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Thermoregulation of
Body
The maintenance of a particular temperature in a living
body.
Overview of Thermoregulation
 Mechanisms of Thermoregulation
 Exercise in Heat Stress
 Heat Illness
 Exercise in Cold Stress
Thermal Balance
 Core temperature (TCO) is in dynamic
equilibrium as a result of balance between
heat gain and heat loss.
 Mean body temperature (Tbody) represents
an average of skin and internal
temperatures.
Hypothalamus Regulation of
Temperature
 Hypothalamus acts
as “thermostat”
that makes
thermoregulatory
adjustments to
deviations from
temperature norm
in the brain (37 C
± 1 C or
98.6±1.8 F ).
Hypothalamus Regulation of
Temperature
 Mechanisms are
activated in two
ways:
◦ Thermal receptors in
skin provide input to
central command
◦ Direct stimulation of
hypothalamus
through changes in
blood temperature
perfusing area
Thermoregulation in Cold
 Vascular adjustments: constrict peripheral
blood vessels.
 Muscular activity: exercise energy
metabolism and shivering.
 Hormonal output: epinephrine and
norepinephrine increase basal heat
production; prolonged cold – thyroxin.
Thermoregulation in Heat
Thermoregulation in Heat
 Heat Loss by Radiation (~ 10%)
◦ Objects emit electromagnetic heat waves
without molecular contact with warmer objects.
◦ When temperature of things in environment
exceeds the skin temperature, radiant heat
energy is absorbed from the surroundings.
Thermoregulation
Thermoregulation in Heat
 Heat Loss by Conduction
◦ Direct transfer of heat through a liquid, solid, or
gas from one molecule to another.
◦ A small amount of body heat moves by
conduction directly through deep tissues to
cooler surface. Heat loss involves the warming
of air molecules and cooler surfaces in contact
with the skin.
◦ The rate of conductive heat loss depends on
thermal gradient.
Thermoregulation in Heat
 Heat Loss by Convection (+ conduction
35%)
◦ Effectiveness depends on how rapidly the air (or
water) adjacent to the body is exchanged.
◦ Air currents at 4 mph are about twice as effective
for cooling air currents at 1 mph.
Thermoregulation in Heat
 Heat Loss by Evaporation (~ 55%)
◦ Heat transferred as water is vaporized from
respiratory passages and skin surfaces.
◦ For each liter of water vaporized, 580 kcal
transferred to the environment.
◦ When sweat comes in contact with the skin, a
cooling effect occurs as sweat evaporates.
◦ The cooled skin serves to cool the blood.
Heat Loss at High Ambient
Temperatures
 Effectiveness of heat loss via conduction,
convection, and radiation decreases.
 When ambient temperature exceeds body
temperature, heat is gained.
 The only effective mechanism is
evaporation of sweat and respiratory tract
vaporization of water.
Heat Loss in High Humidity
 Total sweat vaporized from skin depends on:
◦ Surface area exposed to environment
◦ Temperature and humidity of ambient air
◦ Convective air currents about the body
 Most important factor is relative humidity.
 When relative humidity is high, the ambient
water vapor pressure approaches that of the
moist skin and evaporation is impeded.
Integration of Heat-Dissipating
Mechanisms
 Circulation.
Superficial venous
and arterial blood
vessels dilate to
divert warm blood
to the body shell.
Integration of Heat-
Dissipating Mechanisms
 Evaporation. Sweating
begins within 1.5 s
after start of vigorous
exercise.
 Hormonal adjustments.
Certain hormonal
adjustments are
initiated in heat stress
as body attempts to
conserve fluids and
sodium.
Hormones in Heat Stress
 Antidiuretic
hormone (ADH) is
released to increase
water re-absorption
from kidneys.
 Aldosterone is
released to increase
the re-absorption of
sodium.
Effects of Clothing
Cold Weather Clothing
provide an air
barrier to prevent
convection and
conduction.
 Layers provide more
trapped air
 Allow water vapor to
escape
Warm Weather
Clothing loose
fitting to permit free
convection.
 The less surface
covered the more
evaporative cooling.
 Clothing should be
loosely woven to
allow skin to
breathe.
Exercise in Heat Stress
 Circulatory Adjustments.
◦ Cardiovascular drift – fluid loss reduces plasma
volume (about 10% of fluid lost comes from
plasma. About 50% comes from intracellular
water).
◦ Visceral vascular constriction and skin & muscle
vascular dilation.
◦ Maintaining blood pressure. Circulatory regulation
and maintenance of muscle blood flow take
precedence over temperature regulation often at
the expense of spiraling core temperature during
exercise in heat.
Exercise in Heat Stress
 Core temperature
◦ More than likely a
modest increase in
core temperature
reflects favorable
internal
adjustments.
Water Loss in the Heat
 Magnitude of Fluid Loss in Exercise.
 Consequences of Dehydration.
◦ plasma volume   peripheral blood flow &
sweat rate
 Water Replacement
◦ Primary aim of fluid replacement during
exercise is to maintain plasma volume
◦ The most effective defense against heat stress
is adequate hydration
 Electrolyte Replacement.
Acclimatization to Heat
Acclimatization refers to physiological
changes that improve heat tolerance.
2 – 4 hours daily heat exposure produce
complete acclimatization 5-10 days.
o Rectal temperature
• HR
∆ Sweat rate
Factors that Improve Heat
Tolerance: Acclimatization
Improved cutaneous blood flow Transports metabolic heat from deep
tissues to body’s shell
Effective distribution of cardiac output Appropriate circulation to skin &
muscles to meet demands.
Lowered threshold for start of sweating Evaporative cooling begins early in
exercise.
More effective distribution of sweat
over skin surface
Optimum use of surface for effective
evaporative cooling.
Increased rate of sweating Maximize evaporative cooling.
Decreased salt concentration of sweat Dilute sweat preserves electrolyte in
fluids.
Factors that Improve Heat
Tolerance
 Fitness Level
 Age (see FYI)
Aging delays the onset of sweating and blunts
the magnitude of sweating response
 Gender
 Body fatness
Evaluating Heat Stress
 Prevention remains
most effective way
to manage heat-
stress injuries
 Wet bulb-globe
temperature relies
on ambient
temperature,
relative humidity,
and radiant heat.
 Heat stress index
Heat Illness
Heat Illness
Prevention of Heat Illness
 Allow adequate time for acclimatization.
 Exercise during cooler parts of day.
 Limit/defer exercise if heat stress index is in
high risk zone.
 Hydrate properly prior to exercise and
replace fluid loss during and after exercise.
 Wear clothing that is light in color and loose
fitting.
Exercise in the Cold
 Cold strain
◦ Exposure to cold produces physiological & psychological
challenges
◦ Body fat differences effect physiological function in cold
 Acclimatization to the Cold
Humans adapt more successfully to chronic heat than cold
exposure.
Exercise in the Cold
 Evaluating Environmental
Cold Stress
◦ Wind chill index
 Respiratory tract in Cold
◦ Cold air does not damage
respiratory passages.
◦ Air warms to between 80°
F to 90° F as it reaches
bronchi.
◦ Humidification of inspired
cold air produces water &
heat loss from respiratory
tract.

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thermoregulation in human body

  • 1. Thermoregulation of Body The maintenance of a particular temperature in a living body.
  • 2. Overview of Thermoregulation  Mechanisms of Thermoregulation  Exercise in Heat Stress  Heat Illness  Exercise in Cold Stress
  • 3. Thermal Balance  Core temperature (TCO) is in dynamic equilibrium as a result of balance between heat gain and heat loss.  Mean body temperature (Tbody) represents an average of skin and internal temperatures.
  • 4. Hypothalamus Regulation of Temperature  Hypothalamus acts as “thermostat” that makes thermoregulatory adjustments to deviations from temperature norm in the brain (37 C ± 1 C or 98.6±1.8 F ).
  • 5. Hypothalamus Regulation of Temperature  Mechanisms are activated in two ways: ◦ Thermal receptors in skin provide input to central command ◦ Direct stimulation of hypothalamus through changes in blood temperature perfusing area
  • 6. Thermoregulation in Cold  Vascular adjustments: constrict peripheral blood vessels.  Muscular activity: exercise energy metabolism and shivering.  Hormonal output: epinephrine and norepinephrine increase basal heat production; prolonged cold – thyroxin.
  • 8. Thermoregulation in Heat  Heat Loss by Radiation (~ 10%) ◦ Objects emit electromagnetic heat waves without molecular contact with warmer objects. ◦ When temperature of things in environment exceeds the skin temperature, radiant heat energy is absorbed from the surroundings.
  • 10. Thermoregulation in Heat  Heat Loss by Conduction ◦ Direct transfer of heat through a liquid, solid, or gas from one molecule to another. ◦ A small amount of body heat moves by conduction directly through deep tissues to cooler surface. Heat loss involves the warming of air molecules and cooler surfaces in contact with the skin. ◦ The rate of conductive heat loss depends on thermal gradient.
  • 11. Thermoregulation in Heat  Heat Loss by Convection (+ conduction 35%) ◦ Effectiveness depends on how rapidly the air (or water) adjacent to the body is exchanged. ◦ Air currents at 4 mph are about twice as effective for cooling air currents at 1 mph.
  • 12. Thermoregulation in Heat  Heat Loss by Evaporation (~ 55%) ◦ Heat transferred as water is vaporized from respiratory passages and skin surfaces. ◦ For each liter of water vaporized, 580 kcal transferred to the environment. ◦ When sweat comes in contact with the skin, a cooling effect occurs as sweat evaporates. ◦ The cooled skin serves to cool the blood.
  • 13. Heat Loss at High Ambient Temperatures  Effectiveness of heat loss via conduction, convection, and radiation decreases.  When ambient temperature exceeds body temperature, heat is gained.  The only effective mechanism is evaporation of sweat and respiratory tract vaporization of water.
  • 14. Heat Loss in High Humidity  Total sweat vaporized from skin depends on: ◦ Surface area exposed to environment ◦ Temperature and humidity of ambient air ◦ Convective air currents about the body  Most important factor is relative humidity.  When relative humidity is high, the ambient water vapor pressure approaches that of the moist skin and evaporation is impeded.
  • 15. Integration of Heat-Dissipating Mechanisms  Circulation. Superficial venous and arterial blood vessels dilate to divert warm blood to the body shell.
  • 16. Integration of Heat- Dissipating Mechanisms  Evaporation. Sweating begins within 1.5 s after start of vigorous exercise.  Hormonal adjustments. Certain hormonal adjustments are initiated in heat stress as body attempts to conserve fluids and sodium.
  • 17. Hormones in Heat Stress  Antidiuretic hormone (ADH) is released to increase water re-absorption from kidneys.  Aldosterone is released to increase the re-absorption of sodium.
  • 18. Effects of Clothing Cold Weather Clothing provide an air barrier to prevent convection and conduction.  Layers provide more trapped air  Allow water vapor to escape Warm Weather Clothing loose fitting to permit free convection.  The less surface covered the more evaporative cooling.  Clothing should be loosely woven to allow skin to breathe.
  • 19. Exercise in Heat Stress  Circulatory Adjustments. ◦ Cardiovascular drift – fluid loss reduces plasma volume (about 10% of fluid lost comes from plasma. About 50% comes from intracellular water). ◦ Visceral vascular constriction and skin & muscle vascular dilation. ◦ Maintaining blood pressure. Circulatory regulation and maintenance of muscle blood flow take precedence over temperature regulation often at the expense of spiraling core temperature during exercise in heat.
  • 20. Exercise in Heat Stress  Core temperature ◦ More than likely a modest increase in core temperature reflects favorable internal adjustments.
  • 21. Water Loss in the Heat  Magnitude of Fluid Loss in Exercise.  Consequences of Dehydration. ◦ plasma volume   peripheral blood flow & sweat rate  Water Replacement ◦ Primary aim of fluid replacement during exercise is to maintain plasma volume ◦ The most effective defense against heat stress is adequate hydration  Electrolyte Replacement.
  • 22. Acclimatization to Heat Acclimatization refers to physiological changes that improve heat tolerance. 2 – 4 hours daily heat exposure produce complete acclimatization 5-10 days. o Rectal temperature • HR ∆ Sweat rate
  • 23. Factors that Improve Heat Tolerance: Acclimatization Improved cutaneous blood flow Transports metabolic heat from deep tissues to body’s shell Effective distribution of cardiac output Appropriate circulation to skin & muscles to meet demands. Lowered threshold for start of sweating Evaporative cooling begins early in exercise. More effective distribution of sweat over skin surface Optimum use of surface for effective evaporative cooling. Increased rate of sweating Maximize evaporative cooling. Decreased salt concentration of sweat Dilute sweat preserves electrolyte in fluids.
  • 24. Factors that Improve Heat Tolerance  Fitness Level  Age (see FYI) Aging delays the onset of sweating and blunts the magnitude of sweating response  Gender  Body fatness
  • 25. Evaluating Heat Stress  Prevention remains most effective way to manage heat- stress injuries  Wet bulb-globe temperature relies on ambient temperature, relative humidity, and radiant heat.  Heat stress index
  • 28. Prevention of Heat Illness  Allow adequate time for acclimatization.  Exercise during cooler parts of day.  Limit/defer exercise if heat stress index is in high risk zone.  Hydrate properly prior to exercise and replace fluid loss during and after exercise.  Wear clothing that is light in color and loose fitting.
  • 29. Exercise in the Cold  Cold strain ◦ Exposure to cold produces physiological & psychological challenges ◦ Body fat differences effect physiological function in cold  Acclimatization to the Cold Humans adapt more successfully to chronic heat than cold exposure.
  • 30. Exercise in the Cold  Evaluating Environmental Cold Stress ◦ Wind chill index  Respiratory tract in Cold ◦ Cold air does not damage respiratory passages. ◦ Air warms to between 80° F to 90° F as it reaches bronchi. ◦ Humidification of inspired cold air produces water & heat loss from respiratory tract.