The document discusses the anatomy and functions of the pericardium. It notes that the pericardium has two layers - an outer fibrous pericardium and inner serous pericardium. The serous pericardium further divides into the parietal and visceral layers, with the potential space between making up the pericardial cavity. The pericardium surrounds and protects the heart, and the pericardial fluid reduces friction during heart contractions. Clinical conditions involving the pericardium include pericarditis, pericardial effusion, cardiac tamponade, and pericardiocentesis to drain fluid.
Right Atrium of human heart
This PPT help to understand the external and internal structures of right atrium.
sulcus terminalis on external surface of rt atrium,
crista terminalis on internal side of rt. atrium,
interior is divided into rough anterior part and smooth posterior part ( sinus venarum)
superior and inferior venae cavae drains deoxygenated blood into rt. atrim
there is Eustachian valve to guard the opening of IVC and Thebesian valve to guard the opening of coronary sinus
septal wall presents fossa ovalis with its border limbus fossa ovalis
Here's a Presentation made by GROUP F on CORONARY CIRCULATION. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
right ventricle internal and external features-
interior is divided into inflowing and outflowing parts (infundibulum)
inflowing part is rough due to trabeculae corneae, - ridges, bridges, pillars. Chordae tendineae- are attached to pillars and cusps of tricuspid valve.
outflowing part is smooth, semilunar valve guards opening of pulmonary valve
Right Atrium of human heart
This PPT help to understand the external and internal structures of right atrium.
sulcus terminalis on external surface of rt atrium,
crista terminalis on internal side of rt. atrium,
interior is divided into rough anterior part and smooth posterior part ( sinus venarum)
superior and inferior venae cavae drains deoxygenated blood into rt. atrim
there is Eustachian valve to guard the opening of IVC and Thebesian valve to guard the opening of coronary sinus
septal wall presents fossa ovalis with its border limbus fossa ovalis
Here's a Presentation made by GROUP F on CORONARY CIRCULATION. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
right ventricle internal and external features-
interior is divided into inflowing and outflowing parts (infundibulum)
inflowing part is rough due to trabeculae corneae, - ridges, bridges, pillars. Chordae tendineae- are attached to pillars and cusps of tricuspid valve.
outflowing part is smooth, semilunar valve guards opening of pulmonary valve
Blood supply of head & neck. Arterial & venous anastomosesEneutron
1. The coomon carotid artery
a) topography
- carotid sinus
- carotid body
2. Neurovascular bundles of the neck
3. The external carotid artery
4. The internal carotid artery
- arterial supply of the brain
5. Arterial anastomoses head and neck
6. Veins of the head and neck
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
3. Introduction
Pericardium
The pericardium (Greek “around
heart”) is a fibroserous fluid filled
sac
Pericardium surrounds the
heart and the roots of the great
vessels( aorta, pulmonary artery,
Pulmonary veins ,SVC and IVC .
.
5. Layers of the pericardium
Image source : Google
Pericardium has 2
layers.
A. Fibrous pericardium
which is the outer sac
consist of the fibrous
tissue.
B. Serous pericardium
which Inner continuous
double layer of serous
membrane .
6. Fibrous pericardium
Image source : Google
Fibrous pericardium is a conical sac made up of fibrous tissue and is
relatively non-distensible.
Its rigid structure protects the heart against sudden overfilling and
prevents over expansion of the heart.
The parietal layer of serous pericardium is attached to its deep surface.
The apex is blunt and fused with the root of the great vessels.
The base is broad and blended with central tendon of diaphragm.
Anteriorly it is connected to body of sternum by sternopericardial
ligaments.
7. Image source : Google
Posteriorly attached with principal bronchi, esophagus and descending
thoracic aorta
On each side, it is related to the Mediastinal pleura, the Mediastinal
surface of the lung.
Aorta, SVC, Pulmonary arteries & Pulmonary veins receive fibrous
prolongations from fibrous layer.
As IVC enters the pericardium through the central tendon of diaphragm
So receives no covering from fibrous layer.
10. Serous pericardium
Image source : Google
Serous pericardium is thin, double-layered serous membrane lined by
mesothelium. It is made up of parietal serous layer and visceral serous
layer.
The outer layer or parietal pericardium is fused with fibrous
pericardium.
The inner layer or the visceral pericardium, or epicardium is fused to the
heart.
12. Pericardial cavity
Pericardial cavity
The pericardial cavity is a
potential space between the
parietal pericardium and the
visceral pericardium.
Pericardial cavity contains
only a thin film of serous
fluid known as pericardial
fluid.
13. Pericardial cavity
The pericardial fluid
reduces friction within the
pericardium by lubricating
the epicardial surface
allowing the membranes
to glide over each other
with each heart beat.
14. Pericardial sinuses
Pericardial sinuses
The Sinuses
of Pericardium lie between
the parietal and visceral layers
of serous pericardium and are
2 in number: Transverse sinus
& oblique sinus.
They’re created because of
the reflection of visceral layer
of serous pericardium around
great vessels of the heart.
15. Transverse pericardial sinuses
Image source : Google
Transverse sinus is the horizontal gap between the arterial ends of the heart
tubes in front and venous end behind .
transverse pericardial sinus separates the heart’s arterial outflow (aorta,
pulmonary trunk) from its venous inflow (superior vena cava, pulmonary
veins).
It is located: Posterior to the ascending aorta and pulmonary trunk
.Anterior to the superior vena cava. Superior to the left atrium.
During cardiac surgery, following the pericardial sac is opened anteriorly, a
finger is gone through the transverse sinus of pericardium.
A temporary ligature is gone through the transverse sinus around the aorta
and pulmonary trunk.
17. Oblique pericardial sinuses
Image source : Google
The oblique sinus of the pericardial cavity is a blind ending passage
posterior to the heart formed by the reflections of the visceral and parietal
pericardium onto the vessels traversing the space.
With the heart in its anatomical position and the dorsal pericardium intact,
it forms an inverted U-shaped recess that can be probed to reveal the
structures forming its walls:
20. Content of the pericardium
Image source : Google
Heart with cardiac vessels and nerves
Ascending aorta.
Pulmonary trunk.
Lower half of the superior vena cava.
Terminal part of the inferior vena cava
The terminal parts of the pulmonary veins
22. Functions of the pericardium
Image source : Google
Fixes the heart in the mediastinum and limits its motion.
Prevents overfilling of the heart.
Lubrication: A thin film of fluid between the two layers of the serous
pericardium reduces the friction generated by the heart as it moves within the
thoracic cavity
Protection from infection. The fibrous pericardium serves as a physical barrier
between the muscular body of the heart and adjacent organs prone to infection,
such as the lungs.
24. Blood supply of the pericardium
Arterial supply:
1. Pericardiophrenic artery
2. Musculophrenic artery .
3. Additional branches Bronchial ,Oesophageal , Superior phrenic arteries .
25. Pericardiophrenic artery is main artery supplies the pericardium and
diaphragm except the visceral pericardium.
Pericardiophrenic artery & musculophrenic artery are branches of internal
thoracic artery.
Note: Coronary artery supplies only the visceral layer of serous
pericardium(Epicardium).
28. Venous drainage of the pericardium
Deoxygenated blood is drained into the azygos venous system and
the Pericardiophrenic veins.
Azygos venous system and Pericardiophrenic veins are tributaries of
the brachiocephalic vein.
31. Nerve supply of the pericardium
Image source : Google
A. Phrenic nerve(C3-C5) provides somatic afferent innervation. It innervates
fibrous and parietal layer of serous pericardium. It is Sensitive to pain. Phrenic
nerve is a common source of referred pain. Thus shoulder pain is experienced
as a result of pericarditis.
B. The sympathetic trunk provides postganglionic vasomotor fibres. The
Visceral layer of Serous pericardium is innervated by branches of sympathetic
trunk
C. vagus nerve (ANS): Visceral layer (Epicardium) is pain insensitive.
35. Clinical relevance of the pericardium
Image source : Google
Pericarditis
Pericardial Effusion
Cardiac Tamponade
Pericardiocentesis
36. Pericarditis
Pericarditis
Pericarditis is an
Inflammation of the
lining around the
heart(the pericardium).
Pericardium causes
chest pain and
accumulation of fluid
around the heart .
38. Cardiac tamponade
Cardiac tamponade
Cardiac tamponade is a
clinical syndrome caused by
the accumulation of fluid in
the pericardial space.
It results in reduced
ventricular filling .
It is a medical emergency