with prospective cardiac gating (triggering) depict hypertrophic cardiomyopathy in a 47-year-old man. Four chamber (a) and two-chamber (b) views show a decreased left ventricular volume during systole, with significant thickening of the lateral wall of the left ventricle and the interventricular septum. Cardiac triggering allowed the acquisition of diagnostic MR images with a high SNR, high spatial resolution, and absence of artifact caused by motion of the beating heart.
Placement of the navigator section for respiratory motion compensation. (a) Image with aqua overlay shows the navigator section from which the displacement information is obtained to determine the diaphragmatic position. (b) Graph shows diagphragmatic movement, indicated by the white wave and green line. The yellow boxes represent the best time to image (“window of opportunity”).
Schematics show the MR signal effects of flow compensation with gradient moment nulling. Top: Typical readout gradient waveform. Bottom: Phase of stationary spins (solid line) and constant-velocity spins (dotted and dashed lines). (a) During imaging without flow compensation, the moving spins are not refocused at the desired echo time (TE), and this leads to the loss of signal from flowing spins. (b) During imaging with gradient moment nulling, all the spins are refocused, and flow velocity is compensated for by the 1:2:1 ratio of the gradient lobe areas
(a) Sagittal T1-weighted image of the cervical spine shows areas of low signal intensity (arrows) that represent ghosting artifacts caused by esophageal motion related to swallowing. (b) Sagittal T1-weighted image obtained with a preparatory saturation pulse applied in a plane anterior to the spine shows the absence of the artifacts seen in a.
Fig: coronal T1W GRE images of posterior abdomen acquired on a 1.5 T system. Left image was taken with TE of 2.8 ms whereas right image has TE of 4.2 ms. The arrow shows chemical misregistration artifact.
Axial T1WI of the brain at exactly the same level. Second image shows 7th and 8th cranial nerves (arrow) but the first one merely depicts them. The reason for this is the partial volume averaging. The first slice was taken at thickness of 10 mm while second slice was taken at 3 mm.