Domains of unknown function are essential in yeast Data-driven design of cell factories and communities Synthetic Biology via programmable directed evolution Illuminating the druggable genome and the quest for new drug targets Machine reading for cancer biology 3decision®: Bringing structural data analytics to the masses Network-driven drug discovery: A computational network biology approach to drug discovery Measuring project success and Shannon's maxim: the enemy knows the system The Largest General Translational Informatics Public Private Partnership to Date The challenges of Analytical Data Management in R&D Will data scientists lead the discovery of cancer therapeutics? Improving exome sequencing, targeted sequencing, and low frequency variant detection Population scale sequencing by cost-efficient targeted NGS Disease interpretation of whole genome sequence variants Targeting giants - the pharmacology of adhesions GPCRs