Rheumatic valvular heart disease is caused by rheumatic fever, an inflammatory response to Group A streptococcal infection. It most commonly results in mitral regurgitation or stenosis from scarring of the mitral valve. Physical exam may reveal murmurs. Echocardiography is the gold standard for assessing valve structure and function. Long-term management involves serial monitoring, medications to control symptoms, and possibly surgery for severe or symptomatic cases. Complications include heart failure, arrhythmias, embolism and infective endocarditis.