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DR.G.SASI KUMAR
INDICATIONS
 As a treatment for hypoxemia due to hypoventilation,
  decreased gas exchange, ventilation perfusion
  abnormalities.

 To improve O2 supply to tissues when the disease process
  causes increased O2 demand.

 As specific treatment to certain conditions such as CO
  poisioning

 Survival of human at very low atm. pressure
OXYGEN DELIVERY DEVICES
  Classified depending on degree of dependancy.
Low        Supplemental oxygen        •Nasal prongs
dependancy alone is sufficient        •Face mask


Medium     Supplemental O2 and        •CPAP mask &
dependancy respiratory assistance     equipment


High       supplemental O2 and        •NIPPV
dependancy full respiratory support   •IPPV
                                      Requires intensive
                                      care
LOW DEPENDANCY DEVICES
 CLASSIFIED further into

   Variable performance devices—FiO2 variable


   Fixed performance devices—FiO2 fixed
VARIABLE PERFORMANCE DEVICES
Major determinants of FiO2 are—
 EQUIPMENT related:            PATIENT related:
1. Mask volume                1. Peak insiratory flow
2. O2 flow rate               2. Respiratory rate
3. Quality of mask fit        3. Tidal volume
4. Areas of holes in mask
 Variable performance devices—classified depending
 on reservoir capacity:
   No capacity devices
   Low capacity devices -- <100 ml
   Medium capacity devices – 100 – 250 ml
   High capacity devices – 250- 1500 ml
   Very high capacity devices -- >1500 ml
TYPE OF DEVICE            EXAMPLES


   no capacity       •Nasal prongs
                     •Nasal sponge tipped catheter
  low capacity       •Paediatric face mask
                     •Tracheastomy mask
                     •Swedish nose
medium capacity      •Standard adult face mask


 high capacity       •Face mask with reservoir bag
                     •T- bag
very high capacity   •Incubators
                     •Oxygen tents
NASAL CANNULA
 The nasal cannula can be rapidly and comfortably
 placed on most patients.

 Patients on long-term oxygen therapy most commonly
 use a nasal cannula.

 usually well tolerated, allows speech and
 eating/drinking, and is nonclaustrophobic.
 The actual FIO2 delivered to adults with nasal
 cannulas is determined by
   oxygen flow


   nasopharyngeal volume


   the patient's inspiratory flow
 Cannulas can be expected to provide inspired oxygen
 concentrations up to 30–35% with normal breathing
 and oxygen flows of 3–4 L/min.



 Usually flows greater than 5 L/min are poorly tolerated
 because of the discomfort of gas jetting into the nasal
 cavity and because of drying and crusting of the nasal
 mucosa.
FACE MASK WITH RESERVOIR BAG
 Two types of reservoir mask are commonly used:
    the partial rebreathing mask.


   the nonrebreathing mask.


 Mask reservoirs commonly hold approximately 600
 mL or less.
THE PARTIAL REBREATHING MASK.

 "part" of the patient's expired tidal volume refill the
  bag.

 Usually that gas is largely dead space that should not
  result in significant rebreathing of carbon dioxide.
THE NONREBREATHING MASK
 incorporates flap-type valves between the bag and
 mask and on at least one of the mask's exhalation
 ports.

 Reduces rebreathing of CO2.
 Typical minimum flows of oxygen are 10–15 L/min.


 FiO2 delivered with well fitting reservoir mask is 0.75
 to 0.90
FIXED PERFORMANCE DEVICES
 Fixed FiO2 is delivered that does not vary with
 respiratory pattern.

 These devices make use of venturi principle.
VENTURI:
  An equipment which includes
   a constriction whereby its
   cross section gradually
   decreases & then increases.

  Fluid flowing through a
   venturi will have pressure drop
   at the constriction where the
   velocity is higher.
BERNAULLI’S EFFECT:
   the lateral pressure of the fluid is least where
   the velocity is greatest

   Applications:
      Nebulizers
      Suction apparatus
      Venturi mask
FiO2 provided by   O2 flow rate   Amt. Of air   Total flow rate
venturi valve      ( L/min)       entrained     (L/min)
                                  (L/min)
      0.24                2              51             53



      0.28                4              41            45


       0.31               6              41            47



      0.35                8              37            45



      0.40                10             32            42



      0.60                15             15            30
 Low flow rate high air entrainment           low FiO2
    MORE RELABLE


 High flow rate     less amount of air entrained         high
 FiO2
   Since total flow rate is low, it may be overcome by
    patients peak inspiratory flow rate & rebreathing occurs.
   UNDERPERFORM by 5 to 10%
MEDIUM DEPENDANCY DEVICES
 Provides supplemental O2 and respiratory assistance


 Example : CPAP mask
CPAP MASK
 Tightly fitted on patients face with harness.


 Covers the nose and mouth with a good seal.


 Consist of 22 mm female taper inlet. “T” or “Y” shaped
  connector allows O2 delivery through one limb &
  CPAP valve on other limb.

 Provides 2.5 to 20 cms H2O pressure.
HIGH DEPENDANCY DEVICES
 Supplemental O2 & full respiratory support is
 provided.
   Non Invasive Positive Pressure Ventilation
   Invasive Positive Pressure Ventilation


 NIPPV -- For patients with central apnoea syndrome,
 neuro muscular & chest wall diseases.
         Increasingly being used for weaning from
 mechanical ventilation & acute respiratory failure.
HYPERBARIC OXYGEN THERAPY
 Carbon monoxide poisioning
 Gas gangrene
 Congenital cardiac anomalies
 Peripheral vascular insufficiency
 Cancer therapy
 Decompression sickness
ONE-PERSON
(MONOPLACE)
 HYPERBARIC CHAMBER
MULTIPLACE CHAMBERS
OXYGEN TOXICITY
 Pulmonary toxicity – O2 is a lung irritant producing
 inflammation & congestion – LORRAIN SMITH
 EFFECT.

 CNS toxicity – PAUL BERT EFFECT – localized muscle
 twitching of eyes, mouth & forehead  rigid tonic
 phase of convulsion  loss of conciousness 
 vigorous clonic contraction of muscle group of head ,
 neck , trunk & limbs
 Hypo ventilation -- primarily seen in patients with
 COPD who have chronic CO2 retention.

 Retinopathy of prematurity -- The recommended
 PaO2 for premature infants receiving oxygen are 50–80
 mm Hg (6.6–10.6 kPa).
HELIOX THERAPY
 The most popular mixtures are the 80%/20% and
  70%/30% helium–oxygen.
 They have densities that are 1.805 and 1.586 times less
  dense, respectively, compared with pure oxygen.
 In anesthetic practice, pressures needed to ventilate
 patients with small-diameter tracheal tubes (TTs) can
 be substantially reduced (halved) when the 80%/20%
 mixture is used.

 Patients with acute distress from upper airway–
 obstructing lesions may obtain relief until more
 definitive care can be delivered.

 The evidence is less convincing in treating lower
 airway obstruction in COPD and acute asthma.
thank you

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Oxygen therapy

  • 2. INDICATIONS  As a treatment for hypoxemia due to hypoventilation, decreased gas exchange, ventilation perfusion abnormalities.  To improve O2 supply to tissues when the disease process causes increased O2 demand.  As specific treatment to certain conditions such as CO poisioning  Survival of human at very low atm. pressure
  • 3. OXYGEN DELIVERY DEVICES  Classified depending on degree of dependancy. Low Supplemental oxygen •Nasal prongs dependancy alone is sufficient •Face mask Medium Supplemental O2 and •CPAP mask & dependancy respiratory assistance equipment High supplemental O2 and •NIPPV dependancy full respiratory support •IPPV Requires intensive care
  • 4. LOW DEPENDANCY DEVICES  CLASSIFIED further into  Variable performance devices—FiO2 variable  Fixed performance devices—FiO2 fixed
  • 5. VARIABLE PERFORMANCE DEVICES Major determinants of FiO2 are—  EQUIPMENT related:  PATIENT related: 1. Mask volume 1. Peak insiratory flow 2. O2 flow rate 2. Respiratory rate 3. Quality of mask fit 3. Tidal volume 4. Areas of holes in mask
  • 6.  Variable performance devices—classified depending on reservoir capacity:  No capacity devices  Low capacity devices -- <100 ml  Medium capacity devices – 100 – 250 ml  High capacity devices – 250- 1500 ml  Very high capacity devices -- >1500 ml
  • 7. TYPE OF DEVICE EXAMPLES no capacity •Nasal prongs •Nasal sponge tipped catheter low capacity •Paediatric face mask •Tracheastomy mask •Swedish nose medium capacity •Standard adult face mask high capacity •Face mask with reservoir bag •T- bag very high capacity •Incubators •Oxygen tents
  • 8. NASAL CANNULA  The nasal cannula can be rapidly and comfortably placed on most patients.  Patients on long-term oxygen therapy most commonly use a nasal cannula.  usually well tolerated, allows speech and eating/drinking, and is nonclaustrophobic.
  • 9.  The actual FIO2 delivered to adults with nasal cannulas is determined by  oxygen flow  nasopharyngeal volume  the patient's inspiratory flow
  • 10.  Cannulas can be expected to provide inspired oxygen concentrations up to 30–35% with normal breathing and oxygen flows of 3–4 L/min.  Usually flows greater than 5 L/min are poorly tolerated because of the discomfort of gas jetting into the nasal cavity and because of drying and crusting of the nasal mucosa.
  • 11. FACE MASK WITH RESERVOIR BAG  Two types of reservoir mask are commonly used:  the partial rebreathing mask.  the nonrebreathing mask.  Mask reservoirs commonly hold approximately 600 mL or less.
  • 12.
  • 13. THE PARTIAL REBREATHING MASK.  "part" of the patient's expired tidal volume refill the bag.  Usually that gas is largely dead space that should not result in significant rebreathing of carbon dioxide.
  • 14. THE NONREBREATHING MASK  incorporates flap-type valves between the bag and mask and on at least one of the mask's exhalation ports.  Reduces rebreathing of CO2.
  • 15.  Typical minimum flows of oxygen are 10–15 L/min.  FiO2 delivered with well fitting reservoir mask is 0.75 to 0.90
  • 16. FIXED PERFORMANCE DEVICES  Fixed FiO2 is delivered that does not vary with respiratory pattern.  These devices make use of venturi principle.
  • 17. VENTURI:  An equipment which includes a constriction whereby its cross section gradually decreases & then increases.  Fluid flowing through a venturi will have pressure drop at the constriction where the velocity is higher.
  • 18. BERNAULLI’S EFFECT:  the lateral pressure of the fluid is least where the velocity is greatest  Applications:  Nebulizers  Suction apparatus  Venturi mask
  • 19. FiO2 provided by O2 flow rate Amt. Of air Total flow rate venturi valve ( L/min) entrained (L/min) (L/min) 0.24 2 51 53 0.28 4 41 45 0.31 6 41 47 0.35 8 37 45 0.40 10 32 42 0.60 15 15 30
  • 20.
  • 21.  Low flow rate high air entrainment low FiO2  MORE RELABLE  High flow rate less amount of air entrained high FiO2  Since total flow rate is low, it may be overcome by patients peak inspiratory flow rate & rebreathing occurs.  UNDERPERFORM by 5 to 10%
  • 22. MEDIUM DEPENDANCY DEVICES  Provides supplemental O2 and respiratory assistance  Example : CPAP mask
  • 23. CPAP MASK  Tightly fitted on patients face with harness.  Covers the nose and mouth with a good seal.  Consist of 22 mm female taper inlet. “T” or “Y” shaped connector allows O2 delivery through one limb & CPAP valve on other limb.  Provides 2.5 to 20 cms H2O pressure.
  • 24. HIGH DEPENDANCY DEVICES  Supplemental O2 & full respiratory support is provided.  Non Invasive Positive Pressure Ventilation  Invasive Positive Pressure Ventilation  NIPPV -- For patients with central apnoea syndrome, neuro muscular & chest wall diseases. Increasingly being used for weaning from mechanical ventilation & acute respiratory failure.
  • 25. HYPERBARIC OXYGEN THERAPY  Carbon monoxide poisioning  Gas gangrene  Congenital cardiac anomalies  Peripheral vascular insufficiency  Cancer therapy  Decompression sickness
  • 28. OXYGEN TOXICITY  Pulmonary toxicity – O2 is a lung irritant producing inflammation & congestion – LORRAIN SMITH EFFECT.  CNS toxicity – PAUL BERT EFFECT – localized muscle twitching of eyes, mouth & forehead  rigid tonic phase of convulsion  loss of conciousness  vigorous clonic contraction of muscle group of head , neck , trunk & limbs
  • 29.  Hypo ventilation -- primarily seen in patients with COPD who have chronic CO2 retention.  Retinopathy of prematurity -- The recommended PaO2 for premature infants receiving oxygen are 50–80 mm Hg (6.6–10.6 kPa).
  • 30. HELIOX THERAPY  The most popular mixtures are the 80%/20% and 70%/30% helium–oxygen.  They have densities that are 1.805 and 1.586 times less dense, respectively, compared with pure oxygen.
  • 31.  In anesthetic practice, pressures needed to ventilate patients with small-diameter tracheal tubes (TTs) can be substantially reduced (halved) when the 80%/20% mixture is used.  Patients with acute distress from upper airway– obstructing lesions may obtain relief until more definitive care can be delivered.  The evidence is less convincing in treating lower airway obstruction in COPD and acute asthma.