General Principles of Intellectual Property: Concepts of Intellectual Proper...
Factors affecting dentogingival junction
1. Done by: Iten Abdalfattah ,Rana Alaa ,Mayar Said ,Abeer
Ahmed
Semester Four
Under Supervision of : A.Prof. Samah Kamel
2. It is the interface and
zone of attachment
between the gingiva
and enamel or
cementum of the tooth.
It holds in place the
junctional or
attachment epithelium.
4. Type I and type II of primary diabetes mellitus leads to
periodontal disease, due to uncontrolled blood glucose
level.
The chronic hyperglycemia leads to:
Production of AGEs which binds to macrophage,
making it hyper-reactive and produce pro-
inflammatory cytokines.
AGEs binds to endothelial cells, making it hyper
permeable and hyper expressive for adhesion to
molecules.
5. AGEs makes the
fibroblast produce less
collagen, which leads to:
Hyper-inflammatory
responses.
Vascular modification.
Altered healing of
wounds.
Occurrence of
periodontitis and
gingivitis.
6. Nicotine found in cigarette
activates the release of
epinephrine, this
substance promote VC of
gingival blood vessels,
which cause a reduction in
the blood flow leading to:
Loss of vitality of gingival
epithelium.
Helps in onset of gingival
ulceration (ANUG).
7. Usually, it does not cause any damage to the gingival tissues, but in some
patients it may cause some changes which subsequently leads to gingival
retraction on the labial surface of incisors and canines and on the buccal
surface of posterior teeth.
Orthodontic treatment
8. Loss of supporting bone by
inflammatory process.
Loss of tissue by enzymatic
digestion.
These two leads to apical
migration of the gingiva
and exposure of the root,
this is known as gingival
recession.
