The document discusses Newton's three laws of motion. It begins by defining key terms like force, inertia, and acceleration. It then explains each of Newton's three laws: (1) an object at rest stays at rest and an object in motion stays in motion unless acted upon by an unbalanced force, (2) acceleration is directly proportional to force and inversely proportional to mass, and (3) for every action there is an equal and opposite reaction. Examples are provided to illustrate Newton's laws, such as how gravity causes free fall acceleration. Balanced and unbalanced forces are also distinguished.
Hi! I am Shaira Gee Freesha Tajan and thjs captivating presentation is about the Factors Affecting Potential and Kinetic Energy. My presentation helps you to understand and not be perplexed about the difference of potential and kinetic energy. Please like my presentation :)
Unit I: Force, Motion and Energy
Module 2 – Work and Energy
· Definition and Calculation of Work
· Kinetic Energy
· Potential Energy
· Work, Energy and Power Relations
Unit I: Force, Motion and Energy
Module 3 – Heat and Temperature
· Heat vs. Temperature
· Effects on Matter (Phase Change)
· Heat Capacity
· Temperature Conversion
Sound is produced when a matter vibrates. Sounds consists waves and these waves travel as a longitudinal waves. Sound travels fastest in solids because the particles are closer. The speed of sound depends on the temperature of matter. The higher the temperature, the higher the speed of sound is. The properties of sound are reflection and refraction. In reflection, the sound wave turns back when it hits a barrier. A good example of this are echoes and reverberations. On the other hand, refraction is the bending of sound waves.
Hi! I am Shaira Gee Freesha Tajan and thjs captivating presentation is about the Factors Affecting Potential and Kinetic Energy. My presentation helps you to understand and not be perplexed about the difference of potential and kinetic energy. Please like my presentation :)
Unit I: Force, Motion and Energy
Module 2 – Work and Energy
· Definition and Calculation of Work
· Kinetic Energy
· Potential Energy
· Work, Energy and Power Relations
Unit I: Force, Motion and Energy
Module 3 – Heat and Temperature
· Heat vs. Temperature
· Effects on Matter (Phase Change)
· Heat Capacity
· Temperature Conversion
Sound is produced when a matter vibrates. Sounds consists waves and these waves travel as a longitudinal waves. Sound travels fastest in solids because the particles are closer. The speed of sound depends on the temperature of matter. The higher the temperature, the higher the speed of sound is. The properties of sound are reflection and refraction. In reflection, the sound wave turns back when it hits a barrier. A good example of this are echoes and reverberations. On the other hand, refraction is the bending of sound waves.
This presentation is about the basic concepts of food and nutrition, history of nutrition in the world and India and role of health care professional in Nutrition
Newton's First Law of Motion: I. Every object in a state of uniform motion tends to remain in that state of motion unless an external force is applied to it. This we recognize as essentially Galileo's concept of inertia, and this is often termed simply the "Law of Inertia".
The Law of Inertia (The 3 Laws of Motion).pptRose Alba
What is the meaning of law of inertia?
The law of inertia states that an object or mass will remain either at rest or in motion in the same direction, unless acted upon by an unbalanced force. This also means that the more massive an object is, the more difficult it is to influence its velocity.
The Laws of Motion, formulated by Sir Isaac Newton, stand as the cornerstone of classical mechanics, providing a fundamental framework for understanding the motion of objects. Introduced in Class 11 physics curriculum, these laws elucidate the relationship between the motion of an object and the forces acting upon it. Newton's First Law, often termed the Law of Inertia, sets the stage by describing the natural tendency of objects to remain at rest or in uniform motion unless influenced by external forces. The Second Law establishes a quantitative link, defining how the acceleration of an object is directly proportional to the net force applied and inversely proportional to its mass. Finally, the Third Law introduces the concept of action and reaction, emphasizing that every force exerted by one object is met with an equal and opposite force from another. As students delve into these laws, they uncover a comprehensive understanding of the principles governing the dynamics of the physical world.
For more information, visit. www.vavaclasses.com
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
2. LEARNING COMPETENCIES:
The Learners should be able to…
1. investigate the relationship between the amount of force applied
and the mass of the object to the amount of change in the object’s
motion; S8FE-Ia-15
2. infer that when a body exerts a force on another, an equal
amount of force is exerted back on it; S8FE-Ia-16
3. demonstrate how a body responds to changes in motion;
S8FE-Ib-17
4. relate the laws of motion to bodies in uniform circular motion;
S8FE-Ib-18
5. infer that circular motion requires the application of constant
force directed toward the center of the circle; S8FE-Ib-19
5. FORCE
A PUSH OR PULL ON A BODY IS CALLED FORCE.
FORCES ARE USED IN OUR EVERYDAY ACTIONS LIKE
PUSHING, PULLING, LIFTING, STRECHING, TWISTING
AND PRESSING.
6. EFFECTS OF FORCE
• A force cannot be seen. A force can be judged only by the
effects which it can produce in various bodies (or objects)
around us.
1. A force can move a stationary body.
2. A force can stop a moving body.
3. A force can change the speed of a moving body.
4. A force can change the direction of a moving body.
5. A force can change the shape and size of a body.
7. Questions:
1.What makes objects move the way they
do?
2.Why do objects move in different ways?
Why are some objects faster than the
others?
3.What makes objects stay in place?
-
8. Activity 1 Forces on objects at rest
Q1. Is the pen at rest or in motion?
Ans. The pen is at rest
Q2.Are the forces acting on the pen? If yes, draw
the forces.You may use arrows to represent
these forces.
Ans. The forces acting on the pen are tension
force(force exerted by the string on the pen) and
force of gravity
9. Q3 What happens to the pen? What could
have caused the pen’s motion?
Ans. When the string was cut, the pen falls
to the ground.The force of gravity makes the
object fall down.
Q4. Is the book at rest or in motion?
Ans. The book is at rest
10. Q5 Are there forces acting on the book? If yes,
draw the forces acting on the book.
Ans. Yes The forces acting on the book are the
force exerted by the table on the book(Normal
Force) and force of gravity
Q6 Did the book move? How will you make the
book move?
Ans. No.The book is at rest.The book maybe
moved by pushing it on one side only.
11.
12.
13. ACTIVITY 2
RECOGNIZING FORCES
ACTIVITY 3
CHANGES BROUGHT ABOUT BY FORCES
ACTIVITY 4
MAKING AN OBJECT MOVE
SELF TEST
ACTIVITY 5
DIFFERENT TYPES OF FORCES
14. Key Concepts
FORCE-push or a pull that can make an
object moves
. -can make objects move,move
faster,stop or change their direction of
motion.
-change the shape of things
-are described in terms of the
properties such asmagnitude,
direction,point of application and line
of action.
15. Magnitude-refers to the size or strength of the force
and commonly expressed in Newton.( 5N,3N)
Direction of the arrow-direction of the force.
Length of the arrow-represents the relative
magnitude of the force.
If the force of an object increased,the length of the
arrow also increases.
Line of Action-is the straight line passing through the
point of application.
Point of Application-is parallel to the direction of the
force.
16. • If an object stays at rest, there are forces
acting upon it.
• Hanging objects have tension force and
force of gravity acting on them
• Objects at rest have normal force and
force of gravity acting on them
• Tension Force-Force exerted by the string
on the object
17. • Normal Force is the upward force
perpendicular to the surface of contact
between two bodies
19. Balanced vs. unbalanced forces
• Unbalanced: when the net force on
an object is not zero. These
produce a change in motion.
• Balanced: when the net force on an
object equals zero. These do NOT
produce change in motion.
20. Balanced Force-the forces acting on an
object are equal in magnitude but
opposite in direction.
-lie along the same line of action.
-the object either stays at rest or
continues to move at constant velocity.
21. Friction-acts opposite the
direction of motion.
-slows down/resists the
motion of an object.
Due to unbalanced force, the object
change its state of motion hence we say
that it accelerates or increase in velocity
but it can also decelerate or decrease in
velocity.
24. Some tips:
1. Forces in the same direction- add the two
forces together.
+ =
1. Forces in different directions- subtract
the two and figure out which direction was
the stronger of the two.
- =
25. To determine the net force,use the algebraic
signs + and – to indicate the directions of
forces.
Fnet=F1 + F2 +……(if the forces of an object
are in the same direction)
Fnet= F1-F2-…….(if the forces of an
object are in opposite direction)
27. OBJECTIVES:
a. State and Explain Newton’s three
laws on motion
b. Explain the concept of inertia and
give examples
c. Apply the Laws of Motion to simple
situations
d. Solve problems using the second
law of motion
e. Differentiate forces related to Law
of Interaction and Forces in a
Balanced state
28. NEWTON’S LAW OF MOTION
• NEWTON HAS GIVEN THREE LAWS
OF TO DEFINE THE MOTION OF
BODIES. THESE LAWS ARE KNOWN
AS NEWTON’S LAWS OF MOTION.
29. Sir Isaac Newton-one of the
greatest scientists and
mathematicians, he formulated
the laws regarding motion and
forces.
1.Law of Inertia
2.Law of Acceleration
3. Law of Interaction
30. NEWTON’S FIRST LAWOF MOTION
-an object at rest will
remain at rest or an
object in motion will
stay in motion and
travel in straight line
unless acted upon by an
external net or
unbalanced force.
31. Newton’s First Law (law of inertia)
• Mass (kg)is the measure of the
amount of matter in an object.
• INERTIA is a property of an object
that describes how much it will
resist change to the motion of the
object
32. Inertia-a property of an object to
resist any change in its state of
motion.
More massive object which has more
inertia is more difficult to move from
rest,slow down,speed up or change
its direction.
36. Force is expressed in Newton (N).
1N=1kg.m/s2.
The SI Unit for acceleration if
m/s2(meter per second square),
for mass is kg(kilogram) and for
force is Newton(N).
37. If the acceleration of an
object increases, the force of
it also increases.
If the acceleration of an
object decreases, the force of
it also decreases.
38. If the acceleration of an
object increases, the mass of
it decreases.
If the acceleration of an
object decreases, the mass of
it increases.
40. Freefall and Second Law of Motion.
Galileo-found out that two bodies
dropped at the same height will reach
the ground at the same time regardless
of their masses.
(without air resistance).
Aristotle-he proved the observation of
Galileo in the Leaning Tower of Pisa.
41. Gravity-acts on all objects on the
earth’s surface and causes them to
accelerate when released.This is known
as the acceleration due to gravity
and it is equal to 9.8m/s2.
42. Freefall and Second Law of Motion.
Galileo-found out that two bodies dropped at the same height
at the same height will reach the ground
at the same time regardless of their masses.(without
air resistance).
Aristotle-he proved the observation of Galileo in the Leaning
Tower of Pisa.
Gravity-acts on all objects on the earth’s surface and causes
them to accelerate when released.This is known as the
acceleration due to gravity and it is equal to 9.8m/s2.
43. Circular Motion and Second Law of Motion
Circular Motion-motion of an object along a circle.
2 Forces in a Circular Motion
1.Centripetal Force-the inward force the pulls the
object towards the center of the circle.
2.Centrifugal Force-the outward force the pulls the
object away the center of the circle.
44. NEWTON’S THIRD LAWOF MOTION
Whenever one body exerts a force on another body,
the second body exerts equal and opposite force to
the first body. OR,
To every action there is equal and opposite reaction.
1. EX: the rocket works on the principal of action
and reaction.
2. When a bullet is fired from the gun, a force
sending the bullet forward is equal to the force
sending the gun backward. But due to high mass
of the gun, it moves only a little distance
backward and gives jerk.
45. Newton’s 3rd Law
• For every action there is an equal and opposite
reaction.
Book to
earth
Table to
book
46. Think about it . . .
What happens if you are standing on a skateboard or
a slippery floor and push against a wall? You slide in
the opposite direction (away from the wall), because
you pushed on the wall but the wall pushed back on
you with equal and opposite force.
Why does it hurt so much when you stub your toe?
When your toe exerts a force on a rock, the rock
exerts an equal force back on your toe. The harder
you hit your toe against it, the more force the rock
exerts back on your toe (and the more your toe
hurts).
47. Action: earth pulls on you
Reaction: you pull on earth
Action and Reaction on Different Masses
Consider you and the earth
52. Action-Reaction Forces Balanced Forces
Two forces are equal in size
Two forces are opposite to each
other in terms of direction.
Two forces have the same line of
action
Action acts on one object,while
reaction acts on another object.
Two forces are equal in size
Two forces are opposite to
each other in terms of
direction.
Two forces act along the
same line of action
Two forces act upon the
same object
Differences between forces related to
Law of Interaction and Forces in a Balanced state: