The document summarizes the structure and function of the major parts of the human brain. It describes how the hindbrain carries out basic functions like autonomic functions and sleep control. The midbrain coordinates signals by filtering sensory input. The forebrain processes signals, stores memories, and enables higher thought. It then provides more detail on the specific regions within these areas like the cortex, limbic system, cerebellum, and lobes of the cerebrum and their roles in functions like memory, movement, sensory processing, language, and emotion.
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column. It encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and entering the spinal canal at the beginning of the cervical vertebrae.
The brain is one of the largest and most complex organs in the human body. It is made up of more than 100 billion nerves that communicate in trillions of connections called synapses. ... The brain stem is between the spinal cord and the rest of the brain. Basic functions like breathing and sleep are controlled here.
The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column. It encloses the central canal of the spinal cord, which contains cerebrospinal fluid. The brain and spinal cord together make up the central nervous system (CNS). In humans, the spinal cord begins at the occipital bone, passing through the foramen magnum and entering the spinal canal at the beginning of the cervical vertebrae.
The brain is one of the largest and most complex organs in the human body. It is made up of more than 100 billion nerves that communicate in trillions of connections called synapses. ... The brain stem is between the spinal cord and the rest of the brain. Basic functions like breathing and sleep are controlled here.
The detail description about peripheral nervous system, neuron, its covering, types of neuron, synapses, spinal nerves, plexus, and more about cranial nerves at last not the least about somatic and autonomic nervous system. you may also find the information about types of peripheral nervous system in detail.
Peripheral Nervous System, Audumbar MaliAudumbar Mali
Peripheral Nervous System,
Types of PNS,
Spinal nerves,
Types of neuron (3 basic types),
Plexus,
Cranial nerves,
Autonomic nervous system,
Structure of Neuron,
Human Anatomy and Physiology-I,
Syllabus As per PCI,
B. Pharm-I
Unit-I, Chapter_1 Nervous System Final PPT.pptAudumbar Mali
B. Pharm. Sem:-II,
BP 201T. HUMAN ANATOMY AND PHYSIOLOGY-II (Theory),
Nervous System:
Organization of nervous system, neuron, neuroglia, classification and properties of nerve fibre, electrophysiology, action potential, nerve impulse, receptors, synapse, neurotransmitters. Central nervous system: Meninges, ventricles of brain and
cerebrospinal fluid.structure and functions of brain (cerebrum, brain stem, cerebellum), spinal cord (gross structure, functions of afferent and efferent nerve tracts,reflex activity).
The nervous system is the body's main communication system; it gathers, synthesizes, and uses data from the environment. The most basic unit of the nervous system is the neuron, which serves as both a sensor and communicator of internal and external stimuli.
The detail description about peripheral nervous system, neuron, its covering, types of neuron, synapses, spinal nerves, plexus, and more about cranial nerves at last not the least about somatic and autonomic nervous system. you may also find the information about types of peripheral nervous system in detail.
Peripheral Nervous System, Audumbar MaliAudumbar Mali
Peripheral Nervous System,
Types of PNS,
Spinal nerves,
Types of neuron (3 basic types),
Plexus,
Cranial nerves,
Autonomic nervous system,
Structure of Neuron,
Human Anatomy and Physiology-I,
Syllabus As per PCI,
B. Pharm-I
Unit-I, Chapter_1 Nervous System Final PPT.pptAudumbar Mali
B. Pharm. Sem:-II,
BP 201T. HUMAN ANATOMY AND PHYSIOLOGY-II (Theory),
Nervous System:
Organization of nervous system, neuron, neuroglia, classification and properties of nerve fibre, electrophysiology, action potential, nerve impulse, receptors, synapse, neurotransmitters. Central nervous system: Meninges, ventricles of brain and
cerebrospinal fluid.structure and functions of brain (cerebrum, brain stem, cerebellum), spinal cord (gross structure, functions of afferent and efferent nerve tracts,reflex activity).
The nervous system is the body's main communication system; it gathers, synthesizes, and uses data from the environment. The most basic unit of the nervous system is the neuron, which serves as both a sensor and communicator of internal and external stimuli.
The human brain controls nearly every aspect of the human body ranging from physiological functions to cognitive abilities. It functions by receiving and sending signals via neurons to different parts of the body. The human brain, just like most other mammals, has the same basic structure, but it is better developed than any other mammalian brain.
3. List the parts of the brain that were discussed in class and the .pdfarshin9
3. List the parts of the brain that were discussed in class and the basic functions for each part.
Cerebral cortex; 4 lobes frontal parietal temporal occipital
homunculus primary motor cortex primary somatosensory cortex
Basal nuclei Diencephalon; 2 parts
thalamus hypothalamus
Cerebellum
Brainstem: midbrain, pons, medulla oblongata
medulla oblongata
Limbic system
Solution
The brain consists of three main parts: 1) the forebrain 2) the midbrain and 3) the hindbrain. The
forebrain is made up of cerebrum, thalamus and hypothalamus. The midbrain is made up of
tectum and tegmentum. The hindbrain consists of cerebellum, pons and medulla.
In the human brain, the cerebrum is the largest part which is associated with higher brain
function. The cerebral cortex consists of 4 lobes which are:
1) frontal lobe: this is associated with reasoning, movement, parts of speech and emotions.
2) parietal lobe: this is associated with recognition and orientation that is perception of stimuli.
3) occipital lobe: this is associated with the visual process.
4) temporal lobe: this is associated with memory, speech, perception and recognition of auditory
stimuli.
Homunculus primary motor cortex helps the brain to monitor and control the movement of the
body. While primary somatosensory cortex receives information such as pain or pressure relayed
from the spinal cord.
Thalamus is a mass of gray matter which is situated in the forebrain and has sensory and motor
functions. It carries all the sensory information via neurons to the cortex.
Hypothalamus controls the function of homeostasis, thirst, hunger, emotions, autonomic nervous
system and circadian rhythms.
Cerebellum regulates and coordinates the movement, posture and balance.
Brain stem is situated underneath the limbic system and is associated with basic functions such
as heartbeat, breathing, etc. The brain stem consists of midbrain, pons and medulla. The
midbrain controls the function of body movement, vision and hearing. Pons helps in the sensory
analysis and motor control and it is also associated with the movement and posture. Medulla
oblongata helps in maintaining the body functions such as heartbeat and breathing.
Limbic system consists of thalamus, hypothalamus, amygdala and hippocampus. Amygdala is
associated with memory, emotion and fear. Hippocampus is involved in learning and memory..
Psychobiologist study the evolutionary and physiological mechanisms that are responsible for human behavior and try to understand how the brain functions in order to understand why humans behave the way we do.
It talks about nervous system and brain behavior. This include discussion about brain, different aspects of human behavior and thought such us cental core, limbic system and cerebral cortex. Also, it discusses what consists od central core (brainstem, thalamus and cerebellum).
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
4. Midbrain
• Reticular formation: the
“traffic cops” of the brain.
• Filters sensory input, which
allows us to concentrate.
• Filtering can be affected by
higher thoughts.
5. Forebrain
• Thalamus: relay station
channeling sensory
information.
• Limbic system: basic
emotions, drives, and
behaviors.
• Cortex: higher thought
6. Limbic system
• Hypothalamus: master
controller of the endocrine
system.
• Amygdala: sensations of
pleasure or fear, recognition
of fear in others.
• Hippocampus: formation of
memories.
7. Cortex
• Various areas control
sensory processing,
motor control, thought,
memory.
• Wiring is plastic: people
blind from birth, for
example, use parts of the
visual cortex to process
auditory signals.
8. Cerebrum
• The largest portion of the brain is the
cerebrum.
• It consists of two hemispheres that are
connected together at the corpus
callosum.
• The cerebrum is often divided into
five lobes that are responsible for
different brain functions.
9. Lobes of Cerebrum
Frontal Lobe
The frontal lobe is the area of the
brain responsible for higher
cognitive functions.
These include:
• Problem solving
• Spontaneity
• Memory
• Language
• Motivation
• Judgment
• Impulse control
• Social and sexual behavior.
10. Temporal Lobe
• The temporal lobe plays a role in
emotions, and is also responsible
for:
Smelling
tasting,
Perception
Memory
understanding music
aggressiveness, and sexual
behavior.
The temporal lobe also contains the
language area of the brain.
11. Parietal Lobe
The parietal lobe plays a role in our
sensations of touch, smell, and taste.
It also processes sensory and spatial
awareness, and is a key component in
eye-hand co-ordination and arm
movement.
The parietal lobe also contains a
specialized area called Wernicke’s area
that is responsible for matching written
words with the sound of spoken speech.
12. Occipital Lobe
The occipital lobe is at the rear of the brain and controls vision and recognition
13. Limbic Lobe
The limbic lobe is located deep in the brain, and makes up the limbic system.
The limbic system is the area of the brain that regulates emotion and memory.
14. The cerebellum is connected to the brainstem, and is the center for body movement
and balance.
Cerebellum
15. Thalamus
Thalamus means “inner room” in Greek, as it sits deep in the brain at the top of the
brainstem.
Nearly all sensory inputs pass through it to the higher levels of the brain.
16. Sits under the thalamus at the top of
the brainstem.
It controls many critical bodily
functions:
autonomic nervous system
emotional response and behavior
body temperature
food intake
water balance and thirst
sleep-wake cycles
endocrine system
Hypothalamus
17. Brain Stem
Most primitive part of the brain and
controls the basic functions of life
Breathing, heart rate, swallowing,
reflexes to sight or sound, sweating,
blood pressure, sleep, and balance
18. Medulla Oblongata
The medulla oblongata merges with the
spinal cord and creates the base of the
brainstem.
The medulla is primarily a control
center for vital involuntary reflexes.
19. Pons
The pons is the rounded brainstem
region between the midbrain and the
medulla oblongata.
Major function of the pons is to
connect the cerebellum to the rest of
the brain and to modify the respiratory
output of the medulla.
20. Midbrain
• Filters sensory input, which allows us to concentrate.
• Filtering can be affected by higher thoughts.
21. Cranial Nerves
I. Olfactory nerve
II. Optic nerve
III. Oculomotor nerve
IV. Trochlear nerve
V. Trigeminal nerve
VI. Abducens nerve
VII. Facial nerve
VIII. Vestibulocochlear nerve
IX. Glossopharyngeal nerve
X. Vagus nerve
XI. Accessory nerve
XII. Hypoglossal nerve