This a presentation on regulation of respiration, control of the rate of increase of the the ramp signal, control of the limiting point at which ramp suddenly ceases
The document summarizes the anatomy and physiology of the respiratory system. It describes the main functions of breathing and gas exchange. It outlines the major structures of the upper respiratory tract including the nose and paranasal sinuses, as well as the lower respiratory tract including the lungs, bronchi, and alveoli where gas exchange occurs. It also discusses some clinical conditions that can affect the respiratory system.
The respiratory tract includes the mouth, nose, pharynx, larynx, trachea, bronchi and lungs. The nose contains nasal cavities lined with hairs and mucus to warm and filter air. It connects to the nasopharynx and paranasal sinuses. The pharynx consists of the nasopharynx, oropharynx and laryngopharynx and contains the tonsils. The larynx, or voice box, contains vocal cords and cartilage that support the airway and allow for sound production. It connects to the trachea and lungs.
The respiratory system consists of an upper respiratory tract and lower respiratory tract. The upper tract includes the nose, nasal cavity, paranasal sinuses, and pharynx. The lower tract includes the larynx, trachea, bronchi, and lungs. The nose warms, moistens, and filters air and contains smell receptors. The lungs contain alveoli where gas exchange occurs between air in alveoli and blood in capillaries. Breathing involves inhalation that draws air into the lungs and exhalation that forces air out.
The human respiratory system consists of the upper and lower respiratory tract. The upper tract includes the nose, nasal cavity, sinuses, pharynx and larynx. The lower tract includes the trachea, bronchi, bronchioles and lungs. The nose warms and filters inhaled air. The lungs are the primary organs for gas exchange, extracting oxygen from inhaled air into the bloodstream and releasing carbon dioxide from the bloodstream. Respiration is controlled by respiratory centers in the brainstem which regulate the muscles of breathing.
Physiology properties of bile, composition of bile, functions of bile, functi...Vamsi kumar
This document contains information about the functions of the bile, small intestine, and large intestine. It includes summaries of the properties and composition of bile, as well as its digestive, absorptive, excretory, and other functions. It also describes the functional anatomy of the small intestine, its roles in digestion and absorption of nutrients, and how food exits into the large intestine. Finally, it outlines the absorptive, excretory, secretory, synthetic and other functions of the large intestine, including its role in forming feces and the importance of dietary fiber.
Respiration is regulated by both nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that collect sensory information and control respiratory muscles. There are four respiratory centers - the inspiratory and expiratory centers in the medulla, and the pneumotaxic and apneustic centers in the pons. The chemical mechanism involves central and peripheral chemoreceptors that detect changes in blood oxygen, carbon dioxide, and hydrogen ion levels and stimulate the respiratory centers.
The human respiratory system consists of the nose, pharynx, larynx, trachea, bronchi, lungs, and alveoli. The nose and nasal cavity warm and filter incoming air. The pharynx and larynx are passageways that lead to the trachea, which divides into the left and right bronchi and further branches into bronchioles and alveoli within the lungs. Gas exchange occurs in the alveoli, where oxygen passes into the bloodstream and carbon dioxide passes out.
1. The mechanics of breathing involve reversing pressure gradients between the alveoli and atmosphere through cyclic respiratory muscle activity to allow air flow into and out of the lungs.
2. Three important pressures in respiration are atmospheric pressure, intra-alveolar pressure, and intra-pleural pressure.
3. Lung volumes include tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume. Lung capacities include functional residual capacity, inspiratory capacity, expiratory capacity, and total lung capacity.
The document summarizes the anatomy and physiology of the respiratory system. It describes the main functions of breathing and gas exchange. It outlines the major structures of the upper respiratory tract including the nose and paranasal sinuses, as well as the lower respiratory tract including the lungs, bronchi, and alveoli where gas exchange occurs. It also discusses some clinical conditions that can affect the respiratory system.
The respiratory tract includes the mouth, nose, pharynx, larynx, trachea, bronchi and lungs. The nose contains nasal cavities lined with hairs and mucus to warm and filter air. It connects to the nasopharynx and paranasal sinuses. The pharynx consists of the nasopharynx, oropharynx and laryngopharynx and contains the tonsils. The larynx, or voice box, contains vocal cords and cartilage that support the airway and allow for sound production. It connects to the trachea and lungs.
The respiratory system consists of an upper respiratory tract and lower respiratory tract. The upper tract includes the nose, nasal cavity, paranasal sinuses, and pharynx. The lower tract includes the larynx, trachea, bronchi, and lungs. The nose warms, moistens, and filters air and contains smell receptors. The lungs contain alveoli where gas exchange occurs between air in alveoli and blood in capillaries. Breathing involves inhalation that draws air into the lungs and exhalation that forces air out.
The human respiratory system consists of the upper and lower respiratory tract. The upper tract includes the nose, nasal cavity, sinuses, pharynx and larynx. The lower tract includes the trachea, bronchi, bronchioles and lungs. The nose warms and filters inhaled air. The lungs are the primary organs for gas exchange, extracting oxygen from inhaled air into the bloodstream and releasing carbon dioxide from the bloodstream. Respiration is controlled by respiratory centers in the brainstem which regulate the muscles of breathing.
Physiology properties of bile, composition of bile, functions of bile, functi...Vamsi kumar
This document contains information about the functions of the bile, small intestine, and large intestine. It includes summaries of the properties and composition of bile, as well as its digestive, absorptive, excretory, and other functions. It also describes the functional anatomy of the small intestine, its roles in digestion and absorption of nutrients, and how food exits into the large intestine. Finally, it outlines the absorptive, excretory, secretory, synthetic and other functions of the large intestine, including its role in forming feces and the importance of dietary fiber.
Respiration is regulated by both nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that collect sensory information and control respiratory muscles. There are four respiratory centers - the inspiratory and expiratory centers in the medulla, and the pneumotaxic and apneustic centers in the pons. The chemical mechanism involves central and peripheral chemoreceptors that detect changes in blood oxygen, carbon dioxide, and hydrogen ion levels and stimulate the respiratory centers.
The human respiratory system consists of the nose, pharynx, larynx, trachea, bronchi, lungs, and alveoli. The nose and nasal cavity warm and filter incoming air. The pharynx and larynx are passageways that lead to the trachea, which divides into the left and right bronchi and further branches into bronchioles and alveoli within the lungs. Gas exchange occurs in the alveoli, where oxygen passes into the bloodstream and carbon dioxide passes out.
1. The mechanics of breathing involve reversing pressure gradients between the alveoli and atmosphere through cyclic respiratory muscle activity to allow air flow into and out of the lungs.
2. Three important pressures in respiration are atmospheric pressure, intra-alveolar pressure, and intra-pleural pressure.
3. Lung volumes include tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume. Lung capacities include functional residual capacity, inspiratory capacity, expiratory capacity, and total lung capacity.
The document summarizes the nervous and chemical mechanisms that regulate respiration. There are two main mechanisms:
1. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that receive input from afferent nerves and control respiration through efferent nerves that stimulate the diaphragm and intercostal muscles.
2. The chemical mechanism senses changes in blood gases through central and peripheral chemoreceptors. Central chemoreceptors in the brain stem detect increased carbon dioxide, while peripheral chemoreceptors in the carotid and aortic arteries detect low oxygen levels. Both trigger the respiratory centers to increase breathing rate.
The respiratory system has several functions including inhaling oxygen and exhaling carbon dioxide. It is comprised of organs like the nasal cavity, pharynx, larynx, trachea, bronchial tubes, and lungs. The nasal cavity warms and humidifies air before it reaches the lungs. The pharynx is shared by the respiratory and digestive systems. The larynx contains the vocal cords which produce sound. The trachea transports air to the bronchi and lungs. In the lungs, bronchioles divide into alveoli where gas exchange occurs across the respiratory membrane.
This document defines and describes the different types of dead space in the lungs, including anatomical, physiological, alveolar, and apparatus dead space. It explains that physiological dead space is greater than anatomical dead space due to the inclusion of alveolar dead space. The document also outlines methods to measure anatomical and physiological dead space, such as Fowler's method and Bohr's equation. Factors that can influence the amounts of anatomical and alveolar dead space are also discussed.
This document discusses the two main mechanisms that control respiration: the neural and chemical mechanisms. It describes in detail the various centers in the brainstem that control respiration, including the dorsal respiratory group, ventral respiratory group, pneumotaxic center, and apneustic center. It also discusses the voluntary, automatic, and reflex control of respiration, including various reflexes like the Hering-Breuer reflex. Other factors that can affect respiration like sleep and receptors outside the respiratory system are also summarized.
The document summarizes pulmonary circulation and systemic circulation in the human body. It explains that humans have a two-circuit circulatory system, with one circuit for pulmonary circulation transporting deoxygenated blood from the heart to the lungs, and another for systemic circulation transporting oxygenated blood from the heart to the rest of the body. Pulmonary circulation transports deoxygenated blood from the vena cavae to the lungs for oxygenation, then back to the left side of the heart. Systemic circulation then carries the oxygenated blood from the left ventricle through the aorta and arteries to tissues throughout the body, and returns deoxygenated blood back to the right atrium through the vena cava
The human body is composed primarily of fluids, with water making up about two-thirds of the total body weight. The body's fluids are divided into two main compartments: intracellular fluid (ICF) and extracellular fluid (ECF). ICF makes up about 40% of total body water and is contained within cells, while ECF comprises around 20% and includes interstitial fluid, plasma, and transcellular fluids such as cerebrospinal fluid. ECF volume can be measured using substances that remain in the extracellular space, while total body water and plasma volume are determined through the dilution of markers distributed throughout the body's water compartments. Proper fluid balance is essential for acid-base regulation, electrolyte levels
The document describes the structure and function of the respiratory system. It outlines the key components including the trachea, bronchi, bronchioles, alveoli, diaphragm, and intercostal muscles. It explains that inspiration occurs when the diaphragm and intercostal muscles contract, expanding the lungs to allow air entry. Expiration is the reverse process as these muscles relax and the lungs recoil, pushing air out. Gases are exchanged between the alveoli and blood via diffusion down a concentration gradient.
The respiratory system includes the nose, mouth, pharynx, larynx, trachea, bronchi, lungs and diaphragm. Air enters through the nose, where it is warmed and filtered before reaching the pharynx and larynx. The trachea divides into bronchi that branch into smaller airways ending in alveoli in the lungs. Gas exchange occurs in the alveoli as oxygen passes into the blood and carbon dioxide passes out. The diaphragm and rib cage work together to inhale and exhale air during breathing.
This document discusses oxygen transport from the atmosphere to tissues. It describes how oxygen is absorbed in the lungs and bound to hemoglobin to be carried by the blood. The oxyhemoglobin dissociation curve is explained, showing how hemoglobin releases oxygen in tissues. Factors affecting oxygen diffusion and binding such as partial pressure gradients, carbon dioxide levels, 2,3-DPG, and fetal hemoglobin are covered. The document also briefly discusses oxygen toxicity and ischemia-reperfusion injury.
The respiratory system has several key functions including supplying oxygen to the body and removing carbon dioxide. It consists of breathing, which has two phases - inhalation that draws air into the lungs and exhalation that forces air out. Gas exchange occurs externally between the lungs and blood and internally between blood and tissues. Regulation of respiration maintains appropriate oxygen and carbon dioxide levels in the blood by adjusting breathing to meet metabolic demand.
Anatomy of Tracheobronchial Tree and Bronchopulmonary Segments with summary o...Jega Subramaniam
Edited version of my Presentation in College.
Hope its useful for you rather than sleeping in my desktop.
Sorry if there is any mistakes.
Thanks and god bless.
The pulmonary circulation transports deoxygenated blood from the right ventricle to the lungs where carbon dioxide is released and oxygen is absorbed. The pulmonary arteries branch extensively and have large diameters to accommodate the stroke volume from the right ventricle with low resistance. Blood flows through the pulmonary capillaries where gas exchange occurs before returning to the left atrium via the pulmonary veins. Regional blood flow is highest in the lower lungs and intermittent in the apices due to hydrostatic pressures. During exercise, blood flow increases throughout the lungs. Pulmonary edema can result from increased capillary pressure from left heart failure.
The document summarizes gas exchange and oxygen transport in the human body. It discusses how (1) oxygen is extracted from the air and transported via the lungs to the blood, where it is carried by hemoglobin to tissues, and (2) carbon dioxide is transported in reverse from tissues to the lungs. Key aspects covered include alveolar gas transfer, the oxygen cascade, partial pressures of gases, diffusion principles, hemoglobin binding of oxygen and factors affecting it like pH, temperature and carbon monoxide.
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
The document summarizes several metabolic functions of the lungs beyond gas exchange. The lungs play roles in defense against pathogens, maintenance of water and temperature balance, acid-base regulation, and metabolism of various substances. The lungs are protected by physical and immunological defenses that clear pathogens. They also help regulate water loss, heat loss, carbon dioxide levels, and other substances that impact blood pressure, clotting, and hormone levels. Overall, the lungs perform important metabolic functions beyond respiration.
The document describes the structure and features of the heart chambers. It states that the heart is composed of 4 chambers - the right atrium, right ventricle, left atrium, and left ventricle. Blood enters the atria and is then pumped into the ventricles. From the left ventricle, blood passes into the aorta for systemic circulation, and from the right it enters the pulmonary circulation via the pulmonary arteries. Each chamber has distinct internal and external features and relations to other cardiac structures. The septa divide the atrial and ventricular chambers.
The cardiac cycle describes the sequence of events in one heartbeat. It involves systole, the contraction of the ventricles, and diastole, the relaxation of the ventricles. During atrial systole, the atria contract and blood passes to the relaxed ventricles. During ventricular systole, the ventricle walls contract and force blood out through the arteries. During diastole, the ventricles relax and blood flows back into the atria from the veins, completing the cycle.
This document provides an overview of respiratory physiology, covering the definition and function of respiration, the steps of respiration, the structure and function of the conducting and respiratory zones of the lungs, lung volumes and capacities, mechanics of breathing, gas exchange, transport of oxygen and carbon dioxide in the blood and tissues, and control of breathing. Key points include that respiration involves the exchange of oxygen and carbon dioxide between the environment and body cells, occurring in five steps including ventilation, diffusion, transport, and cellular respiration. Gas exchange takes place in the alveoli via differences in partial pressures and is facilitated by a large surface area and thin diffusion barrier. Oxygen is transported in both dissolved and hemoglobin-bound forms in the blood, while carbon
Respiration is regulated by both nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that collect sensory information and control respiratory muscles. There are four respiratory centers - the inspiratory and expiratory centers in the medulla, and the pneumotaxic and apneustic centers in the pons. The chemical mechanism involves central and peripheral chemoreceptors that detect changes in oxygen, carbon dioxide, and hydrogen ion levels in the blood and stimulate the respiratory centers.
Regulation of ventilation Dr. MADHUKIRAN, MD.PULMONOLOGYDr. Madhu Kiran
The document summarizes the regulation of ventilation through nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that control respiratory muscles. The chemical mechanism involves chemoreceptors that detect changes in oxygen, carbon dioxide, and hydrogen ion levels in the blood and stimulate the respiratory centers. Central chemoreceptors in the medulla are sensitive to increased hydrogen ions, while peripheral chemoreceptors detect reduced oxygen levels and stimulate breathing to rectify the lack of oxygen. Together the nervous and chemical mechanisms tightly regulate breathing to maintain appropriate gas exchange.
The document summarizes the nervous and chemical mechanisms that regulate respiration. There are two main mechanisms:
1. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that receive input from afferent nerves and control respiration through efferent nerves that stimulate the diaphragm and intercostal muscles.
2. The chemical mechanism senses changes in blood gases through central and peripheral chemoreceptors. Central chemoreceptors in the brain stem detect increased carbon dioxide, while peripheral chemoreceptors in the carotid and aortic arteries detect low oxygen levels. Both trigger the respiratory centers to increase breathing rate.
The respiratory system has several functions including inhaling oxygen and exhaling carbon dioxide. It is comprised of organs like the nasal cavity, pharynx, larynx, trachea, bronchial tubes, and lungs. The nasal cavity warms and humidifies air before it reaches the lungs. The pharynx is shared by the respiratory and digestive systems. The larynx contains the vocal cords which produce sound. The trachea transports air to the bronchi and lungs. In the lungs, bronchioles divide into alveoli where gas exchange occurs across the respiratory membrane.
This document defines and describes the different types of dead space in the lungs, including anatomical, physiological, alveolar, and apparatus dead space. It explains that physiological dead space is greater than anatomical dead space due to the inclusion of alveolar dead space. The document also outlines methods to measure anatomical and physiological dead space, such as Fowler's method and Bohr's equation. Factors that can influence the amounts of anatomical and alveolar dead space are also discussed.
This document discusses the two main mechanisms that control respiration: the neural and chemical mechanisms. It describes in detail the various centers in the brainstem that control respiration, including the dorsal respiratory group, ventral respiratory group, pneumotaxic center, and apneustic center. It also discusses the voluntary, automatic, and reflex control of respiration, including various reflexes like the Hering-Breuer reflex. Other factors that can affect respiration like sleep and receptors outside the respiratory system are also summarized.
The document summarizes pulmonary circulation and systemic circulation in the human body. It explains that humans have a two-circuit circulatory system, with one circuit for pulmonary circulation transporting deoxygenated blood from the heart to the lungs, and another for systemic circulation transporting oxygenated blood from the heart to the rest of the body. Pulmonary circulation transports deoxygenated blood from the vena cavae to the lungs for oxygenation, then back to the left side of the heart. Systemic circulation then carries the oxygenated blood from the left ventricle through the aorta and arteries to tissues throughout the body, and returns deoxygenated blood back to the right atrium through the vena cava
The human body is composed primarily of fluids, with water making up about two-thirds of the total body weight. The body's fluids are divided into two main compartments: intracellular fluid (ICF) and extracellular fluid (ECF). ICF makes up about 40% of total body water and is contained within cells, while ECF comprises around 20% and includes interstitial fluid, plasma, and transcellular fluids such as cerebrospinal fluid. ECF volume can be measured using substances that remain in the extracellular space, while total body water and plasma volume are determined through the dilution of markers distributed throughout the body's water compartments. Proper fluid balance is essential for acid-base regulation, electrolyte levels
The document describes the structure and function of the respiratory system. It outlines the key components including the trachea, bronchi, bronchioles, alveoli, diaphragm, and intercostal muscles. It explains that inspiration occurs when the diaphragm and intercostal muscles contract, expanding the lungs to allow air entry. Expiration is the reverse process as these muscles relax and the lungs recoil, pushing air out. Gases are exchanged between the alveoli and blood via diffusion down a concentration gradient.
The respiratory system includes the nose, mouth, pharynx, larynx, trachea, bronchi, lungs and diaphragm. Air enters through the nose, where it is warmed and filtered before reaching the pharynx and larynx. The trachea divides into bronchi that branch into smaller airways ending in alveoli in the lungs. Gas exchange occurs in the alveoli as oxygen passes into the blood and carbon dioxide passes out. The diaphragm and rib cage work together to inhale and exhale air during breathing.
This document discusses oxygen transport from the atmosphere to tissues. It describes how oxygen is absorbed in the lungs and bound to hemoglobin to be carried by the blood. The oxyhemoglobin dissociation curve is explained, showing how hemoglobin releases oxygen in tissues. Factors affecting oxygen diffusion and binding such as partial pressure gradients, carbon dioxide levels, 2,3-DPG, and fetal hemoglobin are covered. The document also briefly discusses oxygen toxicity and ischemia-reperfusion injury.
The respiratory system has several key functions including supplying oxygen to the body and removing carbon dioxide. It consists of breathing, which has two phases - inhalation that draws air into the lungs and exhalation that forces air out. Gas exchange occurs externally between the lungs and blood and internally between blood and tissues. Regulation of respiration maintains appropriate oxygen and carbon dioxide levels in the blood by adjusting breathing to meet metabolic demand.
Anatomy of Tracheobronchial Tree and Bronchopulmonary Segments with summary o...Jega Subramaniam
Edited version of my Presentation in College.
Hope its useful for you rather than sleeping in my desktop.
Sorry if there is any mistakes.
Thanks and god bless.
The pulmonary circulation transports deoxygenated blood from the right ventricle to the lungs where carbon dioxide is released and oxygen is absorbed. The pulmonary arteries branch extensively and have large diameters to accommodate the stroke volume from the right ventricle with low resistance. Blood flows through the pulmonary capillaries where gas exchange occurs before returning to the left atrium via the pulmonary veins. Regional blood flow is highest in the lower lungs and intermittent in the apices due to hydrostatic pressures. During exercise, blood flow increases throughout the lungs. Pulmonary edema can result from increased capillary pressure from left heart failure.
The document summarizes gas exchange and oxygen transport in the human body. It discusses how (1) oxygen is extracted from the air and transported via the lungs to the blood, where it is carried by hemoglobin to tissues, and (2) carbon dioxide is transported in reverse from tissues to the lungs. Key aspects covered include alveolar gas transfer, the oxygen cascade, partial pressures of gases, diffusion principles, hemoglobin binding of oxygen and factors affecting it like pH, temperature and carbon monoxide.
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
The document summarizes several metabolic functions of the lungs beyond gas exchange. The lungs play roles in defense against pathogens, maintenance of water and temperature balance, acid-base regulation, and metabolism of various substances. The lungs are protected by physical and immunological defenses that clear pathogens. They also help regulate water loss, heat loss, carbon dioxide levels, and other substances that impact blood pressure, clotting, and hormone levels. Overall, the lungs perform important metabolic functions beyond respiration.
The document describes the structure and features of the heart chambers. It states that the heart is composed of 4 chambers - the right atrium, right ventricle, left atrium, and left ventricle. Blood enters the atria and is then pumped into the ventricles. From the left ventricle, blood passes into the aorta for systemic circulation, and from the right it enters the pulmonary circulation via the pulmonary arteries. Each chamber has distinct internal and external features and relations to other cardiac structures. The septa divide the atrial and ventricular chambers.
The cardiac cycle describes the sequence of events in one heartbeat. It involves systole, the contraction of the ventricles, and diastole, the relaxation of the ventricles. During atrial systole, the atria contract and blood passes to the relaxed ventricles. During ventricular systole, the ventricle walls contract and force blood out through the arteries. During diastole, the ventricles relax and blood flows back into the atria from the veins, completing the cycle.
This document provides an overview of respiratory physiology, covering the definition and function of respiration, the steps of respiration, the structure and function of the conducting and respiratory zones of the lungs, lung volumes and capacities, mechanics of breathing, gas exchange, transport of oxygen and carbon dioxide in the blood and tissues, and control of breathing. Key points include that respiration involves the exchange of oxygen and carbon dioxide between the environment and body cells, occurring in five steps including ventilation, diffusion, transport, and cellular respiration. Gas exchange takes place in the alveoli via differences in partial pressures and is facilitated by a large surface area and thin diffusion barrier. Oxygen is transported in both dissolved and hemoglobin-bound forms in the blood, while carbon
Respiration is regulated by both nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that collect sensory information and control respiratory muscles. There are four respiratory centers - the inspiratory and expiratory centers in the medulla, and the pneumotaxic and apneustic centers in the pons. The chemical mechanism involves central and peripheral chemoreceptors that detect changes in oxygen, carbon dioxide, and hydrogen ion levels in the blood and stimulate the respiratory centers.
Regulation of ventilation Dr. MADHUKIRAN, MD.PULMONOLOGYDr. Madhu Kiran
The document summarizes the regulation of ventilation through nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that control respiratory muscles. The chemical mechanism involves chemoreceptors that detect changes in oxygen, carbon dioxide, and hydrogen ion levels in the blood and stimulate the respiratory centers. Central chemoreceptors in the medulla are sensitive to increased hydrogen ions, while peripheral chemoreceptors detect reduced oxygen levels and stimulate breathing to rectify the lack of oxygen. Together the nervous and chemical mechanisms tightly regulate breathing to maintain appropriate gas exchange.
1) Respiration is regulated by the nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla oblongata and pons that collect sensory information and determine signals to respiratory muscles.
2) There are four respiratory centers - the inspiratory and expiratory centers in the medulla, and the pneumotaxic and apneustic centers in the pons. The inspiratory center controls inspiration while the expiratory center controls expiration.
3) The chemical mechanism is operated by central and peripheral chemoreceptors that detect changes in blood oxygen, carbon dioxide, and hydrogen ion levels and stimulate the respiratory centers.
Regulation of Respiration - Animal PhysiologyMuhammad Yousaf
This document contain detailed study about The Regulation of Respiration and it covers all of the aspects of terms and topics related to regulation of respiration.
The document summarizes the regulation of respiration through nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla and pons that receive sensory information and control respiratory muscles. The chemical mechanism involves chemoreceptors that detect changes in blood oxygen, carbon dioxide, and hydrogen ion levels. Central chemoreceptors in the brainstem are sensitive to increased carbon dioxide levels, while peripheral chemoreceptors respond to decreased oxygen levels. Together the nervous and chemical mechanisms work to regulate breathing and maintain appropriate gas exchange.
1. Regulation of respiration involves nervous and chemical mechanisms, with respiratory centers in the brainstem controlling breathing via nerves and chemoreceptors detecting blood gas levels.
2. Fetal respiration relies on oxygen transfer through the plumbcenta rather than lung function. Neonatal respiration requires adaptations as the lungs begin gas exchange and breathing independently.
3. Respiration can be modified in unusual environments through adaptations like increased lung capacity at high altitudes or anaerobic pathways in low oxygen conditions.
The document summarizes control of respiration through three main points:
1) Respiration is controlled by centers in the brainstem that generate rhythmic breathing patterns and are influenced by higher brain areas. The medullary respiratory center contains inspiratory and expiratory neurons that drive the respiratory cycle.
2) Respiration is regulated automatically by chemoreceptors sensitive to oxygen, carbon dioxide, and hydrogen ion levels as well as by non-chemical receptors in the lungs and muscles that sense stretch and movement. Changes in chemical levels stimulate breathing via peripheral and central chemoreceptors.
3) Voluntary control from the cortex allows conscious modification of breathing but the involuntary control system in the brainstem drives automatic breathing at rest and
The document summarizes the regulation of respiration through nervous and chemical mechanisms. The nervous mechanism involves respiratory centers located in the medulla and pons that control inspiration and expiration. Chemical regulation occurs through central and peripheral chemoreceptors that detect changes in blood oxygen, carbon dioxide, and hydrogen ion levels and stimulate the respiratory centers. Factors like exercise, voluntary control, and lung irritants can also affect respiration.
10 regulation and 11 . disturbances of respirationMilliot Ngoma
The document discusses the regulation of respiration through nervous and chemical mechanisms. The nervous mechanism involves respiratory centers in the medulla and pons that control inspiration and expiration. These centers integrate input from peripheral chemoreceptors, baroreceptors, and pulmonary stretch receptors. The chemical mechanism involves central and peripheral chemoreceptors that detect changes in blood gases like oxygen and carbon dioxide levels and stimulate respiration as needed. Together, the nervous and chemical mechanisms maintain appropriate gas exchange and acid-base balance through regulating respiratory rate, depth, and muscle activity.
The document summarizes the neural and chemical regulation of respiration. It describes the key respiratory centers in the medulla and pons that control breathing. These include the dorsal and ventral respiratory groups in the medulla and the apneustic and pneumotaxic centers in the pons. Peripheral chemoreceptors in the carotid body and aortic body and central chemoreceptors in the medulla detect changes in blood gases like CO2 and pH to modulate breathing. Increased CO2 and H+ stimulate these chemoreceptors to enhance the activity of the respiratory centers and increase ventilation.
This document summarizes the regulation of respiration through two main mechanisms: nervous and chemical. The nervous mechanism involves respiratory centers in the brainstem that control breathing rate and depth. The chemical mechanism involves chemoreceptors that detect changes in blood gases like oxygen and carbon dioxide levels, stimulating the respiratory centers to increase or decrease breathing. Central chemoreceptors in the brain are more sensitive to increased carbon dioxide while peripheral chemoreceptors in the carotid body strongly respond to decreased oxygen levels. Together these mechanisms maintain appropriate gas exchange and pH levels in the blood through adjustments to respiratory rate and depth.
1. The respiratory center located in the medulla contains inspiratory and expiratory neurons that generate rhythmic breathing movements.
2. Respiration is regulated by peripheral reflexes like the Hering-Breuer reflex, chemical factors like carbon dioxide and oxygen levels that influence the respiratory center, and higher brain centers.
3. An increase in carbon dioxide, hydrogen ions, or decrease in oxygen stimulates respiration to maintain homeostasis, while stretch receptors in the lungs inhibit inspiration when full.
Regulation of respiration (the guyton and hall physiology)Maryam Fida
Normal respiration is spontaneous and unconscious.
There are 4 groups of neurons on each side in the Pons and medulla oblongata which are involved in regulation of respiration. These include
1. Medullary centers
Dorsal respiratory group of neurons
Ventral respiratory group of neurons
2. Pontine centers
Pneumotaxic centre
Apneustic centre.
It contains “I”neurons which are inspiratory neurons.
It’s located in dorsal portion of medulla oblongata.
It also includes the nucleus of tractus solitarius which is the sensory termination of afferent fibers in 9th ( GLOSSOPHARYNGEAL NERVE) and 10th (VAGUS NERVE) cranial nerves.
They receive impulses from peripheral chemoreceptors, carotid and aortic baroreceptors and also other receptors in the lungs.
In this group inspiratory ramp signals are produced spontaneously.
If we cut the medulla oblongata from other parts of brain and also the afferent nerves which enter the medulla, still inspiratory ramp signals are produced which indicate it’s the inherent property of medulla.
Initially the signal is weak and then it progressively increases and then fades away.
Each ramp signal’s duration is 2 sec and then for 3 seconds there is no ramp signal.
So each cycle lasts for 5 seconds and there are 12 cycles /minute which is the respiratory rate.
Significance of the signal in the form of ramp is that it causes progressive expansion of the lungs. After production, these ramp signals are transmitted to the contra lateral motor neurons supplying the inspiratory muscles.
Rate and duration of inspiratory ramp signals is controlled by impulses from the Pneumotaxic centre and impulses from the lungs via vagi.
The document discusses control of respiration through the respiratory center located in the medulla oblongata and pons of the brain. It contains three main areas - the medullary rhythmicity area which controls breathing rhythm, the pneumotaxic area which regulates transition between inhalation and exhalation, and the apneustic area which stimulates deep inhalation. Chemoreceptors in the brain and bloodstream provide feedback to the respiratory center in response to oxygen and carbon dioxide levels to regulate breathing rate and depth.
The document summarizes regulation of respiration, including:
1- The respiratory center is located in the medulla and pons and contains three major neuron groups that control inspiration, expiration, and breathing depth. Peripheral chemoreceptors also detect oxygen levels and signal the respiratory center.
2- Carbon dioxide and hydrogen ions directly stimulate the respiratory center, with CO2 having a more potent effect. Low oxygen is detected by peripheral chemoreceptors and signals increased breathing.
3- During exercise, respiration increases to match oxygen needs through both chemical and neural signals to the respiratory center and muscles. Other factors like lung inflation and brain edema can also affect respiration. Periodic breathing disorders like Cheyne-S
The document summarizes regulation of respiration, including:
1- The respiratory center is located in the medulla and pons and contains three major neuron groups that control inspiration, expiration, and breathing depth. Peripheral chemoreceptors also detect oxygen levels and signal the respiratory center.
2- Chemical control of respiration, mainly by carbon dioxide and hydrogen ions, directly stimulates the respiratory center. Oxygen does not directly affect the center but is detected by peripheral chemoreceptors.
3- Other factors like exercise, lung inflation, brain edema, anesthesia, and irritant receptors can also influence respiration. Periodic breathing disorders like Cheyne-Stokes and sleep apnea involve irregular breathing patterns during
The document discusses regulation of respiration, including:
1. The respiratory center is located in the medulla oblongata and consists of inspiratory and expiratory neurons that generate rhythmic breathing patterns.
2. Breathing is also regulated by centers in the pons and hypothalamus as well as reflexes from lung stretch receptors, irritant receptors, and J-receptors in the lungs.
3. The tone and rhythm of breathing is controlled by chemoreceptors sensitive to oxygen, carbon dioxide, hydrogen ions and the autonomic nervous system through the vagus nerves.
This document describes an experiment to study various aspects of human breathing using a respiratory belt transducer. The experiment involves recording normal breathing and the effects of holding one's breath, hyperventilation, rebreathing exhaled gases, and the relationship between breathing and heart rate. Key aspects of breathing discussed include the roles of the diaphragm and intercostal muscles, gas exchange in the lungs and tissues, and central and peripheral chemoreceptors that regulate breathing in response to oxygen and carbon dioxide levels.
This document describes an experiment to investigate various aspects of human breathing using a respiratory belt transducer. The experiment involves recording normal breathing and the effects of holding one's breath after inhaling and exhaling. It also examines the effects of hyperventilation, rebreathing exhaled gases, and how breathing affects heart rate. The setup uses a respiratory belt around the abdomen connected to a PowerLab device to record breathing movements and a finger pulse transducer to record heart rate.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...Donc Test
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
2. Respiration is regulated by two
mechanisms:
• Nervous or neural mechanism
• Chemical mechanism
Nervous Mechanism:
• It involves respiratory centers, afferent and efferent nerves.
• Respiratory centers: The centres in the medulla oblongata and
pons that collects sensory information about the level of oxygen
and carbon dioxide in the blood and determines the signals to be
sent to the respiratory muscles.
• Stimulation of these respiratory muscles provide respiratory
movements which leads to alveolar ventilation.
• Respiratory centers are situated in the reticular formation of the
brainstem and depending upon the situation in brainstem, the
respiratory centers are classified into two groups:
1. Medullary centers
2. Pontine centers
3. There are two centers in each group:
• Medullary Centers:
A. Inspiratory center
B. Expiratory center
• Pontine Centers:
A. Pneumotaxic center
B. Apneustic center
4. Inspiratory center:
• Inspiratory center is situated in upper part of medulla
oblongata
• This center is also called dorsal group of respiratory neurons
• It is formed by nucleus of tractus solitarius
• Function: it is concerned with inspiration.
5.
6.
7. Pneumotaxic center:
• It is situated in upper Pons.
• It is formed by nucleus parabrachialis.
• Function: it controls medullary respiratory centers,
particularly the inspiratory center through
apneustic center. It always controls the activity of
inspiratory center so that duration of inspiration is
controlled.
8.
9. Apnuestic center:
• It is situated in lower Pons.
• Function: this center increases depth of inspiration
by acting directly on the inspiratory center.
10. Expiratory center:
• It is situated in medulla oblongata anterior and lateral to the
inspiratory center
• It is also called ventral group of respiratory neurons
• It is formed by neurons of nucleus ambiguous and nucleus
retro ambiguous
• Function: this center is inactive during quiet breathing and
inspiratory center is the active center, but during forced
breathing or when the inspiratory center is inhibited it
becomes active.
11.
12. Nervous connections of respiratory
centers:
Afferent pathway:
• Respiratory center receive afferent impulses
from different parts of the body according to
movements of thoracic cage and lungs.
• From peripheral chemoreceptor and
baroreceptor impulses are carried by
glossopharyngeal and vagus nerves to
respiratory center.
Efferent pathway:
• Nerve fiber from respiratory center leaves the
brain and descend in anterior part of lateral
column of spinal cord.
• These nerve fibers terminate in the motor
neurons in the anterior horn cells of the cervical
and thoracic segments of spinal cord.
• From motor neurons two sets of nerve fiber
arise which supplies particular muscle:
1. Phrenic nerve fibers: supplies diaphragm
2. The intercostal nerve fibers: supplies
intercostal muscles.
13. Factors affecting respiratory centers:
1) Impulses from higher centers: impulses from
higher center can stimulate or inhibit respiratory
centers directly.
14.
15.
16. 3) Impulses from ‘J’ receptors of lungs:
• ‘J’ receptors are juxtacapillary receptors which are present in wall
of the alveoli and have close contact with the pulmonary
capillaries.
• These receptors get stimulated during conditions like pulmonary
edema, pulmonary congestion, pneumonia as well as due to
exposure of exogenous and endogenous chemicals like histamine,
serotonin.
• Stimulation of ‘J’ receptor produces a reflex response called
dyspnea.
4) Impulses from irritant receptors of lungs:
• Irritant receptors are situated on the wall of bronchi and
bronchioles of lungs.
• They got stimulated by harmful chemicals like ammonia and sulfur
dioxide.
• Stimulation of irritant receptors produces reflex hyperventilation
along with bronchospasm which prevents entry of harmful
chemicals into the alveoli.
17. 5) Impulses from Proprioceptors:
• Proprioceptors are the receptors which give response to the
change in the position of different parts of the body.
• This receptors are situated in joints, muscles and tendons.
They get stimulated during exercise and sends impulses to the
cerebral cortex.
• Cerebral cortex in turn by activating medullary respiratory
centres causes hyperventilation.
6) Impulses from Thermoreceptors:
• Thermoreceptors give response to change in the body
temperature.
• They are cutaneous receptors namely cold and warmth
• When this receptors get stimulated they send signals to
cerebral cortex
• Cerebral cortex in turn stimulates respiratory centres and
causes hyperventilation.
18. 7) Impulses from pain receptors:
• Pain receptors give response to pain stimulus.
• Like other receptors this receptors also send impulses to the
cerebral cortex.
• Cerebral cortex in turn stimulates the respiratory centers ad
causes hyperventilation.
8) Cough reflex:
• This is a protective reflex caused by irritation of parts of the
respiratory tract beyond nose like larynx, trachea and bronchi.
• Irritation of any of this part causes stimulation of vagus nerve
and cough occurs.
• Cough begins with deep inspiration followed by forceful
expiration with closed glottis.
• So the intrapleural pressure rises above 100 mm Hg.
• Then, glottis is suddenly opened with explosive outflow of air
at a higher velocity. So the irritants may be expelled out of
the respiratory tract.
19. 9) Sneezing reflex:
• It is also a protective reflex which occurs due to the irritation
of nasal mucus membrane.
• During irritation of nasal mucus membrane, the olfactory
receptors and trigeminal nerve endings present in the nasal
mucosa are stimulated leading to sneezing.
• Sneezing starts with deep inspiration, followed by forceful
expiratory effort with opened glottis and the irritants are
expelled out of the respiratory tract.
10) Deglutition reflex:
• During swallowing of the food, the respiration is arrested for
a while.
• Temporary arrest of the respiration is called apnea and apnea
which occurs during swallowing called swallowing apnea or
deglutition apnea.
• This prevents entry of the food particles into the respiratory
tract.
20. Chemical Mechanism:
• The chemical mechanism of the respiration is operated
through the chemoreceptors.
Chemoreceptors:
• They are the receptors which give response to change
in the chemical constituents of blood like..
A. Hypoxia
B. Hypercapnea
C. Increased hydrogen ions concentration (decreased
blood pH)
• Chemoreceptors are classified into two groups:
1. Central chemoreceptors
2. Peripheral chemoreceptors
21. Central chemoreceptors
• They are situated in deeper part
of medulla oblongata, close to
the dorsal group of neurons.
• This area is known as
chemosensitive area and neurons
are called as chemoreceptors.
• They are in close contact with
blood and CSF.
Situation: Action:
• They are very sensitive to increase in
hydrogen ion concentration.
• Hydrogen ion cannot cross the blood
brain barrier and blood cerebrospinal
fluid barrier.
• On the other hand if carbon dioxide
increases in the blood as it is a gas it
can cross both the barrier easily and
after entering the brain it combines
with water to form carbonic acid.
• As carbonic acid is unstable, it
immediately dissociates into hydrogen
and bicarbonate ions.
• The hydrogen ion now stimulates the
central cemoreceptors which
stimulates dorsal group of respiratory
center (inspiratory group) and
increase rate and force of breathing.
The chemoreceptors present in the brain are called central
chemoreceptors.
22. Peripheral chemoreceptors:
Situation: Action:
• They are very sensitive to
reduction in partial pressure
of oxygen.
• Whenever, the partial
pressure of oxygen decreases
these chemoreceptors
become activated and send
impulses to inspiratory
center and stimulate them.
• Thereby increases rate and
force of respiration and
rectifies the lack of oxygen.
The receptors are present in peripheral portions of the body
that’s why called as peripheral chemoreceptors.