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Epilepsy or Narcolepsy? AskTheNeurologist.Com Author Anon
History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sleep attacks ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Past History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Examination ,[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object]
Background 26/8
“ Drowsy” 26/8
Impression following EEG ,[object Object],[object Object],[object Object],[object Object]
Course ,[object Object],[object Object],[object Object],[object Object]
Concept of V-waves ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
EEG tip ,[object Object],[object Object]
 
“ Drowsy” 26/8
Coronal 26/8 drowsy
Coronal 26/8 low amplitude
Follow-up EEG 28/8
DD ,[object Object],[object Object],[object Object]
Tiredness before LOC Episodes of LOC coincide with v-waves and no other epileptic activity A focus near Cz would be associated with focal seizures of leg ? Tongue biting ? Response to anti-epileptic medications Epilepsy Too severe Recurrence following discharge with adequate sleep History of sleep deprivation Sleep deprivation No other features Age of onset EDS Sleep attacks Narcolepsy Against For
 
Excessive daytime sleepiness / hypersomnia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Aspects of REM sleep intrude into wakefulness ,[object Object],[object Object],[object Object]
Hypnagogic hallucinations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sleep paralysis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cataplexy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lab. Findings ,[object Object],[object Object]
Polysomnography ,[object Object],[object Object],[object Object],[object Object],[object Object]
MSLT ,[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosing Narcolepsy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Secondary causes of narcolepsy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Genetics of narcolepsy ,[object Object],[object Object],[object Object]
Role of orexin ( hypocretin) ,[object Object],[object Object]
Brown = Tyr OH’lase staining of Locus Coerulius neuron Black = terminals immunoreactive for orexin
Evidence for orexin hypothesis ,[object Object],[object Object],[object Object],[object Object]
 
Cataplexy and Sleep paralysis:-  ,[object Object],[object Object],[object Object],[object Object]
Sleep paralysis = opposite problem i.e. in RBD lose the protective paralysis which is inappropriately active in sleep paralysis and cataplexy.
 
 
Features of RBD ,[object Object],[object Object]
RBD associations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Epilepsy Vs Narcolepsy