What do we actually know about the 100 trillion bacteria that live on and inside our bodies? Alexandra Carmichael, formerly of Quantified Self, CureTogether, and 23andMe, gave this talk at SXSW in Austin on March 16th, 2015.
This presentation include microbiome involve in human health and disease. classification and categorization of microbiota is aslo given.Anatomical area in which these microbes present.
Ecological Disturbance of the Human Gut MicrobiomeAnne M. Estes
Set of slides discussing the importance of microbes for human health. Made to accompany the hands-on activity "Modeling the Dynamic Digestive System Microbiome" published: http://www.asmscience.org/content/journal/jmbe/10.1128/jmbe.v16i2.908
Your body is home to three pounds of germs, a rich microbiome that weighs as much as your brain! Thanks to the recent plummeting cost of gene sequencing, scientists are just now discovering how important these microbes are to health and wellness, with surprising links to conditions ranging from obesity, autism, allergies, depression, and much more. We’ll discuss the latest developments, and show how new, low-cost testing kits can help you learn more about — and reshape — your own unique microbiome.
Mapping the Human Gut Microbiome in Health and Disease Using Sequencing, Supe...Larry Smarr
Invited Talk Delivered by Mehrdad Yazdani, Calit2 Ayasdi Sponsored Lunch & Learn American Society of Human Genetics (ASHG) San Diego Convention Center October 19, 2014
This presentation include microbiome involve in human health and disease. classification and categorization of microbiota is aslo given.Anatomical area in which these microbes present.
Ecological Disturbance of the Human Gut MicrobiomeAnne M. Estes
Set of slides discussing the importance of microbes for human health. Made to accompany the hands-on activity "Modeling the Dynamic Digestive System Microbiome" published: http://www.asmscience.org/content/journal/jmbe/10.1128/jmbe.v16i2.908
Your body is home to three pounds of germs, a rich microbiome that weighs as much as your brain! Thanks to the recent plummeting cost of gene sequencing, scientists are just now discovering how important these microbes are to health and wellness, with surprising links to conditions ranging from obesity, autism, allergies, depression, and much more. We’ll discuss the latest developments, and show how new, low-cost testing kits can help you learn more about — and reshape — your own unique microbiome.
Mapping the Human Gut Microbiome in Health and Disease Using Sequencing, Supe...Larry Smarr
Invited Talk Delivered by Mehrdad Yazdani, Calit2 Ayasdi Sponsored Lunch & Learn American Society of Human Genetics (ASHG) San Diego Convention Center October 19, 2014
Microbes are our Friends.. The effective way of microbes treating our diseases and fighting with the pathogens is very effective. The human microbiome project is a current topic the researchers are focusing now. We think we are humans but the research of Human Microbiome Project states that we are 1% Humans 99% microbes. The highlights of this project is fecal transplantation and effective way of killing pathogens with the positive microbes.
The way we treat our body will treat you back and the antigens which are entered in to our body will greatly fight with microbes to survive and make the human body safe and healthy.
Finally Microbes are us and we are them
Jonathan Eisen talk at #UCDavis 10/19/15 on "Microbiomes in Food and Agricult...Jonathan Eisen
Slides for talk on "Microbiomes in Food and Agriculture" by JonathanEisen - note - not all slides were used in talk. These were there to stimulate discussion ...
These slides explores in general the discovery of the human microbiome, and the important roles they play in our well-being. Humans have evolved to live with microbes, this symbiotic relationship is crucial. Humans are in fact 'supra-organisms' that exhibit both human and microbial traits.
Microbiome Diagnostics Platform for Microbiome Health and Colon Cancer Preven...Laura Berry
Presented at the 4th Microbiome R&D and Business Collaboration Forum: USA. To find out more, visit: www.global-engage.com
Greg Kuehn, President and COO of Metabiomics, presents the MB-01 colorectal adenoma clinical research study, sequencing technology and microbiome diagnostics platform.
Human Microbiome is the current project in Research field. The importance of Microorganisms in the human body, the importance and novel roe of the microorganisms on a human body is very effective and helpful. Fecal Transplantation is a unique and helpful technique to cure a dreadful disease naturally by means of microorganisms or introducing the normal flora in to the body again.
The Human Microbiome in Sports Performance and Healthctorgan
Because our knowledge of the human microbiome is moving so rapidly, we turned our presentation at this conference into a discussion session so experts in the audience could share their professional knowledge and personal experience. By the end of the session, it was clear that we had barely scratched the surface of the importance of our microscopic kin to our health, to sports performance, and to how we need to think about designing research studies. A list of recommended resources is available at: www.caroltorgan.com/microbiome-sports/. We welcome your input!
Looking for Microbiome Testing centers in Australia? Have you by any chance searched for Allele Microbiome? If not, you could certainly look them over.
Microbes are our Friends.. The effective way of microbes treating our diseases and fighting with the pathogens is very effective. The human microbiome project is a current topic the researchers are focusing now. We think we are humans but the research of Human Microbiome Project states that we are 1% Humans 99% microbes. The highlights of this project is fecal transplantation and effective way of killing pathogens with the positive microbes.
The way we treat our body will treat you back and the antigens which are entered in to our body will greatly fight with microbes to survive and make the human body safe and healthy.
Finally Microbes are us and we are them
Jonathan Eisen talk at #UCDavis 10/19/15 on "Microbiomes in Food and Agricult...Jonathan Eisen
Slides for talk on "Microbiomes in Food and Agriculture" by JonathanEisen - note - not all slides were used in talk. These were there to stimulate discussion ...
These slides explores in general the discovery of the human microbiome, and the important roles they play in our well-being. Humans have evolved to live with microbes, this symbiotic relationship is crucial. Humans are in fact 'supra-organisms' that exhibit both human and microbial traits.
Microbiome Diagnostics Platform for Microbiome Health and Colon Cancer Preven...Laura Berry
Presented at the 4th Microbiome R&D and Business Collaboration Forum: USA. To find out more, visit: www.global-engage.com
Greg Kuehn, President and COO of Metabiomics, presents the MB-01 colorectal adenoma clinical research study, sequencing technology and microbiome diagnostics platform.
Human Microbiome is the current project in Research field. The importance of Microorganisms in the human body, the importance and novel roe of the microorganisms on a human body is very effective and helpful. Fecal Transplantation is a unique and helpful technique to cure a dreadful disease naturally by means of microorganisms or introducing the normal flora in to the body again.
The Human Microbiome in Sports Performance and Healthctorgan
Because our knowledge of the human microbiome is moving so rapidly, we turned our presentation at this conference into a discussion session so experts in the audience could share their professional knowledge and personal experience. By the end of the session, it was clear that we had barely scratched the surface of the importance of our microscopic kin to our health, to sports performance, and to how we need to think about designing research studies. A list of recommended resources is available at: www.caroltorgan.com/microbiome-sports/. We welcome your input!
Looking for Microbiome Testing centers in Australia? Have you by any chance searched for Allele Microbiome? If not, you could certainly look them over.
Irritable Bowel Syndrome (IBS) and Fecal Microbiota Transplant. A new hope fo...Find Good Health
IBDs including irritable bowel syndrome (ibs) or ulcerative colitis (uc) are a set of diseases developing into an epidemic. The unusual and recent rise in these kind of diseases most notably on developed countries point to a recent and area specific etiology, not a better healthcare and diagnosis.
Recent researchs are pointing to a healthier immune system and intestinal flora in undeveloped countries' population and an imbalance in our gut flora caused by excessive use of antibiotics.
For more information about health and wellbeing visit our site at:
http://findgoodhealth.org/
A review report on detailed study of research endeavours, undertaken on Human Microbiome, its composition, its implications, applications, disease and other role.
Se realiza una revisión sobre los diversos mecanismos neuroendocrinos que ocurren en la madre y en el recién nacido, y que están relacionados con el inicio y consolidación del apego entre ambos. Se expone el papel que diferentes hormonas y neurotransmisores juegan en la regulación del vínculo en relación con el parto, el postparto inmediato y la lactancia. La interferencia en el inicio del apego entre madre e hijo puede tener potenciales efectos a largo plazo en el comportamiento y en el afecto del recién nacido. La influencia que determinados aspectos relacionados con el parto (como la realización de una cesárea electiva, la administración de hormonas durante el parto, el nacimiento prematuro, la separación madre-hijo o la alimentación mediante biberón) puedan tener sobre el mecanismo neuroendocrino del vínculo y sus consecuencias son objeto de esta revisión
16/03/2015 Seminario VHIR
Dr. Sergio Sosa-Estani. Director del Instituto Nacional de Parasitología "Dr. Mario Fatala Chabén", investigador del Consejo Nacional de Investigaciones Científicas y Técnicas (Conicet). Buenos Aires, Argentina.
Director del Instituto Nacional de Parasitología-Dr. Mario Fatala Chaben en Argentina. El instituto está involucrado en un extenso programa de investigación, incluso como un referente regional en el diagnóstico, prevención y control de enfermedades prevalentes y emergentes en Argentina, tales como la enfermedad de Chagas, Leishmaniasis y otras.
Sosa-Estani desempeñó como director de la Unidad de Vector Borne de Control de Enfermedades del Ministerio de Salud de Argentina. Tiene más de 50 publicaciones a su nombre, y es el investigador principal o co-investigador en diez proyectos de investigación en curso o finalizados.
Profiling Hospital-Acquired Pathogens and Antibiotic Resistance Genes WebinarQIAGEN
Hospital-acquired infections (HAIs) are caused by bacterial, viral and fungal pathogens that easily spread through the body. The most common HAIs include urinary tract infections, bloodstream infections and pneumonia. HAIs are becoming more virulent and more resistant to the antibiotics typically used to fight them, making antibiotic resistance a serious public health concern. In this webinar, we will provide an overview of hospital-acquired pathogens and antibiotic resistance. We will also present tools to help you identify and characterize hospital-acquired bacterial species and antibiotic resistance genes in your research samples.
Microbial Pathogenesis and Host Immune ResponseQIAGEN
The research community has begun correlating the makeup of individual microbiomes with disorders and diseases such as obesity, atherosclerosis and cancer. To accomplish this, researchers must first identify and characterize these microbial communities and understand the complex immune interactions between host and pathogen. This webinar provides you with a complete overview of the microbiome, metagenomics and host-pathogen interactions. Experimental strategies, from sample to insight, which can facilitate your microbiology and immunology research, are highlighted.
The differences between a cow and a monkey are clear. It is easy to tell a moth from a mosquito. So why are there still scientific studies that mix them up? The answer is simple: hundreds of cell lines stored and used by modern laboratories have been wrongly identified. Some pig cells are labelled as coming from a chicken; cell lines advertised as human have been shown to contain material from hamsters, rats, mice and monkeys. Problems have already been found with more than 400 cell lines. (Cited from Nature 520 (2015)).
An increasing number of scientific publications (i.e. Nature journals) are now sistematically asking for cell line authentication at the moment of paper submission. To help researchers to meet this requirement, UAT is starting to offer a new service for human cell line authentication.
The Gut-Brain Connection: An Inside Look at DepressionAugustin Bralley
During a recent Metametrix sponsored breakfast at the IFM Symposium in Hollywood, Florida, Dr. Todd LePine gave a compelling presentation entitled The Gut-Brain Connection: An Inside Look at Depression.
Trillions of bacteria, viruses, parasites and fungi live in and around our bodies. Together, they make up the microbiome, which has been called the largest organ in the human body and been linked to a range of health issues, from asthma to diabetes to inflammatory bowel disease to obesity. Paul Kubes and Kathy McCoy, professors at UCalgary’s Cumming School of Medicine and researchers at the Western Canadian Microbiome Centre, share the science of the microbiome and why it holds the key to better health for all of us. Watch the full webinar at http://www.ucalgary.ca/explore/microbiome-why-few-trillion-germs-can-be-good-thing
Foodborne Pathogens: Where Have We Been and Where Are We Going? dedmark
Presented at 2013 Arkansas Association for Food Protection annual conference.
Michael G. Johnson, Ph.D.
Emeritus Professor, University of Arkansas Food Science Department
In the race towards exams, it can be easy to forget the other goals of science education: scientific literacy (science in life) and STE(A)M careers (science in society).
CONNECT is an EC-funded project offering a new kind of resource, called a Science Action.
It’s a set of activities to integrate a real-life challenge into an existing topic and it ticks lots of boxes:
Engage with a real-life challenge
Know and apply a science concept
Practice an enquiry skill
Understand how science affects their world
Interact with a scientist or engineer ( CONNECT Platform)
Talk about science with family-members
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
36. 9 teens with Crohn’s had
fecal microbiome transplants
(gut bacteria from a healthy donor)
7 of them were in remission
after 2 weeks
5 were still in remission
after 12 weeks