The document outlines the features of the PubChem database developed by NCBI, which provides biological information on small molecules. It describes how to search for bioassays, compounds, and substances, and highlights the availability of drug information, pharmacology, and literature references. Users are encouraged to explore curated content for in-depth research on specific drugs, exemplified by the exploration of the compound peramivir.

1. Developed by the National Centre for
Biotechnology (NCBI) this database provides
information on the biological activities of small
molecules.
Search tabs for BioAssay, Compound and Substance
data
Links to references in PubMed and the 3 core NCBI
source databases;
Detailed record for substances included drug
information, pharmacology and curated literature.
University Library

2. Start with search in UWA OneSearch for “PubChem”
and jump out to the database from there. Enter you search term into the PubChem
search box:

3. Here we see 4 search results identified as Compound data

4. Opening up the summary information of the first quickly
identifies the active drug as Perimiver
Clicking on “Drug Information” reveals and
reinforces the active agent is “Peramivir”

5. This was the 3rd
record in our 4
results.
Here are the sample links to Drug and
Pharmacological Information

6. Focus in on the Depositor Literature Links and Curated Content in Pubmed
The curated content in
particular can provide a
good starting point to
further research on your
active drug and its uses.

7. Explore other content areas for this compound
Some may be specifically useful to
answering chemistry questions
about your drug.