This document summarizes a seminar report on HIV/AIDS presented by Ekundayo Samuel Adebowale. It outlines the structure and transmission of HIV, symptoms and diagnosis of AIDS, and treatment options. HIV is a retrovirus that infects and kills CD4 cells of the immune system, causing AIDS. Symptoms of AIDS include opportunistic infections due to a weakened immune system. Treatment involves antiretroviral drugs to suppress HIV and prevent opportunistic infections.
HIV AIDS Lecture Presented by me in my Community Dentistry Class, BIBI ASIFA DENTAL COLLEGE, SHAHEED MOHTARMA BENAZIR BHUTTO MEDICAL UNIVERSITY LARKANA, SINDH, PAKISTAN.
A Presentation Presented To orient about HIV, AIDS and STIs for Development of Knowledge, Attitude, and Practice for Prevention of HIV and STIs for College Students.
HIV AIDS Lecture Presented by me in my Community Dentistry Class, BIBI ASIFA DENTAL COLLEGE, SHAHEED MOHTARMA BENAZIR BHUTTO MEDICAL UNIVERSITY LARKANA, SINDH, PAKISTAN.
A Presentation Presented To orient about HIV, AIDS and STIs for Development of Knowledge, Attitude, and Practice for Prevention of HIV and STIs for College Students.
This slide contains information regarding HIV, ARV. This can be helpful for proficiency level and bachelor level nursing students. Your feedback is highly appreciated. Thank you!
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS),a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
HIV AIDS is one of the most dreadful of all diseases. Newer drugs and drug combination are coming quite frequently. Attempts to design an HIV vaccine is also underway.
This seminar is my attempt this interesting topic with all the latest data I could collect on the internet.
This slide contains information regarding HIV, ARV. This can be helpful for proficiency level and bachelor level nursing students. Your feedback is highly appreciated. Thank you!
Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS),a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
HIV AIDS is one of the most dreadful of all diseases. Newer drugs and drug combination are coming quite frequently. Attempts to design an HIV vaccine is also underway.
This seminar is my attempt this interesting topic with all the latest data I could collect on the internet.
This is an informative, illustrated presentation about the causes, symptoms, treatment and prevention of HIV AIDS. Gives relevant data, facts and statistics about the disease updated to the most recent 2010 data.
The theme for the 2020 observance is “Ending the HIV/AIDS Epidemic: Resilience and Impact” (“Erradicar la epidemia del VIH/SIDA: Resiliencia e Impacto”). World AIDS Day was first observed in 1988.
H: Infects only Human beings
I: Immunodeficiency Virus weakness the Immune system and increases the risk of infections
V: Virus that attacks the body and finally kills the body’s immune system
this presentation has brief about HIV, AIDS, some rough statistics of AIDS in INDIA and mechanism of HIV infection, modes of transmission, the diagnosis and treatments of AIDS.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Seminar presentation on HIV at Joseph Ayo Babalola Uni
1. A SEMINAR REPORT ON
HIV AIDS
PRESENTED BY
EKUNDAYO SAMUEL ADEBOWALE
MATRIC NO: 0903010023
DEPARTMENT OF BIOLOGICAL SCIENCES
JOSEPH AYO BABALOLA UNIVERSITY,
IKEJI-ARAKEJI,
OSUN STATE.
MARCH, 2013
2. OUTLINE
INTRODUCTION.
STRUCTURE, INFECTION AND TRANSMISSION OF HIV
SYMPTOMS, DIAGNOSIS AND PREVENTION.
INTRODUCTION AND ORIGIN AIDS.
PREVALENCE, CAUSE AND SYMPTOMS OF AIDS.
DIAGNOSIS AND TREATMENT OF AIDS.
CONCLUSION AND RECOMENDATION.
3. •HIV (Human Immunodeficiency Virus) is a
Retrovirus that causes AIDS by infecting replicating
in, and killing helper T cells (CD4 cells) of the
immune system it belongs to the family Lenitvirus
•They infect Vital cells of the immune system such
as the helper T cells. (specifically CD4 T cells),
macrophages, and dendritic cells
INTRODUCTION AND ORIGIN OF HIV
5. INFECTION
Viruses such as HIV cannot grow or
reproduce on their own, they need to
infect the cells of a living organism in
order to replicate (make new copies
of themselves).
◦ There are two types of infection
Acute infection (between 2-4 weeks post exposure)
Chronic infection (between 2 weeks and 20 years post
exposure)
6. PLATE 2: Viral particles on a cell surface
SOURCE: Encarta Dictionaries
7. Plate 3: An Immunocompromised patient
Source: www.patient.co.uk
10. Plate 5: Viral rash on skin
Plate 6: Viral rash on tongue
Source: hardinmd.lib.uiowa.ed
11. TESTING FOR HIV
There are various types of HIV test, but
the most commonly used are
The antibody or enzyme-linked
immunodeficient assay or enzyme
immunoassay also known as EIA or
ELISA test - detects HIV antibodies in a
person's blood
STRIP TEST imunochromatographic
strips, the most recent development,
potentially require only one step and
incorporate both antigen and signal
reagent into a nitrocellulose strip
12. Prevention
Preventing sexual transmission of HIV
Preventing transmission of HIV
through blood
Preventing mother to child
transmission of HIV
13. AIDS
Acquired Immunodeficiency Syndrome
AIDS is caused by HIV damaging the
immune system cells until the immune
system can no longer fight off other
infections that it would usually be able to
prevent.
It takes around ten years on average for
someone with HIV to develop AIDS.
14. Number of people living with AIDS in 2010
Total 53,700,000
Adults 30,800,000
Women 19,400,000
Children (<15 years) 3,500,000
People newly infected with HIV in 2010
Total 5,600,000
Adults 5,100,000
Children (<15 years) 500,000
AIDS deaths in 2010
Total 7,100,000
Adults 6,700,000
Children (<15 years) 400,000
All figures are estimates
Source: World Health Organization;
Joint United Nations Programme on HIV/AIDS (UNAIDS)
Table 1: Total AIDS cases around the world as at
15. CAUSES OF AIDS
There are two types of this virus: HIV-1 and
HIV 2, which are the primary cause of AIDS
◦ Inside the body HIV enters cells of the immune
system, especially white blood cells known as T
cells
◦ HIV attack are specialized “helper” T cells known
as CD4 cells. When HIV infects a CD4 cell, it
commandeers the genetic tools within the cell to
manufacture new HIV virus
◦ The loss of CD4 cells endangers health because
these cells help other types of immune cells
respond to invading organisms
16. SYMPTOMS OF AIDS
Flu-like symptoms;
◦ such as; fever, sore throat, headache,
skin rash, tender lymph nodes, and a
vague feeling of discomfort.
Opportunistic infections;
◦ such as; Pneumocystis pneumonia,
tuberculosis, viral opportunistic infections,
cancers, neurological disorders
17. DAIGNOSING AIDS
The diagnosis of AIDS can be made
by counting the CD4 cells, if it falls
below 200 cells per microliter of blood
A diagnosis of AIDS can also be made
without confirmation of CD4 levels if
someone who has no other reason for
immune system damage develops an
opportunistic disease.
19. TREATMENT contd.
Post-exposure prevention;
administering antiretroviral drugs
within 24 hours after exposure to HIV
can protect a person from becoming
infected with the virus
Development of new drugs
Treatment of opportunistic infections;
such asclarithromycin or azithromycin
to prevent Mycobacterium avium
20. Conclusion
HIV test shouldn’t be done using the
immunochromatographic strips.
Rather, the method of assay of viruses
should be used, because the virus
cannot be detected in the window
stage.