Nanotechnology in dentistry

1. NANOTECHNOLOGY IN
DENTISTRY
HABIBA HABIB ,KAREN GEORGE ,MARIAM SHEHAB
SEMESTER FOUR
UNDR SUPERVISION OF : A.PROF SAMAH KAMEL

2. WHAT IS NANOTECHNOLOGY?
• Nanotechnology is the use of structures varying between 1-100
nm.
• It involves imaging, modeling, manipulating materials and
measuring.
• It is used among all fields of sciences.
• To help you imagine more: 100,000 nm

3. APPLICATIONS IN DENTISTRY:
• Nanorobotic Local Anesthetics
• Dentin Hypersensitivity
• Nanomaterials
• Preventing caries
• Nanocomposite Artificial teeth
• Dental Materials
• Nanoneedles

4. DENTAL MATERIALS
• Nanofillers are added to impression materials to increase flow for
better reproduction of details (vinyl polysiloxanes).
• Added to composite resin to increase fracture resistance and improve
mechanical properties.
• Nanofilled Glass–Ionomer Cements Hydroxyapatite and fluorapatite
nanofillers have been added to commercial GIC and have been shown
to increase the compressive, tensile and flexural strength and
enhance the bond strength to dentine.

5. NANOROBOTIC LOCAL ANESTHETICS
• Composed of a colloidal solution of activated nanosized local anesthetic
molecules.
• The anesthetic travels via the gingival sulcus, lamina propria or dentinal
tubules to reach the pulp.
• Once the pulp is reached, they take control over the nerve-impulse traffic.
• On completion of the procedure, the nanorobots may again be signaled to
restore the sensation.
• The nanorobots are either ordered to egress through the same pathway they
entered or in cases of biodegradable nanorobotics they self-destruct.

6. BENEFITS OF NANOROBOTIC LOCAL
ANESTHETICS
• Less anxiety and better patient
compliance as it is a needleless procedure.
• Anesthesia can be maintained as long as desired.
• Lack of side-effects and minimizing the risk of complications.

7. ORAL CANCER
• Nanotechnology-based drug delivery systems.
• Detecting cancer biomarkers accurately.
• Nano assemblers: a solution which contains
millions of microscopic elements.
• Nanoparticles activate immune cells.
• Management of the pain associated with cancer. Kaposi’s sarcoma on
buccal mucosa

8. GENERAL ADVANTAGES
• Improves osseointegration, infection control.
• Biocompatibility of dental implants may reduce the rejection
rates in some invasive procedures.
• Control and direct pulp stem cells in order to regenerate the
tooth.

9. HAZARDS
• Accumulation of nanobiomaterials in tissues may cause
unwanted reactions.
• Metal oxides cause DNA damage.
• Some studies show that it may be toxic in some cases.

10. REFERENCES
• https://pocketdentistry.com/2-8-nanotechnology-in-dental-materials/ 2015
• https://www.aegisdentalnetwork.com/cced/2017/05/nanotechnology-in-
dentistry-clinical-applications-benefits-and-hazards 2017
• https://annalsofdentalspecialty.net.in/storage/models/article/0TJR6kTbT5JEO1I
aBuPShXPM4ws4fiunYcirTNYOymlgjYOpCf9Bg2S22dtE/4-nanorobotics-in-
dentistry-lumbini-p-agarwal-p-kalra-m-karthik-km-pdf.pdf 2014
• https://www.frontiersin.org/articles/10.3389/fnins.2020.00033/full 2020
• 117. Brewer E, Coleman J, Lowman A. Emerging technologies of polymeric
nanoparticles in cancer drug delivery. J Nanomater. 20112011:408675.
• 12. Gau V, Wong D. Oral fluid nanosensor test (OFNASET) with advanced
electrochemical-based molecular analysis platform. Ann N Y Acad Sci.
2007;1098:401-410.
• Mahapatro A, Singh DKJ Nanobiotechnology. 2011 Nov 28; 9():55.
• Moore F.N., The implications of nanotechnology applications: using genetics as
a lesson. Health Law Review, 10:3.

11. THANK YOU!!