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COURSE INSTRUCTOR:
Mr. SUJIT KUMAR MOHANTY
SCIENCE & ENVIRONMENT COMMUNICATION
PRESENTATOR:
RAVI RAJESH
4TH SEMESTER
 India is a country which is quite infamous for its sanitation and
cleanliness. The chaotic waste management system and urban
planning is responsible for the overflowing gutters and scattered
waste.

The common man has to suffer a lot because of this
mismanagement. To add to the poor sanitary conditions, the
population load is increasing each day. This has resulted in slums
and poverty. The poor and unhealthy living is the primary cause for
many health disorders
What is HIV?
HIV stands for: Human Immunodeficiency Virus
HIV is a virus. Viruses such as HIV cannot grow or reproduce on their own, they need
to infect the cells of a living organism in order to replicate (make new copies of
themselves). The human immune system usually finds and kills viruses fairly quickly,
but HIV attacks the immune system itself - the very thing that would normally get
rid of a virus.
What is AIDS?
AIDS stands for: Acquired Immune Deficiency Syndrome
AIDS is a medical condition. A person is diagnosed with AIDS when their immune
system is too weak to fight off infections.
Since AIDS was first identified in the early 1980s, an unprecedented number of
people have been affected by the global AIDS epidemic. Today, there are an
estimated 35.3 million people living with HIV and AIDS worldwide.
What is the connection between HIV & AIDS?
The condition that is referred to as AIDS is caused by HIV damaging the immune
system cells until the immune system can no longer fight off other infections that it
would usually be able to prevent.
If left untreated, it takes around ten years on average for someone with HIV to
develop AIDS. However, this average is based on the person with HIV having
a reasonable diet, and someone who is malnourished may well progress from HIV to
AIDS more rapidly.
• 1986: 1st case of HIV detected in Chennai.
• 1990: HIV/AIDS Cell set up in MoHFW.
• 1992: NACP-I launched.
• 1992: National AIDS Control Organization (NACO)
established within MoHFW.
• 1999-2006: NACP-II launched.
• 2007-2012: NACP-III launched.
• NACP IV (2012-2017) on the anvil with projected
outlay of more than US$ 2 billion
A PERSONWITHAIDS
(Appearance of body)
 “Human Immunodeficiency virus”
 An specific type of virus(RNA retrovirus)
 Main causative virus of AIDS
INDIA IS RANKED 3RD IN THE WORLD. The estimated number of
people living with HIV was 2.1 million at the end of 2013 Behind
South Africa(6.3 million) and Nigeria.
 Acquired Immunodeficiency Syndrome
 Disease limits the body’s ability to fight
infection
 A person with AIDS has a very weak immune
system.
1926
Some scientists believe HIV spreaded from monkeys to humans
between 1926 - 1946.
1959
A man died in Congo, in what researchers now say was the first
proven AIDS death.
1987
The FDA approves the first antiretroviral
medication,zidovudine (AZT), as an AIDS treatment.
1978
Gay men in the U.S. and Sweden – and heterosexuals in
Tanzania and Haiti --begin showing signs of what will later
be called AIDS
Overview of HIV and AIDS in India
In india , estimated that around 2.4 million people are currently living
with HIV
 Short, flu-like illness - occurs one to six
weeks after infection
 no symptoms at all
 Infected person can infect other people
 Lasts for an average of ten years
 This stage is free from symptoms
 There may be swollen glands
 The level of HIV in the blood drops to very low
levels
 HIV antibodies are detectable in the blood
 The symptoms are mild
 The immune system deteriorates
 Emergence of opportunistic infections and
cancers
 The immune
system weakens
 The illnesses
become more
severe leading to
an AIDS diagnosis
 Bacterial
◦ Tuberculosis (TB)
◦ Strep pneumonia
 Viral
◦ Kaposi Sarcoma
◦ Herpes
◦ Influenza (flu)
 ELISA (Enzyme-Linked Immunosorbent Assay )
 Rapid or point-of-care tests
 Interpreting antibody tests
 Western blot
AIDS IS SPREAD IN THE FOLLOWING WAYS:
HIV is found
in
blood,semen,
vaginal fluids
and linings of
genital areas
2 Mother to Child
Breast
feeding
Pregnancy
Childbirth
All blood in
hospitals
(blood
transfusions)
is now tested
for HIV
3 Unprotected sex
(Sex without a
condom) oral ,
anal
or vaginal sex
1 Infected blood
(Needles, cut/sore,
razor blades,
Toothbrushes, blood
transfusion)
AIDS IS NOT SPREAD BY
Mosquito Bites Laughing Food
Hugging and
Touching
Sharing Toilets,
baths
Swimming PoolsSneezing and
Coughing
Kissing
Prevention is better than cure
Look before you leap
1) AZT (Zidovudine)
2) Viramune (Nevirapine)
3)Norvir (Ritonavir)
 Issued in an event where antiretroviral
drugs are not available
 Abstinence
 Monogamous Relationship
 Protected Sex
 Sterile needles
 If a needle/syringe or cooker is shared, it
must be disinfected:
◦ Fill the syringe with undiluted bleach and wait at
least 30 seconds.
◦ thoroughly rinse with water
◦ Do this between each person’s use
 Non-profit
Organization,
which provides
sterile needles in
exchange for
contaminated
ones
 They are still not accepted by the society.
 They are kept isolated from the society.
 They are compelled to leave the place they
belong after the society comes to know that
he/she is a victim of HIV/AIDS.
 The four high prevalence states of South India
(Andhra Pradesh – 500,000, Karnataka –
250,000, Tamil Nadu – 150,000, Maharashtra
– 420,000, ) account for 55% of all HIV
infections in the country.
 West Bengal, Gujarat, Bihar and Uttar Pradesh
are estimated to have more than 100,000
PLHA each and together account for another
22% of HIV infections in India.
Status of HIV epidemic in India
Category Estimation
Total population 1.027 billion
HIV prevalence (15-49 years) 0.34%
HIV prevalence among men (15-49
years)
0.40%
HIV prevalence among women (15-49
years)
0.27%
Number of people living with HIV (adults
and children)
2.31 million
Number of Children living with HIV (>15
years)
3.8% of total
Ravi Rajesh
Category NACP-III
A 156
B 39
C 296
D 118
New
Districts
30
Total 609
Catego
ry
NACP-III Definition
A > 1% ANC prevalence in any of the sites in
the last 3 years
B < 1% ANC prevalence in all the sites during
last 3 years with > 5% prevalence in any
HRG site (STD/FSW/MSM/IDU)
C < 1% ANC prevalence in all sites during last
3 years with < 5% in all STD clinic
attendees or any HRG, with known hot
spots
D < 1% ANC prevalence in all sites during last
3 years with < 5% in all STD clinic
attendees or any HRG OR no or poor HIV
data with no known hot spots
22.5 21.9 21.4 21.1 20.9
0.33
0.31 0.30
0.28 0.27
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.0
5.0
10.0
15.0
20.0
25.0
2007 2008 2009 2010 2011
AdultHIVPrevalence(%)
NumberofPLHIV(Lakhs)
Estimated Adult HIV Prevalence & Number of PLHIV,
India, 2007-11
Number of PLHA (Lakhs) Adult HIV Prevalence (%)
Female: 39% of PLHIV; Children: 7% of PLHIV
Source: Technical Report India HIV Estimates 2012, NACO & NIMS
6 High
Prev.
States
31%
10 Low
Prev.
States
57%
Other
12%
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
03-05 04-06 05-07 06-08 07-10
ANC HIV Prevalence (%)
Distribution of Estimated
New HIV Infections (2011)
HP-South-4
HP-NE-3
India
LP-North-7
LP-North-6
Declining trends in high prev. states of
South & North East, but still at higher levels;
Stable to rising trends in low prev. states of
Central & North India
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
0
2
4
6
8
10
12
03-05 04-06 05-07 06-08 07-10
ANCHIVPrevalence(%)
HRGHIVPrevalence(%)
ANC
MSM
FSW
IDU
Declining trends among general
population, FSW & MSM;
Stable trends among IDU
Need to sustain efforts in High
Prevalence areas to consolidate gains
www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013
Routes of HIV Transmission, 2012-13
 Several factors put India in danger of
experiencing rapid spread of HIV .
 These risk factors include:
1. Unsafe sex.
2. MSM (Men having Sex with Men).
3. IDU (Injection Drug User).
4. Migration & Mobility.
5. Low status of women.
6. Widespread stigma.
 To meet the above objectives, various
interventions were initiated with clearly
defined -
- technical and operational guidelines and
- monitoring indicators.
 The National AIDS Control Organization
(NACO) under Ministry of Health and Family
Welfare is the overall body for framing policy,
guidelines and strategies for program
implementation.
 It also releases funds to various states and
reviews the progress under various
components of the program.
 State AIDS Control Societies (SACS) have been
constituted throughout the country with the
responsibility of program implementation.
 In high HIV prevalent districts, District AIDS
Prevention Control Unit (DAPCU) has been set
up for direct supervision at the ground level.
STATUS OF
CANCER IN INDIA.
 Cancer may regarded as a group of diseases characterized by
an
◦ Abnormal growth of cells
◦ Ability to invade tissue and even distant organs
◦ The eventually death of the affected patient if the tumor
has progressed beyond the stage when it can be
successfully removed
 lung cancer
 Breast cancer
 Colon and rectal cancer
 Endometrial cancer
 Pancreatic cancer
 Kidney cancer
 Prostrate cancer
 Thyroid cancer
 Skin cancer
 There are lot of international variations in the
pattern of cancer which are attributed to a
number of factors such as
◦ environmental factors
◦ food habit
◦ lifestyle
◦ genetic factor
◦ inadequacy in detection and reporting of cases
 Tobacco
◦ Tobacco in various forms of usage can cause
cancer of lungs, larynx, mouth, pharynx,
esophagus, bladder, pancreas and probably kidney
◦ Cigarette smoking is now responsible for more than
1 million death each year
 Alcohol
◦ Excess intake of alcohol can cause esophageal and
liver cancer
◦ Beer consumption may be associated with rectal
cancer
◦ Alcohol contributes about 3 % of all cancer deaths
 Others
◦ Sunlight, radiation, water and air pollution,
medication and pesticides
◦ These are related to cancer as environmental
factors
 Dietary factor
◦ Smoked fish is related to stomach cancer
◦ Dietary fiber to intestinal cancer
◦ Beef consumption to bowel cancer
◦ High fat diet to breast cancer
◦ Food additives and contaminants have fallen under
suspicion as causative agents
 Occupational exposures
◦ These includes exposure to benzene, cadmium,
arsenic, chromium, vinyl chloride, asbestos,
polycyclic hydrocarbons, etc.
◦ The risk of occupational exposure is said to be
increased if the individual also smokes cigarette
◦ Occupational exposure is usually reported 1-5% of
human cancer
 It consists of prevention,
detection, diagnosis,
 treatment, after care and
 rehabilitation, reducing incidence and
prevalence
 Primary control
◦ Reducing the exposure to the risk factors
◦ Control of Tabaco and alcohol consumption
 Control of these two will reduce the total burden of
cancer by 1 million cases per year
 The four most common cancer in India are
 Male-oropharynx, esophagus, stomach and
lower respiratory tract
 Female-breast, cervix, oropharynx and
esophagus
 Tabaco is used widely used in India
 91% cases of oropharynx is due to Tabaco
use
 60% cases in female are breast, cervix and
ovary cancer
 Early cancer no symptoms
 Change in bowel habits or bladder functions
 Sores that do not heal
 Unusual bleeding or discharge
 Lumps or thickening of breast or other parts of the
body
 Indigestion or difficulty swallowing
 Recent change in wart or mole
 Persistent coughing or hoarseness
 Screening
 Self examinations
 Biopsy
 X-rays, CT scans, MRI scans, PET scans, and
ultrasound scans
 Molecular diagnostic test
 Surgery
 Radiotherapy
 Chemotherapy
 Immunotherapy
 Hormone therapy
 Gene therapy
 Cancer-specific immune system cells to treat cancer
EPIDEMOLOGY OF CANCER
CANCER CAUSES IN DEVELOPED AND DEVELOPING
ECONOMIES
Cancer scenario in India
Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]
STATEWISE DEPICTION OF CANCER IN INDIA
ETIOLOGICAL FACTORS FOR DIFFERENT CANCERS IN INDIA
SMOKING & HOOKAH
BIDI & HOOKAH SMOKING
SMOKED MEAT,TOBACCO,
HOOKAH
BETEL NUT,
PANMASALA, ALCOHOL
BETEL CHEWING
PAN MASALAAND ALCOHOL
NUCLEAR POLLUTION
AIR POLLUTION
PAN MASALA & GUTKA
TOBACCO USE IN DIFFERENT FORM
TUIBUR
GALL STONES
 2020- 10 million deaths,70% in developing countries (
Murray et al,1996)
 Incidence in India less than developed countries
(Fenley ,2001)
 Lung cancer worldwide 14%,all of India
6.8%(Nandakumar,2001)
 South east Asian countries including India, lower rates
of stomach cancer (Parkin et al,1999,WHO,2001),
Mizoram shows increased no cases ( Hadjiiski et al,
2006)
Comparison of cancer; Indian scenario with USA [Fenley et al, 2001]
 Worryingly, many people think there is a 'cure' for HIV, the virus
that causes AIDS - which perhaps makes them take risks that
they otherwise wouldn't. However, there is still no cure for HIV.
The only way to ensure that you avoid AIDS is to be aware
of how HIV is transmitted and how to prevent HIV infection
Increase in the no: of cancer patients every year
 Factors responsible should be controlled
 Create awareness about cancer and its prevention
 Careful about diet and lifestyle
 Slideshare.
 Wikipidea,
 http://www.avert.org/india-hiv-aids-statistics.html
 All about cancer http://www.medicalnewstoday.com/info/cancer-oncology/
 Imran Ali,Waseem A. Wani and Kishwar Saleem,( 2011)Cancer Scenario in India
with Future Perspectives, Cancer Therapy Vol 8, 56-70
 National cancer institute, http://www.cancer.gov/
 Gobal cancer facts and figures,
http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/d
ocument/acspc-027766.pdf
THANK
YOU

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Major Health Issues in India: HIV/AIDS & CANCER IN INDIA...

  • 1.
  • 2. COURSE INSTRUCTOR: Mr. SUJIT KUMAR MOHANTY SCIENCE & ENVIRONMENT COMMUNICATION PRESENTATOR: RAVI RAJESH 4TH SEMESTER
  • 3.  India is a country which is quite infamous for its sanitation and cleanliness. The chaotic waste management system and urban planning is responsible for the overflowing gutters and scattered waste.  The common man has to suffer a lot because of this mismanagement. To add to the poor sanitary conditions, the population load is increasing each day. This has resulted in slums and poverty. The poor and unhealthy living is the primary cause for many health disorders
  • 4.
  • 5. What is HIV? HIV stands for: Human Immunodeficiency Virus HIV is a virus. Viruses such as HIV cannot grow or reproduce on their own, they need to infect the cells of a living organism in order to replicate (make new copies of themselves). The human immune system usually finds and kills viruses fairly quickly, but HIV attacks the immune system itself - the very thing that would normally get rid of a virus. What is AIDS? AIDS stands for: Acquired Immune Deficiency Syndrome AIDS is a medical condition. A person is diagnosed with AIDS when their immune system is too weak to fight off infections. Since AIDS was first identified in the early 1980s, an unprecedented number of people have been affected by the global AIDS epidemic. Today, there are an estimated 35.3 million people living with HIV and AIDS worldwide. What is the connection between HIV & AIDS? The condition that is referred to as AIDS is caused by HIV damaging the immune system cells until the immune system can no longer fight off other infections that it would usually be able to prevent. If left untreated, it takes around ten years on average for someone with HIV to develop AIDS. However, this average is based on the person with HIV having a reasonable diet, and someone who is malnourished may well progress from HIV to AIDS more rapidly.
  • 6. • 1986: 1st case of HIV detected in Chennai. • 1990: HIV/AIDS Cell set up in MoHFW. • 1992: NACP-I launched. • 1992: National AIDS Control Organization (NACO) established within MoHFW. • 1999-2006: NACP-II launched. • 2007-2012: NACP-III launched. • NACP IV (2012-2017) on the anvil with projected outlay of more than US$ 2 billion
  • 8.  “Human Immunodeficiency virus”  An specific type of virus(RNA retrovirus)  Main causative virus of AIDS INDIA IS RANKED 3RD IN THE WORLD. The estimated number of people living with HIV was 2.1 million at the end of 2013 Behind South Africa(6.3 million) and Nigeria.
  • 9.  Acquired Immunodeficiency Syndrome  Disease limits the body’s ability to fight infection  A person with AIDS has a very weak immune system.
  • 10. 1926 Some scientists believe HIV spreaded from monkeys to humans between 1926 - 1946. 1959 A man died in Congo, in what researchers now say was the first proven AIDS death.
  • 11. 1987 The FDA approves the first antiretroviral medication,zidovudine (AZT), as an AIDS treatment. 1978 Gay men in the U.S. and Sweden – and heterosexuals in Tanzania and Haiti --begin showing signs of what will later be called AIDS
  • 12.
  • 13. Overview of HIV and AIDS in India In india , estimated that around 2.4 million people are currently living with HIV
  • 14.
  • 15.  Short, flu-like illness - occurs one to six weeks after infection  no symptoms at all  Infected person can infect other people
  • 16.  Lasts for an average of ten years  This stage is free from symptoms  There may be swollen glands  The level of HIV in the blood drops to very low levels  HIV antibodies are detectable in the blood
  • 17.  The symptoms are mild  The immune system deteriorates  Emergence of opportunistic infections and cancers
  • 18.  The immune system weakens  The illnesses become more severe leading to an AIDS diagnosis
  • 19.  Bacterial ◦ Tuberculosis (TB) ◦ Strep pneumonia  Viral ◦ Kaposi Sarcoma ◦ Herpes ◦ Influenza (flu)
  • 20.  ELISA (Enzyme-Linked Immunosorbent Assay )  Rapid or point-of-care tests  Interpreting antibody tests  Western blot
  • 21. AIDS IS SPREAD IN THE FOLLOWING WAYS: HIV is found in blood,semen, vaginal fluids and linings of genital areas 2 Mother to Child Breast feeding Pregnancy Childbirth All blood in hospitals (blood transfusions) is now tested for HIV 3 Unprotected sex (Sex without a condom) oral , anal or vaginal sex 1 Infected blood (Needles, cut/sore, razor blades, Toothbrushes, blood transfusion)
  • 22. AIDS IS NOT SPREAD BY Mosquito Bites Laughing Food Hugging and Touching Sharing Toilets, baths Swimming PoolsSneezing and Coughing Kissing
  • 23. Prevention is better than cure Look before you leap
  • 24. 1) AZT (Zidovudine) 2) Viramune (Nevirapine) 3)Norvir (Ritonavir)
  • 25.  Issued in an event where antiretroviral drugs are not available
  • 26.  Abstinence  Monogamous Relationship  Protected Sex  Sterile needles
  • 27.
  • 28.  If a needle/syringe or cooker is shared, it must be disinfected: ◦ Fill the syringe with undiluted bleach and wait at least 30 seconds. ◦ thoroughly rinse with water ◦ Do this between each person’s use
  • 29.  Non-profit Organization, which provides sterile needles in exchange for contaminated ones
  • 30.  They are still not accepted by the society.  They are kept isolated from the society.  They are compelled to leave the place they belong after the society comes to know that he/she is a victim of HIV/AIDS.
  • 31.  The four high prevalence states of South India (Andhra Pradesh – 500,000, Karnataka – 250,000, Tamil Nadu – 150,000, Maharashtra – 420,000, ) account for 55% of all HIV infections in the country.  West Bengal, Gujarat, Bihar and Uttar Pradesh are estimated to have more than 100,000 PLHA each and together account for another 22% of HIV infections in India.
  • 32. Status of HIV epidemic in India
  • 33. Category Estimation Total population 1.027 billion HIV prevalence (15-49 years) 0.34% HIV prevalence among men (15-49 years) 0.40% HIV prevalence among women (15-49 years) 0.27% Number of people living with HIV (adults and children) 2.31 million Number of Children living with HIV (>15 years) 3.8% of total Ravi Rajesh
  • 34. Category NACP-III A 156 B 39 C 296 D 118 New Districts 30 Total 609 Catego ry NACP-III Definition A > 1% ANC prevalence in any of the sites in the last 3 years B < 1% ANC prevalence in all the sites during last 3 years with > 5% prevalence in any HRG site (STD/FSW/MSM/IDU) C < 1% ANC prevalence in all sites during last 3 years with < 5% in all STD clinic attendees or any HRG, with known hot spots D < 1% ANC prevalence in all sites during last 3 years with < 5% in all STD clinic attendees or any HRG OR no or poor HIV data with no known hot spots
  • 35. 22.5 21.9 21.4 21.1 20.9 0.33 0.31 0.30 0.28 0.27 0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 0.0 5.0 10.0 15.0 20.0 25.0 2007 2008 2009 2010 2011 AdultHIVPrevalence(%) NumberofPLHIV(Lakhs) Estimated Adult HIV Prevalence & Number of PLHIV, India, 2007-11 Number of PLHA (Lakhs) Adult HIV Prevalence (%) Female: 39% of PLHIV; Children: 7% of PLHIV Source: Technical Report India HIV Estimates 2012, NACO & NIMS
  • 36. 6 High Prev. States 31% 10 Low Prev. States 57% Other 12% 0 0.2 0.4 0.6 0.8 1 1.2 1.4 1.6 03-05 04-06 05-07 06-08 07-10 ANC HIV Prevalence (%) Distribution of Estimated New HIV Infections (2011) HP-South-4 HP-NE-3 India LP-North-7 LP-North-6 Declining trends in high prev. states of South & North East, but still at higher levels; Stable to rising trends in low prev. states of Central & North India
  • 37. 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 0 2 4 6 8 10 12 03-05 04-06 05-07 06-08 07-10 ANCHIVPrevalence(%) HRGHIVPrevalence(%) ANC MSM FSW IDU Declining trends among general population, FSW & MSM; Stable trends among IDU Need to sustain efforts in High Prevalence areas to consolidate gains
  • 38. www.ias2013.org Kuala Lumpur, Malaysia , 30 June - 3 July 2013 Routes of HIV Transmission, 2012-13
  • 39.  Several factors put India in danger of experiencing rapid spread of HIV .  These risk factors include: 1. Unsafe sex. 2. MSM (Men having Sex with Men). 3. IDU (Injection Drug User). 4. Migration & Mobility. 5. Low status of women. 6. Widespread stigma.
  • 40.  To meet the above objectives, various interventions were initiated with clearly defined - - technical and operational guidelines and - monitoring indicators.
  • 41.  The National AIDS Control Organization (NACO) under Ministry of Health and Family Welfare is the overall body for framing policy, guidelines and strategies for program implementation.  It also releases funds to various states and reviews the progress under various components of the program.
  • 42.  State AIDS Control Societies (SACS) have been constituted throughout the country with the responsibility of program implementation.  In high HIV prevalent districts, District AIDS Prevention Control Unit (DAPCU) has been set up for direct supervision at the ground level.
  • 43.
  • 44.
  • 46.
  • 47.  Cancer may regarded as a group of diseases characterized by an ◦ Abnormal growth of cells ◦ Ability to invade tissue and even distant organs ◦ The eventually death of the affected patient if the tumor has progressed beyond the stage when it can be successfully removed
  • 48.
  • 49.  lung cancer  Breast cancer  Colon and rectal cancer  Endometrial cancer  Pancreatic cancer  Kidney cancer  Prostrate cancer  Thyroid cancer  Skin cancer
  • 50.  There are lot of international variations in the pattern of cancer which are attributed to a number of factors such as ◦ environmental factors ◦ food habit ◦ lifestyle ◦ genetic factor ◦ inadequacy in detection and reporting of cases
  • 51.  Tobacco ◦ Tobacco in various forms of usage can cause cancer of lungs, larynx, mouth, pharynx, esophagus, bladder, pancreas and probably kidney ◦ Cigarette smoking is now responsible for more than 1 million death each year  Alcohol ◦ Excess intake of alcohol can cause esophageal and liver cancer ◦ Beer consumption may be associated with rectal cancer ◦ Alcohol contributes about 3 % of all cancer deaths
  • 52.  Others ◦ Sunlight, radiation, water and air pollution, medication and pesticides ◦ These are related to cancer as environmental factors  Dietary factor ◦ Smoked fish is related to stomach cancer ◦ Dietary fiber to intestinal cancer ◦ Beef consumption to bowel cancer ◦ High fat diet to breast cancer ◦ Food additives and contaminants have fallen under suspicion as causative agents
  • 53.  Occupational exposures ◦ These includes exposure to benzene, cadmium, arsenic, chromium, vinyl chloride, asbestos, polycyclic hydrocarbons, etc. ◦ The risk of occupational exposure is said to be increased if the individual also smokes cigarette ◦ Occupational exposure is usually reported 1-5% of human cancer
  • 54.  It consists of prevention, detection, diagnosis,  treatment, after care and  rehabilitation, reducing incidence and prevalence  Primary control ◦ Reducing the exposure to the risk factors ◦ Control of Tabaco and alcohol consumption  Control of these two will reduce the total burden of cancer by 1 million cases per year
  • 55.  The four most common cancer in India are  Male-oropharynx, esophagus, stomach and lower respiratory tract  Female-breast, cervix, oropharynx and esophagus  Tabaco is used widely used in India  91% cases of oropharynx is due to Tabaco use  60% cases in female are breast, cervix and ovary cancer
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.  Early cancer no symptoms  Change in bowel habits or bladder functions  Sores that do not heal  Unusual bleeding or discharge  Lumps or thickening of breast or other parts of the body  Indigestion or difficulty swallowing  Recent change in wart or mole  Persistent coughing or hoarseness
  • 61.  Screening  Self examinations  Biopsy  X-rays, CT scans, MRI scans, PET scans, and ultrasound scans  Molecular diagnostic test
  • 62.  Surgery  Radiotherapy  Chemotherapy  Immunotherapy  Hormone therapy  Gene therapy  Cancer-specific immune system cells to treat cancer
  • 64. CANCER CAUSES IN DEVELOPED AND DEVELOPING ECONOMIES
  • 65. Cancer scenario in India Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]
  • 66. STATEWISE DEPICTION OF CANCER IN INDIA
  • 67. ETIOLOGICAL FACTORS FOR DIFFERENT CANCERS IN INDIA SMOKING & HOOKAH BIDI & HOOKAH SMOKING SMOKED MEAT,TOBACCO, HOOKAH BETEL NUT, PANMASALA, ALCOHOL BETEL CHEWING PAN MASALAAND ALCOHOL NUCLEAR POLLUTION AIR POLLUTION PAN MASALA & GUTKA TOBACCO USE IN DIFFERENT FORM TUIBUR GALL STONES
  • 68.  2020- 10 million deaths,70% in developing countries ( Murray et al,1996)  Incidence in India less than developed countries (Fenley ,2001)  Lung cancer worldwide 14%,all of India 6.8%(Nandakumar,2001)  South east Asian countries including India, lower rates of stomach cancer (Parkin et al,1999,WHO,2001), Mizoram shows increased no cases ( Hadjiiski et al, 2006)
  • 69. Comparison of cancer; Indian scenario with USA [Fenley et al, 2001]
  • 70.  Worryingly, many people think there is a 'cure' for HIV, the virus that causes AIDS - which perhaps makes them take risks that they otherwise wouldn't. However, there is still no cure for HIV. The only way to ensure that you avoid AIDS is to be aware of how HIV is transmitted and how to prevent HIV infection Increase in the no: of cancer patients every year  Factors responsible should be controlled  Create awareness about cancer and its prevention  Careful about diet and lifestyle
  • 71.
  • 72.
  • 73.  Slideshare.  Wikipidea,  http://www.avert.org/india-hiv-aids-statistics.html  All about cancer http://www.medicalnewstoday.com/info/cancer-oncology/  Imran Ali,Waseem A. Wani and Kishwar Saleem,( 2011)Cancer Scenario in India with Future Perspectives, Cancer Therapy Vol 8, 56-70  National cancer institute, http://www.cancer.gov/  Gobal cancer facts and figures, http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/d ocument/acspc-027766.pdf