With the world's highest deaths due to accidents, we really need to take the cause up on a war footing. And who better to benefit from it but an insurance brand?
Why, When and How Do I Start a Digital Transformation?Acquia
Presented at Acquia Engage APAC by Brittany Fox, Marketing Campaign Strategist, Deloitte.
Every organisation undergoing a marketing transformation has a starting point, with the difference only being the product of internal capability and maturity. At Deloitte, we take our clients from their starting point to being ready for whatever the next innovation is. This is the only real mechanism enterprises can implement for the future.
Digital Transformation Strategy & Framework | By ex-McKinseyAurelien Domont, MBA
Go to www.slidebooks.com to Download and Reuse Now a Digital Transformation Strategy & Framework in Powerpoint | Created By ex-McKinsey & Deloitte Strategy Consultants.
Digital Transformation - Beyond the Hype #DF13Capgemini
While there is increased recognition of digital’s role, the challenge remains for many to translate it into business value through innovation and competitive advantage. They are caught struggling for pace, and risk falling into the chasm between initiation and termination of transformation initiatives. Didier Bonnet's shares Capgemini Consulting's insight at Dreamforce '13 into the results of the landmark study with MIT on transformation trends, along with insight from an expert customer panel that will share experiences on how they address these challenges. This is the slide deck accompanying the session in San Francisco.
Why, When and How Do I Start a Digital Transformation?Acquia
Presented at Acquia Engage APAC by Brittany Fox, Marketing Campaign Strategist, Deloitte.
Every organisation undergoing a marketing transformation has a starting point, with the difference only being the product of internal capability and maturity. At Deloitte, we take our clients from their starting point to being ready for whatever the next innovation is. This is the only real mechanism enterprises can implement for the future.
Digital Transformation Strategy & Framework | By ex-McKinseyAurelien Domont, MBA
Go to www.slidebooks.com to Download and Reuse Now a Digital Transformation Strategy & Framework in Powerpoint | Created By ex-McKinsey & Deloitte Strategy Consultants.
Digital Transformation - Beyond the Hype #DF13Capgemini
While there is increased recognition of digital’s role, the challenge remains for many to translate it into business value through innovation and competitive advantage. They are caught struggling for pace, and risk falling into the chasm between initiation and termination of transformation initiatives. Didier Bonnet's shares Capgemini Consulting's insight at Dreamforce '13 into the results of the landmark study with MIT on transformation trends, along with insight from an expert customer panel that will share experiences on how they address these challenges. This is the slide deck accompanying the session in San Francisco.
Digital Transformation Solution Powerpoint Presentation SlidesSlideTeam
“You can download this product from SlideTeam.net”
Introducing Digital Transformation Solution PowerPoint Presentation Slides. Integrate modernized technology into all the areas of your business by making use of this digital change plan PPT template. Fundamentally change how you deliver value and operate in the marketplace. Challenge your status quo and conquer any difficulty by incorporating this business transformation PowerPoint presentation in the way your business functions. This topic-specific and extensively researched technology change PPT graphic will prove useful for business persons looking to adopt modern technology and implement it in their work culture. Additionally, it will help you add value to every customer interaction by using more technology. Furthermore, you can discuss the importance, core elements, barriers, way to achieve and other aspects of digital transformation by employing this technology change plan PowerPoint layout. Hence, download this professional and extremely useful transformation plan PowerPoint presentation now to facilitate technology change in your business operations. https://bit.ly/3pDZtaz
We will look at how some of the world's most well known brands are transforming themselves in collaboration with Pivotal.
Speaker: Faiz Parkar, Director EMEA GTM, Pivotal
When you hear “digital” most people start to think about Google, Facebook or other technology companies. But now transforming into a digital company is the strategic objective for many companies across multiple sectors. We see digitisation as the driving strategy for many global business; GE’s strategy is to become the first digital industrial company and is moving its headquarters to Boston to be closer to MIT (Massachusetts Institute of Technology). Deutsche Bank wants to transform into a digital bank, and Sephora is digitising the world of beauty. The transformation is not just how these companies manage clients and deliver services through the web and smart phone apps, but back office processes, enhancing organisational agility, speeding up supply chains and recreating whole service offerings to make life easier or better for clients.
7 Ways to Lead Digital Transformation Without Being an IT SpecialistVistage UK
SMEs should be embracing the digital transformation to grow their businesses. This slideshare shows how non-IT business leaders can use strategic thinking and leadership excellence to drive innovation and change.
Driving Business Innovation through Technology Innovationaccenture
Speed matters in a digital economy. Customers expect products and services to be instantly available through whatever channel they choose. New competitors are springing up with a different mind-set and path to seize market share and turn the value chain of an established company, or industry, on its head.
If agility accelerates growth, innovation is the driving force to achieve it. Business innovation is digital innovation driven by new ideas and advances in technology. As technology leaders, CIOs have a tremendous opportunity to be relentlessly proactive in identifying how technology can create new value for the business.
Leading Digital - Turning Technology into Business TransformationCapgemini
The annual festival of digital inspiration and innovation, hosted in Wales this week saw Capgemini partner with Welsh Government to showcase the Rural Payments Wales (RPW) project. As well as a stand demonstrating our solution, we also had a keynote by Cliff Evans and Matt Howell joined the panel session to discuss digital entrepreneurship. Capgemini were key sponsors; others included Accenture and Dell.
Profit and market value is migrating away from hardware, but few product companies are prepared and executing the required digital transformation. High tech companies need to invest in digital growth strategies, reinvigorate business models and create new revenue streams. Find out how to harness disruption to grow your business.
You can receive our Powerpoint slides by sharing this presentation and submitting your email at www.slidebooks.com | Digital Transformation Strategy Template and Training | By ex-Deloitte and McKinsey Consultants
Every organization needs to adapt to the ever-changing business environment. Sensing this need, we have come up with these content-ready change management PowerPoint presentation slides. These change management PPT templates will help you deal with any kind of an organizational change. Be it with people, goals or processes. The business solutions incorporated here will help you identify the organizational structure, create vision for change, implement strategies, identify resistance and risk, manage cost of change, get feedback and evaluation, and much more. With the help of various change management tools and techniques illustrated in this presentation design, you can achieve the desired business outcomes. This business transition PowerPoint design also covers certain related topics such as change model, transformation strategy, change readiness, change control, project managementand business process. By implementing the change control methods mentioned in the presentation, you will be able to have a smooth transition in an organization. So, without waiting much, download our extensively researched change management framework presentation. With our Change Management Presentation slides, understand the need for change and plan to go through it without any hassles.
Digital Transformation Solution Powerpoint Presentation SlidesSlideTeam
“You can download this product from SlideTeam.net”
Introducing Digital Transformation Solution PowerPoint Presentation Slides. Integrate modernized technology into all the areas of your business by making use of this digital change plan PPT template. Fundamentally change how you deliver value and operate in the marketplace. Challenge your status quo and conquer any difficulty by incorporating this business transformation PowerPoint presentation in the way your business functions. This topic-specific and extensively researched technology change PPT graphic will prove useful for business persons looking to adopt modern technology and implement it in their work culture. Additionally, it will help you add value to every customer interaction by using more technology. Furthermore, you can discuss the importance, core elements, barriers, way to achieve and other aspects of digital transformation by employing this technology change plan PowerPoint layout. Hence, download this professional and extremely useful transformation plan PowerPoint presentation now to facilitate technology change in your business operations. https://bit.ly/3pDZtaz
We will look at how some of the world's most well known brands are transforming themselves in collaboration with Pivotal.
Speaker: Faiz Parkar, Director EMEA GTM, Pivotal
When you hear “digital” most people start to think about Google, Facebook or other technology companies. But now transforming into a digital company is the strategic objective for many companies across multiple sectors. We see digitisation as the driving strategy for many global business; GE’s strategy is to become the first digital industrial company and is moving its headquarters to Boston to be closer to MIT (Massachusetts Institute of Technology). Deutsche Bank wants to transform into a digital bank, and Sephora is digitising the world of beauty. The transformation is not just how these companies manage clients and deliver services through the web and smart phone apps, but back office processes, enhancing organisational agility, speeding up supply chains and recreating whole service offerings to make life easier or better for clients.
7 Ways to Lead Digital Transformation Without Being an IT SpecialistVistage UK
SMEs should be embracing the digital transformation to grow their businesses. This slideshare shows how non-IT business leaders can use strategic thinking and leadership excellence to drive innovation and change.
Driving Business Innovation through Technology Innovationaccenture
Speed matters in a digital economy. Customers expect products and services to be instantly available through whatever channel they choose. New competitors are springing up with a different mind-set and path to seize market share and turn the value chain of an established company, or industry, on its head.
If agility accelerates growth, innovation is the driving force to achieve it. Business innovation is digital innovation driven by new ideas and advances in technology. As technology leaders, CIOs have a tremendous opportunity to be relentlessly proactive in identifying how technology can create new value for the business.
Leading Digital - Turning Technology into Business TransformationCapgemini
The annual festival of digital inspiration and innovation, hosted in Wales this week saw Capgemini partner with Welsh Government to showcase the Rural Payments Wales (RPW) project. As well as a stand demonstrating our solution, we also had a keynote by Cliff Evans and Matt Howell joined the panel session to discuss digital entrepreneurship. Capgemini were key sponsors; others included Accenture and Dell.
Profit and market value is migrating away from hardware, but few product companies are prepared and executing the required digital transformation. High tech companies need to invest in digital growth strategies, reinvigorate business models and create new revenue streams. Find out how to harness disruption to grow your business.
You can receive our Powerpoint slides by sharing this presentation and submitting your email at www.slidebooks.com | Digital Transformation Strategy Template and Training | By ex-Deloitte and McKinsey Consultants
Every organization needs to adapt to the ever-changing business environment. Sensing this need, we have come up with these content-ready change management PowerPoint presentation slides. These change management PPT templates will help you deal with any kind of an organizational change. Be it with people, goals or processes. The business solutions incorporated here will help you identify the organizational structure, create vision for change, implement strategies, identify resistance and risk, manage cost of change, get feedback and evaluation, and much more. With the help of various change management tools and techniques illustrated in this presentation design, you can achieve the desired business outcomes. This business transition PowerPoint design also covers certain related topics such as change model, transformation strategy, change readiness, change control, project managementand business process. By implementing the change control methods mentioned in the presentation, you will be able to have a smooth transition in an organization. So, without waiting much, download our extensively researched change management framework presentation. With our Change Management Presentation slides, understand the need for change and plan to go through it without any hassles.
An MBA dissertation assessing how effective the Leicester Fire and Rescue Service Diva Fire Safety initiative was in reducing fire incidences by reaching out to the Hindu Asian community of Leicester
Triumvirate Environmental's marketing team created a campaign in honor of National Safety Month. This presentation inspects the new tactics tested in this campaign, the results they produced and the plan moving forward.
In the framework of the implementation of Task 6 of the Project: Modernization and Safety Improvements of the Road Network in Ukraine – Technical Assistance
Smartphone Travel App Business Plan MBA ThesisAlexHoskinson
A summary of the findings of my MBA thesis for the Corvinus University of Budapest. The purpose of the thesis was to evaluate the need for a smartphone tour guide app, and then create a feasible business plan to create and introduce the product. The official title is "A Business Plan for a Mobile Travel Application that provides Guided Walking Experiences on Smartphones."
2014 is the Year of Media Complexity in the Government Sector
According to the findings from the 2014 Federal Media and Marketing Study (FMMS), government decision-makers are accessing information through an increasingly complex mixture of print, digital, mobile and social media.
In addition, mobility has become a major influencer on how government executives consume information – dramatically changing reading habits and reinforcing the need for government contractors to develop highly comprehensive strategies for influencing federal decision-makers.
Founded in 2008, Edge Marketing Services is a young, enthusiastic and talented team of professionals that help provide strategic counsel, creative solutions and timely responsive services.
In today’s world, with the new age media growing; we’ve expanded our horizons that focuses on our foremost service –Digital Marketing.
UAE has around 9 million internet population. Digital marketing is rapidly growing to become the future of marketing. At Edge Marketing Services, we’ll help your business adapt this new world that helps connect your consumers directly via websites, social media channels, campaigns, email marketing, online ads and integrated BTL activities.
For more details: http://bit.ly/10cOjd9
We don’t make brands, we build them! Contact us, we surely won’t disappoint you.
A sound and deep insight into building a sustainable DAO. All copyrights rest with Arca, published here for sharing knowledge and to keep as public memory.
NFT or Non-fungible tokens
Are identified as a unit of data stored in an electronic
ledger (blockchain technology), then validated to be a unique identifier that cannot be interchanged and are indivisible.
NFTs have bridged the gap between celebrities and fans, creators and collectors. A marketplace plays a very important role in the circulation of NFTs among every NFT enthusiast.
What is an NFT marketplace?
An NFT marketplace is a platform that acts as a medium or a meeting point for collectors and creators. Creators can come, list their NFTs on the marketplace. Whereas, for collectors, all they have to do is to come, bid, and buy their favorite NFT. Through this process, they come a step closer to their favorite celebrities, artists, or creators. For creators, it is a golden opportunity to get the real deal. Every time the NFT collectible is sold the creators a small percentage of profit as royalty.
Till we can control nature, let’s control how we respond to its everchanging nature.
This concept is for state governments of NE India to reduce losses of lives, livestock and materials - caused by annual flooding.
Jeevan Rath – the wheel that keeps spinning bringing relief and response to the most vulnerable
Collective efforts have left footprints stretching from Mumbai across India as volunteers and partners who supported migrant families, people stuck on the road and daily wage earners to reach home continue to reach families and children.
Stephanie Raison
2020...
We all saw the photographs in the media, and we heard some of the stories. A mass of people, many wearing only chappals on their feet, walking for hours under the sun, some carrying children, and sometimes not even knowing if they were going in the right direction.
Many of us watched this unfold via the small screen of our phone, enclosed by our four walls Tweeting Stay Home, Stay Safe. For millions though those walls soon collapsed and some of the hardest hit were in India’s financial capital, Mumbai.
After almost two months of the nation-wide lockdown to prevent the spread of COVID-19, more than 1,200,000 migrant workers who without daily wage jobs were unable to pay their rents in Mumbai. Without anywhere safe to stay they were heading home by train, bus, truck and often just on foot. Approximately 30,000- 40,000 migrants were leaving Mumbai daily.
Even at 10:30 p.m. messages continued to ping on the phones of development workers across Maharashtra. A powerful movement was being set in motion.
We at Hungry Wheels acted as catalysts and created JEEVAN RATH and continued to contributed as mobility partners too with some 55 organizations from across the Maharashtra State that had collectively decided that they were going to do something, together with one goal – to help those most in need through Jeevan Rath - relief on wheels with Hungry Wheels.
https://www.unicef.org/india/stories/jeevan-rath-wheel-keeps-spinning-bringing-relief-and-response-most-vulnerable
Jeevan Rath_ Hungry Wheels Response to Covid19vikram sood
After almost two months of the nation-wide lockdown,
with no access to jobs, unable to pay rent and fearing
for their lives, more than 1,200,000 migrant workers in
Mumbai, are heading home - either by trains, buses,
trucks and most times by foot. Approximately 30,000-
40,000 migrants have been leaving Mumbai daily,
without food and water, in a desperate bid for
survival.
UNICEF would like to appreciate and recognize HUNGRY WHEELS for their dedication and for giving
Jeevan Rath the ability to help as many migrant populations as possible in Maharashtra.
It would further like to commend Hungry Wheels for coming up with the concept of Jeevan Rath, the name of the campaign, as well as contributing the vehicles necessary for making it happen. They were the catalysts that this
movement needed.
Implementers/Collaborators:
321 education foundation, AIILSG, Alert Citizens Foundation, CASA Mumbai, Citizens Association for Child
Rights, CORO, CYDA, Doctors without Borders, Ecosan Services Foundation, Essar Foundation, Family Welfare
Training & Research Centre, FICCI Ladies Association of Mumbai, Geo Roti Ghar, Habitat For Humanity India, Hope
For Children Society, Hungry wheels, India Water Portal, Idobro, Maharashtra State Innovation
Society, Maharashtra State Pollution Control Board, Makaam Maharashtra, Maharashtra State Rural Livelihood
Mission, PriMove India, Project Mumbai, Red is the New Green, Red R, RISE Infinity Foundation, Rotary Club of
Bombay, Samagra, Sato, Lixil, Save the Children, SBM URBAN-Maharashtra, SOS Children's
Villages, SwaCh, Swayam Shikshan Prayog, The LIFE Foundation, The Resilient Foundation, Triratna Prerana
Mandal, UNICEF, Water Supply and Sanitation Department, World Vision India, YMCA Mumbai, Youth for Unity
and Voluntary Action (YUVA), Youth4work, SOPECOM
Donors:
Metro Shoes, Arghyam, United Way Mumbai, Glenmark Foundation, Tech Mahindra Foundation, Shapoorji Palonji,
National Stock Exchange Foundation and Gala.
Brand Elasticity and Architecture by vikram soodvikram sood
In the field of brand management, ‘Brand Elasticity’ is the extent to which an existing or a new brand can be extended across sectors, products or services.
It is the way brands within a company's portfolio can be monetised without increasing branding or marketing costs.
Copyrights: Vikram Sood
VUAR a technology for inclusive tourismvikram sood
TOURISM: IS TRAVEL FOR RECREATIONAL, LEISURE OR BUSINESS PURPOSES.
THE WORLD TOURISM ORGANIZATION DEFINES TOURISTS AS PEOPLE "TRAVELING TO AND STAYING IN PLACES OUTSIDE THEIR USUAL ENVIRONMENT FOR NOT MORE THAN ONE CONSECUTIVE YEAR FOR LEISURE, BUSINESS AND OTHER PURPOSES".
VUAR (Viewable Usable Augment Reality) concept as an enhanced and rich-media story-telling medium at historical monuments pan-India.
2009, Kyoorius Design Yatra. Created an active RFID based event networking platform for Design Yatra to track interactions create networking opportunities and quantify the financial impact of the world’s largest design conference.
A unique service I used to, and sometimes still offer to a select group of brands. Whereby I play the role of their external creative director, showing news ways to see and new ways to think to the companies internal teams. Which can get mired in operations.
2009, Kyoorius Design Yatra
Problem? How do you break-ice between introverts/ creative creators at an event of 2000 plus people?
Solution: Convert the entire space into a RFID mesh. Each participant wears a RFID wrist band.
Each participant's movement creates a Live Digital Painting, on multi-touch screens placed around.
One-click on the person's icon moving around the screen (on phone) reveals three key points to start a conversation, you can also request for a coffee catch-up, and schedule it.
This product is now being licensed out, do feel free to contact.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. INDIA HAS THE
WORST ROAD
TRAFFIC ACCIDENT
RATE WORLDWIDE
> 37.5% OF WORLD’S ROAD DEATHS
> 1,35,000 DEATHS ANNUALLY
> 360 DEATHS PER DAY
> 15 (APPROX.) DEATHS PER HOUR
Courtesy: WHO (World Health Organization) + NCRB (National Crime Records Bureau)
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
3. ANNUAL
MONETARY LOSS
$20 billion
(INR 1 lakh crore).
(2012, IFR (International Road federation) This figure includes expenses
associated with the accident victim, property damage and administration
expenses.) 30% DEATHS CAUSED BY
TRAFFIC ACCIDENTS
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
4. 80% DEATHS CAUSED BY
PUBLIC TRANSPORT
KEY REASONS
- DRUNKEN DRIVING
> CAUSES 95% DEATHS BY TRUCK DRIVERS
> CAUSES 99% OF CITY ACCIDENT DEATHS
- INEFFICIENT LAW ENFORCEMENT
> LACK OF ROAD SAFETY TRAINING
> LACK OF REGULAR TESTS
- INCREASED MOBILITY
> CAR BOOM IN INDIA
> INCREASED INFRASTRUCTURE
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
5. KEY DRIVERS
FOR ACCIDENTS
-95% DEATHS ARE CAUSED BY
TRUCK DRIVERS
-99% ACCIDENTS ARE DUE TO
OVER-SPEEDING
-99% URBAN ACCIDENTS ARE DUE
TO DRUNKEN DRIVING
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
6. NEED GAP
-TRUCK DRIVERS - NEED FOR
EFFICIENT ENFORCEMENT, RE-
EDUCATION, AND HARSH PENALTIES
FOR ERRANT OWNERS
-OVER-SPEEDING - NEED FOR
EFFICIENT ENFORCEMENT, HARSH
PENALTIES FOR DRIVERS AND
PASSENGERS
-DRUNKEN DRIVING - NEED TO TURN
DRUNKEN DRIVING A SHAMEFUL
OFFENSEAND THEN
~ Innovating for growth ~
Friday 4 July 2014
7. -SAFETY MESSAGES ARE
INSTRUCTIONAL, AND DON’T MAKE
AUDIENCES RE-THINK THE
CONSEQUENCES OF THEIR ACTIONS
IN AN ENGAGING MANNER
AND THEN
~ Innovating for growth ~
BEHAVIORAL
AND SIGHT
Friday 4 July 2014
8. ROAD SAFETY
CAMPAIGN TARGET
AUDIENCE
AUDIENCE NEED
STUDENTS (NON-DRIVERS) EDUCATION
STUDENTS (TRAINING-DRIVERS) EDUCATION, TESTING
OWNER DRIVERS RE-TRAINING, TESTING
HIRED DRIVERS OF PRIVATE VEHICLES RE-TRAINING, TESTING
HIRED DRIVERS OF TRANSPORT
VEHICLES
RE-TRAINING, TESTING
HIRED DRIVERS OF PUBLIC
TRANSPORT VEHICLES
RE-TRAINING, TESTING
ACCIDENT VICTIMS
QUICK LOCATION BASED ACCESS TO
TRAUMA CARE IN GOLDEN HOUR
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
10. ROAD ACCESS
PROCESS MAPPING
FOR INTERVENTION
PLANNING
User Journey Brand Intervention
PRE DRIVINGPRE DRIVING
At home Education via engagement
Driving schools Technology innovation
RTOs Technology innovation
DRIVINGDRIVING
Traveller starts engine Reminder communication
Traveller on road Reminder communication
POST ACCIDENTPOST ACCIDENT
Traveller meets with accident Service innovation
Injured traveller en-route to hospital Service innovation
Injured traveller calls insurance co. Service innovation
Insurance co. settles claim CommunicationAND THEN
~ Innovating for growth ~
Friday 4 July 2014
11. CONSUMER
AND SIGHT
AND THEN
~ Innovating for growth ~
CO-CREATING ENGAGING
COMMUNICATION WITH DRIVERS
AND PASSENGERS WILL LEAD TO
SELF REALIZATION OF THE
CONSEQUENCES WITH A LONG TERM
EFFECT
Friday 4 July 2014
12. THE CAMPAIGN
STRATEGY
AND THEN
~ Innovating for growth ~
Co-create.
Make road
safety a
collective
responsibility for
whole families.
Friday 4 July 2014
14. How
Who
What
Earned media:
Brand platform,
Service
Innovations, Brand
Initiatives
Owned media:
Retail points,
Corporate office
external facade,
content,
collaterals
Paid media:
Advertising (TV,
OOH, Radio, print
etc.), search,
digital, mobile,
PR, new media
OPPORTUNITY:
Thought leadership,
via
pre-emptive dialogue
and actions to
influence the
influencers
STRATEGY:
Share, show
convince, consumers
the impact of
collective thinking
TACTICS:
Provide immediate
information and
access to relief, for
accident victims and
family
PASSENGERS
DRIVERS/
RIDERS
VEHICLE
OWNERS
Friday 4 July 2014
22. HOW IT WORKS?
DONATE WORDS
save lives!
CLICK HERE
ALL MESSAGES COME TO
A COMMON WEB PLATFORM
Interactive web banner
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
23. rejected
messages
Inappropriate messages
are barred
NETWORK OPERATING CENTRE
for fan message approval
Aggregated content goes to
Network Operating Centre
for approval
Approved
messages
ALL MESSAGES COME TO
A COMMON PLATFORM
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
24. SELECTED
MESSAGES GET
BEAMED ONTO
TRADITIONAL AND
NEW MEDIAS
MOBILE, ONLINE, SOCIAL
MEDIA
TRAFFIC LEDs
ICONIC PROJECTIONS
TV BROADCAST
PROJECTIONS
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
27. A ANIMATION FILM
COMPETITION FOR
SPREADING ROAD
SAFETY AWARENESS
A platform for engaging creative industry in
advertising, design, and films and creative
students. To create motion content.
Winning entry will be played on TV, and via
ooh networks.
Shortlists will be seeded online.
Friday 4 July 2014
28. CREATE A “ROAD
GUARDIAN”
REPORTER
PROGRAMME
Any one can send in photos/ video of anyone
committing a traffic offense.
We forward these photos/ video as proof
with vehicle number to RTO/ traffic police.
And follow up with the police on fines, all
fines thus collected, should be used to
provide a minimum Rs.1lakh cover/ victim
to hit and run cases against BPL families.
Friday 4 July 2014
29. A DIGITAL + MOBILE
GAME FOR
SPREADING ROAD
SAFETY AWARENESS
An online and on-mobile game for learning,
testing and refreshing road rules knowledge by
playing.
Winners become ambassadors and win awards in
their community eg. truckers, schools, colleges
and get brag rights. They also get extra points for
getting more players.
This game can be used to teach and test public
transport drivers and car owners personal drivers
too.
Friday 4 July 2014
30. C0-BRAND A TAXI/
DRIVER SERVICE
FOR DRUNK
DRIVERS
AND THEN
~ Innovating for growth ~
Friday 4 July 2014
31. MAKE DRUNKEN
DRIVING A
SHAMEFUL OFFENSE
Take the coolness out of drunken driving.
Publish faces of offenders in key OOH
locations, facebook, and print media in
every target city.
Tie-up with local police and press.
Friday 4 July 2014
32. ENCOURAGE HELMET
WEARING BY MAKING
HELMETS COOL
Create a helmet design competition online
Produce and sell helmets in collaboration
from all retail POS outlets.
Friday 4 July 2014
35. CREATE A TRAUMA
AND ACCIDENT
TRAINING
CERTIFICATE
Create a brand extension and offer distance
training via interactive screens in schools and
colleges.
Qualified participants get theory tests.
Final grade applicants give physical exams and
tests.
And get certificates later on. Slowly lobby to make
this mandatory in educational and professional
complexes.
Friday 4 July 2014
36. ‘50505’ CITIZEN SOS
SERVICE
1 NUMBER FOR
ACCIDENT RELIEF ALL
INDIA
Create a location based platform of -
doctors, ambulance services, nurses, and
certified trauma and accident relief
volunteers.
When any person in a road accident SMSes
the number.
The servers locate the nearest doctor,
ambulance or certified trauma and accident
relief volunteer. So help can reach fastest.
Friday 4 July 2014
39. CREAT A CSR/ PPP
PROGRAMME, TO
INSTALL AUTOMATIC
SPEED GUN CAMERAS
90% ACCIDENTS CAN BE AVOIDED BY
JUST SPEED CONTROL
Friday 4 July 2014
40. INITIATE CREATION
OF A UNIFIED
INDIAN ROAD
SIGNAGE SYSTEM
COLLABORATE WITH MINISTRY OF
ROAD AND TRANSPORT, MUNICIPAL
BODIES, AND POLICE
COMMISSIONERS, PSYCHOLOGISTS,
BEHAVIORAL SCIENTISTS AND
DESIGNERS
Friday 4 July 2014
41. CREATE A ‘ROAD
SAFETY RIGHTS’
ORGANIZATION,
WHOSE
VOLUNTEERS
CONDUCTS RANDOM
TESTS OF PUBLIC
TRANSPORT
DRIVERS
AND THEN
~ Innovating for growth ~
Friday 4 July 2014