The nervous system is composed of nerves and cells that carry messages between the brain and body. It has two main parts: the central nervous system containing the brain and spinal cord, and the peripheral nervous system containing nerves linking the body to the CNS. Neurons are the basic functional units and communicate chemically or electrically. The nervous system coordinates body functions through sensory input, integration in the CNS, and motor output responses.
The detail description about peripheral nervous system, neuron, its covering, types of neuron, synapses, spinal nerves, plexus, and more about cranial nerves at last not the least about somatic and autonomic nervous system. you may also find the information about types of peripheral nervous system in detail.
Peripheral Nervous System, Audumbar MaliAudumbar Mali
Peripheral Nervous System,
Types of PNS,
Spinal nerves,
Types of neuron (3 basic types),
Plexus,
Cranial nerves,
Autonomic nervous system,
Structure of Neuron,
Human Anatomy and Physiology-I,
Syllabus As per PCI,
B. Pharm-I
Introduction to nervous system, Divisions of Nervous System, Nervous System P...Shaista Jabeen
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Introduction to nervous system, Divisions of Nervous System, Nervous System Physiology
Introduction to nervous system
Divisions of Nervous System
Nervous System Physiology
DIVISIONS OF NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM
PERIPHERAL NERVOUS SYSTEM
Short Notes
ppt pdf
understanding spinal cord, its bransches, lesions, functions and anatomy.
hope to give you better knowledge of spinal cord by the end of it.
plese review ans comment for my future updates and corrections that iw ill be needing in this.
The central nervous system (CNS) is made up of the brain and spinal cord. The brain controls most body functions, including awareness, movements, sensations, thoughts, speech and memory. The spinal cord is connected to the brain at the brain stem and is covered by the vertebrae of the spine.
Neural control and coordination are fundamental aspects of the human body's functioning, orchestrating complex processes ranging from basic reflexes to intricate cognitive functions. In Class 11 Biology Neural Control and Coordination, understanding the nervous system's structure, functioning, and coordination mechanisms is crucial for gaining insights into physiological processes and behavioral responses. Let's delve into a detailed study of neural control and coordination:
For more information, visit-www.vavaclasses.com
Chemical coordination and integration are crucial processes in living organisms, including humans, facilitating communication and regulation among various body systems. In the human body, this coordination primarily occurs through the endocrine system, which comprises glands that secrete hormones. These detailed study notes will delve into the intricacies of chemical coordination and integration, covering its components, mechanisms, and significance.
For more information, visit-www.vavaclasses.com
The detail description about peripheral nervous system, neuron, its covering, types of neuron, synapses, spinal nerves, plexus, and more about cranial nerves at last not the least about somatic and autonomic nervous system. you may also find the information about types of peripheral nervous system in detail.
Peripheral Nervous System, Audumbar MaliAudumbar Mali
Peripheral Nervous System,
Types of PNS,
Spinal nerves,
Types of neuron (3 basic types),
Plexus,
Cranial nerves,
Autonomic nervous system,
Structure of Neuron,
Human Anatomy and Physiology-I,
Syllabus As per PCI,
B. Pharm-I
Introduction to nervous system, Divisions of Nervous System, Nervous System P...Shaista Jabeen
https://www.youtube.com/channel/UCrrAABI7QDRCJ1yMrQCip_w/videos
https://www.facebook.com/ShaistaJabeeen/
https://www.facebook.com/Human-Physiology-Lectures-100702741804409/
Introduction to nervous system, Divisions of Nervous System, Nervous System Physiology
Introduction to nervous system
Divisions of Nervous System
Nervous System Physiology
DIVISIONS OF NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM
PERIPHERAL NERVOUS SYSTEM
Short Notes
ppt pdf
understanding spinal cord, its bransches, lesions, functions and anatomy.
hope to give you better knowledge of spinal cord by the end of it.
plese review ans comment for my future updates and corrections that iw ill be needing in this.
The central nervous system (CNS) is made up of the brain and spinal cord. The brain controls most body functions, including awareness, movements, sensations, thoughts, speech and memory. The spinal cord is connected to the brain at the brain stem and is covered by the vertebrae of the spine.
Neural control and coordination are fundamental aspects of the human body's functioning, orchestrating complex processes ranging from basic reflexes to intricate cognitive functions. In Class 11 Biology Neural Control and Coordination, understanding the nervous system's structure, functioning, and coordination mechanisms is crucial for gaining insights into physiological processes and behavioral responses. Let's delve into a detailed study of neural control and coordination:
For more information, visit-www.vavaclasses.com
Chemical coordination and integration are crucial processes in living organisms, including humans, facilitating communication and regulation among various body systems. In the human body, this coordination primarily occurs through the endocrine system, which comprises glands that secrete hormones. These detailed study notes will delve into the intricacies of chemical coordination and integration, covering its components, mechanisms, and significance.
For more information, visit-www.vavaclasses.com
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
2. Nervous System
Nervous system is a complex network
of nerves and cells that carry messages
to and from the brain and spinal cord to
various parts of the body.
The nervous system is an organ system
that coordinates activities of muscles
(voluntary and involuntary actions),
monitors organs, constructs and
processes data received from the
senses, and initiates actions. The
nervous system is a highly integrated
3. Functions of the Nervous
System
The primary function of the nervous
system is to coordinate and control
the various body functions.
The nervous system has three
overlapping functions based on the:
1. Sensory input.
2. Integration.
3. Motor output.
4. Functions of the Nervous
System
Sensory Input
◦ Monitoring stimuli occurring inside &
outside the body.
◦ Gathers information from sensory
receptors.
Integration
◦ Processes and interprets sensory input.
Motor Output
◦ Response to stimuli by activating effector
organs to produce a response.
5. Divisions of the Nervous
System
In most animals, including humans,
the nervous system consists of two
parts:
1) The central nervous system (CNS)
is composed of the brain and spinal
cord.
2) The peripheral nervous system
(PNS) consists of network of nerves
(sensory, motor and intermediate)
and ganglion linking the body to the
6. Glial cells: Non-
neuronal cells that
maintain
homeostasis, form
myelin, and
provide support
and protection for
neurons in the
brain and other
parts of the
nervous system.
7.
8. Mechanism of the Nervous
System
In the PNS, sensory receptor neurons
respond to physical stimuli in our
environment, like touch or
temperature, and send signals that
inform the CNS of the state of the
body and the external environment.
This sensory information is then
processed by the CNS, predominantly
by the brain.
9.
10. Neurons
Neurons (also called nerve cells) are the
fundamental units of the brain and nervous
system. They are able to communicate with
other cells by chemical or electrical means at
synapses.
Neuronal function is supported by
neuroglia, specialized cells which provide
nutrition, mechanical support, and protection.
The cells responsible for receiving sensory
input from the external world, for sending
motor commands to our muscles, and for
transforming and relaying the electrical
signals at every step in between.
11. Structure of Neurons
Cell body (soma).
Short, branched dendrites.
Long, single axon.
Axon terminals
12. Functional Classification Of
Neuron
Sensory (afferent) neurons:
Transmit impulses toward the CNS.
Motor (efferent) neurons: Carry
impulses away from the CNS.
Interneurons (association neurons):
Shuttle signals through CNS
pathways.
14. Neuroglia
Half the volume of the nervous
system.
Special supporting tissues.
Many types of neuroglia in CNS and
PNS.
15.
16.
17. Subdivisions of the Nervous
System
The nervous system is often divided into
components:
Gray matter: A major component of the
central nervous system, consisting of
neuronal cell bodies, dendrites and
unmyelinated axons, glial cells (astroglia
and oligodendrocytes), and capillaries.
White matter: A region of the central
nervous system containing myelinated
nerve fibers and no dendrites mainly
composed of axons.
18. Subdivisions of the Nervous
System
Gray Matter: Mostly cell bodies.
◦ Dendrites & terminals.
◦ Spinal reflex integrating center.
White Matter:
◦ Bundles of myelinated axons.
Ascending tracts – sensory.
Descending tracts – motor.
◦ Dorsal roots.
◦ Ventral roots.