There are four major types of neuroglial cells in the central nervous system: astrocytes, ependymal cells, microglial cells, and oligodendrocytes. Astrocytes regulate the flow of ions and molecules to and from neurons. Ependymal cells line the brain ventricles and spinal cord canal and produce cerebrospinal fluid. Microglial cells support neurons by phagocytizing dead cells and debris. Oligodendrocytes insulate axons with myelin to speed signal transmission between neurons.