Peptic ulcers form in the lining of the stomach, esophagus, or small intestine. Around 80% of ulcers are caused by Helicobacter pylori bacteria. Symptoms include abdominal pain, nausea, and vomiting of blood. Diagnosis involves tests to detect H. pylori infection and endoscopy to view the ulcers. Treatment focuses on eliminating H. pylori with antibiotics and reducing acid with proton pump inhibitors or H2 blockers to promote healing. Lifestyle changes and medications that protect the stomach lining can also help treat peptic ulcers.
Slide set for medical students discussing the physiology and pharmacology of nausea and vomiting. Provided by Professor John A Peters, University of Dundee.
Anatomy and Physiology of the GI System, Hormonal Control, Upper GI Tract Disorders, Gallbladder Disorders, Liver Disorders, Pancreatic Disorders, Lower GI Tract Disorders
This presentation is about peptic ulcer disease , including:Pathomorphology,etiology,symptoms,complications,diagnosis and pharmacotherapy,asurgical intervention and prevention...
This presentation is to help readers to be equipped with knowledge on predisposing factor to peptic ulcer disease and how it can be managed in the clinical/hospital setup.
This PPT covers the Pathophysiology of Peptic ulcer. It includes factors causing peptic ulcer, factors causing peptic ulcer, diagnosis and complications of peptic ulcer.
In this slide, you can understand the concept of Nausea and vomiting normally called "puke.''
Difference between Nausea and vomiting.
Causes of Vomiting.
Diet in Vomiting
Treatment in Vomiting.
Treatment of Vomiting in Pregnancy.
PPT download link.
https://drive.google.com/open?id=1beZMVQ75fdiGJlJDbGJKK3MGio6zgpLfTu9flkBSutk
Video Link:
https://youtu.be/ZvUiGpjt3zc
Peptic ulcer ( a medical study)- definition, causes, pathophysiology etc martinshaji
Peptic ulcers include:
Gastric ulcers that occur on the inside of the stomach
Esophageal ulcers that occur inside the hollow tube (esophagus) that carries food from your throat to your stomach
Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)
It's a myth that spicy foods or a stressful job can cause peptic ulcers. Doctors now know that a bacterial infection or some medications — not stress or diet — cause most peptic ulcers.
this is a detailed study on peptic ulcer
please comment
thank you
Slide set for medical students discussing the physiology and pharmacology of nausea and vomiting. Provided by Professor John A Peters, University of Dundee.
Anatomy and Physiology of the GI System, Hormonal Control, Upper GI Tract Disorders, Gallbladder Disorders, Liver Disorders, Pancreatic Disorders, Lower GI Tract Disorders
This presentation is about peptic ulcer disease , including:Pathomorphology,etiology,symptoms,complications,diagnosis and pharmacotherapy,asurgical intervention and prevention...
This presentation is to help readers to be equipped with knowledge on predisposing factor to peptic ulcer disease and how it can be managed in the clinical/hospital setup.
This PPT covers the Pathophysiology of Peptic ulcer. It includes factors causing peptic ulcer, factors causing peptic ulcer, diagnosis and complications of peptic ulcer.
In this slide, you can understand the concept of Nausea and vomiting normally called "puke.''
Difference between Nausea and vomiting.
Causes of Vomiting.
Diet in Vomiting
Treatment in Vomiting.
Treatment of Vomiting in Pregnancy.
PPT download link.
https://drive.google.com/open?id=1beZMVQ75fdiGJlJDbGJKK3MGio6zgpLfTu9flkBSutk
Video Link:
https://youtu.be/ZvUiGpjt3zc
Peptic ulcer ( a medical study)- definition, causes, pathophysiology etc martinshaji
Peptic ulcers include:
Gastric ulcers that occur on the inside of the stomach
Esophageal ulcers that occur inside the hollow tube (esophagus) that carries food from your throat to your stomach
Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)
It's a myth that spicy foods or a stressful job can cause peptic ulcers. Doctors now know that a bacterial infection or some medications — not stress or diet — cause most peptic ulcers.
this is a detailed study on peptic ulcer
please comment
thank you
Peptic ulcers are sores that develop in the lining of the stomach, lower esophagus, or small intestine. They're usually formed as a result of inflammation caused by the bacteria H. pylori, as well as from erosion from stomach acids. Peptic ulcers are a fairly common health problem.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
5. Peptic ulcer:
Def:
erosion in the lining (mucosa) of the digestive tract,
typically in the stomach, first part of the small intestine or
occasionally the lower esophagus.
An ulcer in the stomach is known as a gastric ulcer while
that in the first part of the intestines is known as
a duodenal ulcer.
an ulcer in the esophagus is called Esophageal ulcer.
6. Mucous layer
Coats and lines the stomach
First line of defense
Bicarbonate
Neutralizes acid
Prostaglandins
Hormone-like substances that keep blood vessels dilated for good blood flow
Thought to stimulate mucus and bicarbonate production
Stomach Defense Systems
7.
8.
9. Difference between gastric and
duodenal ulcer:
Gastric Ulcers: Pain occurs 1-2 hours after meals .
Pain usually does not wake patient.
Less common.
Usually occur in male as compared to female.
Duodenal Ulcers: Pain occurs 2-4 hours after meals.
Pain wakes up patient.
More common.
Occur in male and female equally.
Hematemesis more.
10. Causes of ulcer.
As many as 80% of ulcers are associated with Helicobacter pylori, a spiral-
shaped bacterium.
₪Ulcers can also be caused or worsened by drugs such as aspirin and
other NSAIDs.
In addition, smoking and certain other genetic and environmental
factors (such as medications) may influence the course of peptic
ulcer disease.
Psychological stress and dietary factors were once thought to be the
cause of ulcers.
11. Peptic ulcers are common and it has been estimated
that up to 10% of the population has as ulcer and
annual incidence of symptomatic peptic ulcer about
0.3%.
12.
13. Properties of h. pylori:
¤ Gram-negative, slow-growing organism
¤ about 3 micrometers long with a diameter of about
0.5 micrometers
¤has 4–6 flagella
¤ Helicobacter pylori is composed of a single circular chromosome with
1,667,867 base pairs, containing about 1590 coding regions
¤It is microaerophilic; that is, it requires oxygen, but at lower concentration
than is found in the atmosphere
¤It contains a hydrogenase which can be used to obtain energy by oxidizing
molecular hydrogen (H2) that is produced by intestinal bacteria.
¤
14. .
.
NAME OF SCIENTISTSYEAR
1900s
1958
1982
Lykoudis
(general practitioner in Greece)
Barry Marshall & Robin
Warren
(Two Australian scientists)
WORK
First discovery of human
gastric bacteria
Treatment of patients for peptic
ulcer disease with
antibiotics
Helicobacter pylori was
rediscovered as a causative
factor for ulcers
1987 First study showing that
eradication of the organism
reduces duodenal ulcer
recurrence
1994
National Institutes of Health
convened a Consensus Panel
that issued guidelines for
management of ulcer cancer,
taking H. pylori into account
1996 The Food and Drug
Administration approves the
first antibiotic for treatment
of ulcer disease
1997 Centers for Disease Control
and Prevention
Launched a national education
campaign to inform health
care providers and consumers
about the link between H.
pylori and ulcers.
15.
16. Symptoms of peptic ulcer:
abdominal pain may occur and In case of duodenal ulcers the pain appears about
three hours after taking a meal.
bloating and abdominal fullness;
nausea and vomiting;
weight loss;
hematemesis (vomiting of blood); this can occur due to bleeding directly from a
gastric ulcer, or from damage to the esophagus from severe/continuing vomiting.
Stomach pain wakes you up at night.
An early sense of fullness with eating
not wanting to eat because of pain.
17.
18. DIAGNOSIS of peptic ulcer:
Laboratory tests for H. pylori: Your doctor may recommend tests to
determine whether the bacterium H. pylori is present in your body. He
or she may look for H. pylori using a blood, stool or breath test. The
breath test is the most accurate. Blood tests are generally inaccurate
and should not be routinely used. For the breath test, you drink or eat
something containing radioactive carbon. H. pylori breaks down the
substance in your stomach. If you're infected with H. pylori, your
breath sample will contain the radioactive carbon in the form of
carbon dioxide.
19. Endoscopy.
Your doctor may use a scope to examine your
upper digestive system (endoscopy). During
endoscopy, your doctor passes a hollow tube
equipped with a lens (endoscope) down your
throat and into your esophagus, stomach and
small intestine. Using the endoscope, your
doctor looks for ulcers.
20.
21. Upper gastrointestinal series.
Sometimes called a barium swallow, this series of
X-rays of your upper digestive system creates
images of your esophagus, stomach and small
intestine. During the X-ray, you swallow a white
liquid (containing barium) that coats your
digestive tract and makes an ulcer more visible.
26. Treatment of peptic ulcer:
for peptic ulcers depends on the cause. Usually
treatment will involve killing the H. pylori bacterium, if
present, eliminating or reducing use of aspirin and
similar pain medications, if possible, and helping your
ulcer to heal with medication.
27. Antibiotic medications to kill H. pylori.
If H. pylori is found in your digestive tract,
your doctor may recommend antibiotics to
kill the bacterium. These may include
amoxicillin (Amoxil), clarithromycin
(Biaxin), metronidazole (Flagyl), tinidazole
(Tindamax), tetracycline (Tetracycline HCL)
and levofloxacin (Levaquin).
28.
29. Medications that block acid production
and promote healing.
Proton pump inhibitors: the protein pump inhibitor bind to
the enzyme or protein pump and suppress the secretion of hydrogen ions
into the gastric lumen. These drugs include the prescription and over-
the-counter medication omeprazole (Prilosec), lansoprazole (Prevacid),
rabeprazole (Aciphex), esomeprazole (Nexium) and pantoprazole
(Protonix).
Long-term use of proton pump inhibitors, particularly at high doses, may
increase your risk of hip, wrist and spine fracture. Ask your doctor
whether a calcium supplement may reduce this risk.
30.
31. Medications to reduce acid production.
(H-2) blockers = The histamine ,acetylcholine and gastrin are
responsible for production of HCL into the gastric lumen. These helps in
activation of protein kinases and helps to secrete hydrogen ions in
exchange for k into the lumen of the stomach. By blocking the histamine
causes reduce in secretion of HCL. reduce the amount of stomach acid
released into your digestive tract, which relieves ulcer pain and
encourages healing.
Available by prescription or over-the-counter, acid blockers include the
medications ranitidine (Zantac), famotidine (Pepcid), cimetidine
(Tagamet HB) and nizatidine (Axid AR).
32.
33. Antacid:
These are weak bases that react with gastric acid to form
water and a salt to neutralize the gastric acidity.
Commonly used antacid are aluminum hydroxide and
magnesium hydroxide .
Antacids can provide symptom relief, but generally aren't used
to heal your ulcer.
34.
35. Medications that protect the lining of
your stomach and small intestine:
M.A.O: prostaglandin E produces by the gastric mucosa, which
inhibits the secretion of acid and stimulates secretion of mucus
and bicarbonate. The deficiency of prostaglandin is thought to
be involved in the pathogenesis of peptic ulcer.
In some cases, your doctor may prescribe medications called
cytoprotective. These agents that help protect the tissues that
line your stomach and small intestine.
Options include the prescription medications sucralfate
(Carafate) and misoprostol (Cytotec).