Various neurotransmitters, mechanism of action and their physiological functions are explained and is useful for ug and pg students of medicine, neurology, psychiatry branches.
this ppt shares what synapses are and how information of one neuron is transmitted to other through the synapses. it also includes the properties and plasticity of synaptic transmission
Various neurotransmitters, mechanism of action and their physiological functions are explained and is useful for ug and pg students of medicine, neurology, psychiatry branches.
this ppt shares what synapses are and how information of one neuron is transmitted to other through the synapses. it also includes the properties and plasticity of synaptic transmission
Nephron (The Guyton and Hall physiology)Maryam Fida
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Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMANâS CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowmanâs capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowmanâs capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowmanâs capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
Nervous system forms an interconnecting fibers of communication network.
In the âhard-wiringâ of the nerves, the signals travel in the form of a flow of electrical current called nerve impulses.
The stimulus-response reactions afford internal constancy in the face of environmental changes.
these slides contain a brief introduction of neurons and its classification as well as details of generation of action potential, resting potential and eletrotonic potential.
Action potential By Dr. Mrs. Padmaja R Desai Physiology Dept
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To study the Concept of Action Potential and describe the stages of action potential.
Ionic basis of Action Potential & its Propogation.
Properties of Action Potential.
Types action Potential
Nephron (The Guyton and Hall physiology)Maryam Fida
Â
Structural and Functional unit of kidney is called nephron.
There are about 1.3 million nephron in each kidney.
New nephrons can not be regenerated by kidneys.
Functioning nephrons decrease about 10 % every 10 years at the age of 40.
At the age of 80, there are 40 % of functioning nephrons as compared to 40 yrs.
It is formed by two parts.
1. GLOMERULUS
2. BOWMANâS CAPSULE
1- Glomerulus:
It consists of tuft of glomerular capillaries.
There is anastomosing & branching network of glomerular capillaries.
Glomerular capillaries have high hydrostatic pressure (nearly 60 mm Hg) as compared with other capillaries.
Glomerulus is surrounded by a membranous cover called Bowmanâs capsule.
Each glomerulus is about 0.2 mm in diameter.
Glomerulus and Bowmanâs capsule together constitute renal corpuscle.
Each renal tubule is divided into various part as they have different functions.
i- Proximal convulated tubule.
It is continuation of Bowmanâs capsule.
ii- Loop of Henle. It is continuation of prox. conv. tubule.
* Loop of Henle has three parts.
a- descending limb,
b- u turn or bend in medulla and
c- ascending limb.
Ascending limb has initial thin segment followed by thick segment.
At the end of thick ascending limb, there is short segment called macula densa, which plays important role in controlling functions of nephron.
Nervous system forms an interconnecting fibers of communication network.
In the âhard-wiringâ of the nerves, the signals travel in the form of a flow of electrical current called nerve impulses.
The stimulus-response reactions afford internal constancy in the face of environmental changes.
these slides contain a brief introduction of neurons and its classification as well as details of generation of action potential, resting potential and eletrotonic potential.
Action potential By Dr. Mrs. Padmaja R Desai Physiology Dept
Â
To study the Concept of Action Potential and describe the stages of action potential.
Ionic basis of Action Potential & its Propogation.
Properties of Action Potential.
Types action Potential
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an easy introduction of nervous system. Detail theoretical information purposefully avoided. At the beginning of medical course, also biology student need to know about nervous system. Within short time this presentation give a simple overview of NS.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
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As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Departmentâs official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
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i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Drug Discovery and Development .....NEHA GUPTA
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The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganongâs Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
2. Lecture Outline
âą General Overview of Nervous System
Function
âą Cells of the Nervous System
âą CNS
â Functional components
â Neural networks
â Organization of the CNS
5. The Nervous System
Cells of the Nervous System
âą Cells are grouped into two functional categories
â Neurons
âą Do all of the major functions on their own, are
1. Afferent
2. Interneurons
3. Efferent
â Neuroglia
âą Play a supporting role to the neurons
âą Divided into CNS and PNS Neuroglia
â CNS
» Astrocytes
» Oligodendrocytes
» Microglia
» Ependymal cells
â PNS
» Neurolemmocytes
» Satellite cells
6. âą The general neuron
& itâs function
The Nervous System
Cells of the Nervous System
7. âą Neurons
â Functional Classification
1. Afferent
â Conduct APs to the CNS
The Nervous System
Cells of the Nervous System
8. The Nervous System
Cells of the Nervous System
âą Neurons
â Functional Classification
2. Interneurons
â Conduct APs within the
CNS
9. âą Neurons
â Functional Classification
3. Efferent
â Conduct APs to the PNS
The Nervous System
Cells of the Nervous System
11. âą What are the major functional components
of the Nervous System?
â Brain
â Spinal Cord
â Afferent Tracts
â Efferent Tracts
â Ganglia
The Nervous System
Functional Components
Central Nervous
System
Peripheral Nervous
System
12. âą How do the structural components allow the nervous
system to function correctly?
â Provides protected environment
âą Bony protection
âą Meninges
âą Blood brain barrier
âą Maintain correct ECF parameters
âą How do the functional components
allow the nervous system to
function correctly
â Creates and modifies
neuronal circuits organized into
âą afferent & efferent tracts
âą Functional areas in the CNS
â Gray & white matter
âą Reflex pathways
The Nervous System
Functional Components
17. âą Neuronal Circuits
â The design of the circuit (arrangement of
neurons) determines
âą Level of divergence or convergence
â Spread or shrinkage of information
âą Speed
âą If a circuit will be autorhythmic
â There is plasticity to neuronal circuits
The Nervous System
Functional Components
18. âą Serial & Parallel Circuits
The Nervous System
Functional Components
19. âą Converging vs. Diverging Circuits
The Nervous System
Functional Components
20. âą Parallel After Discharge Circuit
The Nervous System
Functional Components
22. The Nervous System
Reflex Pathways
âą What are reflexes?
âą Types
â Monosynpatic vs. polysynaptic
â Contralateral, bilateral, ipsilateral
â Lab Session on ReflexesâŠ
23. The Nervous System
Organization of the CNS
âą Central Nervous System is divided into
two functional groups
â The brain
â The spinal cord
â What goes on in these two different areas?
âą Sensory aspect
âą Integrative aspect
âą Motor aspect
24. The Nervous System
Organization of the CNS
âą The Brain
â Functional organization
âą Neuronal circuits organized into
â Gray matter & White Matter
Gray Matter
Consists of
â Non myelinated axon terminals
â Dendrites
â Cell Bodies
Functions in
â signal processing (integration)
â Neurocrine / neurohormone
secretion
White Matter
Consists of
â Myelinated axons
Functions in
â Formation of tracts
âą ascending or descending (SC)
âą commissural, association,
projection (B)