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• General anatomy of nervous system
Nervous system
• Nervous system
integrates these
sensory information,
store information as
memory
Nervous system receives sensory
information
•From external environment
(temperature, vision, sound etc.)
•From body (touch, pressure, pain etc.)
Nervous system makes an appropriate
response, ex: movement of muscles
Simple flowchart of nervous system function
Skin > touch
> nerve (sensory nerve/afferent
fibre/ascending tract)
Brain
 nerve(motor nerve/efferent
fibres/descending tract)
 muscle> movement
CNS : PRINCIPLES ROLES
• Integrate and coordinate
incoming and outgoing neural
signals
• Carry out higher mental
functions such as thinking and
learning
Division of nervous system
• Structurally,
• Central nervous
system
Brain Spinal cord
• Peripheral nervous
system
Cranial nerves, Spinal
nerves, Autonomic
nerves
Functional division
Somatic nervous system,
is the part of
nervous
system which
control voluntary
activities
Autonomic nervous system,
is the part of nervous
system concerned with
the innervation of
involuntary structures,
such as the heart,
smooth muscle, and
glands within the body
What is the composition of nervous tissue?
1. Neuron ( nerve cell ) 2. Neuroglia
Nerve cell body Processes
Dendrite Axon
Nerve cell body
Nerve cell processes
Dendrite
Axon
Histological feature of neuron
nerve cell body
A centrally placed
spherical, unusually
large , euchromatic
(pale-staining)
nucleus with a
prominent
nucleolus,
Nissl body unique feature of neuron
Nissl bodies are
basophilic granular
areas formed by
the rER , iron &
free ribosomes.
Golgi complex
arranged
around the
periphery of
the nucleus.
Mitochondria are found through out of the cell body,
dendrites, and axons. They are spherical or rod shaped.
Axon hillock :
it is the area of
cell body which is
free of large
cytoplasmic
organelles. It is a
landmark to
distinguish
between axons
and dendrites in
both light & TEM
microscopes.
• Dendrites are
receptor processes that
receive stimuli from
other neurons or from
the external
environment
• Axon are effector
processes that transmit
stimuli to other
neurons or effector
cells
What is gray matter and
white matter?
Grey matter
Nerve cell body
Neuroglia
Blood vessel
White matter
Nerve processes
Neuroglia
Blood vessels
Neuroglia
Blood vessels
• Gray matter: Neuron cell bodies
Neuroglial cells
Blood vessels
• White matter: Processes of neuron
Neuroglial cells
Blood vessels
Location of gray & white matter in the CNS
• Cerebrum and
cerebellum ,
• Outer gray matter
• Inner white matter
• Spinal cord,
• outer part white
matter
• Inner gray matter
Gray matter matter
Classification of neuron
According to the polarity
According to function
Sensory neuron
Motor neuron
Neuroglia
• The neuron of the central nervous system are
supported by several varieties of non excitable
cells, which together are called neuroglia.
• They are smaller than the neuron
• Number of them 5-10 times greater than the
neuron
There are four types of neuroglial cells in CNS &
two types in PNS:
CNS
1. Astrocytes
(a) fibrous
(b) protoplasmic
2. Oligodendrocytes
3. Microglia
4. Ependyma
• PNS
1. Schwann cells
2. Satellite cells.
Protoplasmic Astrocytes Fibrous Astrocytes
Oligodendrocytes Microglia
Ependyma
Schwann cells:
It have the same
function as
oligodendrocytes but
are located around
axons in the peripheral
NS.
Axon
Functions of neuroglia
Name of the neuroglia Functions
Astrocytes Formation of blood brain barrier
Oligodendrocyte Myelination of nerve fibers in the CNS
Ependymal cells secrete, circulate and absorbed CSF
Microglia Phagocytic function in inflamed
brain (They are inactive in normal
brain)
Schwann cells Myelination of nerve fibers in the PNS
Development of neuroglia
Name of the
neuroglia
Functions
Astrocytes Neuroectoderm
Oligodendrocyte Neuroectoderm
Ependymal cells Neuroectoderm
Microglia Mesodermal in origin
Schwann cells Neural crest
What is myelin sheath?
• Axon of neuron is covered by
sheaths which are modified cell
membranes of schwann cells in PNS
and oligodendrocytes in CNS
Schwann
cells
Axon
Schwann cells undergo
spiraling around the axon
Myelination in the CNS by oligodendrocyte
Function of myelination
• It acts as an insulator
• Helps in impulse conduction
Ganglia
a collection of nerve cell bodies out side the
CNS
1. sensory ganglia of spinal nerves
(posterior root ganglia) and
cranial nerves
2. autonomic ganglia
Nucleus: a collection of nerve cell bodies of
neuron in the CNS is called nucleus
Example:
Dorsal nucleus of vagus
nucleus ambiguous,
nucleus of tractus solitarius
Grey matter
White matter
Nucleus
What is synapse?
• The synapse is the specialised
junctions between two or
more adjacent neurons.
How impulse go from one neuron to
another ?
What are the types of synapses?
According to the location of synapse in the post
synaptic neurons
• How nervous system is
worked ?
Simple reflex arc
Reflex arc
• A reflex may be define as an involuntary response
to a stimulus. It depends on the integrity of the
reflex arc .
A reflex arc consists of the following anatomical
structures:
Location
1) a receptor organ Skin, muscle, or tendon
2) an afferent neuron Posterior root ganglion
3) an effector neuron Example: Lower motor
neuron located in the
ventral horn of spinal
cord
4) an effector organ Example: Skeletal muscle
Structural organization of reflex may be two
types
•Monosynaptic reflex
Incoming axons of
the unipolar
primary sensory
neurons synapse
directly on a motor
neuron.
Example: tendon jerks
•Polysynaptic reflex
In these reflex one
or more
interneurons,
excitatory or
inhibitory,
intervene between
sensory and motor
neurons.
Polysynaptic reflex
Types of reflex
• Reflex may be divided into 4 groups:
1) superficial (or skin and mucous membrane) reflexes
Corneal reflexes, gag reflexes
2) deep (or myotatic) reflexes
Jaw jerk, knee jerk
3) visceral ( or organic) reflexes
Pupillary reflex
4) pathological (or abnormal) reflexes
Ankle clonus, Babinski’s sign

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Nervous system easy introduction

  • 1. • General anatomy of nervous system
  • 2. Nervous system • Nervous system integrates these sensory information, store information as memory Nervous system receives sensory information •From external environment (temperature, vision, sound etc.) •From body (touch, pressure, pain etc.) Nervous system makes an appropriate response, ex: movement of muscles
  • 3.
  • 4. Simple flowchart of nervous system function Skin > touch > nerve (sensory nerve/afferent fibre/ascending tract) Brain  nerve(motor nerve/efferent fibres/descending tract)  muscle> movement
  • 5. CNS : PRINCIPLES ROLES • Integrate and coordinate incoming and outgoing neural signals • Carry out higher mental functions such as thinking and learning
  • 6. Division of nervous system • Structurally, • Central nervous system Brain Spinal cord • Peripheral nervous system Cranial nerves, Spinal nerves, Autonomic nerves
  • 7.
  • 8. Functional division Somatic nervous system, is the part of nervous system which control voluntary activities Autonomic nervous system, is the part of nervous system concerned with the innervation of involuntary structures, such as the heart, smooth muscle, and glands within the body
  • 9.
  • 10. What is the composition of nervous tissue? 1. Neuron ( nerve cell ) 2. Neuroglia Nerve cell body Processes Dendrite Axon
  • 11. Nerve cell body Nerve cell processes Dendrite Axon
  • 12. Histological feature of neuron nerve cell body A centrally placed spherical, unusually large , euchromatic (pale-staining) nucleus with a prominent nucleolus,
  • 13. Nissl body unique feature of neuron Nissl bodies are basophilic granular areas formed by the rER , iron & free ribosomes.
  • 15. Mitochondria are found through out of the cell body, dendrites, and axons. They are spherical or rod shaped.
  • 16. Axon hillock : it is the area of cell body which is free of large cytoplasmic organelles. It is a landmark to distinguish between axons and dendrites in both light & TEM microscopes.
  • 17. • Dendrites are receptor processes that receive stimuli from other neurons or from the external environment • Axon are effector processes that transmit stimuli to other neurons or effector cells
  • 18. What is gray matter and white matter?
  • 19. Grey matter Nerve cell body Neuroglia Blood vessel White matter Nerve processes Neuroglia Blood vessels Neuroglia Blood vessels
  • 20. • Gray matter: Neuron cell bodies Neuroglial cells Blood vessels • White matter: Processes of neuron Neuroglial cells Blood vessels
  • 21. Location of gray & white matter in the CNS • Cerebrum and cerebellum , • Outer gray matter • Inner white matter • Spinal cord, • outer part white matter • Inner gray matter
  • 23.
  • 24.
  • 26. According to function Sensory neuron Motor neuron
  • 27. Neuroglia • The neuron of the central nervous system are supported by several varieties of non excitable cells, which together are called neuroglia. • They are smaller than the neuron • Number of them 5-10 times greater than the neuron
  • 28. There are four types of neuroglial cells in CNS & two types in PNS: CNS 1. Astrocytes (a) fibrous (b) protoplasmic 2. Oligodendrocytes 3. Microglia 4. Ependyma • PNS 1. Schwann cells 2. Satellite cells.
  • 29.
  • 33. Schwann cells: It have the same function as oligodendrocytes but are located around axons in the peripheral NS. Axon
  • 34. Functions of neuroglia Name of the neuroglia Functions Astrocytes Formation of blood brain barrier Oligodendrocyte Myelination of nerve fibers in the CNS Ependymal cells secrete, circulate and absorbed CSF Microglia Phagocytic function in inflamed brain (They are inactive in normal brain) Schwann cells Myelination of nerve fibers in the PNS
  • 35. Development of neuroglia Name of the neuroglia Functions Astrocytes Neuroectoderm Oligodendrocyte Neuroectoderm Ependymal cells Neuroectoderm Microglia Mesodermal in origin Schwann cells Neural crest
  • 36. What is myelin sheath? • Axon of neuron is covered by sheaths which are modified cell membranes of schwann cells in PNS and oligodendrocytes in CNS
  • 38.
  • 39. Myelination in the CNS by oligodendrocyte
  • 40. Function of myelination • It acts as an insulator • Helps in impulse conduction
  • 41. Ganglia a collection of nerve cell bodies out side the CNS 1. sensory ganglia of spinal nerves (posterior root ganglia) and cranial nerves 2. autonomic ganglia
  • 42.
  • 43. Nucleus: a collection of nerve cell bodies of neuron in the CNS is called nucleus Example: Dorsal nucleus of vagus nucleus ambiguous, nucleus of tractus solitarius
  • 45.
  • 46. What is synapse? • The synapse is the specialised junctions between two or more adjacent neurons.
  • 47. How impulse go from one neuron to another ?
  • 48.
  • 49. What are the types of synapses? According to the location of synapse in the post synaptic neurons
  • 50. • How nervous system is worked ?
  • 52.
  • 53. Reflex arc • A reflex may be define as an involuntary response to a stimulus. It depends on the integrity of the reflex arc . A reflex arc consists of the following anatomical structures: Location 1) a receptor organ Skin, muscle, or tendon 2) an afferent neuron Posterior root ganglion 3) an effector neuron Example: Lower motor neuron located in the ventral horn of spinal cord 4) an effector organ Example: Skeletal muscle
  • 54. Structural organization of reflex may be two types •Monosynaptic reflex Incoming axons of the unipolar primary sensory neurons synapse directly on a motor neuron. Example: tendon jerks •Polysynaptic reflex In these reflex one or more interneurons, excitatory or inhibitory, intervene between sensory and motor neurons.
  • 56. Types of reflex • Reflex may be divided into 4 groups: 1) superficial (or skin and mucous membrane) reflexes Corneal reflexes, gag reflexes 2) deep (or myotatic) reflexes Jaw jerk, knee jerk 3) visceral ( or organic) reflexes Pupillary reflex 4) pathological (or abnormal) reflexes Ankle clonus, Babinski’s sign