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Schistosomiasis prevalence
in Zomba, Southern Malawi
Deepa Pullanikkatil
Leadership for Environment and Development Southern and Eastern
Africa
Malawi
Introduction
• A large proportion of Malawi’s more than 13 million people live in
rural areas where major livelihood activities include subsistence
farming, irrigation and fishing.
• Therefore the villagers have contact with water, which exposes them
to schistosomes.
• In this case study, surveys and parasitological investigations were
conducted to determine the prevalence of schistosomiasis and to
explore the relationship between disease prevalence and selected
qualitative variables in five villages located in Zomba District in Lake
Chilwa Basin.
What is Bilharzia?
• Schistosomiasis (Bilharzia) is
caused by flatworms of the
genus Schistosoma.
• In Africa six species- medical
concern
• Schistosoma mansoni
• S. haematobium
Signs & Symptoms
• Pain on passing urine
• Haematuria (blood in urine)
• Persistent Abdominal pain
• Blood stained stool
• Mild anaemia and malnutrition
• Cough
• Diarrhoea
• Eosinophilia — extremely high white blood cell count.
• Fever
• Fatigue
• Hepatosplenomegaly — the enlargement of both the liver
and the spleen
Hematuria
Countries affected
Species Geographical distribution
Intestinal schistosomiasis Schistosoma mansoni
Africa, the Middle East, the
Caribbean, Brazil,
Venezuela, Suriname
Schistosoma japonicum
China, Indonesia, the
Philippines
Schistosoma mekongi
Several districts of
Cambodia and the Lao
People’s Democratic
Republic
Schistosoma guineensis
and related S. intercalatum
Rain forest areas of central
Africa
Urogenital schistosomiasis Schistosoma haematobium Africa, the Middle East
Table: Parasite species and geographical distribution of schistosomiasis (WHO
Factsheet 115, Jan 2012)
Some statistics
• At least 230 million people require treatment every
year. Schistosomiasis transmission has been
documented in 77 countries. However those at most
risk of infection are in 52 countries.
• Schistosomiais is prevalent in tropical and sub-tropical
areas, especially in poor communities without access
to safe drinking water and adequate sanitation. It is
estimated that at least 90% of those requiring
treatment for schistosomiasis live in Africa.
• Source: WHO Factsheet 115, Jan 2012.
Transmission
Through contact
with schistosome
infested water
Carrier- Water
snails
Source: FAO
Prevention & Control
• Proper use of latrine
• Wearing protective gear- boots
• Avoiding swimming in infected waters, near habitat of
snails (reeds)
• Provision of safe water (boreholes with washing slabs)
• Information, Education and Communication
• Mass Treatment in endemic areas
Our
Study
Area
Methodology
• Through the Lake Chilwa Basin Climate Change Adaptation
Programme, 65 villages and 29 schools were identified as S.
haematobium hotspot areas.
• Random number tables were used to carry out basic simple random
sampling of five villages (Mukhweya, Machemba, Masala, Lamusi I
and Maluwa) and five primary schools (Mitole, Mikundi, Khuluvi,
Nazitimbe and Muluma) from the hotspot areas.
• The surveys were conducted over a three-month period from
September to November 2011, resulting in the participation of all 483
respondents from the selected villages and primary schools.
• Simple random sampling was applied in this study mainly because of
its low cost of application, and due to little available advance
knowledge of the population.
• Data from simple random sampling tends to be free of classification
errors, in addition to producing results that are simple to interpret
under different study conditions.
• Prevalence of each group was calculated as the proportion of the sum
of moderately and severely infected people to the total number of
participants representing that group, and overall prevalence was
computed by comparing total number of infected participants to the
total sample size for this study.
• Prevalence values obtained in this study are only estimates of the
true population parameters derived from data collected from
samples. Therefore confidence intervals (CIs) at the 95% confidence
level were calculated to show how bilharzia prevalence estimates
from the samples compared with the true population prevalence.
Methodology
Results
Washing, bathing and swimming in
possibly infected waters
Children lining up for treatment.
Heights being measured to
determine dosages.
Conclusion and Recommendations
• Schistosomiasis can be cheaply treated with a single dose of the drug
Praziquantel.
• Despite the relatively low treatment costs, experiences in this
endemic study region show that the re-infection rate is high, requiring
two repeated treatments, or as frequent as every six months to lower
the prevalence of the disease (Clerinx & Van Gompel, 2011).
• Funding limitations continue to hamper treatment efforts in Malawi,
and more concerted efforts are required from all sectors to mobilise
financial resources for combating the disease.
• Evidence from this study has demonstrated that targeted treatment
interventions are urgently required, focussing on complete villages
and highly vulnerable groups such as school- going children, and
occupations associated with long hours of water contact in endemic
regions.
• Such targeted measures should be part of a holistic package of
prevalence reducing measures, including the continued exploration of
potentially important options involving biological controls of
intermediate host snails
Publication
• This study was published in the African Geographical Review
Pullanikkatil,D., Mubako,S., Phalira,W., Chiotha,S and Luhanga,M.
(2013). ‘Schistosomiasis prevalence in Zomba, Malawi’, African
Geographical Review. Routledge Vol 33; Issue I.
Study benefits
• 9005 people from targeted villages were treated for Bilharzia
• Ministry of Health now allows rural villagers to access drugs through
the schools where targeted drug administration is done. This was as a
result of this study findings. Previously rural people and out of school
youth in rural areas were left out from the targeted drug
administration done in primary schools.
Thank you

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Schistosomiasis (Bilharzia) prevalence in Zomba, Southern Malawi

  • 1. Schistosomiasis prevalence in Zomba, Southern Malawi Deepa Pullanikkatil Leadership for Environment and Development Southern and Eastern Africa Malawi
  • 2. Introduction • A large proportion of Malawi’s more than 13 million people live in rural areas where major livelihood activities include subsistence farming, irrigation and fishing. • Therefore the villagers have contact with water, which exposes them to schistosomes. • In this case study, surveys and parasitological investigations were conducted to determine the prevalence of schistosomiasis and to explore the relationship between disease prevalence and selected qualitative variables in five villages located in Zomba District in Lake Chilwa Basin.
  • 3. What is Bilharzia? • Schistosomiasis (Bilharzia) is caused by flatworms of the genus Schistosoma. • In Africa six species- medical concern • Schistosoma mansoni • S. haematobium
  • 4. Signs & Symptoms • Pain on passing urine • Haematuria (blood in urine) • Persistent Abdominal pain • Blood stained stool • Mild anaemia and malnutrition • Cough • Diarrhoea • Eosinophilia — extremely high white blood cell count. • Fever • Fatigue • Hepatosplenomegaly — the enlargement of both the liver and the spleen
  • 6. Countries affected Species Geographical distribution Intestinal schistosomiasis Schistosoma mansoni Africa, the Middle East, the Caribbean, Brazil, Venezuela, Suriname Schistosoma japonicum China, Indonesia, the Philippines Schistosoma mekongi Several districts of Cambodia and the Lao People’s Democratic Republic Schistosoma guineensis and related S. intercalatum Rain forest areas of central Africa Urogenital schistosomiasis Schistosoma haematobium Africa, the Middle East Table: Parasite species and geographical distribution of schistosomiasis (WHO Factsheet 115, Jan 2012)
  • 7. Some statistics • At least 230 million people require treatment every year. Schistosomiasis transmission has been documented in 77 countries. However those at most risk of infection are in 52 countries. • Schistosomiais is prevalent in tropical and sub-tropical areas, especially in poor communities without access to safe drinking water and adequate sanitation. It is estimated that at least 90% of those requiring treatment for schistosomiasis live in Africa. • Source: WHO Factsheet 115, Jan 2012.
  • 10. Prevention & Control • Proper use of latrine • Wearing protective gear- boots • Avoiding swimming in infected waters, near habitat of snails (reeds) • Provision of safe water (boreholes with washing slabs) • Information, Education and Communication • Mass Treatment in endemic areas
  • 12. Methodology • Through the Lake Chilwa Basin Climate Change Adaptation Programme, 65 villages and 29 schools were identified as S. haematobium hotspot areas. • Random number tables were used to carry out basic simple random sampling of five villages (Mukhweya, Machemba, Masala, Lamusi I and Maluwa) and five primary schools (Mitole, Mikundi, Khuluvi, Nazitimbe and Muluma) from the hotspot areas. • The surveys were conducted over a three-month period from September to November 2011, resulting in the participation of all 483 respondents from the selected villages and primary schools. • Simple random sampling was applied in this study mainly because of its low cost of application, and due to little available advance knowledge of the population.
  • 13. • Data from simple random sampling tends to be free of classification errors, in addition to producing results that are simple to interpret under different study conditions. • Prevalence of each group was calculated as the proportion of the sum of moderately and severely infected people to the total number of participants representing that group, and overall prevalence was computed by comparing total number of infected participants to the total sample size for this study. • Prevalence values obtained in this study are only estimates of the true population parameters derived from data collected from samples. Therefore confidence intervals (CIs) at the 95% confidence level were calculated to show how bilharzia prevalence estimates from the samples compared with the true population prevalence.
  • 16.
  • 17. Washing, bathing and swimming in possibly infected waters Children lining up for treatment. Heights being measured to determine dosages.
  • 18.
  • 19. Conclusion and Recommendations • Schistosomiasis can be cheaply treated with a single dose of the drug Praziquantel. • Despite the relatively low treatment costs, experiences in this endemic study region show that the re-infection rate is high, requiring two repeated treatments, or as frequent as every six months to lower the prevalence of the disease (Clerinx & Van Gompel, 2011). • Funding limitations continue to hamper treatment efforts in Malawi, and more concerted efforts are required from all sectors to mobilise financial resources for combating the disease.
  • 20. • Evidence from this study has demonstrated that targeted treatment interventions are urgently required, focussing on complete villages and highly vulnerable groups such as school- going children, and occupations associated with long hours of water contact in endemic regions. • Such targeted measures should be part of a holistic package of prevalence reducing measures, including the continued exploration of potentially important options involving biological controls of intermediate host snails
  • 21. Publication • This study was published in the African Geographical Review Pullanikkatil,D., Mubako,S., Phalira,W., Chiotha,S and Luhanga,M. (2013). ‘Schistosomiasis prevalence in Zomba, Malawi’, African Geographical Review. Routledge Vol 33; Issue I.
  • 22. Study benefits • 9005 people from targeted villages were treated for Bilharzia • Ministry of Health now allows rural villagers to access drugs through the schools where targeted drug administration is done. This was as a result of this study findings. Previously rural people and out of school youth in rural areas were left out from the targeted drug administration done in primary schools.