This document discusses the goals and activities of the Big Data to Knowledge (BD2K) program at the National Institutes of Health (NIH). The BD2K program aims to foster an open digital ecosystem for biomedical research through investing in data science research, establishing appropriate policies and governance, developing necessary infrastructure and tools, and ensuring expertise. It provides funding for centers, workforce development, and other initiatives to support its mission of using data science to accelerate efficient biomedical research. The document outlines BD2K's organization, funding levels over time, and some activities currently outside the program's scope that also support its goals. It emphasizes the importance of cooperation and engagement across efforts to make biomedical data and resources findable, accessible,

1. Towards the digital research enterprise
Philip Bourne, PhD, FACMI
Associate Director for Data Science
November 12, 2015
BD2K All-Hands Meeting 2015
https://docs.google.com/document/d/112QRwNFwpteVBKY9VxbeTUefspThVxisCMglD6Nm5Gw/edit#

2. NIH Office of Biomedical Data
Science Mission Statement
To use data science to foster an
open digital ecosystem that will
accelerate efficient, cost-effective
biomedical research
to enhance health, lengthen life, and
reduce illness and disability
https://datascience.nih.gov/

3. How to foster an open digital ecosystem
for biomedical research?
• Invest in data science research applied to biomedical
research challenges
• Establish appropriate governance and policies
• Develop necessary infrastructure and tools
• Ensure there are people who can make it happen

4. The BD2K Program is Central to the
Mission
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$20,000,000
$40,000,000
$60,000,000
$80,000,000
$100,000,000
$120,000,000
FY14 FY15 FY16 FY17 FY18 FY19 FY20 FY21
total available
BD2K Budget

5. BD2K FY14 Awards
supported by all NIH Institutes

6. BD2K FY14 awards
Centers
bioCADDIE &
supplements
Workforce
Development
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7. BD2K FY15 awards
Centers
bioCADDIE &
supplements
Workforce
Development
Commons
Supplements
Centers
Supplements
Centers
Coordination
supplement
Training
Coordination
award
Standards
Coordination
contract
Cloud Broker
contract
HMP commons
pilot supplement
Interoperability
supplements
More Workforce
Development
Targeted
Software
awards
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8. BD2K organization
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9. BD2K organization
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Data
Science
Research
Infrastructure
Workforce
Development
Commons

10. BD2K organization
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Data Science
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Workforce
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B
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BD2K
Data Science at NIH

13. Activities Currently Outside of BD2K
• Homogenization of Common Data
Elements (CDEs)
• Sustainability
• Policy & process development
• Reference data
• International and interagency cooperation

14. How to foster an open digital ecosystem
for biomedical research?
•Be FAIR:
• Findable
• Accessible
• Interoperable
• Reusable

15. Being FAIR Needs a High Level of
Cooperation
• BioCADDIE is prototyping a data indexing system – the time to
engage is now
• Helping to decide what content to index with emphasis on value to
a broad community and found in the Commons
• Provide feedback on the emerging prototype
• Recognize that different indexing of methods and types of
content is on-going
• An NIH Research Index Working Group led by Vivien Bonazzi is to
help coordinate and encourage engagement
• Work with BioCADDIE to integrate other efforts to support a
single meta index

16. NIH…
Turning Discovery Into Health
philip.bourne@nih.gov
https://datascience.nih.gov/