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UTERINE
ABNORMALITIES
SUBMITTED
BY
Ms. Ashima Singh
Bsc. Nursing 4th
year
CONTENT
 INTRODUCTION
 DEFINITION
 INCIDENCE
 ETIOLOGY
 CLASSIFICATION OF UTERINE ABNORMALITIES
 DIAGNOSTIC MEASURES
 COMPLICATION
 MANAGEMENT
INTRODUCTION
A Uterine abnormalities are malformations of the uterus that develop
during embryogenic life. Uterine abnormalities occur in less then 5%
of all women, but have been noted in upto 25% of women who have
had miscarriages and/or deliveries of premature babies.
When a women is in her mother’s womb, her uterus develops as to
separate halves that fuse together before she is born. When a
womens uterus develops differently from most women, it is called
uterine anomaly.
DEFINITION
 A uterine abnormalities is a type of female genital malformation
resulting from an abnormal development of Mullerian ducts during
embryogenesis.
 Symptoms range from amenorrhoea, infertility, recurrent pregnancy
loss, and pain, to normal functioning depending on the nature of the
defect.
INCIDENCE
The prevalence of uterine malformation is
estimated to be 6.7% in the general
population, slightly higher 7.3% in the
infertility population, and significantly higher
in a population of women with the history of
recurrent miscarriages ( 16%).
 Prevalence in general
population 1 in 201 (0.5%)
 Distribution : 7% arcuate, 34%
septate, 39% bicornuate, 11%
didelphic, 5% unicornuate, 4%
hypoplastic and other forms.
h
y
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o
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a
s
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ETIOLOGY
1.Genetic cause
2.No any other causes at this time is
present
TYPES
 AMERICAN FERTILITY SOCIETY
CLASSIFICATION----
 Class 1: Hypoplasia uterus or Agenesis:
Segmental or complete (absent uterus).
 Class2: Unicornuate uterus with or
without rudimentary horn (a one-
sided uterus).
 Class3: Didelphus uterus also uterus
didelphis (double uterus) .
 Class4: Bicornuate uterus: Complete or
partial ( uterus with two horns).
 Class5: Septate uterus: Complete or partial
(uterine septum or partition).
 Class6: Arcuate uterus: There is a concave
dimple in the uterus fundus within the cavity.
 Class7: Des related uterus: The uterine
cavity has a “t-shaped” as a result of fetal
exposure to diethylstilbestrol.
o CLASS 1: VAGINAL AGENESIS/
HYPOPLASIA--
It is characterised by an absence or
hypoplasia of the uterus, proximal
vagina and sometimes the fallopian
tube.
 Diagnosed at the age of 15-18 yr
 Assessment and physical
examination
 Treatment : Surgical correction-
Plastic surgery
• o CLASS 2: UNICORNUATE
UTERUS--
• The unicornuate uterus forms
when one mullerian duct fail to
elongated but the another one
develops normally.
• TREATMENT:
• No surgical intervention is
required unless endometrial
tissue in a rudimentary horn
results in pain or a pelvic mass or
unless an incompetent cervix is
suspected during pregnancy.
o CLASS 3: DIDELPHUS UTERUS--
It is a rare congenital anomaly and is a
consequence of unilateral or bilateral
mullerian duct duplication.
It’s exact cause is unknown but it is
generally present from birth, though
often becomes noticeable after
puberty .
Diagnosis is carried out using a
physical examination alongside USG
and 3D USG more recently.
There is no treatment as such for the
condition, but it must be managed
especially during pregnancy.
o CLASS 4: BICORNUATE
UTERUS—
When the mullerians duct fuse
incompletely at the level of the
fundus then bicornuate formed.
The lower uterus and cervix are
completely fused resulting in 2
separate but communicating
endometrial cavities with a single
cervix and vagina.
 Pre-term birth: The rate of
preterm delivery is 15 to 25%.
 A pregnancy may not be
reach full term in a
bicornuate uterus when the
baby begins to grow in either
o CLASS 5: SEPTATE
UTERUS—
 Most common form of
mullerian duct defect .
 From incomplete
resorption of the medial
septum after the
complete fusion of the
mullerian duct has
occurred.
 It is not considered
necessary to remove a
septum that has not
caused problems,
especially in women
who are not considering
pregnancy.
ARCUATE UTERUS
 Characterised by a small septate indentation
the superior aspect of the uterine cavity in the
fundus.
 Many patient with an arcuate uterus will not
experience any reproductive problems and do
not require any surgery. In patients with
recurrent
pregnancy loss thought to be caused by an
arcuate uterus hysteroscopic resection can be
performed.
O CLASS 7: DES RELATED
ANOMALIES—
 DES is a synthetic
estrogen that was
prescribed to women for
recurrent miscarriage and
premature delivery
during the year 1940-
early 1970.
 The uterine cavity has a “T-
shape” as a result of fetal
exposure to
diethylstilbestrol.
CLINICAL FEATURES
 No any symptoms
 Difficulty in getting pregnant
 Pelvic pain
 Dysmenorrhea
 Uterine rupture during pregnancy
 Recurrent pregnancy loss
 Concurrent renal abnormalities
 Imperforated hymen
DIAGNOSTIC MEASURES
COMPLICATION
I. Infertility
II. Early pregnancy loss
III. Uterine rupture due to its poor development
IV. Malpresentations
V. Prolonged obstructed labor
VI. Abortion
VII. Weak uterine action
MANAGEMENT
1. No non-surgical treatment is present only symptomatic
treatment is done.
2. Surgical intervention is considered when a septate uterus is found.
3. Bicornuate, unicornuate and didelphic uteri rarely require surgical
management.
BIBLIOGRAPHY
 WWW.WIKIPEDIA.NET
 WWW.SLIDESHARE.COM
uterine abnormality

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uterine abnormality

  • 2. CONTENT  INTRODUCTION  DEFINITION  INCIDENCE  ETIOLOGY  CLASSIFICATION OF UTERINE ABNORMALITIES  DIAGNOSTIC MEASURES  COMPLICATION  MANAGEMENT
  • 3. INTRODUCTION A Uterine abnormalities are malformations of the uterus that develop during embryogenic life. Uterine abnormalities occur in less then 5% of all women, but have been noted in upto 25% of women who have had miscarriages and/or deliveries of premature babies. When a women is in her mother’s womb, her uterus develops as to separate halves that fuse together before she is born. When a womens uterus develops differently from most women, it is called uterine anomaly.
  • 4. DEFINITION  A uterine abnormalities is a type of female genital malformation resulting from an abnormal development of Mullerian ducts during embryogenesis.  Symptoms range from amenorrhoea, infertility, recurrent pregnancy loss, and pain, to normal functioning depending on the nature of the defect.
  • 5. INCIDENCE The prevalence of uterine malformation is estimated to be 6.7% in the general population, slightly higher 7.3% in the infertility population, and significantly higher in a population of women with the history of recurrent miscarriages ( 16%).  Prevalence in general population 1 in 201 (0.5%)  Distribution : 7% arcuate, 34% septate, 39% bicornuate, 11% didelphic, 5% unicornuate, 4% hypoplastic and other forms. h y p o p l a s t i c u n i c
  • 6. ETIOLOGY 1.Genetic cause 2.No any other causes at this time is present
  • 7. TYPES  AMERICAN FERTILITY SOCIETY CLASSIFICATION----  Class 1: Hypoplasia uterus or Agenesis: Segmental or complete (absent uterus).  Class2: Unicornuate uterus with or without rudimentary horn (a one- sided uterus).  Class3: Didelphus uterus also uterus didelphis (double uterus) .  Class4: Bicornuate uterus: Complete or partial ( uterus with two horns).  Class5: Septate uterus: Complete or partial (uterine septum or partition).  Class6: Arcuate uterus: There is a concave dimple in the uterus fundus within the cavity.  Class7: Des related uterus: The uterine cavity has a “t-shaped” as a result of fetal exposure to diethylstilbestrol.
  • 8. o CLASS 1: VAGINAL AGENESIS/ HYPOPLASIA-- It is characterised by an absence or hypoplasia of the uterus, proximal vagina and sometimes the fallopian tube.  Diagnosed at the age of 15-18 yr  Assessment and physical examination  Treatment : Surgical correction- Plastic surgery
  • 9. • o CLASS 2: UNICORNUATE UTERUS-- • The unicornuate uterus forms when one mullerian duct fail to elongated but the another one develops normally. • TREATMENT: • No surgical intervention is required unless endometrial tissue in a rudimentary horn results in pain or a pelvic mass or unless an incompetent cervix is suspected during pregnancy.
  • 10. o CLASS 3: DIDELPHUS UTERUS-- It is a rare congenital anomaly and is a consequence of unilateral or bilateral mullerian duct duplication. It’s exact cause is unknown but it is generally present from birth, though often becomes noticeable after puberty . Diagnosis is carried out using a physical examination alongside USG and 3D USG more recently. There is no treatment as such for the condition, but it must be managed especially during pregnancy.
  • 11. o CLASS 4: BICORNUATE UTERUS— When the mullerians duct fuse incompletely at the level of the fundus then bicornuate formed. The lower uterus and cervix are completely fused resulting in 2 separate but communicating endometrial cavities with a single cervix and vagina.  Pre-term birth: The rate of preterm delivery is 15 to 25%.  A pregnancy may not be reach full term in a bicornuate uterus when the baby begins to grow in either
  • 12. o CLASS 5: SEPTATE UTERUS—  Most common form of mullerian duct defect .  From incomplete resorption of the medial septum after the complete fusion of the mullerian duct has occurred.  It is not considered necessary to remove a septum that has not caused problems, especially in women who are not considering pregnancy.
  • 13. ARCUATE UTERUS  Characterised by a small septate indentation the superior aspect of the uterine cavity in the fundus.  Many patient with an arcuate uterus will not experience any reproductive problems and do not require any surgery. In patients with recurrent pregnancy loss thought to be caused by an arcuate uterus hysteroscopic resection can be performed.
  • 14. O CLASS 7: DES RELATED ANOMALIES—  DES is a synthetic estrogen that was prescribed to women for recurrent miscarriage and premature delivery during the year 1940- early 1970.  The uterine cavity has a “T- shape” as a result of fetal exposure to diethylstilbestrol.
  • 15. CLINICAL FEATURES  No any symptoms  Difficulty in getting pregnant  Pelvic pain  Dysmenorrhea  Uterine rupture during pregnancy  Recurrent pregnancy loss  Concurrent renal abnormalities  Imperforated hymen
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  • 21. COMPLICATION I. Infertility II. Early pregnancy loss III. Uterine rupture due to its poor development IV. Malpresentations V. Prolonged obstructed labor VI. Abortion VII. Weak uterine action
  • 22. MANAGEMENT 1. No non-surgical treatment is present only symptomatic treatment is done. 2. Surgical intervention is considered when a septate uterus is found. 3. Bicornuate, unicornuate and didelphic uteri rarely require surgical management.