This document provides information about HIV and AIDS. It begins with defining HIV as a virus that causes immunosuppression and discussing its classification. It then distinguishes between HIV and AIDS, noting that AIDS is the final stage of HIV infection. Several key points about HIV/AIDS are summarized, including that it primarily affects young adults, transmission occurs through risky behaviors, and prevention is most effective and cheaper than treatment which has no cure. Statistics on global prevalence are also presented.
A Presentation Presented To orient about HIV, AIDS and STIs for Development of Knowledge, Attitude, and Practice for Prevention of HIV and STIs for College Students.
A Presentation Presented To orient about HIV, AIDS and STIs for Development of Knowledge, Attitude, and Practice for Prevention of HIV and STIs for College Students.
What’s HIV and AIDS ?
Difference between HIV and AIDS ?
Progression of HIV and AIDS.
Transmission of HIV.
Antiretroviral Therapy.
Testing for HIV Infection.
To know about Epidemiology of HIV, Introduction of HIV, Global situation of hiv, Risk factor of hiv, Sign symptoms of hiv, prevention of hiv, treatment of hiv, National strategy for the prevention & control of HIV/AIDS in Bangladesh, Mood of transmission of hiv, lab diagnosis, definition of HIV
This is an informative, illustrated presentation about the causes, symptoms, treatment and prevention of HIV AIDS. Gives relevant data, facts and statistics about the disease updated to the most recent 2010 data.
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS),a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
Antiretroviral Resistance in HIV-1 Patients at a Tertiary Medical Institute in Saudi Arabia: a Retrospective Study and Analysis.
Journal Club,
Virology Rotation , 1/5/2019
Cryptococcal meningitis is a serious opportunistic fungal infection which occur most in severe immunocompromised patients caused by pathogenic yeast species of the cryptococcus genus called Cryptococcus neoformans which spreads from the lungs to the brain
It is the most common central nervous system (CNS) fungal infection, affecting individual with weaken body immune system
The condition is rare in healthy person
Immunosupression resulting from HIV, places a patient at risk for infection from different organisms that are other wise relatively mildly hazardaus and that would normally be cleared by a competent immune system,
The other oppotunistics diseases includes,
-Pneumocystis jirovecii pneumonia
-Toxoplasmosis
-Cytomegalovirus infections
-Tuberculosis
-Disseminated mycobacterium avium complex
Globally, approximately 957,900 cases of cryptococcal meningitis occur annually, resulting in 624,700 deaths within 3 months of infection in HIV-infected adults and children.
Cryptococcal meningitis associated with HIV infection is responsible for more than 600,000 deaths per year worldwide
In sub-Saharan Africa, 15%-30% of all patients with AIDS develop cryptococcal disease
Mortality rate of is 20%, 55%, 70% in high income , low and middle income and sub- saharan africa countries respectively
In Tanzania it accounts btn 13%- 44% of death of HIV infected individual, it is more common in male children than female
Risk factors;
Advanced HIV /AIDS
Cirrhosis
Solid organ transplantation
Systemic lupus erythematous
Advanced Malignant eg leukemia, lyphoma
Sarcoidosis
Diabetes
Long term use of corticosteroid
Disseminated Cryptococcus neoformans infection begins in the lungs by inhalation of spores, which in nature are dry, minimally capsulated and easily aerosolized
Primary pulmonary infection is self limiting
In immunocompitent patients the isolated pulmonary lesion usually heal spontaneously without disseminating even without ant fungal therapy
In immunocompromised patients cryptococcus may disseminate frequently through blood stream to other parts of the body but preferentially the central nervous system (brain and meninges) causing cryptococcal meningoencephalitis where by typically manifestating as microscopic multifocal intra cerebral lesions may be evident
The infection is more properly characterized as "meningoencephalitis" rather than meningitis since the brain parenchyma is almost always involved on histologic examination
Although pulmonary involvement is rarely dangerous , cryptococcal meningitis is life threatening and requires aggressive therapy
Focal sites of dissemination may also occur in skin, end of long bone, joints, liver, spleen, kidney, prostate, and other tissues
All these cause few or no symptoms but rarely , pyelonephritis with renal pappillary necrosis
If tissue involved typically contain cystic masses of yeast with or without inflammatory changes
Drugs
Amphotericin B
Flucytosine and Fluconazole
What’s HIV and AIDS ?
Difference between HIV and AIDS ?
Progression of HIV and AIDS.
Transmission of HIV.
Antiretroviral Therapy.
Testing for HIV Infection.
To know about Epidemiology of HIV, Introduction of HIV, Global situation of hiv, Risk factor of hiv, Sign symptoms of hiv, prevention of hiv, treatment of hiv, National strategy for the prevention & control of HIV/AIDS in Bangladesh, Mood of transmission of hiv, lab diagnosis, definition of HIV
This is an informative, illustrated presentation about the causes, symptoms, treatment and prevention of HIV AIDS. Gives relevant data, facts and statistics about the disease updated to the most recent 2010 data.
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS),a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
Antiretroviral Resistance in HIV-1 Patients at a Tertiary Medical Institute in Saudi Arabia: a Retrospective Study and Analysis.
Journal Club,
Virology Rotation , 1/5/2019
Cryptococcal meningitis is a serious opportunistic fungal infection which occur most in severe immunocompromised patients caused by pathogenic yeast species of the cryptococcus genus called Cryptococcus neoformans which spreads from the lungs to the brain
It is the most common central nervous system (CNS) fungal infection, affecting individual with weaken body immune system
The condition is rare in healthy person
Immunosupression resulting from HIV, places a patient at risk for infection from different organisms that are other wise relatively mildly hazardaus and that would normally be cleared by a competent immune system,
The other oppotunistics diseases includes,
-Pneumocystis jirovecii pneumonia
-Toxoplasmosis
-Cytomegalovirus infections
-Tuberculosis
-Disseminated mycobacterium avium complex
Globally, approximately 957,900 cases of cryptococcal meningitis occur annually, resulting in 624,700 deaths within 3 months of infection in HIV-infected adults and children.
Cryptococcal meningitis associated with HIV infection is responsible for more than 600,000 deaths per year worldwide
In sub-Saharan Africa, 15%-30% of all patients with AIDS develop cryptococcal disease
Mortality rate of is 20%, 55%, 70% in high income , low and middle income and sub- saharan africa countries respectively
In Tanzania it accounts btn 13%- 44% of death of HIV infected individual, it is more common in male children than female
Risk factors;
Advanced HIV /AIDS
Cirrhosis
Solid organ transplantation
Systemic lupus erythematous
Advanced Malignant eg leukemia, lyphoma
Sarcoidosis
Diabetes
Long term use of corticosteroid
Disseminated Cryptococcus neoformans infection begins in the lungs by inhalation of spores, which in nature are dry, minimally capsulated and easily aerosolized
Primary pulmonary infection is self limiting
In immunocompitent patients the isolated pulmonary lesion usually heal spontaneously without disseminating even without ant fungal therapy
In immunocompromised patients cryptococcus may disseminate frequently through blood stream to other parts of the body but preferentially the central nervous system (brain and meninges) causing cryptococcal meningoencephalitis where by typically manifestating as microscopic multifocal intra cerebral lesions may be evident
The infection is more properly characterized as "meningoencephalitis" rather than meningitis since the brain parenchyma is almost always involved on histologic examination
Although pulmonary involvement is rarely dangerous , cryptococcal meningitis is life threatening and requires aggressive therapy
Focal sites of dissemination may also occur in skin, end of long bone, joints, liver, spleen, kidney, prostate, and other tissues
All these cause few or no symptoms but rarely , pyelonephritis with renal pappillary necrosis
If tissue involved typically contain cystic masses of yeast with or without inflammatory changes
Drugs
Amphotericin B
Flucytosine and Fluconazole
Presentation on HIV/AIDS, public health concern- include cause, symptoms, prevention and appropriate interventions. Also it include the Epidemiological Triangle link between agent, host and environment, Status of the disease in Nepal and in world.
HIV (Human Immunodeficiency Virus) infects cells of the immune system and destroys or impairs their function.
Infection progressive deterioration of the immune system breaking down the body's ability to fight out infections & diseases by opportunistic bacteria, viruses and fungi.
AIDS (Acquired Immune Deficiency Syndrome) refers to the most advanced stages of HIV infection and a collection of signs and symptoms caused by more than 20 opportunistic infections or related cancers.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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2. A virus known as the Human
Immuno-Deficiency Virus
It causes disruption of immunity or
body defense mechanism
3. HIV vs. AIDS
Retrovirus->Lentivirus
Lentivirus->Slow Virus->Takes long
time to develop symptoms
HIV-1 (8-15 Yrs)
HIV-2 (20-30 Yrs)
4.
5. •No
•HIV is a virus and AIDS is the terminal stage of
HIV infection
•All AIDS cases are HIV infected but not all HIV
infected people have AIDS
6. Affects mostly young adults in prime productive
years
Occurs not randomly, but through risk behaviour
Long period of invisibility : 9–11 years
Prevention is important & cost-effective
Life long but high treatment cost, with no cure
Non-availability of effective HIV preventive vaccine
Associated with high level of social stigma
7. •Human is the only source as well as
only host
of the infection.
•Infection spread through mixing of
Body Fluid
•Once infected – infected for life
• Age group of 15 – 49 – most vulnerable
8. HIV is transmitted through BLOOD,
SEMEN, VAGINAL FLUID, BREAST
MILK
URINE, SPUTUM, SALIVA, TEARS,
SWEAT etc do not transmit HIV
infection
12. Dynamics of HIV spread
General Population
•Married women
•Babies and Children
•Youth
•Men
High-risk Populations
•Female Sex Workers
•Men who have sex with men
•Injecting drug users
Bridge Populations
• Clients of sex workers
• Partners of IDUs
• Migrant / mobile populations
• Truck drivers
• Population in conflict
13. Sharing common toilets
Touching, Hugging ,Kissing
Insect Bites
Coughing, Sneezing
Sharing Food or Fomites
Impure water
14. Weight loss > 10% of body weight
Chronic diarrhoea > 1 month
Prolonged fever > 1 month
Persistent cough > 1 month
Generalised pruritic dermatitis
History of herpes zoster
Oro pharyngeal candidiasis
Generalised lymphadenopathy
Disseminated herpes simplex infection
15. Exponential viral replication
Widespread systemic dissemination to the brain,
spleen, distant lymph nodes, etc. (5-11 Days)
HIV makes contact with cells located within the genital mucosa
Virus is carried to regional lymph nodes (1-2 Days)
16. Dr. Luc Montagnier of Pasteur Institute of Paris-
Cause and routes of transmission of AIDS
AIDS-Formally recognized as a new Infection on
June5,1981 when Centre for Disease Control
reported 5 LA men developed unexplained
immuno deficiency
1st
AIDS case-San Fancisco man-recognized on
24th
April’1980
Patient Zero-A canadian Flight Attendant-
reportedly infected as many as 250 men
17. 1st
case-among the sex worker in Chennai in 1986
In the same year one case was reported from
Maharasthra
1987-NACP launched
By the end of 1987, 52987 people were tested out
of which 135 were tested positive and 14 were
diagnosed to have AIDS
In 1992,NACO was set up and it was decided that
SACS will be set up in 25 states and 7 Uts.
18. Total: 33.2 (30.6 – 36.1)
million
Western &
Central Europe
760 000760 000
[600 000 – 1.1 million][600 000 – 1.1 million]
Middle East & North
Africa
380 000380 000
[270 000 – 500 000][270 000 – 500 000]
Sub-Saharan Africa
22.5 million22.5 million
[20.9 – 24.3 million][20.9 – 24.3 million]
Eastern Europe
& Central Asia
1.6 million1.6 million
[1.2 – 2.1 million][1.2 – 2.1 million]
South & South-East
Asia
4.0 million4.0 million
[3.3 – 5.1 million][3.3 – 5.1 million]
Oceania
75 00075 000
[53 000 – 120 000][53 000 – 120 000]
North America
1.3 million
[480 000 – 1.9 million]
Latin America
1.6 million1.6 million
[1.4 – 1.9 million][1.4 – 1.9 million]
East Asia
800 000800 000
[620 000 – 960 000][620 000 – 960 000]
Caribbean
230 000
[210 000 – 270 000]
Adults and children
Estimated to be living with HIV, 2007
19. Estimated number of People Living with HIV/AIDS:
2.3 million (1.8—2.9 million) in 2007
Six high prevalence states contribute more than
60% of PLHA
Women constitute 39% and Children 3.8%
Estimated Adult HIV prevalence : 0.34% (0.25%-0.43%);
Males: 0.44%, Females: 0.23%
21. 156 A Category Districts
39 B Category Districts
14 Districts with HIV prevalence >
3% among ANC clinic attendees
Evidence of HIV positivity among
IDU in Punjab, WB and Orissa
Evidence of dual mode of
transmission in Manipur & Nagaland.
24. Basic Services :- ICTC, ICTC- ANC, STD Services & Condom
Promotion, HIV-TB Coordination Programme
Care, Support and Treatment : ART Centers, Link ART
Centers,
Community Care Centers , Drop in Centers
Blood Safety – Supports to Ensure safe Blood transfusion
Sentinel Surveillance – To know the current prevalence and
trend
of HIV infection in the State,
Monitoring & Evaluation - CMIS, Reporting
25. IEC, BCC - Hot line counseling, Mainstreaming, Youth
affairs, GIPA
Coordination
TI – Targeted Intervention through NGO & CBO
TSU – Technical support Unit
Training – Capacity development of Human resources
26. Early detection of HIV
Provision of basic information on modes of
transmission and
prevention of HIV/AIDS
Link people with other HIV prevention, care and
treatment
services
27. Pre-test and Post-test Counseling
Testing for HIV
ARV prophylaxis to mother-baby pairs
Counseling on infant feeding practice
Counseling on family planning
Referral for pre-ART registration and CD4 count
Post-natal follow-up of sero-reactive mothers and their exposed babies
Cotrimoxazole Prophylaxis
EID
Partner counseling
Cross referrals
Whole Blood Finger Prick test
Out Reach Activity
28. ICTCICTC
STI prevention
& treatment
Community support to
Mainstream HIV/AIDS
Early access to
medical care,
preventive therapy
other OIs and ARV
treatment
MCH services PPTCT
Access to
family planning
Counselling
For BCC &
Psychological support
Peer support from
PLHA Network Spiritual support
Material and financial
assistance
Legal services for
children and family
Access to condoms
Early management of
Opportunistic Infection
29. Known as Anti Retroviral Therapy (ART)
It suppresses HIV replication and reduces
infectivity
Improvement of clinical condition and quality
of life
Prolongation of life BUT NO CURE
Management of opportunistic infection.
(Tuberculosis – commonest)
30. Identify eligible persons with HIV/AIDS
requiring ART
Provide free ARV drugs to eligible persons
with HIV/AIDS life long
Provide counseling services for drug adherence
Educate persons on nutrition, hygiene and
prevention
Referral for specialized services or admission.
Mechanism to tracking
32. Common STIs –
Syphillis,Gonorrhoea,Chanchriod,LGV,HIV
Common presentation – genital ulcer,urethral
and vaginal discharge, swollen lymph node etc
Screening, Syndromic treatment ,contact
tracing, treatment of partners – need to be done
STI increases the risk of HIV transmission
33. Awareness campaign-through IEC campaign in
local language
Condom promotion
Risk reduction, BCC
Capacity building of the Health care personnel
Promotion of HIV screening- possibility of
setting up ICTC in PPP mode
34. Abstinence from Pre- marital & Extra marital
Sex
Be faithful to Single Partner
Condom
Step 2: Pathogenesis, Progression (Slides 5-11) - 15 minutes
Trainer’s Notes:
Use the image on the following slide to illustrate the steps involved in the pathogenesis of HIV infection.
Ask participants to quickly name the modes of HIV transmission
Reader’s Notes:
HIV transmitted through sexual activity enters the bloodstream via mucous membranes lining the vagina, rectum and mouth. Macrophages and dendritic cells on the surface of mucous membranes bind virus and shuttle it into the lymph nodes, which contain high concentrations of Helper T cells (CD4+ T cells).
Once HIV has entered the body, the immune system initiates anti-HIV antibody and cytotoxic T cell production. However, it can take one to six months for an individual exposed to HIV to produce measurable quantities of antibody. The immune response is weakened as memory T cells (CD4+ CCR5+) are destroyed.
HIV enters the body and binds to dendritic cells (orange cells with projections) which carry the virus to CD4+ T cells in lymphoid tissue establishing the infection.
Virus replication accelerates producing massive viremia and wide dissemination of virus throughout the body's lymphoid tissues.
An immune response against virus causes some protection but a chronic persistent infection is established. The production of cytokines and cell divisions that regulate the immune response for protection also cause HIV replication.
There is a rapid turnover of CD4+ T cells that ultimately leads to their destruction and to a change in lymphoid tissues that prevent immune responses.
Six states are categorized as high prevalence states, i.e. Andhra Pradesh, Karnataka, Nagaland, Manipur, Maharashtra and Tamil Nadu, since the HIV prevalence rates among women attending antenatal clinics in these states is 1 percent and above.
Gujarat, Pondicherry and Goa are categorized as states with moderate prevalence of HIV, since HIV prevalence rates amongst high risk population (STD Clinic attendees) has been found to be 5 percent or more, but among women attending ante-natal clinics, the HIV prevalence rates are below one percent.
All remaining States/Union Territories are categorized as low prevalence States since the prevalence rates amongst high-risk population (STD Clinic attendees) is below 5 percent.
However on the basis of vulnerability like migration, size of population and presence of weak health infrastructure, these states are further classified as “Highly vulnerable” and “Vulnerable” States.