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Screening
• screening test should be able to quickly
identify a health problem for which a
prevention or treatment is available.
Vision screening
• Vision screening is an efficient and cost-
effective method to identify children with
visual impairment or eye conditions that are
likely to lead to visual impairment so that a
referral can be made to an appropriate eye
care professional for further evaluation and
treatment.
The Importance of Pediatric Vision Screening
• Amblyopia affects up to 5% of the
population (>10 million Americans).
• In the first 4 decades of life amblyopia
causes more vision loss than all other
ocular diseases combined!
• Amblyopia has a “window period” for treatment
in early childhood.
• Screening can prevent otherwise fatal disorders
such as retinoblastoma.
Vision Screening: Scope of Problem
Only 21% of preschool children and even fewer
children below preschool age are screened for
these conditions.
Ottar WL, Scott WE, Holgado SI. Photoscreening for amblyogenic factors. J Pediatr Ophthalmol Strabismus. 1995;32(5):289–295
Amblyopia is Very Cost-Effective to Treat
• Membrano, et al: Cost/QALY $2,281 for
Amblyopia Tx
• Comparisons:
– Hypertension screening/therapy in asymptomatic
49 yo = $25,000/QALY
– Annual screening for Diabetic Retinopathy in high
risk diabetics = $41,700/QALY
Pediatricians Are the Natural First
Line of Defense – The Medical
Home
• Children already come to Pediatrician.
• Vaccinations and screening are
already a part of care protocol.
• Screening in pediatrics should be
most cost effective (no separate office
visit, no extra-time off work for parent).
6
AAP Policy on Vision Screening
• AAP in concert with AAO and AAPOS have a
joint policy statement recommending
screening beginning at birth and throughout
childhood during well child visit.
– Serial screening in the MEDICAL HOME
• Ensures age-appropriate monitoring of visual system.
• Is more efficient and cost effective than comprehensive
eye exams for asymptomatic children.
– Pediatricians are best champions for a child’s
health.
Amblyopia
The Physician sees nothing
and the Patient very little
Amblyopia…In Other Words:
• The camera (eye) is capable of taking the
picture but the computer (brain) doesn’t
recognize that there is an image.
• “Either use it or lose it!”
Children are Different
• Developing cortical connections
• Window of opportunity for diagnosis and
treatment…just like with language development
Screen for Causes of Amblyopia
• Refractive errors
• Obstruction of optical pathway (e.g. cataract
or corneal scar)
• Strabismus
• Other—anything that blocks input of
visual information to the brain
Motility Terminology
• Strabismus = ocular
misalignment
• Esotropia = eyes turn in
• Exotropia = eyes turn
out
• Hypertropia = one eye
higher than the other
When Should We Screen?
• Begin at birth and during all subsequent well
child visits.
– Think of vision screening like vaccinations!
– Different screening at different
developmental/age levels.
Periodicity Table for Screening
Periodicity Schedule for Visual System Assessment in Infants and Children
Newborn to
6 months
6 months to
12 months
1 to <3 years 3 to < 5 years 5 years and older
Ocular History x x X x x
External inspection of lids
and eyes
x x x x x
Red Reflex Testing x x x x x
Pupil examination x x x x
Ocular Motility Assessment x x x x
Instrument Based Screening x
+
x
+ *
Visual Acuity Fix and follow x x
Visual Acuity age-
appropriate optotype
assessment
x
∆
x
∆
+: Bill using CPT 99174
∆: Bill using CPT 99173
*: If unable to test visual acuity monocularly with age appropriate linear optotypes, instrument-based screening is suggested.
Age Specific Screening: NEWBORN
• External evaluation for obvious ocular
malformations and infections
– NOTE: Too young to evaluate alignment!!!
• RED REFLEX TEST—preferably prior to
discharge from newborn nursery
– Very important to r/o retinoblastoma or
congenital cataracts
• If congenital cataracts not removed in first 2 to 3
months of life, permanent loss of sight occurs
Bruckner Reflex
Leukocoria is an Urgency!
 Diff Dx include cataract, glaucoma, PHPV,
Retinoblastoma, Retinal detachment, etc.
 In addition to sending a consult, CALL
ophthalmologist to make sure the patient is seen
ASAP!
Basic Techniques for Examining Children’s Eyes
• Age specific
• Start with HISTORY
– Moms are great diagnosticians!
• Common EXAM components
– Assessment of vision
– External anatomy
– Pupil function
– Motility
– Ocular fundus/Red Reflex
testing
Ocular History
• Does child appear to see well distance and
near?
• Any crossing?
• Family history of eye disorders?
• Recurrent discharge or redness?
• Extreme photophobia?
• NOT to worry about:
– “Sits close to TV a lot”
External Examination
• Are eyelids symmetric?
• Pupil symmetry?
• Any redness, inflammation, or
discharge?
• Cornea clear?
• Are the eyes aligned?
Pupil Exam
• Are the pupils round?
• Symmetric?
– If asymmetric, is it more asymmetric in dark or
light?
• Reactive to light?
Motility Assessment
• Is the pupil light
reflex central?
• Do the eyes move
fully in all
directions?
• Pseudostrabismus
vs. true strabismus
Pseudostrabismus
Vision Assessment
• Infants: Eye contact, follows face, smiles
• Toddlers: Cover each eye and follows
objects (fix and follow)
• Verbal: Visual acuity screening with
appropriate optotype (symbol/letters)
Visual Acuity (VA) Testing
• To have good VA both anterior and posterior
visual pathways must be functioning.
• VA testing is the current “gold standard.
• Should be performed at earliest possible
age.
Checking VA
The 3 common errors:
• Child peaks.
• Child memorizes.
• Examiner only projects one
letter at time (crowding
phenomenon).
AAPOS Vision Screening Kit
• Can order from:
– AAPOS:
http://www.aapos.org/a
hp/vision_screening_kit
– AAP:
http://tinyurl.aap.org/pu
b221192
What about new vision
screening technology?
New Screening Technology
• Remember in the pre-verbal child, the only
way to detect amblyopia is to indirectly
detect the risk factors.
– Refractive errors
– Media opacities
– Strabismus
Objective Screening Technology
• Photoscreening
• Automated refractors
• VEP screening
• Retinal birefringence
Photoscreening
• Similar to Bruckner Reflex.
• Exploits the red-eye one gets in
photography to help assess both alignment
and refractive error.
Hyperopia Anisometropia
Photoscreening
• Instrument-based screening is now endorsed
by the as a valid measure for screening
preschool children.
• A randomized controlled multi-centered cross
over study demonstrated photoscreening to
be superior to direct testing of visual acuity
for screening well visit children ages 3–6 in
the pediatrician office.*
• For children older than 5 years, VA testing
still preferred.
Summary
• Vision screening should begin at birth and
continue throughout well child visits.
• Vision screening is age-appropriate
– Early Red Reflex testing mandatory
– VA testing in verbal children
• Objective screening technology is effective,
improving, but needs to be reimbursed for
widespread adoption.
• Pediatricians are our best line of defense for
preventable blindness!
Additional Reading

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Screening

  • 1. Screening • screening test should be able to quickly identify a health problem for which a prevention or treatment is available.
  • 2. Vision screening • Vision screening is an efficient and cost- effective method to identify children with visual impairment or eye conditions that are likely to lead to visual impairment so that a referral can be made to an appropriate eye care professional for further evaluation and treatment.
  • 3. The Importance of Pediatric Vision Screening • Amblyopia affects up to 5% of the population (>10 million Americans). • In the first 4 decades of life amblyopia causes more vision loss than all other ocular diseases combined! • Amblyopia has a “window period” for treatment in early childhood. • Screening can prevent otherwise fatal disorders such as retinoblastoma.
  • 4. Vision Screening: Scope of Problem Only 21% of preschool children and even fewer children below preschool age are screened for these conditions. Ottar WL, Scott WE, Holgado SI. Photoscreening for amblyogenic factors. J Pediatr Ophthalmol Strabismus. 1995;32(5):289–295
  • 5. Amblyopia is Very Cost-Effective to Treat • Membrano, et al: Cost/QALY $2,281 for Amblyopia Tx • Comparisons: – Hypertension screening/therapy in asymptomatic 49 yo = $25,000/QALY – Annual screening for Diabetic Retinopathy in high risk diabetics = $41,700/QALY
  • 6. Pediatricians Are the Natural First Line of Defense – The Medical Home • Children already come to Pediatrician. • Vaccinations and screening are already a part of care protocol. • Screening in pediatrics should be most cost effective (no separate office visit, no extra-time off work for parent). 6
  • 7. AAP Policy on Vision Screening • AAP in concert with AAO and AAPOS have a joint policy statement recommending screening beginning at birth and throughout childhood during well child visit. – Serial screening in the MEDICAL HOME • Ensures age-appropriate monitoring of visual system. • Is more efficient and cost effective than comprehensive eye exams for asymptomatic children. – Pediatricians are best champions for a child’s health.
  • 8. Amblyopia The Physician sees nothing and the Patient very little
  • 9. Amblyopia…In Other Words: • The camera (eye) is capable of taking the picture but the computer (brain) doesn’t recognize that there is an image. • “Either use it or lose it!”
  • 10. Children are Different • Developing cortical connections • Window of opportunity for diagnosis and treatment…just like with language development
  • 11. Screen for Causes of Amblyopia • Refractive errors • Obstruction of optical pathway (e.g. cataract or corneal scar) • Strabismus • Other—anything that blocks input of visual information to the brain
  • 12. Motility Terminology • Strabismus = ocular misalignment • Esotropia = eyes turn in • Exotropia = eyes turn out • Hypertropia = one eye higher than the other
  • 13. When Should We Screen? • Begin at birth and during all subsequent well child visits. – Think of vision screening like vaccinations! – Different screening at different developmental/age levels.
  • 14. Periodicity Table for Screening Periodicity Schedule for Visual System Assessment in Infants and Children Newborn to 6 months 6 months to 12 months 1 to <3 years 3 to < 5 years 5 years and older Ocular History x x X x x External inspection of lids and eyes x x x x x Red Reflex Testing x x x x x Pupil examination x x x x Ocular Motility Assessment x x x x Instrument Based Screening x + x + * Visual Acuity Fix and follow x x Visual Acuity age- appropriate optotype assessment x ∆ x ∆ +: Bill using CPT 99174 ∆: Bill using CPT 99173 *: If unable to test visual acuity monocularly with age appropriate linear optotypes, instrument-based screening is suggested.
  • 15. Age Specific Screening: NEWBORN • External evaluation for obvious ocular malformations and infections – NOTE: Too young to evaluate alignment!!! • RED REFLEX TEST—preferably prior to discharge from newborn nursery – Very important to r/o retinoblastoma or congenital cataracts • If congenital cataracts not removed in first 2 to 3 months of life, permanent loss of sight occurs
  • 17. Leukocoria is an Urgency!  Diff Dx include cataract, glaucoma, PHPV, Retinoblastoma, Retinal detachment, etc.  In addition to sending a consult, CALL ophthalmologist to make sure the patient is seen ASAP!
  • 18.
  • 19. Basic Techniques for Examining Children’s Eyes • Age specific • Start with HISTORY – Moms are great diagnosticians! • Common EXAM components – Assessment of vision – External anatomy – Pupil function – Motility – Ocular fundus/Red Reflex testing
  • 20. Ocular History • Does child appear to see well distance and near? • Any crossing? • Family history of eye disorders? • Recurrent discharge or redness? • Extreme photophobia? • NOT to worry about: – “Sits close to TV a lot”
  • 21. External Examination • Are eyelids symmetric? • Pupil symmetry? • Any redness, inflammation, or discharge? • Cornea clear? • Are the eyes aligned?
  • 22. Pupil Exam • Are the pupils round? • Symmetric? – If asymmetric, is it more asymmetric in dark or light? • Reactive to light?
  • 23. Motility Assessment • Is the pupil light reflex central? • Do the eyes move fully in all directions? • Pseudostrabismus vs. true strabismus
  • 25. Vision Assessment • Infants: Eye contact, follows face, smiles • Toddlers: Cover each eye and follows objects (fix and follow) • Verbal: Visual acuity screening with appropriate optotype (symbol/letters)
  • 26. Visual Acuity (VA) Testing • To have good VA both anterior and posterior visual pathways must be functioning. • VA testing is the current “gold standard. • Should be performed at earliest possible age.
  • 27. Checking VA The 3 common errors: • Child peaks. • Child memorizes. • Examiner only projects one letter at time (crowding phenomenon).
  • 28. AAPOS Vision Screening Kit • Can order from: – AAPOS: http://www.aapos.org/a hp/vision_screening_kit – AAP: http://tinyurl.aap.org/pu b221192
  • 29. What about new vision screening technology?
  • 30. New Screening Technology • Remember in the pre-verbal child, the only way to detect amblyopia is to indirectly detect the risk factors. – Refractive errors – Media opacities – Strabismus
  • 31. Objective Screening Technology • Photoscreening • Automated refractors • VEP screening • Retinal birefringence
  • 32. Photoscreening • Similar to Bruckner Reflex. • Exploits the red-eye one gets in photography to help assess both alignment and refractive error.
  • 34. Photoscreening • Instrument-based screening is now endorsed by the as a valid measure for screening preschool children. • A randomized controlled multi-centered cross over study demonstrated photoscreening to be superior to direct testing of visual acuity for screening well visit children ages 3–6 in the pediatrician office.* • For children older than 5 years, VA testing still preferred.
  • 35. Summary • Vision screening should begin at birth and continue throughout well child visits. • Vision screening is age-appropriate – Early Red Reflex testing mandatory – VA testing in verbal children • Objective screening technology is effective, improving, but needs to be reimbursed for widespread adoption. • Pediatricians are our best line of defense for preventable blindness!