This document provides an overview of Renaissance and Mannerism painting. It discusses key characteristics like naturalism, rationalism, and idealization in Renaissance works. Major Renaissance artists like Masaccio, Botticelli, Leonardo da Vinci, Raphael, and Michelangelo are profiled. The document also describes techniques used during the Renaissance and Mannerism periods like fresco painting, oil painting, and the development of engraving. Key themes in works are also outlined like religious subjects and the growing importance of portraiture and landscape. Characteristics of Mannerism painting like surprising compositions and deformations are also summarized.